Result of FASTA (omim) for pF1KE0773
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0773, 344 aa
  1>>>pF1KE0773 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.4614+/-0.000593; mu= -4.7659+/- 0.035
 mean_var=522.6926+/-121.801, 0's: 0 Z-trim(115.9): 1959  B-trim: 644 in 1/53
 Lambda= 0.056098
 statistics sampled from 24015 (26646) to 24015 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.312), width:  16
 Scan time:  7.220

The best scores are:                                      opt bits E(85289)
NP_001300879 (OMIM: 604970) aurora kinase B isofor ( 344) 2311 202.3 1.3e-51
NP_004208 (OMIM: 604970) aurora kinase B isoform 1 ( 344) 2311 202.3 1.3e-51
NP_001271455 (OMIM: 604970) aurora kinase B isofor ( 345) 2299 201.3 2.5e-51
NP_001243763 (OMIM: 604970) aurora kinase B isofor ( 303) 2034 179.8 6.6e-45
XP_016880796 (OMIM: 604970) PREDICTED: aurora kina ( 303) 2034 179.8 6.6e-45
NP_001300880 (OMIM: 604970) aurora kinase B isofor ( 303) 2034 179.8 6.6e-45
XP_011522374 (OMIM: 604970) PREDICTED: aurora kina ( 303) 2034 179.8 6.6e-45
NP_001300881 (OMIM: 604970) aurora kinase B isofor ( 304) 2022 178.8 1.3e-44
NP_001015878 (OMIM: 243060,603495) aurora kinase C ( 309) 1590 143.9 4.4e-34
NP_001015879 (OMIM: 243060,603495) aurora kinase C ( 290) 1578 142.9 8.3e-34
NP_003151 (OMIM: 243060,603495) aurora kinase C is ( 275) 1576 142.7 9.1e-34
XP_016880797 (OMIM: 604970) PREDICTED: aurora kina ( 271) 1433 131.1 2.7e-30
XP_011522372 (OMIM: 604970) PREDICTED: aurora kina ( 312) 1433 131.2   3e-30
NP_001300882 (OMIM: 604970) aurora kinase B isofor ( 312) 1433 131.2   3e-30
NP_001310233 (OMIM: 603072) aurora kinase A [Homo  ( 403) 1349 124.6 3.8e-28
NP_940839 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
NP_001310234 (OMIM: 603072) aurora kinase A [Homo  ( 403) 1349 124.6 3.8e-28
NP_940836 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
NP_940835 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
NP_001310232 (OMIM: 603072) aurora kinase A [Homo  ( 403) 1349 124.6 3.8e-28
NP_940838 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
XP_016883524 (OMIM: 603072) PREDICTED: aurora kina ( 403) 1349 124.6 3.8e-28
NP_003591 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
NP_940837 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 1349 124.6 3.8e-28
XP_016883523 (OMIM: 603072) PREDICTED: aurora kina ( 437) 1349 124.6 3.9e-28
XP_016880798 (OMIM: 604970) PREDICTED: aurora kina ( 192) 1132 106.5 4.9e-23
XP_016880799 (OMIM: 604970) PREDICTED: aurora kina ( 192) 1132 106.5 4.9e-23
NP_001300883 (OMIM: 604970) aurora kinase B isofor ( 192) 1132 106.5 4.9e-23
XP_016880800 (OMIM: 604970) PREDICTED: aurora kina ( 192) 1132 106.5 4.9e-23
NP_001300884 (OMIM: 604970) aurora kinase B isofor ( 176) 1125 105.9   7e-23
XP_005262758 (OMIM: 605031,616171) PREDICTED: seri ( 936)  633 67.2 1.6e-10
XP_016863152 (OMIM: 605031,616171) PREDICTED: seri ( 937)  633 67.2 1.6e-10
NP_055079 (OMIM: 605031,616171) serine/threonine-p ( 970)  633 67.2 1.7e-10
XP_016863151 (OMIM: 605031,616171) PREDICTED: seri ( 971)  633 67.2 1.7e-10
NP_001248745 (OMIM: 605213) 3-phosphoinositide-dep ( 454)  575 62.0 2.9e-09
XP_016878763 (OMIM: 605213) PREDICTED: 3-phosphoin ( 539)  575 62.1 3.2e-09
NP_002604 (OMIM: 605213) 3-phosphoinositide-depend ( 556)  575 62.1 3.2e-09
XP_016878762 (OMIM: 605213) PREDICTED: 3-phosphoin ( 566)  575 62.2 3.2e-09
XP_016878761 (OMIM: 605213) PREDICTED: 3-phosphoin ( 568)  575 62.2 3.3e-09
XP_011520823 (OMIM: 605213) PREDICTED: 3-phosphoin ( 590)  575 62.2 3.3e-09
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661)  576 62.3 3.3e-09
XP_016878760 (OMIM: 605213) PREDICTED: 3-phosphoin ( 600)  575 62.2 3.3e-09
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660)  568 61.7 5.2e-09
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213)  568 62.1 7.2e-09
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261)  568 62.1 7.3e-09
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261)  568 62.1 7.3e-09
NP_005035 (OMIM: 300083) cAMP-dependent protein ki ( 358)  556 60.3 7.4e-09
NP_006613 (OMIM: 607023) serine/threonine-protein  ( 685)  562 61.2 7.4e-09
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309)  568 62.2 7.5e-09
NP_079440 (OMIM: 614776) serine/threonine-protein  (1321)  568 62.2 7.5e-09


>>NP_001300879 (OMIM: 604970) aurora kinase B isoform 1   (344 aa)
 initn: 2311 init1: 2311 opt: 2311  Z-score: 1047.8  bits: 202.3 E(85289): 1.3e-51
Smith-Waterman score: 2311; 99.7% identity (99.7% similar) in 344 aa overlap (1-344:1-344)

               10        20        30        40        50        60
pF1KE0 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
              250       260       270       280       290       300

              310       320       330       340    
pF1KE0 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              310       320       330       340    

>>NP_004208 (OMIM: 604970) aurora kinase B isoform 1 [Ho  (344 aa)
 initn: 2311 init1: 2311 opt: 2311  Z-score: 1047.8  bits: 202.3 E(85289): 1.3e-51
Smith-Waterman score: 2311; 99.7% identity (99.7% similar) in 344 aa overlap (1-344:1-344)

               10        20        30        40        50        60
pF1KE0 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_004 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
              250       260       270       280       290       300

              310       320       330       340    
pF1KE0 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       ::::::::::::::::::::::::::::::::::::::::::::
NP_004 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              310       320       330       340    

>>NP_001271455 (OMIM: 604970) aurora kinase B isoform 3   (345 aa)
 initn: 1854 init1: 1854 opt: 2299  Z-score: 1042.6  bits: 201.3 E(85289): 2.5e-51
Smith-Waterman score: 2299; 99.4% identity (99.4% similar) in 345 aa overlap (1-344:1-345)

               10        20        30        40        50        60
pF1KE0 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
               10        20        30        40        50        60

               70         80        90       100       110         
pF1KE0 SSGTPDILTR-HFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVE
       :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGTPDILTRRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVE
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE0 HQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTAT
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KE0 IMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDY
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE0 LPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 LPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMG
              250       260       270       280       290       300

     300       310       320       330       340    
pF1KE0 AQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       :::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              310       320       330       340     

>>NP_001243763 (OMIM: 604970) aurora kinase B isoform 2   (303 aa)
 initn: 2034 init1: 2034 opt: 2034  Z-score: 927.2  bits: 179.8 E(85289): 6.6e-45
Smith-Waterman score: 2034; 99.7% identity (99.7% similar) in 303 aa overlap (42-344:1-303)

              20        30        40        50        60        70 
pF1KE0 YGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                     ::::::::::::::::::::::::::::::
NP_001                               MSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                             10        20        30

              80        90       100       110       120       130 
pF1KE0 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KE0 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KE0 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KE0 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN
              220       230       240       250       260       270

             320       330       340    
pF1KE0 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       :::::::::::::::::::::::::::::::::
NP_001 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              280       290       300   

>>XP_016880796 (OMIM: 604970) PREDICTED: aurora kinase B  (303 aa)
 initn: 2034 init1: 2034 opt: 2034  Z-score: 927.2  bits: 179.8 E(85289): 6.6e-45
Smith-Waterman score: 2034; 99.7% identity (99.7% similar) in 303 aa overlap (42-344:1-303)

              20        30        40        50        60        70 
pF1KE0 YGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                     ::::::::::::::::::::::::::::::
XP_016                               MSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                             10        20        30

              80        90       100       110       120       130 
pF1KE0 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KE0 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KE0 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KE0 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN
              220       230       240       250       260       270

             320       330       340    
pF1KE0 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       :::::::::::::::::::::::::::::::::
XP_016 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              280       290       300   

>>NP_001300880 (OMIM: 604970) aurora kinase B isoform 2   (303 aa)
 initn: 2034 init1: 2034 opt: 2034  Z-score: 927.2  bits: 179.8 E(85289): 6.6e-45
Smith-Waterman score: 2034; 99.7% identity (99.7% similar) in 303 aa overlap (42-344:1-303)

              20        30        40        50        60        70 
pF1KE0 YGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                     ::::::::::::::::::::::::::::::
NP_001                               MSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                             10        20        30

              80        90       100       110       120       130 
pF1KE0 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KE0 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KE0 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KE0 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_001 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN
              220       230       240       250       260       270

             320       330       340    
pF1KE0 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       :::::::::::::::::::::::::::::::::
NP_001 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              280       290       300   

>>XP_011522374 (OMIM: 604970) PREDICTED: aurora kinase B  (303 aa)
 initn: 2034 init1: 2034 opt: 2034  Z-score: 927.2  bits: 179.8 E(85289): 6.6e-45
Smith-Waterman score: 2034; 99.7% identity (99.7% similar) in 303 aa overlap (42-344:1-303)

              20        30        40        50        60        70 
pF1KE0 YGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                     ::::::::::::::::::::::::::::::
XP_011                               MSRSNVQPTAAPGQKVMENSSGTPDILTRH
                                             10        20        30

              80        90       100       110       120       130 
pF1KE0 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAH
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KE0 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYC
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KE0 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHN
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KE0 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHN
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHN
              220       230       240       250       260       270

             320       330       340    
pF1KE0 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       :::::::::::::::::::::::::::::::::
XP_011 PSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              280       290       300   

>>NP_001300881 (OMIM: 604970) aurora kinase B isoform 4   (304 aa)
 initn: 1854 init1: 1854 opt: 2022  Z-score: 921.9  bits: 178.8 E(85289): 1.3e-44
Smith-Waterman score: 2022; 99.3% identity (99.3% similar) in 304 aa overlap (42-344:1-304)

              20        30        40        50        60        70 
pF1KE0 YGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTR-
                                     ::::::::::::::::::::::::::::: 
NP_001                               MSRSNVQPTAAPGQKVMENSSGTPDILTRR
                                             10        20        30

               80        90       100       110       120       130
pF1KE0 HFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQA
               40        50        60        70        80        90

              140       150       160       170       180       190
pF1KE0 HLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMY
              100       110       120       130       140       150

              200       210       220       230       240       250
pF1KE0 CHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMH
              160       170       180       190       200       210

              260       270       280       290       300       310
pF1KE0 NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRH
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRH
              220       230       240       250       260       270

              320       330       340    
pF1KE0 NPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       ::::::::::::::::::::::::::::::::::
NP_001 NPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
              280       290       300    

>>NP_001015878 (OMIM: 243060,603495) aurora kinase C iso  (309 aa)
 initn: 1576 init1: 1576 opt: 1590  Z-score: 732.9  bits: 143.9 E(85289): 4.4e-34
Smith-Waterman score: 1590; 77.0% identity (90.3% similar) in 309 aa overlap (35-339:3-305)

           10        20        30        40        50            60
pF1KE0 ENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPT----AAPGQKVMEN
                                     .: :.: ....  ::.    :. .: ... 
NP_001                             MSSPRAVVQLGKA--QPAGEELATANQTAQQP
                                           10          20        30

               70        80        90       100       110       120
pF1KE0 SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
       ::  : .  :..:.::::::::::::::::::::: :.:::::::::::::::::::.::
NP_001 SS--PAM--RRLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEH
                   40        50        60        70        80      

              130       140       150       160       170       180
pF1KE0 QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
       ::::::::::::.:::::::::::.: ::.:::::::::::::::::::  .::::::::
NP_001 QLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATI
         90       100       110       120       130       140      

              190       200       210       220       230       240
pF1KE0 MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
       .::::::: ::: ::::::::::::::::..::.::::::::::.:::::::::::::::
NP_001 IEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYL
        150       160       170       180       190       200      

              250       260       270       280       290       300
pF1KE0 PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGA
       :::::::: ..:::::::::::::::::: ::::::::.::::::.:::..:: :.: ::
NP_001 PPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA
        210       220       230       240       250       260      

              310       320       330       340    
pF1KE0 QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
       .::::.:::..: :::::::.  ::::.:.::::::: :     
NP_001 RDLISRLLRYQPLERLPLAQILKHPWVQAHSRRVLPPCAQMAS 
        270       280       290       300          

>>NP_001015879 (OMIM: 243060,603495) aurora kinase C iso  (290 aa)
 initn: 1559 init1: 1559 opt: 1578  Z-score: 727.9  bits: 142.9 E(85289): 8.3e-34
Smith-Waterman score: 1578; 80.6% identity (92.4% similar) in 289 aa overlap (51-339:2-286)

               30        40        50        60        70        80
pF1KE0 LSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIG
                                     :. .: ... ::  : .  :..:.::::::
NP_001                              MATANQTAQQPSS--PAM--RRLTVDDFEIG
                                            10            20       

               90       100       110       120       130       140
pF1KE0 RPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRL
       ::::::::::::::: :.:::::::::::::::::::.::::::::::::::.:::::::
NP_001 RPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRL
        30        40        50        60        70        80       

              150       160       170       180       190       200
pF1KE0 YNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRD
       ::::.: ::.:::::::::::::::::::  .::::::::.::::::: ::: :::::::
NP_001 YNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRD
        90       100       110       120       130       140       

              210       220       230       240       250       260
pF1KE0 IKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIG
       :::::::::..::.::::::::::.::::::::::::::::::::::: ..:::::::::
NP_001 IKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIG
       150       160       170       180       190       200       

              270       280       290       300       310       320
pF1KE0 VLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQ
       ::::::::: ::::::::.::::::.:::..:: :.: ::.::::.:::..: :::::::
NP_001 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQ
       210       220       230       240       250       260       

              330       340    
pF1KE0 VSAHPWVRANSRRVLPPSALQSVA
       .  ::::.:.::::::: :     
NP_001 ILKHPWVQAHSRRVLPPCAQMAS 
       270       280       290 




344 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:38:53 2016 done: Sat Nov  5 18:38:55 2016
 Total Scan time:  7.220 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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