Result of FASTA (ccds) for pF1KB6242
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6242, 687 aa
  1>>>pF1KB6242 687 - 687 aa - 687 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4914+/-0.00106; mu= 15.2615+/- 0.065
 mean_var=114.6137+/-22.350, 0's: 0 Z-trim(107.5): 75  B-trim: 0 in 0/51
 Lambda= 0.119800
 statistics sampled from 9514 (9589) to 9514 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.295), width:  16
 Scan time:  3.940

The best scores are:                                      opt bits E(32554)
CCDS56372.1 PDE4D gene_id:5144|Hs108|chr5          ( 687) 4507 790.4       0
CCDS56371.1 PDE4D gene_id:5144|Hs108|chr5          ( 679) 4337 761.1       0
CCDS47213.1 PDE4D gene_id:5144|Hs108|chr5          ( 809) 4315 757.3 1.9e-218
CCDS56373.1 PDE4D gene_id:5144|Hs108|chr5          ( 745) 4313 756.9 2.3e-218
CCDS54859.1 PDE4D gene_id:5144|Hs108|chr5          ( 748) 4309 756.2 3.7e-218
CCDS54858.1 PDE4D gene_id:5144|Hs108|chr5          ( 673) 4304 755.4 6.2e-218
CCDS56370.1 PDE4D gene_id:5144|Hs108|chr5          ( 507) 3328 586.6  3e-167
CCDS56369.1 PDE4D gene_id:5144|Hs108|chr5          ( 518) 3304 582.4 5.4e-166
CCDS30742.1 PDE4B gene_id:5142|Hs108|chr1          ( 721) 3239 571.3 1.7e-162
CCDS632.1 PDE4B gene_id:5142|Hs108|chr1            ( 736) 3225 568.9 9.2e-162
CCDS12373.1 PDE4C gene_id:5143|Hs108|chr19         ( 712) 3052 539.0  9e-153
CCDS42523.1 PDE4C gene_id:5143|Hs108|chr19         ( 680) 3045 537.8  2e-152
CCDS46016.1 PDE4C gene_id:5143|Hs108|chr19         ( 606) 2926 517.2 2.8e-146
CCDS30743.1 PDE4B gene_id:5142|Hs108|chr1          ( 564) 2720 481.5 1.4e-135
CCDS72802.1 PDE4B gene_id:5142|Hs108|chr1          ( 503) 2506 444.5 1.7e-124
CCDS12238.1 PDE4A gene_id:5141|Hs108|chr19         ( 647) 2207 392.9 7.7e-109
CCDS45963.1 PDE4A gene_id:5141|Hs108|chr19         ( 825) 2203 392.3 1.5e-108
CCDS45962.1 PDE4A gene_id:5141|Hs108|chr19         ( 860) 2203 392.3 1.5e-108
CCDS58649.1 PDE4A gene_id:5141|Hs108|chr19         ( 864) 2203 392.3 1.5e-108
CCDS45961.1 PDE4A gene_id:5141|Hs108|chr19         ( 886) 2203 392.3 1.6e-108
CCDS5175.1 PDE7B gene_id:27115|Hs108|chr6          ( 450)  782 146.5   8e-35
CCDS34901.1 PDE7A gene_id:5150|Hs108|chr8          ( 456)  738 138.9 1.6e-32
CCDS56538.1 PDE7A gene_id:5150|Hs108|chr8          ( 482)  736 138.6 2.1e-32
CCDS34190.1 PDE8B gene_id:8622|Hs108|chr5          ( 830)  618 118.4 4.4e-26
CCDS34192.1 PDE8B gene_id:8622|Hs108|chr5          ( 788)  608 116.6 1.4e-25
CCDS34191.1 PDE8B gene_id:8622|Hs108|chr5          ( 838)  608 116.6 1.5e-25
CCDS34193.1 PDE8B gene_id:8622|Hs108|chr5          ( 865)  608 116.6 1.5e-25
CCDS4037.1 PDE8B gene_id:8622|Hs108|chr5           ( 885)  608 116.6 1.5e-25
CCDS42944.1 PDE9A gene_id:5152|Hs108|chr21         ( 459)  599 114.9 2.7e-25
CCDS74612.1 PDE1A gene_id:5136|Hs108|chr2          ( 501)  594 114.0 5.2e-25
CCDS42947.1 PDE9A gene_id:5152|Hs108|chr21         ( 433)  593 113.8 5.3e-25
CCDS33571.1 PDE9A gene_id:5152|Hs108|chr21         ( 465)  593 113.8 5.6e-25
CCDS42946.1 PDE9A gene_id:5152|Hs108|chr21         ( 466)  593 113.8 5.6e-25
CCDS33570.1 PDE9A gene_id:5152|Hs108|chr21         ( 491)  593 113.9 5.8e-25
CCDS42943.1 PDE9A gene_id:5152|Hs108|chr21         ( 492)  593 113.9 5.8e-25
CCDS42941.1 PDE9A gene_id:5152|Hs108|chr21         ( 507)  593 113.9   6e-25
CCDS42945.1 PDE9A gene_id:5152|Hs108|chr21         ( 526)  593 113.9 6.1e-25
CCDS33568.1 PDE9A gene_id:5152|Hs108|chr21         ( 533)  593 113.9 6.2e-25
CCDS33567.1 PDE9A gene_id:5152|Hs108|chr21         ( 540)  593 113.9 6.3e-25
CCDS42942.1 PDE9A gene_id:5152|Hs108|chr21         ( 552)  593 113.9 6.4e-25
CCDS33569.1 PDE9A gene_id:5152|Hs108|chr21         ( 567)  593 113.9 6.5e-25
CCDS13690.1 PDE9A gene_id:5152|Hs108|chr21         ( 593)  593 113.9 6.7e-25
CCDS33344.1 PDE1A gene_id:5136|Hs108|chr2          ( 535)  591 113.5 7.9e-25
CCDS2285.1 PDE1A gene_id:5136|Hs108|chr2           ( 545)  591 113.5   8e-25
CCDS58741.1 PDE1A gene_id:5136|Hs108|chr2          ( 519)  587 112.8 1.2e-24
CCDS5437.1 PDE1C gene_id:5137|Hs108|chr7           ( 634)  554 107.2 7.6e-23
CCDS55099.1 PDE1C gene_id:5137|Hs108|chr7          ( 709)  554 107.2 8.3e-23
CCDS55100.1 PDE1C gene_id:5137|Hs108|chr7          ( 769)  554 107.3 8.8e-23
CCDS8882.1 PDE1B gene_id:5153|Hs108|chr12          ( 536)  526 102.3 1.9e-21
CCDS4299.1 PDE6A gene_id:5145|Hs108|chr5           ( 860)  522 101.8 4.5e-21


>>CCDS56372.1 PDE4D gene_id:5144|Hs108|chr5               (687 aa)
 initn: 4507 init1: 4507 opt: 4507  Z-score: 4215.5  bits: 790.4 E(32554):    0
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 687 aa overlap (1-687:1-687)

               10        20        30        40        50        60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
              610       620       630       640       650       660

              670       680       
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::
CCDS56 QVEEEAVGEEEESQPEACVIDDRSPDT
              670       680       

>>CCDS56371.1 PDE4D gene_id:5144|Hs108|chr5               (679 aa)
 initn: 4337 init1: 4337 opt: 4337  Z-score: 4056.8  bits: 761.1 E(32554):    0
Smith-Waterman score: 4337; 98.4% identity (99.1% similar) in 673 aa overlap (15-687:7-679)

               10        20        30        40        50        60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
                     : .:. : :: ...  ::::::::::::::::::::::::::::::
CCDS56         MSIIMKPRSRSTSSLRTAEAVCFDVDNGTSAGRSPLDPMTSPGSGLILQANF
                       10        20        30        40        50  

               70        80        90       100       110       120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
            120       130       140       150       160       170  

              190       200       210       220       230       240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
            180       190       200       210       220       230  

              250       260       270       280       290       300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
            240       250       260       270       280       290  

              310       320       330       340       350       360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
            300       310       320       330       340       350  

              370       380       390       400       410       420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
            360       370       380       390       400       410  

              430       440       450       460       470       480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
            420       430       440       450       460       470  

              490       500       510       520       530       540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
            480       490       500       510       520       530  

              550       560       570       580       590       600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
            540       550       560       570       580       590  

              610       620       630       640       650       660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
            600       610       620       630       640       650  

              670       680       
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::
CCDS56 QVEEEAVGEEEESQPEACVIDDRSPDT
            660       670         

>>CCDS47213.1 PDE4D gene_id:5144|Hs108|chr5               (809 aa)
 initn: 4304 init1: 4304 opt: 4315  Z-score: 4035.2  bits: 757.3 E(32554): 1.9e-218
Smith-Waterman score: 4315; 98.4% identity (99.1% similar) in 672 aa overlap (20-687:138-809)

                          10        20        30            40     
pF1KB6            MAFVWDPLGATVPGPSTRAKSRLRFSKSYS----FDVDNGTSAGRSPLD
                                     :::. . .:..    :::::::::::::::
CCDS47 GYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLD
       110       120       130       140       150       160       

          50        60        70        80        90       100     
pF1KB6 PMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 PMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFA
       170       180       190       200       210       220       

         110       120       130       140       150       160     
pF1KB6 QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 QVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWC
       230       240       250       260       270       280       

         170       180       190       200       210       220     
pF1KB6 LDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIP
       290       300       310       320       330       340       

         230       240       250       260       270       280     
pF1KB6 SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
       350       360       370       380       390       400       

         290       300       310       320       330       340     
pF1KB6 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
       410       420       430       440       450       460       

         350       360       370       380       390       400     
pF1KB6 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
       470       480       490       500       510       520       

         410       420       430       440       450       460     
pF1KB6 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
       530       540       550       560       570       580       

         470       480       490       500       510       520     
pF1KB6 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
       590       600       610       620       630       640       

         530       540       550       560       570       580     
pF1KB6 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
       650       660       670       680       690       700       

         590       600       610       620       630       640     
pF1KB6 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
       710       720       730       740       750       760       

         650       660       670       680       
pF1KB6 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       ::::::::::::::::::::::::::::::::::::::::::
CCDS47 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       770       780       790       800         

>>CCDS56373.1 PDE4D gene_id:5144|Hs108|chr5               (745 aa)
 initn: 4304 init1: 4304 opt: 4313  Z-score: 4033.8  bits: 756.9 E(32554): 2.3e-218
Smith-Waterman score: 4313; 98.1% identity (99.1% similar) in 673 aa overlap (16-687:73-745)

                              10        20        30         40    
pF1KB6                MAFVWDPLGATVPGPSTRAKSRLRFSKSYS-FDVDNGTSAGRSPL
                                     :.   .. ::. ... ::::::::::::::
CCDS56 SKTARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPL
             50        60        70        80        90       100  

           50        60        70        80        90       100    
pF1KB6 DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPF
            110       120       130       140       150       160  

          110       120       130       140       150       160    
pF1KB6 AQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDW
            170       180       190       200       210       220  

          170       180       190       200       210       220    
pF1KB6 CLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 CLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEI
            230       240       250       260       270       280  

          230       240       250       260       270       280    
pF1KB6 PSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGL
            290       300       310       320       330       340  

          290       300       310       320       330       340    
pF1KB6 HVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
            350       360       370       380       390       400  

          350       360       370       380       390       400    
pF1KB6 AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYN
            410       420       430       440       450       460  

          410       420       430       440       450       460    
pF1KB6 DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLK
            470       480       490       500       510       520  

          470       480       490       500       510       520    
pF1KB6 TMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQG
            530       540       550       560       570       580  

          530       540       550       560       570       580    
pF1KB6 DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRE
            590       600       610       620       630       640  

          590       600       610       620       630       640    
pF1KB6 WYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 WYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSK
            650       660       670       680       690       700  

          650       660       670       680       
pF1KB6 TLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::::::::::::::::::
CCDS56 TLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
            710       720       730       740     

>>CCDS54859.1 PDE4D gene_id:5144|Hs108|chr5               (748 aa)
 initn: 4309 init1: 4309 opt: 4309  Z-score: 4030.1  bits: 756.2 E(32554): 3.7e-218
Smith-Waterman score: 4309; 99.4% identity (99.8% similar) in 662 aa overlap (26-687:87-748)

                    10        20        30        40        50     
pF1KB6      MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLI
                                     ..: .:::::::::::::::::::::::::
CCDS54 EQADLKSESENIQRPTSLPLKILPLIAITSAESSGFDVDNGTSAGRSPLDPMTSPGSGLI
         60        70        80        90       100       110      

          60        70        80        90       100       110     
pF1KB6 LQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVR
        120       130       140       150       160       170      

         120       130       140       150       160       170     
pF1KB6 NNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTR
        180       190       200       210       220       230      

         180       190       200       210       220       230     
pF1KB6 HSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKK
        240       250       260       270       280       290      

         240       250       260       270       280       290     
pF1KB6 KRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
        300       310       320       330       340       350      

         300       310       320       330       340       350     
pF1KB6 RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVL
        360       370       380       390       400       410      

         360       370       380       390       400       410     
pF1KB6 LSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLA
        420       430       440       450       460       470      

         420       430       440       450       460       470     
pF1KB6 VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSS
        480       490       500       510       520       530      

         480       490       500       510       520       530     
pF1KB6 GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEIS
        540       550       560       570       580       590      

         540       550       560       570       580       590     
pF1KB6 PMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPS
        600       610       620       630       640       650      

         600       610       620       630       640       650     
pF1KB6 PAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTE
        660       670       680       690       700       710      

         660       670       680       
pF1KB6 IPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       ::::::::::::::::::::::::::::::::
CCDS54 IPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
        720       730       740        

>>CCDS54858.1 PDE4D gene_id:5144|Hs108|chr5               (673 aa)
 initn: 4304 init1: 4304 opt: 4304  Z-score: 4026.0  bits: 755.4 E(32554): 6.2e-218
Smith-Waterman score: 4304; 100.0% identity (100.0% similar) in 657 aa overlap (31-687:17-673)

               10        20        30        40        50        60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
                                     ::::::::::::::::::::::::::::::
CCDS54               MMHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANF
                             10        20        30        40      

               70        80        90       100       110       120
pF1KB6 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
         50        60        70        80        90       100      

              130       140       150       160       170       180
pF1KB6 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KB6 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
        170       180       190       200       210       220      

              250       260       270       280       290       300
pF1KB6 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
        230       240       250       260       270       280      

              310       320       330       340       350       360
pF1KB6 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
        290       300       310       320       330       340      

              370       380       390       400       410       420
pF1KB6 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
        350       360       370       380       390       400      

              430       440       450       460       470       480
pF1KB6 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
        410       420       430       440       450       460      

              490       500       510       520       530       540
pF1KB6 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
        470       480       490       500       510       520      

              550       560       570       580       590       600
pF1KB6 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
        530       540       550       560       570       580      

              610       620       630       640       650       660
pF1KB6 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
        590       600       610       620       630       640      

              670       680       
pF1KB6 QVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::
CCDS54 QVEEEAVGEEEESQPEACVIDDRSPDT
        650       660       670   

>>CCDS56370.1 PDE4D gene_id:5144|Hs108|chr5               (507 aa)
 initn: 3328 init1: 3328 opt: 3328  Z-score: 3116.1  bits: 586.6 E(32554): 3e-167
Smith-Waterman score: 3328; 100.0% identity (100.0% similar) in 507 aa overlap (181-687:1-507)

              160       170       180       190       200       210
pF1KB6 YQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEF
                                     ::::::::::::::::::::::::::::::
CCDS56                               MASNKFKRMLNRELTHLSEMSRSGNQVSEF
                                             10        20        30

              220       230       240       250       260       270
pF1KB6 ISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQED
               40        50        60        70        80        90

              280       290       300       310       320       330
pF1KB6 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLE
              100       110       120       130       140       150

              340       350       360       370       380       390
pF1KB6 DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQ
              160       170       180       190       200       210

              400       410       420       430       440       450
pF1KB6 FLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLA
              220       230       240       250       260       270

              460       470       480       490       500       510
pF1KB6 TDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYR
              280       290       300       310       320       330

              520       530       540       550       560       570
pF1KB6 QWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHP
              340       350       360       370       380       390

              580       590       600       610       620       630
pF1KB6 DAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS
              400       410       420       430       440       450

              640       650       660       670       680       
pF1KB6 GSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
              460       470       480       490       500       

>>CCDS56369.1 PDE4D gene_id:5144|Hs108|chr5               (518 aa)
 initn: 3304 init1: 3304 opt: 3304  Z-score: 3093.6  bits: 582.4 E(32554): 5.4e-166
Smith-Waterman score: 3304; 100.0% identity (100.0% similar) in 503 aa overlap (185-687:16-518)

          160       170       180       190       200       210    
pF1KB6 ASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNT
                                     ::::::::::::::::::::::::::::::
CCDS56                MPEANYLLSVSWGYIKFKRMLNRELTHLSEMSRSGNQVSEFISNT
                              10        20        30        40     

          220       230       240       250       260       270    
pF1KB6 FLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 FLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAK
          50        60        70        80        90       100     

          280       290       300       310       320       330    
pF1KB6 ELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
         110       120       130       140       150       160     

          340       350       360       370       380       390    
pF1KB6 ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
         170       180       190       200       210       220     

          400       410       420       430       440       450    
pF1KB6 TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMS
         230       240       250       260       270       280     

          460       470       480       490       500       510    
pF1KB6 KHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTD
         290       300       310       320       330       340     

          520       530       540       550       560       570    
pF1KB6 RIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD
         350       360       370       380       390       400     

          580       590       600       610       620       630    
pF1KB6 ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQV
         410       420       430       440       450       460     

          640       650       660       670       680       
pF1KB6 EEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
         470       480       490       500       510        

>>CCDS30742.1 PDE4B gene_id:5142|Hs108|chr1               (721 aa)
 initn: 2834 init1: 2204 opt: 3239  Z-score: 3030.8  bits: 571.3 E(32554): 1.7e-162
Smith-Waterman score: 3239; 77.8% identity (90.8% similar) in 640 aa overlap (20-655:68-702)

                          10        20        30         40        
pF1KB6            MAFVWDPLGATVPGPSTRAKSRLRFSKSYS-FDVDNGTSAGRSPLDPMT
                                     ..: ::. ... :::.:: : :::::::..
CCDS30 NRPTSPKISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQA
        40        50        60        70        80        90       

       50        60         70        80        90       100       
pF1KB6 SPGSGLILQANFV-HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQV
       : ..::.:.:.:  :::::::::::::::::::::.::::::. :. :::::::::::::
CCDS30 SSSAGLVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQV
       100       110       120       130       140       150       

       110       120       130       140       150       160       
pF1KB6 LASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLD
       :::::.:::::. ::::.  . .::::  .:: .....  ::.::::: :::::::::::
CCDS30 LASLRSVRNNFTILTNLHGTS-NKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLD
       160       170        180       190       200       210      

       170       180       190       200       210       220       
pF1KB6 QLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSP
       ::::.:: .:::::::::::::::::::::::::::::::::.:::::::::..::::::
CCDS30 QLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSP
        220       230       240       250       260       270      

       230         240       250       260       270       280     
pF1KB6 TQKEKEKKKRP--MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLH
       :::..::::.   :.::::::::::::::.:.:: ::::.::.:: :::::::.:::::.
CCDS30 TQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLN
        280       290       300       310       320       330      

         290       300       310       320       330       340     
pF1KB6 VFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHA
       .: .:  : ::::: ::..:::::::::::.:  ::.:::.::::::::.::::::..::
CCDS30 IFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHA
        340       350       360       370       380       390      

         350       360       370       380       390       400     
pF1KB6 ADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYND
       :::.::::::::::::.::::::::::::::.::::::::::::::::::::::::::::
CCDS30 ADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYND
        400       410       420       430       440       450      

         410       420       430       440       450       460     
pF1KB6 SSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKT
        ::::::::::::::::::.::::.::::::::.:::::::.::::::::::.:::::::
CCDS30 ESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKT
        460       470       480       490       500       510      

         470       480       490       500       510       520     
pF1KB6 MVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGD
       ::::::::::::::::::.::::::.::::::::::::: :.::::::::::::::.:::
CCDS30 MVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGD
        520       530       540       550       560       570      

         530       540       550       560       570       580     
pF1KB6 RERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREW
       .:::::::::::::::.::::::::::::::::::::::::::.::::::::::::::.:
CCDS30 KERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNW
        580       590       600       610       620       630      

         590       600       610       620       630       640     
pF1KB6 YQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
       ::: :::::::  :. ..  ::  :::::::::.:.     ::..    :  .  :..::
CCDS30 YQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEG----EGHSYFSSTKT
        640       650       660       670       680           690  

         650       660       670       680       
pF1KB6 LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT
       ::. : :. .                                
CCDS30 LCVIDPENRDSLGETDIDIATEDKSPVDT             
            700       710       720              

>>CCDS632.1 PDE4B gene_id:5142|Hs108|chr1                 (736 aa)
 initn: 2834 init1: 2204 opt: 3225  Z-score: 3017.6  bits: 568.9 E(32554): 9.2e-162
Smith-Waterman score: 3225; 78.8% identity (91.1% similar) in 628 aa overlap (31-655:95-717)

               10        20        30        40        50        60
pF1KB6 MAFVWDPLGATVPGPSTRAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
                                     :::.:: : :::::::..: ..::.:.:.:
CCDS63 TPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVLHATF
           70        80        90       100       110       120    

                70        80        90       100       110         
pF1KB6 V-HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
         :::::::::::::::::::::.::::::. :. ::::::::::::::::::.:::::.
CCDS63 PGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVRNNFT
          130       140       150       160       170       180    

     120       130       140       150       160       170         
pF1KB6 ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
        ::::.  . .::::  .:: .....  ::.::::: :::::::::::::::.:: .:::
CCDS63 ILTNLHGTS-NKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYRSVS
          190        200       210       220       230       240   

     180       190       200       210       220       230         
pF1KB6 EMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRP-
       ::::::::::::::::::::::::::::::.:::::::::..:::::::::..::::.  
CCDS63 EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKKKQQ
           250       260       270       280       290       300   

       240       250       260       270       280       290       
pF1KB6 -MSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRP
        :.::::::::::::::.:.:: ::::.::.:: :::::::.:::::..: .:  : :::
CCDS63 LMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSHNRP
           310       320       330       340       350       360   

       300       310       320       330       340       350       
pF1KB6 LTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLS
       :: ::..:::::::::::.:  ::.:::.::::::::.::::::..:::::.::::::::
CCDS63 LTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLS
           370       380       390       400       410       420   

       360       370       380       390       400       410       
pF1KB6 TPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVG
       ::::.::::::::::::::.:::::::::::::::::::::::::::: :::::::::::
CCDS63 TPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVG
           430       440       450       460       470       480   

       420       430       440       450       460       470       
pF1KB6 FKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGV
       :::::::.::::.::::::::.:::::::.::::::::::.:::::::::::::::::::
CCDS63 FKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGV
           490       500       510       520       530       540   

       480       490       500       510       520       530       
pF1KB6 LLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPM
       ::::::.::::::.::::::::::::: :.::::::::::::::.:::.:::::::::::
CCDS63 LLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPM
           550       560       570       580       590       600   

       540       550       560       570       580       590       
pF1KB6 CDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPA
       ::::.::::::::::::::::::::::::::.::::::::::::::.:::: ::::::: 
CCDS63 CDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSPSPP
           610       620       630       640       650       660   

       600       610       620       630       640       650       
pF1KB6 PDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIP
        :. ..  ::  :::::::::.:.     ::..    :  .  :..::::. : :. .  
CCDS63 LDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEG----EGHSYFSSTKTLCVIDPENRDSL
           670       680       690           700       710         

       660       670       680       
pF1KB6 LDEQVEEEAVGEEEESQPEACVIDDRSPDT
                                     
CCDS63 GETDIDIATEDKSPVDT             
     720       730                   




687 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:42:43 2016 done: Sat Nov  5 18:42:44 2016
 Total Scan time:  3.940 Total Display time:  0.210

Function used was FASTA [36.3.4 Apr, 2011]
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