Result of FASTA (omim) for pF1KB9989
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9989, 579 aa
  1>>>pF1KB9989 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6821+/-0.000417; mu= 13.7210+/- 0.026
 mean_var=173.0127+/-37.303, 0's: 0 Z-trim(115.7): 286  B-trim: 1223 in 1/53
 Lambda= 0.097507
 statistics sampled from 25958 (26311) to 25958 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.308), width:  16
 Scan time:  9.390

The best scores are:                                      opt bits E(85289)
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 3961 570.2 6.5e-162
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  463 77.8 6.1e-14
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  463 77.8 6.1e-14
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  463 77.8 6.1e-14
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357)  411 70.5   1e-11
NP_060444 (OMIM: 610767,611081) autophagy-related  ( 588)  316 57.4 1.5e-07
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504)  310 56.5 2.4e-07
NP_942593 (OMIM: 610767,611081) autophagy-related  ( 444)  305 55.7 3.6e-07
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463)  305 55.8 3.7e-07
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480)  305 55.8 3.8e-07
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491)  305 55.8 3.9e-07
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523)  305 55.8   4e-07
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540)  305 55.8 4.1e-07
NP_110430 (OMIM: 610767,611081) autophagy-related  ( 607)  305 55.9 4.4e-07
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624)  305 55.9 4.5e-07
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478)  298 54.8 7.5e-07
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  300 55.2 7.6e-07
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  300 55.2 7.6e-07
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  300 55.2 7.6e-07
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  300 55.2 7.6e-07
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  300 55.3 7.7e-07
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  300 55.3 7.7e-07
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  300 55.3 7.7e-07
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  300 55.3 7.8e-07
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  300 55.3 7.8e-07
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  300 55.3 7.8e-07
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  300 55.3 7.8e-07
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390)  294 54.1 9.7e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  291 53.6 1.2e-06
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  291 53.6 1.2e-06
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  291 53.6 1.2e-06
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323)  291 53.6 1.2e-06
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512)  294 54.3 1.2e-06
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512)  294 54.3 1.2e-06
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528)  294 54.3 1.2e-06
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528)  294 54.3 1.2e-06
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537)  294 54.3 1.2e-06
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577)  294 54.3 1.3e-06
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600)  294 54.4 1.3e-06
NP_078808 (OMIM: 612173) sperm-associated antigen  ( 631)  294 54.4 1.3e-06
XP_016877356 (OMIM: 604447) PREDICTED: guanine nuc ( 212)  286 52.7 1.4e-06
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301)  286 52.9 1.8e-06
XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353)  286 53.0   2e-06
NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353)  286 53.0   2e-06
NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395)  286 53.0 2.1e-06
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577)  286 53.2 2.7e-06
XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582)  286 53.2 2.8e-06
XP_011510117 (OMIM: 612173) PREDICTED: sperm-assoc ( 592)  286 53.2 2.8e-06
XP_011510118 (OMIM: 612173) PREDICTED: sperm-assoc ( 592)  286 53.2 2.8e-06
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300)  280 52.0 3.2e-06


>>NP_056975 (OMIM: 605585) pre-mRNA-processing factor 17  (579 aa)
 initn: 3961 init1: 3961 opt: 3961  Z-score: 3027.8  bits: 570.2 E(85289): 6.5e-162
Smith-Waterman score: 3961; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)

               10        20        30        40        50        60
pF1KB9 MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 AVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 NDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 FKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 MDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTT
              490       500       510       520       530       540

              550       560       570         
pF1KB9 KLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
       :::::::::::::::::::::::::::::::::::::::
NP_056 KLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
              550       560       570         

>>NP_438172 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 552 init1: 164 opt: 463  Z-score: 371.2  bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)

          260       270       280       290       300       310    
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
                                     .::::.::.:.. : .:. : : : :  ::
NP_438 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
              20        30        40        50         60        70

          320       330       340       350       360       370    
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
       .: .: . .  .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
NP_438 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
                80        90       100       110       120         

           380       390       400       410       420       430   
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
          .: .:::   ..::.:.:  :...  ::...:. ..    :   :... :  ..  .
NP_438 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
     130          140       150       160       170       180      

           440       450       460       470       480       490   
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
       ::.: :   :.:.      .: . . .   .  : .:::::..   ..:: . ..   . 
NP_438 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
        190       200       210       220       230       240      

           500       510        520       530       540       550  
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
        . .  : . ::    :   ..::    ....::. .. . ::. .: .. .....:  :
NP_438 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
           250       260       270       280       290       300   

            560       570               
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD   
        :... :: :.  .:. .    :  ::::    
NP_438 VISTACHPTEN--IIASAALENDKTIKLWKSDC
           310         320       330    

>>NP_060058 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 552 init1: 164 opt: 463  Z-score: 371.2  bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)

          260       270       280       290       300       310    
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
                                     .::::.::.:.. : .:. : : : :  ::
NP_060 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
              20        30        40        50         60        70

          320       330       340       350       360       370    
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
       .: .: . .  .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
NP_060 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
                80        90       100       110       120         

           380       390       400       410       420       430   
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
          .: .:::   ..::.:.:  :...  ::...:. ..    :   :... :  ..  .
NP_060 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
     130          140       150       160       170       180      

           440       450       460       470       480       490   
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
       ::.: :   :.:.      .: . . .   .  : .:::::..   ..:: . ..   . 
NP_060 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
        190       200       210       220       230       240      

           500       510        520       530       540       550  
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
        . .  : . ::    :   ..::    ....::. .. . ::. .: .. .....:  :
NP_060 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
           250       260       270       280       290       300   

            560       570               
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD   
        :... :: :.  .:. .    :  ::::    
NP_060 VISTACHPTEN--IIASAALENDKTIKLWKSDC
           310         320       330    

>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta  (334 aa)
 initn: 552 init1: 164 opt: 463  Z-score: 371.2  bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)

          260       270       280       290       300       310    
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
                                     .::::.::.:.. : .:. : : : :  ::
XP_005 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
              20        30        40        50         60        70

          320       330       340       350       360       370    
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
       .: .: . .  .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
XP_005 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
                80        90       100       110       120         

           380       390       400       410       420       430   
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
          .: .:::   ..::.:.:  :...  ::...:. ..    :   :... :  ..  .
XP_005 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
     130          140       150       160       170       180      

           440       450       460       470       480       490   
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
       ::.: :   :.:.      .: . . .   .  : .:::::..   ..:: . ..   . 
XP_005 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
        190       200       210       220       230       240      

           500       510        520       530       540       550  
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
        . .  : . ::    :   ..::    ....::. .. . ::. .: .. .....:  :
XP_005 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
           250       260       270       280       290       300   

            560       570               
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD   
        :... :: :.  .:. .    :  ::::    
XP_005 VISTACHPTEN--IIASAALENDKTIKLWKSDC
           310         320       330    

>>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr  (357 aa)
 initn: 272 init1: 166 opt: 411  Z-score: 331.3  bits: 70.5 E(85289): 1e-11
Smith-Waterman score: 411; 26.4% identity (58.1% similar) in 296 aa overlap (271-562:49-339)

              250       260       270       280       290       300
pF1KB9 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
                                     : .:   .  : . :::   :   .. : .
NP_004 RQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHP-N
       20        30        40        50        60        70        

              310       320       330       340       350       360
pF1KB9 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
       :  : : ..:  : ::.:::.     :. ::: :: .. .:: :....::. :. . .::
NP_004 GSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWD
        80        90       100       110       120       130       

              370       380       390       400       410       420
pF1KB9 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
       .:::. ..:. .. . .  .  : .   .:  .: .:  .  ::::.   .: . ..   
NP_004 SETGERVKRLKGH-TSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTYQ
       140       150        160       170       180       190      

              430       440       450       460       470       480
pF1KB9 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
       : ...: : . ...: . :....::.      . :  .    :. ...:: .:..:  ..
NP_004 VLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLTYTMRGHADSVTGLSLSSEGSYLLSNA
         200       210       220        230       240       250    

              490         500         510       520       530      
pF1KB9 MDNQILIFGAQNRFRLNKK--KIFKG--HMVAGYACQVDFSPDMSYVISGDGNGKLNIWD
       ::: . .. ..  :  ...  :::.:  :       . ..::: : . .:...  . .::
NP_004 MDNTVRVWDVRP-FAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWD
          260        270       280       290       300       310   

        540       550       560       570          
pF1KB9 WKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD 
         . ..  .. .:      ...:: :                  
NP_004 TTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ
           320       330       340       350       

>>NP_060444 (OMIM: 610767,611081) autophagy-related prot  (588 aa)
 initn: 283 init1: 106 opt: 316  Z-score: 256.6  bits: 57.4 E(85289): 1.5e-07
Smith-Waterman score: 342; 26.9% identity (54.7% similar) in 402 aa overlap (201-578:209-585)

              180       190       200       210       220       230
pF1KB9 GQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQE
                                     .:::  . . . :::: : .::.    .:.
NP_060 KLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAE-AAKEPLPVEQD
      180       190       200       210       220        230       

                        240       250       260       270          
pF1KB9 EE----------KPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--EKCYLPK
       ..          .  : . .  ...    .. : . .:::   :. .: :   ..  .: 
NP_060 DDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQD---NV-DTHPGSGKEVRVPA
       240       250       260       270           280       290   

      280       290       300       310       320        330       
pF1KB9 KQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRD
         . :...:   :.::.. : : .:: . .:: ..:::::.::.  .. .. : . .. .
NP_060 TALCVFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITS
           300       310        320       330       340       350  

       340       350       360       370         380       390     
pF1KB9 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGM
       : :..::. .:.:. :   ..: ..  .    .:..  ::   .::  :. .   .:.: 
NP_060 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGS
            360       370       380       390        400           

         400       410       420        430       440       450    
pF1KB9 SDKKIVQWDIRSGEIVQEYDRHLGA-VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFK
        :. .  ::.::   ..      :.  : :: ...    .:   ::..: :  ::  .  
NP_060 HDRTLKLWDLRSKVCIKTV--FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESI
      410       420         430       440         450         460  

          460       470        480       490        500       510  
pF1KB9 YIAEPSMHSMPAVTLSPN-GKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYAC
             . .. :. :.:.  . :.: : :. . ..     .: :  :. :..    :. :
NP_060 VREMELLGKITALDLNPERTELLSC-SRDDLLKVID----LRTNAIKQTFSA---PGFKC
            470       480        490           500          510    

                 520       530       540       550        560      
pF1KB9 QVD-----FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKV
         :     :::: ::: .:...:.: ::.  : :. . .. . .  :.:: : :   :.:
NP_060 GSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHV
          520       530       540       550       560        570   

        570           
pF1KB9 ITCGWDGLIKLWD  
       ..        ::   
NP_060 VSVDKGCKAVLWAQY
           580        

>>NP_055317 (OMIM: 608330) pre-mRNA-processing factor 19  (504 aa)
 initn: 234 init1: 209 opt: 310  Z-score: 252.8  bits: 56.5 E(85289): 2.4e-07
Smith-Waterman score: 324; 25.2% identity (56.6% similar) in 290 aa overlap (213-487:177-461)

            190       200       210       220          230         
pF1KB9 ENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGK---QEEEKPGEEKT
                                     : .   .:..:.:.::   .:  :: : . 
NP_055 PSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSK
        150       160       170       180       190       200      

     240       250             260       270       280          290
pF1KB9 ILHVKEMYDYQGRSYLHI------PQDVGVNLRSTMPPEKCYLPKKQIHVWS---GHTKG
         .:      .. :   :      :.:..  : .    .   . :.. .. .   :::: 
NP_055 YRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKK
        210       220       230       240       250       260      

              300       310       320       330       340       350
pF1KB9 VSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSA
       :..: . : :  :..: : :  :..: : .   :...  .: .::  . ....:  .::.
NP_055 VTSVVFHP-SQDLVFSASPDATIRIWSVPNAS-CVQVVRAHESAVTGLSLHATGDYLLSS
        270        280       290        300       310       320    

              360       370          380       390       400       
pF1KB9 AYDRYLKLWDTETGQCISRFTNRKVP---YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRS
       . :.:  . : .::. ... :..       :..:.::     .: .:  :..:  ::.. 
NP_055 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD---GLIFGTGTMDSQIKIWDLKE
          330       340       350       360          370       380 

       410       420       430       440       450       460       
pF1KB9 GEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAV
          : ..  : : ...:.: ...  .....::.:...:.     .:: .   .   . ..
NP_055 RTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSL
             390       400       410       420       430       440 

       470       480       490       500       510       520       
pF1KB9 TLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGD
        .. .: .::  . : :: :                                        
NP_055 IFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKF
             450       460       470       480       490       500 

>>NP_942593 (OMIM: 610767,611081) autophagy-related prot  (444 aa)
 initn: 257 init1: 106 opt: 305  Z-score: 249.6  bits: 55.7 E(85289): 3.6e-07
Smith-Waterman score: 334; 26.6% identity (55.2% similar) in 395 aa overlap (202-578:77-441)

             180       190       200       210           220       
pF1KB9 QKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEE----EQKELDEITAKRQKKG
                                     .:..:. ..:    :: .  :. .  . . 
NP_942 DLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPVEQDDDIEVIVD-ETSD
         50        60        70        80        90       100      

       230       240       250       260       270         280     
pF1KB9 KQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--EKCYLPKKQIHVWS
       . :: .:     .  ...    .. : . .:::   :. .: :   ..  .:   . :..
NP_942 HTEETSP-----VRAISRAATRRSVSSFPVPQD---NV-DTHPGSGKEVRVPATALCVFD
         110            120       130           140       150      

         290       300       310       320        330       340    
pF1KB9 GHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRDICFNTAG
       .:   :.::.. : : .:: . .:: ..:::::.::.  .. .. : . .. .: :..::
NP_942 AHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG
        160       170        180       190       200       210     

          350       360       370         380       390       400  
pF1KB9 TQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGMSDKKIVQ
       . .:.:. :   ..: ..  .    .:..  ::   .::  :. .   .:.:  :. .  
NP_942 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGSHDRTLKL
         220       230       240        250          260       270 

            410       420        430       440       450       460 
pF1KB9 WDIRSGEIVQEYDRHLGA-VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSM
       ::.::   ..      :.  : :: ...    .:   ::..: :  ::  .        .
NP_942 WDLRSKVCIKTV--FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESIVREMELL
             280         290         300       310         320     

             470        480       490        500       510         
pF1KB9 HSMPAVTLSPN-GKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYACQVD----
        .. :. :.:.  . :.: : :. . ..     .: :  :. :..    :. :  :    
NP_942 GKITALDLNPERTELLSC-SRDDLLKVID----LRTNAIKQTFSA---PGFKCGSDWTRV
         330       340        350           360          370       

          520       530       540       550        560       570   
pF1KB9 -FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKVITCGWDG
        :::: ::: .:...:.: ::.  : :. . .. . .  :.:: : :   :.:..     
NP_942 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHVVSVDKGC
       380       390       400       410       420        430      

               
pF1KB9 LIKLWD  
          ::   
NP_942 KAVLWAQY
        440    

>>XP_005246143 (OMIM: 610767,611081) PREDICTED: autophag  (463 aa)
 initn: 257 init1: 106 opt: 305  Z-score: 249.4  bits: 55.8 E(85289): 3.7e-07
Smith-Waterman score: 351; 24.8% identity (53.3% similar) in 467 aa overlap (128-578:28-460)

       100       110       120       130           140       150   
pF1KB9 PFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFAT----YGYALDPSLDNHQVSAKYI
                                     ::..:      :.  :. : : :.: :. .
XP_005    MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKS-DLHSVLAQKL
                  10        20        30        40         50      

           160       170       180       190       200       210   
pF1KB9 GSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQ
           .:::..  .  :  ..... .:.. :     .     :  .  : . ..  . .. 
XP_005 ----QAEKHDVPNRHEIRRRQARLQKELAEAAKEPL-----PVEQDDDIEVIVDETSDHT
             60        70        80             90       100       

           220       230       240       250       260       270   
pF1KB9 KELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--
       .: . . :  .   :.  .  :    .  . ...  .. : . .:::   :. .: :   
XP_005 EETSPVRAISRAATKRLSQPAG--GLLDSITNIFGRRSVSSFPVPQD---NV-DTHPGSG
       110       120         130       140       150           160 

             280       290       300       310       320        330
pF1KB9 EKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIG
       ..  .:   . :...:   :.::.. : : .:: . .:: ..:::::.::.  .. .. :
XP_005 KEVRVPATALCVFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSG
             170       180       190        200       210       220

              340       350       360       370         380        
pF1KB9 HSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQ
        . .. .: :..::. .:.:. :   ..: ..  .    .:..  ::   .::  :. . 
XP_005 SNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR-
              230       240       250       260        270         

      390       400       410       420       430       440        
pF1KB9 NLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWD
         .:.:  :. .  ::.::   ..      .. : :: ...    .:   ::..:   ::
XP_005 --IVSGSHDRTLKLWDLRSKVCIKTV-FAGSSCNDIVCTEQC--VMSGHFDKKIRF--WD
        280       290       300        310         320         330 

      450       460       470       480       490        500       
pF1KB9 IPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMV
       :  .        . .. :. :.:.   :   : :. . ..     .: :  :. :..   
XP_005 IRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID----LRTNAIKQTFSA---
             340       350       360       370           380       

       510            520       530       540       550        560 
pF1KB9 AGYACQVD-----FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPH
        :. :  :     :::: ::: .:...:.: ::.  : :. . .. . .  :.:: : : 
XP_005 PGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS
          390       400       410       420       430       440    

             570           
pF1KB9 ETSKVITCGWDGLIKLWD  
         :.:..        ::   
XP_005 -GSHVVSVDKGCKAVLWAQY
           450       460   

>>XP_005246141 (OMIM: 610767,611081) PREDICTED: autophag  (480 aa)
 initn: 257 init1: 106 opt: 305  Z-score: 249.3  bits: 55.8 E(85289): 3.8e-07
Smith-Waterman score: 330; 27.7% identity (55.1% similar) in 336 aa overlap (253-578:162-477)

            230       240       250       260       270       280  
pF1KB9 RQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIH
                                     : . .::: .:. .     :   .:   . 
XP_005 LDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQD-NVDTHPGSGKE-VRVPATALC
             140       150       160        170       180          

            290       300       310       320        330       340 
pF1KB9 VWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRDICFN
       :...:   :.::.. : : .:: . .:: ..:::::.::.  .. .. : . .. .: :.
XP_005 VFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFD
     190       200        210       220       230       240        

             350       360       370         380       390         
pF1KB9 TAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGMSDKK
       .::. .:.:. :   ..: ..  .    .:..  ::   .::  :. .   .:.:  :. 
XP_005 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGSHDRT
      250       260       270       280        290          300    

     400       410       420       430       440       450         
pF1KB9 IVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEP
       .  ::.::   ..      .. : :: ...    .:   ::..: :  ::  .       
XP_005 LKLWDLRSKVCIKTV-FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESIVREME
          310        320       330         340         350         

     460       470       480       490        500       510        
pF1KB9 SMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYACQVD---
        . .. :. :.:.   :   : :. . ..     .: :  :. :.   . :. :  :   
XP_005 LLGKITALDLNPERTELLSCSRDDLLKVID----LRTNAIKQTFS---APGFKCGSDWTR
     360       370       380           390       400          410  

           520       530       540       550        560       570  
pF1KB9 --FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKVITCGWD
         :::: ::: .:...:.: ::.  : :. . .. . .  :.:: : :   :.:..    
XP_005 VVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHVVSVDKG
            420       430       440       450       460        470 

                
pF1KB9 GLIKLWD  
           ::   
XP_005 CKAVLWAQY
             480




579 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:49:48 2016 done: Sat Nov  5 18:49:50 2016
 Total Scan time:  9.390 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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