Result of FASTA (omim) for pF1KE0553
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0553, 357 aa
  1>>>pF1KE0553 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9009+/-0.000401; mu= 18.2713+/- 0.025
 mean_var=61.5029+/-12.491, 0's: 0 Z-trim(111.6): 44  B-trim: 138 in 2/49
 Lambda= 0.163541
 statistics sampled from 20150 (20194) to 20150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.237), width:  16
 Scan time:  6.720

The best scores are:                                      opt bits E(85289)
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357) 2588 619.4 3.9e-177
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 1753 422.4 8.2e-118
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 1200 291.9 1.5e-78
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227) 1127 274.5 1.6e-73
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524)  902 221.7 2.9e-57
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386)  822 202.7 1.1e-51
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181)  804 198.3 1.1e-50
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199)  804 198.3 1.2e-50
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190)  710 176.1 5.6e-44
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442)  703 174.7 3.5e-43
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455)  677 168.6 2.5e-41
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457)  651 162.4 1.8e-39
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202)  530 133.6 3.6e-31
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317)  524 132.4 1.4e-30
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384)  524 132.4 1.6e-30
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198)  355 92.4 9.5e-19
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203)  337 88.1 1.8e-17
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203)  337 88.1 1.8e-17
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182)  336 87.8   2e-17
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183)  336 87.8   2e-17
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200)  336 87.9 2.1e-17
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200)  336 87.9 2.1e-17
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224)  335 87.7 2.8e-17
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188)  313 82.4 8.8e-16
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236)  310 81.8 1.7e-15
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236)  310 81.8 1.7e-15
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145)  307 80.9 1.9e-15
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191)  295 78.2 1.7e-14
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154)  249 67.3 2.6e-11
NP_001006667 (OMIM: 608993) DNA dC->dU-editing enz ( 101)  233 63.4 2.6e-10
XP_016884132 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 101)  233 63.4 2.6e-10


>>NP_001257340 (OMIM: 607110) DNA dC->dU-editing enzyme   (357 aa)
 initn: 2588 init1: 2588 opt: 2588  Z-score: 3301.2  bits: 619.4 E(85289): 3.9e-177
Smith-Waterman score: 2588; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 ELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQM
              250       260       270       280       290       300

              310       320       330       340       350       
pF1KE0 LRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
              310       320       330       340       350       

>>NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme APO  (382 aa)
 initn: 1753 init1: 1753 opt: 1753  Z-score: 2236.1  bits: 422.4 E(85289): 8.2e-118
Smith-Waterman score: 2528; 93.2% identity (93.5% similar) in 382 aa overlap (1-357:1-382)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
              190       200       210       220       230       240

                                       250       260       270     
pF1KE0 E-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
       :                         ::::::::::::::::::::::::::::::::::
NP_004 EAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
              250       260       270       280       290       300

         280       290       300       310       320       330     
pF1KE0 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
              310       320       330       340       350       360

         340       350       
pF1KE0 GLEEHSQALSGRLRAILQNQGN
       ::::::::::::::::::::::
NP_004 GLEEHSQALSGRLRAILQNQGN
              370       380  

>>NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme APO  (373 aa)
 initn: 1454 init1: 952 opt: 1200  Z-score: 1531.1  bits: 291.9 E(85289): 1.5e-78
Smith-Waterman score: 1504; 59.8% identity (76.6% similar) in 376 aa overlap (1-353:1-373)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       :.:..:: .::::::::  :: :.:::  :. .::::::: : : :    :. .::::::
NP_660 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
        .:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_660 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
       ::::::::::::::::::::::::::::: ::::::::::::.::: ::::::::.::::
NP_660 ARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAF
     120       130       140       150       160       170         

              190          200       210       220             230 
pF1KE0 LHRTLKEILRYLMD---PDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGT---W---VLM
       ::::::::::  :.   :  : :.:.:   .  : ...::. .: . . .   :   :. 
NP_660 LHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFR
     180       190       200       210       220       230         

                         240        250       260       270        
pF1KE0 DQ-----H-------MGFLCNE-LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
       .:     :       ....:.. :.:   :.:::. :::::    :::::  :: ....:
NP_660 NQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAGEVAEFLARHSNV
     240       250       260       270       280         290       

      280       290        300       310       320       330       
pF1KE0 RLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGL
        : ::.::.: . :  :.:.:. : . ::.: :: : .:.:::..::: .  ::.:: ::
NP_660 NLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGL
       300       310       320       330       340       350       

       340       350       
pF1KE0 EEHSQALSGRLRAILQNQGN
       . .   :...:. ::.    
NP_660 KYNFLFLDSKLQEILE    
       360       370       

>>XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU-edit  (227 aa)
 initn: 1125 init1: 952 opt: 1127  Z-score: 1441.1  bits: 274.5 E(85289): 1.6e-73
Smith-Waterman score: 1127; 82.6% identity (90.5% similar) in 190 aa overlap (1-190:1-189)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       :.:..:: .::::::::  :: :.:::  :. .::::::: : : :    :. .::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
        .:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_016 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYAF
       ::::::::::::::::::::::::::::: ::::::::::::.::: ::::::::.::::
XP_016 ARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAF
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
       ::::::::::                                                  
XP_016 LHRTLKEILRATSIHLRGRPPHSLGSPTWLLPSPWHNRICHKTGRKWA            
     180       190       200       210       220                   

>>XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU-edit  (524 aa)
 initn: 1156 init1: 415 opt: 902  Z-score: 1149.0  bits: 221.7 E(85289): 2.9e-57
Smith-Waterman score: 1339; 53.8% identity (71.0% similar) in 383 aa overlap (1-353:1-380)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       :.:..:: .::::::::  :: :.:::  :. .::::::: : : :    :. .::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRGQVY
               10        20        30        40         50         

               70         80        90       100       110         
pF1KE0 FEPQYHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
        : .:: :: :. ::    .:   . ...::..::.::  :.  .: ::.: :.::::: 
XP_016 SELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIF
      60        70        80        90       100       110         

     120       130       140           150       160       170     
pF1KE0 AARLYYYWERDYRRALCRLSQA--GAR--VKIMDYEEFAYCWENFVYNEGQQFMPWYKFD
       .:::::.:. ::..::  : :   : :  .:::.:.:: .:: .:::.. . : :: .. 
XP_016 VARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLP
     120       130       140       150       160       170         

         180       190       200       210       220       230     
pF1KE0 ENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHM
       . : .::  : ::::. ::: ::::::::.: :  :..:::::::::. : ::::..:. 
XP_016 KYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRR
     180       190       200       210       220       230         

         240                                250       260       270
pF1KE0 GFLCNE-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRA
       :::::.                         ::  : :::: : :::::::  :: :.  
XP_016 GFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAK
     240       250       260       270       280       290         

              280       290       300       310       320       330
pF1KE0 FLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCP
       :...: :: : ::.::::: .   .:.:. : .:::..:::::.::..:::::: .::::
XP_016 FISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCP
       300       310       320       330       340       350       

              340       350                                        
pF1KE0 FQPWDGLEEHSQALSGRLRAILQNQGN                                 
       :::::::.:::: ::::::::::                                     
XP_016 FQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPAPCLPLCSEPPLGSLLP
       360       370       380       390       400       410       

>>NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme APO  (386 aa)
 initn: 1076 init1: 749 opt: 822  Z-score: 1048.9  bits: 202.7 E(85289): 1.1e-51
Smith-Waterman score: 1482; 58.8% identity (74.0% similar) in 388 aa overlap (1-353:1-386)

               10        20        30        40        50          
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRG---
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_689 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL
               10        20        30        40        50        60

                 60        70        80        90       100        
pF1KE0 ---------QVYFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL
                .:::. . :::::::::::::.::: . :::::::::.::  ::.:...::
NP_689 PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL
               70        80        90       100       110       120

      110       120       130       140       150       160        
pF1KE0 SEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQF
       .::::::::::::::::: .::.: .: :: .:::::::::::.::::::::: :::: :
NP_689 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF
              130       140       150       160       170       180

      170       180       190          200       210       220     
pF1KE0 MPWYKFDENYAFLHRTLKEILRYLMD---PDTFTFNFNNDPLVLRRRQTYLCYEVERLDN
       :::::::.::: ::::::::::  :.   :  : :.:.:   .  : ...::. .:   .
NP_689 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH
              190       200       210       220       230       240

         230                         240        250       260      
pF1KE0 GTWVLM-----------DQH-------MGFLCNE-LDPAQIYRVTWFISWSPCFSWGCAG
        . :.            . :       ....:.. :.:   :.:::. :::::    :::
NP_689 HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAG
              250       260       270       280       290          

        270       280        290       300       310       320     
pF1KE0 EVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVY
       ::  :: ....: : ::.::. : .:  :.:.:  : . ::.:.:: : .:  :: .:::
NP_689 EVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVY
      300       310       320       330       340       350        

         330       340       350       
pF1KE0 RQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
        .  ::.:: ::. . . :. ::: :::    
NP_689 SDDEPFKPWKGLQTNFRLLKRRLREILQ    
      360       370       380          

>>NP_001257335 (OMIM: 607109) DNA dC->dU-editing enzyme   (181 aa)
 initn: 804 init1: 804 opt: 804  Z-score: 1030.6  bits: 198.3 E(85289): 1.1e-50
Smith-Waterman score: 902; 78.5% identity (82.6% similar) in 172 aa overlap (211-357:10-181)

              190       200       210       220       230       240
pF1KE0 LHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLCN
                                     :..:::::::::::::: : :::: ::: :
NP_001                      MEASPASGPRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
                                    10        20        30         

                                       250       260       270     
pF1KE0 E-------------------------LDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
       .                         ::::::::::::::::::::::::::::::::::
NP_001 QAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
      40        50        60        70        80        90         

         280       290       300       310       320       330     
pF1KE0 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWD
       :::::::::::::::::::::::::::::::::::::::::..:::::: .:::::::::
NP_001 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWD
     100       110       120       130       140       150         

         340       350       
pF1KE0 GLEEHSQALSGRLRAILQNQGN
       ::.:::::::::::::::::::
NP_001 GLDEHSQALSGRLRAILQNQGN
     160       170       180 

>>NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme APO  (199 aa)
 initn: 866 init1: 804 opt: 804  Z-score: 1030.1  bits: 198.3 E(85289): 1.2e-50
Smith-Waterman score: 960; 75.6% identity (80.3% similar) in 193 aa overlap (190-357:10-199)

     160       170       180       190       200       210         
pF1KE0 FVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYE
                                     :.::::  :: ::::    . :..::::::
NP_663                      MEASPASGPRHLMDPHIFTSNFNNG---IGRHKTYLCYE
                                    10        20           30      

     220       230       240                                250    
pF1KE0 VERLDNGTWVLMDQHMGFLCNE-------------------------LDPAQIYRVTWFI
       :::::::: : :::: ::: :.                         :::::::::::::
NP_663 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
         40        50        60        70        80        90      

          260       270       280       290       300       310    
pF1KE0 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
        100       110       120       130       140       150      

          320       330       340       350       
pF1KE0 EFEYCWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
       ::..:::::: .:::::::::::.:::::::::::::::::::
NP_663 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
        160       170       180       190         

>>NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme APO  (190 aa)
 initn: 676 init1: 676 opt: 710  Z-score: 910.5  bits: 176.1 E(85289): 5.6e-44
Smith-Waterman score: 710; 53.9% identity (74.3% similar) in 191 aa overlap (1-190:1-190)

               10        20        30        40         50         
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVK-IKRGRSNLLWDTGVFRGQV
       :::::::::. ::  ::: .:.:      :. ::::. :. ::: :: . : :::::.::
NP_055 MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKR-RSVVSWKTGVFRNQV
               10        20        30        40         50         

      60        70        80        90       100       110         
pF1KE0 YFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
         : . ::: ::::::: . :     .:.::..::.:::::....::::..: ::.::: 
NP_055 DSETHCHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIF
      60        70        80        90       100       110         

     120       130       140       150       160       170         
pF1KE0 AARLYYYWERDYRRALCRLSQAGARVKIMDYEEFAYCWENFVYNEGQQFMPWYKFDENYA
       .:::::.    :...:  ::: :. :.:::::.: :::::::::... : ::  .  :. 
NP_055 TARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPFKPWKGLKTNFR
     120       130       140       150       160       170         

     180       190       200       210       220       230         
pF1KE0 FLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHMGFLC
       .:.: :.: :.                                                 
NP_055 LLKRRLRESLQ                                                 
     180       190                                                 

>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit  (442 aa)
 initn: 1410 init1: 703 opt: 703  Z-score: 896.3  bits: 174.7 E(85289): 3.5e-43
Smith-Waterman score: 967; 60.3% identity (66.1% similar) in 257 aa overlap (1-188:1-256)

               10        20        30        40        50        60
pF1KE0 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
       :.:..:: .::::::::  :: :.:::  :. .::::::: : : :    :. .::::::
XP_011 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQVY
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KE0 FEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTISA
        .:..:::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 SQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
      60        70        80        90       100       110         

              130       140       150                              
pF1KE0 ARLYYYWERDYRRALCRLSQAGARVKIMDYE-----------------------------
       ::::::::::::::::::::::::::::: :                             
XP_011 ARLYYYWERDYRRALCRLSQAGARVKIMDDEGERWRGQGSVSGRNSMKDGWICNAMAGGV
     120       130       140       150       160       170         

                                                     160       170 
pF1KE0 ----------------------------------------EFAYCWENFVYNEGQQFMPW
                                               :::::::::::.::: ::::
XP_011 PGQPAGAGPALTATDSQETRPGSAGPGSGQSLTASCLFVSEFAYCWENFVYSEGQPFMPW
     180       190       200       210       220       230         

             180       190       200       210       220       230 
pF1KE0 YKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLM
       ::::.::::::::::::                                           
XP_011 YKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSP
     240       250       260       270       280       290         

>--
 initn: 1410 init1: 703 opt: 703  Z-score: 896.3  bits: 174.7 E(85289): 3.5e-43
Smith-Waterman score: 703; 50.3% identity (73.5% similar) in 185 aa overlap (5-189:257-441)

                                         10        20        30    
pF1KE0                           MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTW
                                     .::::: ::   :: .:.:    :::. .:
XP_011 NFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESW
        230       240       250       260       270       280      

           40        50        60        70        80        90    
pF1KE0 LCYEVKIKRGRSNLLWDTGVFRGQVYFEPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSW
       ::. ... . .: . :  ::::.::  : . ::: ::::::: . :     ...::..::
XP_011 LCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSW
        290       300       310       320       330       340      

          100       110       120       130       140       150    
pF1KE0 TPCPDCVAKLAEFLSEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDYEEFA
       .:::.:....::::..: ::.::: .:::::.:. ::...:  ::: :: :.:: :..: 
XP_011 SPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFK
        350       360       370       380       390       400      

          160       170       180       190       200       210    
pF1KE0 YCWENFVYNEGQQFMPWYKFDENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQT
       :::::::::. . : ::  .  :. ::   :.:::                         
XP_011 YCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE                        
        410       420       430       440                          

          220       230       240       250       260       270    
pF1KE0 YLCYEVERLDNGTWVLMDQHMGFLCNELDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQE




357 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:41:10 2016 done: Wed Nov  2 23:41:11 2016
 Total Scan time:  6.720 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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