Result of FASTA (omim) for pF1KE0352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0352, 530 aa
  1>>>pF1KE0352 530 - 530 aa - 530 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2575+/-0.000432; mu= 13.5186+/- 0.027
 mean_var=77.5222+/-15.689, 0's: 0 Z-trim(111.2): 41  B-trim: 616 in 1/50
 Lambda= 0.145667
 statistics sampled from 19676 (19714) to 19676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width:  16
 Scan time:  8.120

The best scores are:                                      opt bits E(85289)
NP_006612 (OMIM: 607826) adenosylhomocysteinase 2  ( 530) 3545 754.9 1.3e-217
XP_011538837 (OMIM: 607826) PREDICTED: adenosylhom ( 505) 3265 696.1 6.5e-200
NP_001229603 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229605 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229602 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_001229604 (OMIM: 607826) adenosylhomocysteinase ( 483) 3238 690.4 3.2e-198
NP_056143 (OMIM: 616520) adenosylhomocysteinase 3  ( 611) 3129 667.5 3.1e-191
NP_001124192 (OMIM: 616520) adenosylhomocysteinase ( 610) 3123 666.3 7.4e-191
NP_001124194 (OMIM: 616520) adenosylhomocysteinase ( 508) 3110 663.5 4.2e-190
NP_001124195 (OMIM: 616520) adenosylhomocysteinase ( 508) 3103 662.1 1.2e-189
XP_011514289 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_011514290 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_005250294 (OMIM: 616520) PREDICTED: adenosylhom ( 509) 3102 661.8 1.3e-189
XP_016867393 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867396 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867394 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
XP_016867395 (OMIM: 616520) PREDICTED: adenosylhom ( 404) 2619 560.3 3.9e-159
NP_001309015 (OMIM: 180960,613752) adenosylhomocys ( 434) 1494 323.9 6.2e-88
XP_011526958 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_011526960 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_011526959 (OMIM: 180960,613752) PREDICTED: aden ( 434) 1494 323.9 6.2e-88
XP_016883198 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1489 322.8 1.3e-87
XP_016883197 (OMIM: 180960,613752) PREDICTED: aden ( 432) 1489 322.8 1.3e-87
NP_000678 (OMIM: 180960,613752) adenosylhomocystei ( 432) 1489 322.8 1.3e-87
XP_011526961 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1437 311.9 2.3e-84
NP_001155238 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
XP_005260374 (OMIM: 180960,613752) PREDICTED: aden ( 404) 1437 311.9 2.3e-84
NP_001309014 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
NP_001309013 (OMIM: 180960,613752) adenosylhomocys ( 404) 1437 311.9 2.3e-84
XP_016883199 (OMIM: 180960,613752) PREDICTED: aden ( 306) 1070 234.7   3e-61


>>NP_006612 (OMIM: 607826) adenosylhomocysteinase 2 isof  (530 aa)
 initn: 3545 init1: 3545 opt: 3545  Z-score: 4027.8  bits: 754.9 E(85289): 1.3e-217
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 530 aa overlap (1-530:1-530)

               10        20        30        40        50        60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
              430       440       450       460       470       480

              490       500       510       520       530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
              490       500       510       520       530

>>XP_011538837 (OMIM: 607826) PREDICTED: adenosylhomocys  (505 aa)
 initn: 3264 init1: 3264 opt: 3265  Z-score: 3710.1  bits: 696.1 E(85289): 6.5e-200
Smith-Waterman score: 3265; 98.2% identity (98.6% similar) in 501 aa overlap (1-497:1-501)

               10        20        30        40        50        60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
              430       440       450       460       470       480

              490           500       510       520       530
pF1KE0 VYLLPKKMDE----YVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::     : . .::                                 
XP_011 VYLLPKKMDTNGPYYQGPVHLNHTL                             
              490       500                                  

>>NP_001229603 (OMIM: 607826) adenosylhomocysteinase 2 i  (483 aa)
 initn: 3238 init1: 3238 opt: 3238  Z-score: 3679.7  bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)

        20        30        40        50        60        70       
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                     ::::::::::::::::::::::::::::::
NP_001                               MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                             10        20        30

        80        90       100       110       120       130       
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
               40        50        60        70        80        90

       140       150       160       170       180       190       
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
              100       110       120       130       140       150

       200       210       220       230       240       250       
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
              160       170       180       190       200       210

       260       270       280       290       300       310       
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
              220       230       240       250       260       270

       320       330       340       350       360       370       
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
              280       290       300       310       320       330

       380       390       400       410       420       430       
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
              340       350       360       370       380       390

       440       450       460       470       480       490       
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
              400       410       420       430       440       450

       500       510       520       530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
              460       470       480   

>>NP_001229605 (OMIM: 607826) adenosylhomocysteinase 2 i  (483 aa)
 initn: 3238 init1: 3238 opt: 3238  Z-score: 3679.7  bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)

        20        30        40        50        60        70       
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                     ::::::::::::::::::::::::::::::
NP_001                               MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                             10        20        30

        80        90       100       110       120       130       
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
               40        50        60        70        80        90

       140       150       160       170       180       190       
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
              100       110       120       130       140       150

       200       210       220       230       240       250       
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
              160       170       180       190       200       210

       260       270       280       290       300       310       
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
              220       230       240       250       260       270

       320       330       340       350       360       370       
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
              280       290       300       310       320       330

       380       390       400       410       420       430       
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
              340       350       360       370       380       390

       440       450       460       470       480       490       
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
              400       410       420       430       440       450

       500       510       520       530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
              460       470       480   

>>NP_001229602 (OMIM: 607826) adenosylhomocysteinase 2 i  (483 aa)
 initn: 3238 init1: 3238 opt: 3238  Z-score: 3679.7  bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)

        20        30        40        50        60        70       
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                     ::::::::::::::::::::::::::::::
NP_001                               MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                             10        20        30

        80        90       100       110       120       130       
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
               40        50        60        70        80        90

       140       150       160       170       180       190       
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
              100       110       120       130       140       150

       200       210       220       230       240       250       
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
              160       170       180       190       200       210

       260       270       280       290       300       310       
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
              220       230       240       250       260       270

       320       330       340       350       360       370       
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
              280       290       300       310       320       330

       380       390       400       410       420       430       
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
              340       350       360       370       380       390

       440       450       460       470       480       490       
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
              400       410       420       430       440       450

       500       510       520       530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
              460       470       480   

>>NP_001229604 (OMIM: 607826) adenosylhomocysteinase 2 i  (483 aa)
 initn: 3238 init1: 3238 opt: 3238  Z-score: 3679.7  bits: 690.4 E(85289): 3.2e-198
Smith-Waterman score: 3238; 100.0% identity (100.0% similar) in 483 aa overlap (48-530:1-483)

        20        30        40        50        60        70       
pF1KE0 QAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                     ::::::::::::::::::::::::::::::
NP_001                               MQEFTKFPTKTGRRSLSRSISQSSTDSYSS
                                             10        20        30

        80        90       100       110       120       130       
pF1KE0 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRA
               40        50        60        70        80        90

       140       150       160       170       180       190       
pF1KE0 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAV
              100       110       120       130       140       150

       200       210       220       230       240       250       
pF1KE0 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVT
              160       170       180       190       200       210

       260       270       280       290       300       310       
pF1KE0 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVC
              220       230       240       250       260       270

       320       330       340       350       360       370       
pF1KE0 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNK
              280       290       300       310       320       330

       380       390       400       410       420       430       
pF1KE0 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLL
              340       350       360       370       380       390

       440       450       460       470       480       490       
pF1KE0 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHL
              400       410       420       430       440       450

       500       510       520       530
pF1KE0 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::::::::::::::::::::::::
NP_001 PSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
              460       470       480   

>>NP_056143 (OMIM: 616520) adenosylhomocysteinase 3 isof  (611 aa)
 initn: 3114 init1: 3114 opt: 3129  Z-score: 3554.3  bits: 667.5 E(85289): 3.1e-191
Smith-Waterman score: 3129; 92.0% identity (97.4% similar) in 501 aa overlap (33-530:111-611)

             10        20        30           40        50         
pF1KE0 MPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAP---KKQIQFADDMQEFTKFPTKTG
                                     :::.::   ::::::::. :::.: ::: :
NP_056 PQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKQIQFADQKQEFNKRPTKIG
               90       100       110       120       130       140

      60        70        80        90       100       110         
pF1KE0 RRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRRE
       :::::::::::::::::::::::::::::.:::.::: ::::::.:::::::::::::::
NP_056 RRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRRE
              150       160       170       180       190       200

     120       130       140       150       160       170         
pF1KE0 IEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNI
       ::::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.::::
NP_056 IEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNI
              210       220       230       240       250       260

     180       190       200       210       220       230         
pF1KE0 YSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYK
       ::: :::::::::.:  :::::::::::::::::::::..::: :::::::::::::.::
NP_056 YSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYK
              270       280       290       300       310       320

     240       250       260       270       280       290         
pF1KE0 KYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILD
       ::::.::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILD
              330       340       350       360       370       380

     300       310       320       330       340       350         
pF1KE0 GLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVK
       :::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.::
NP_056 GLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVK
              390       400       410       420       430       440

     360       370       380       390       400       410         
pF1KE0 LNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERV
       :::::::::.:::::::::::::::::::::::::::::::::::::.::::::::::::
NP_056 LNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERV
              450       460       470       480       490       500

     420       430       440       450       460       470         
pF1KE0 RSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQ
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_056 RSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQ
              510       520       530       540       550       560

     480       490       500       510       520       530
pF1KE0 DVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_056 DVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
              570       580       590       600       610 

>>NP_001124192 (OMIM: 616520) adenosylhomocysteinase 3 i  (610 aa)
 initn: 3103 init1: 3103 opt: 3123  Z-score: 3547.5  bits: 666.3 E(85289): 7.4e-191
Smith-Waterman score: 3123; 91.8% identity (97.6% similar) in 500 aa overlap (33-530:111-610)

             10        20        30          40        50        60
pF1KE0 MPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPK--KQIQFADDMQEFTKFPTKTGR
                                     :::.::.  :.:::::. :::.: ::: ::
NP_001 PQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGR
               90       100       110       120       130       140

               70        80        90       100       110       120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
       ::::::::::::::::::::::::::::.:::.::: ::::::.::::::::::::::::
NP_001 RSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREI
              150       160       170       180       190       200

              130       140       150       160       170       180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
       :::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.:::::
NP_001 EIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIY
              210       220       230       240       250       260

              190       200       210       220       230       240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
       :: :::::::::.:  :::::::::::::::::::::..::: :::::::::::::.:::
NP_001 STLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKK
              270       280       290       300       310       320

              250       260       270       280       290       300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
       :::.::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
              330       340       350       360       370       380

              310       320       330       340       350       360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
       ::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.:::
NP_001 LKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKL
              390       400       410       420       430       440

              370       380       390       400       410       420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
       ::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 NEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVR
              450       460       470       480       490       500

              430       440       450       460       470       480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
              510       520       530       540       550       560

              490       500       510       520       530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       ::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_001 VYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
              570       580       590       600       610

>>NP_001124194 (OMIM: 616520) adenosylhomocysteinase 3 i  (508 aa)
 initn: 3107 init1: 3107 opt: 3110  Z-score: 3534.0  bits: 663.5 E(85289): 4.2e-190
Smith-Waterman score: 3110; 90.5% identity (97.2% similar) in 504 aa overlap (27-530:5-508)

               10        20        30        40        50        60
pF1KE0 MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
                                 : ..... ... : ::::::. :::.: ::: ::
NP_001                       MLGSKKKYIVNGNSGIKAQIQFADQKQEFNKRPTKIGR
                                     10        20        30        

               70        80        90       100       110       120
pF1KE0 RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
       ::::::::::::::::::::::::::::.:::.::: ::::::.::::::::::::::::
NP_001 RSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREI
       40        50        60        70        80        90        

              130       140       150       160       170       180
pF1KE0 EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
       :::::.: ::..:::::::::::::::::::::::::::::.::: ::::::::.:::::
NP_001 EIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIY
      100       110       120       130       140       150        

              190       200       210       220       230       240
pF1KE0 STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
       :: :::::::::.:  :::::::::::::::::::::..::: :::::::::::::.:::
NP_001 STLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKK
      160       170       180       190       200       210        

              250       260       270       280       290       300
pF1KE0 YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
       :::.::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
      220       230       240       250       260       270        

              310       320       330       340       350       360
pF1KE0 LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
       ::::::.:::::::::::::::::::::::::.:.:::.:::::::::::::::::.:::
NP_001 LKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKL
      280       290       300       310       320       330        

              370       380       390       400       410       420
pF1KE0 NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
       ::::::::.:::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 NEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVR
      340       350       360       370       380       390        

              430       440       450       460       470       480
pF1KE0 SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
      400       410       420       430       440       450        

              490       500       510       520       530
pF1KE0 VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       ::::::::::::::::::.::::::::::.::::::::::::::::::::
NP_001 VYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
      460       470       480       490       500        

>>NP_001124195 (OMIM: 616520) adenosylhomocysteinase 3 i  (508 aa)
 initn: 3103 init1: 3103 opt: 3103  Z-score: 3526.1  bits: 662.1 E(85289): 1.2e-189
Smith-Waterman score: 3103; 92.1% identity (97.8% similar) in 493 aa overlap (38-530:16-508)

        10        20        30        40        50        60       
pF1KE0 PLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSI
                                     :. .:::::. :::.: ::: :::::::::
NP_001                MEKWDGNEGTSAFHMPEWMIQFADQKQEFNKRPTKIGRRSLSRSI
                              10        20        30        40     

        70        80        90       100       110       120       
pF1KE0 SQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDM
       :::::::::::::::::::::.:::.::: ::::::.:::::::::::::::::::::.:
NP_001 SQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEM
          50        60        70        80        90       100     

       130       140       150       160       170       180       
pF1KE0 SALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIYSTQNEVA
        ::..:::::::::::::::::::::::::::::.::: ::::::::.::::::: ::::
NP_001 PALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVA
         110       120       130       140       150       160     

       190       200       210       220       230       240       
pF1KE0 AALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKK
       :::::.:  :::::::::::::::::::::..::: :::::::::::::.::::::.:::
NP_001 AALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKK
         170       180       190       200       210       220     

       250       260       270       280       290       300       
pF1KE0 IRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDV
       :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 IKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDM
         230       240       250       260       270       280     

       310       320       330       340       350       360       
pF1KE0 MFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQV
       :::::::::::::::::::::::::.:.:::.:::::::::::::::::.::::::::::
NP_001 MFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQV
         290       300       310       320       330       340     

       370       380       390       400       410       420       
pF1KE0 DVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVI
       :.:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 DIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVI
         350       360       370       380       390       400     

       430       440       450       460       470       480       
pF1KE0 WPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKK
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKK
         410       420       430       440       450       460     

       490       500       510       520       530
pF1KE0 MDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
       :::::::::::.::::::::::.::::::::::::::::::::
NP_001 MDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
         470       480       490       500        




530 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:39:14 2016 done: Thu Nov  3 14:39:15 2016
 Total Scan time:  8.120 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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