Result of FASTA (omim) for pF1KB6572
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6572, 400 aa
  1>>>pF1KB6572 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1181+/-0.000394; mu= 19.0651+/- 0.025
 mean_var=109.6049+/-28.386, 0's: 0 Z-trim(113.1): 479  B-trim: 2345 in 2/51
 Lambda= 0.122507
 statistics sampled from 21528 (22226) to 21528 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.261), width:  16
 Scan time:  8.740

The best scores are:                                      opt bits E(85289)
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 2660 481.4 1.7e-135
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 2660 481.4 1.7e-135
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 2660 481.4 1.7e-135
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 2660 481.4 1.7e-135
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 1910 348.8 1.3e-95
XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) ( 443)  898 170.0 9.8e-42
NP_000786 (OMIM: 126450,159900) D(2) dopamine rece ( 443)  898 170.0 9.8e-42
NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414)  896 169.6 1.2e-41
NP_000788 (OMIM: 126452,143465,601696) D(4) dopami ( 419)  596 116.6 1.1e-25
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422)  487 97.4   7e-20
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308)  478 95.6 1.7e-19
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317)  478 95.6 1.8e-19
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324)  478 95.6 1.8e-19
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342)  478 95.7 1.9e-19
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370)  478 95.7 1.9e-19
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372)  478 95.7   2e-19
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465)  468 94.1 7.6e-19
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432)  467 93.9 8.3e-19
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445)  467 93.9 8.4e-19
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479)  467 93.9 8.8e-19
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462)  455 91.8 3.7e-18
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328)  452 91.1 4.4e-18
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331)  452 91.1 4.4e-18
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366)  452 91.1 4.7e-18
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450)  453 91.4 4.7e-18
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389)  452 91.1 4.9e-18
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402)  452 91.2   5e-18
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556)  452 91.3 6.1e-18
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390)  431 87.4 6.4e-17
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458)  431 87.5   7e-17
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458)  431 87.5   7e-17
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471)  410 83.8 9.4e-16
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic  ( 477)  385 79.4   2e-14
NP_076917 (OMIM: 601305) 5-hydroxytryptamine recep ( 357)  382 78.7 2.4e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413)  380 78.4 3.4e-14
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439)  373 77.2 8.4e-14
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456)  373 77.3 8.6e-14
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481)  373 77.3 8.9e-14
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446)  372 77.1 9.5e-14
NP_000789 (OMIM: 126453,143465,606798) D(1B) dopam ( 477)  361 75.2 3.8e-13
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440)  357 74.4 5.9e-13
NP_000729 (OMIM: 118510) muscarinic acetylcholine  ( 460)  344 72.1   3e-12
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic  ( 460)  344 72.1   3e-12
XP_011536797 (OMIM: 606383) PREDICTED: G-protein c ( 396)  334 70.3 9.3e-12
NP_065103 (OMIM: 606383) G-protein coupled recepto ( 396)  334 70.3 9.3e-12
NP_778237 (OMIM: 608923) trace amine-associated re ( 345)  326 68.8 2.3e-11
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360)  325 68.7 2.6e-11
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378)  325 68.7 2.7e-11
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387)  325 68.7 2.8e-11
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388)  325 68.7 2.8e-11


>>XP_016861318 (OMIM: 126451,181500,190300) PREDICTED: D  (400 aa)
 initn: 2660 init1: 2660 opt: 2660  Z-score: 2553.8  bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       ::::::::::::::::::::::::::::::::::::::::
XP_016 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
              370       380       390       400

>>NP_001277738 (OMIM: 126451,181500,190300) D(3) dopamin  (400 aa)
 initn: 2660 init1: 2660 opt: 2660  Z-score: 2553.8  bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       ::::::::::::::::::::::::::::::::::::::::
NP_001 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
              370       380       390       400

>>NP_000787 (OMIM: 126451,181500,190300) D(3) dopamine r  (400 aa)
 initn: 2660 init1: 2660 opt: 2660  Z-score: 2553.8  bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       ::::::::::::::::::::::::::::::::::::::::
NP_000 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
              370       380       390       400

>>NP_001269492 (OMIM: 126451,181500,190300) D(3) dopamin  (400 aa)
 initn: 2660 init1: 2660 opt: 2660  Z-score: 2553.8  bits: 481.4 E(85289): 1.7e-135
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)

               10        20        30        40        50        60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
              310       320       330       340       350       360

              370       380       390       400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       ::::::::::::::::::::::::::::::::::::::::
NP_001 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
              370       380       390       400

>>NP_387512 (OMIM: 126451,181500,190300) D(3) dopamine r  (367 aa)
 initn: 1910 init1: 1910 opt: 1910  Z-score: 1837.8  bits: 348.8 E(85289): 1.3e-95
Smith-Waterman score: 2372; 91.5% identity (91.8% similar) in 400 aa overlap (1-400:1-367)

               10        20        30        40        50        60
pF1KB6 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::              
NP_387 QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSL--------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB6 LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
                          .::::::::::::::::::::::::::::::::::::::::
NP_387 -------------------MPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
                           290       300       310       320       

              370       380       390       400
pF1KB6 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       ::::::::::::::::::::::::::::::::::::::::
NP_387 SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
       330       340       350       360       

>>XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) dop  (443 aa)
 initn: 1091 init1: 303 opt: 898  Z-score: 870.2  bits: 170.0 E(85289): 9.8e-42
Smith-Waterman score: 1245; 53.4% identity (71.1% similar) in 425 aa overlap (19-394:23-437)

                   10        20         30        40        50     
pF1KB6     MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
                             :.. ..  :::  :::     :: .::::: :::::: 
XP_016 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
       .:.:::::::::.:::::::::::::::::::::::.:  :.:::: ::.::::::::::
XP_016 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
               70        80        90        100       110         

         120       130       140       150       160       170     
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
       :::::::::::::::::.::. :.  :  :: :::..::. ::::.:..:::::::.:..
XP_016 ASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
     120       130       140         150       160       170       

         180       190       200       210       220       230     
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQC----
        : . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:.     
XP_016 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
        180       190       200       210        220       230     

                                  240           250                
pF1KB6 -------NSVRP--------------GFPQQTLSPDPAH----LELK-----------RY
              : ..:              .:: .    . :.    ::..           ::
XP_016 LRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRY
         240       250       260       270       280       290     

            260          270       280        290       300        
pF1KB6 YSI---CQDTALGGP---GFQERGGELKREEKTRNSLS-PTIAPKLSLEVRKLSNGRLST
         :    .. .:  :   :..       . ::. .. . : :: :. .:.. . ::.  :
XP_016 SPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIA-KI-FEIQTMPNGKTRT
         300       310       320       330        340        350   

      310       320        330       340       350       360       
pF1KB6 SLKLGPLQPRGVPL-REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSA
       :::   .. : .   .:::::::.:::::.::.::::::.::.:: ::. :.. : ::::
XP_016 SLKT--MSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSA
             360       370       380       390       400        410

       370       380       390       400
pF1KB6 TTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
        :::::::::.::.:::::::::::::      
XP_016 FTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
              420       430       440   

>>NP_000786 (OMIM: 126450,159900) D(2) dopamine receptor  (443 aa)
 initn: 1091 init1: 303 opt: 898  Z-score: 870.2  bits: 170.0 E(85289): 9.8e-42
Smith-Waterman score: 1245; 53.4% identity (71.1% similar) in 425 aa overlap (19-394:23-437)

                   10        20         30        40        50     
pF1KB6     MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
                             :.. ..  :::  :::     :: .::::: :::::: 
NP_000 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
       .:.:::::::::.:::::::::::::::::::::::.:  :.:::: ::.::::::::::
NP_000 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
               70        80        90        100       110         

         120       130       140       150       160       170     
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
       :::::::::::::::::.::. :.  :  :: :::..::. ::::.:..:::::::.:..
NP_000 ASILNLCAISIDRYTAVAMPMLYN--TRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
     120       130       140         150       160       170       

         180       190       200       210       220       230     
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQC----
        : . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:.     
NP_000 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
        180       190       200       210        220       230     

                                  240           250                
pF1KB6 -------NSVRP--------------GFPQQTLSPDPAH----LELK-----------RY
              : ..:              .:: .    . :.    ::..           ::
NP_000 LRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRY
         240       250       260       270       280       290     

            260          270       280        290       300        
pF1KB6 YSI---CQDTALGGP---GFQERGGELKREEKTRNSLS-PTIAPKLSLEVRKLSNGRLST
         :    .. .:  :   :..       . ::. .. . : :: :. .:.. . ::.  :
NP_000 SPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIA-KI-FEIQTMPNGKTRT
         300       310       320       330        340        350   

      310       320        330       340       350       360       
pF1KB6 SLKLGPLQPRGVPL-REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSA
       :::   .. : .   .:::::::.:::::.::.::::::.::.:: ::. :.. : ::::
NP_000 SLKT--MSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCD-CNIPPVLYSA
             360       370       380       390       400        410

       370       380       390       400
pF1KB6 TTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
        :::::::::.::.:::::::::::::      
NP_000 FTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
              420       430       440   

>>NP_057658 (OMIM: 126450,159900) D(2) dopamine receptor  (414 aa)
 initn: 1057 init1: 303 opt: 896  Z-score: 868.7  bits: 169.6 E(85289): 1.2e-41
Smith-Waterman score: 1323; 56.7% identity (75.1% similar) in 402 aa overlap (19-400:23-414)

                   10        20         30        40        50     
pF1KB6     MASLSQLSGHLNYTCGAENSTGASQARPH-AYYALSYCALILAIVFGNGLVCMAVL
                             :.. ..  :::  :::     :: .::::: :::::: 
NP_057 MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
       .:.:::::::::.:::::::::::::::::::::::.:  :.:::: ::.::::::::::
NP_057 REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGE-WKFSRIHCDIFVTLDVMMCT
               70        80        90        100       110         

         120       130       140       150       160       170     
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
       :::::::::::::::::.::. :  .:  :: :::..::. ::::.:..:::::::.:..
NP_057 ASILNLCAISIDRYTAVAMPMLY--NTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA
     120       130       140         150       160       170       

         180       190       200       210       220       230     
pF1KB6 GDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVR
        : . : :.:: ::.:::.::::.:: ::.::: .::.::. :::::. :...:.   ..
NP_057 -DQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLR-RRRKRVNTKRSSRAFRAH
        180       190       200       210        220       230     

         240       250                     260          270        
pF1KB6 PGFPQQTLSPDPAHLELK-----------RYYSI---CQDTALGGP---GFQERGGELKR
          : .  .    .::..           ::  :    .. .:  :   :..       .
NP_057 LRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAK
         240       250       260       270       280       290     

      280        290       300       310       320        330      
pF1KB6 EEKTRNSLS-PTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPL-REKKATQMVAIVLG
        ::. .. . : :: :. .:.. . ::.  ::::   .. : .   .:::::::.:::::
NP_057 PEKNGHAKDHPKIA-KI-FEIQTMPNGKTRTSLK--TMSRRKLSQQKEKKATQMLAIVLG
         300        310        320         330       340       350 

        340       350       360       370       380       390      
pF1KB6 AFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLK
       .::.::::::.::.:: ::. :.. : :::: :::::::::.::.:::::::::::::::
NP_057 VFIICWLPFFITHILNIHCD-CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLK
             360       370        380       390       400       410

        400
pF1KB6 ILSC
       :: :
NP_057 ILHC
           

>>NP_000788 (OMIM: 126452,143465,601696) D(4) dopamine r  (419 aa)
 initn: 871 init1: 403 opt: 596  Z-score: 582.0  bits: 116.6 E(85289): 1.1e-25
Smith-Waterman score: 884; 40.9% identity (63.7% similar) in 408 aa overlap (16-400:21-418)

                    10        20        30        40        50     
pF1KB6      MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVL
                           ::  ...:. :   :   ..   :: :.. ::.:::..: 
NP_000 MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB6 KERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCT
        :::::: :: ..::::.::::.: ::.:  :: :: ::.: .:   ::.....:::.::
NP_000 TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB6 ASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTT
       :::.::::::.::..::..:..:..   :.. ::  :.: :.:.:. ::. :.: :.: .
NP_000 ASIFNLCAISVDRFVAVAVPLRYNR---QGGSRRQLLLIGATWLLSAAVAAPVLCGLNDV
              130       140          150       160       170       

           180       190       200       210          220       230
pF1KB6 -G-DPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQ---RRRKRILTRQNSQ
        : ::.:: . . :.:.:::: ::.::  . .:.:   .  :..    :: ..  :   .
NP_000 RGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRR
       180       190       200       210       220       230       

              240       250       260             270       280    
pF1KB6 CNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALG------GPGFQERGGELKREEKTRN
        ..  :: :. :  : : .:        :   : :      ::     .  : ..    .
NP_000 PSG--PGPPSPT-PPAP-RLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPD
       240          250        260       270       280       290   

          290       300       310       320                  330   
pF1KB6 SLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPL-----------REKKATQMVAI
          :  :: :  .    ::     ... . : :.  :            ::.:: ... .
NP_000 CAPP--APGLPPDPCG-SNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPV
             300        310       320       330       340       350

           340       350       360       370       380       390   
pF1KB6 VLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKA
       :.:::..:: :::..:. .. : .: : :.: ::.::::::::::::::::.:: :::..
NP_000 VVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNV
              360       370       380       390       400       410

            400 
pF1KB6 FLKIL-SC 
       : : : .: 
NP_000 FRKALRACC
                

>>NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamine re  (422 aa)
 initn: 602 init1: 185 opt: 487  Z-score: 477.9  bits: 97.4 E(85289): 7e-20
Smith-Waterman score: 734; 32.8% identity (65.7% similar) in 408 aa overlap (19-400:24-417)

                    10        20          30        40        50   
pF1KB6      MASLSQLSGHLNYTCGAENSTGASQARP--HAYYALSYCALILAIVFGNGLVCMA
                              :.:: :..    ..  .:   .::.  :.::. :  :
NP_000 MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB6 VLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMM
       .  ::.::...:::. ::::.::.:..::.: ..  .: .  :..... ::.:..:::. 
NP_000 IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNK-WTLGQVTCDLFIALDVLC
               70        80        90       100        110         

           120       130       140       150       160       170   
pF1KB6 CTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFN
       ::.:::.::::..::: :.. :. :   ... . ::.: .:. .:...: .: : ..:. 
NP_000 CTSSILHLCAIALDRYWAITDPIDY---VNKRTPRRAAALISLTWLIGFLISIPPMLGWR
     120       130       140          150       160       170      

              180        190       200       210       220         
pF1KB6 TT---GDPTVCSIS-NPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNS
       :    .:: .:.:: .  ..:::.  .::.:. . ...:.::. . . : :: .   ...
NP_000 TPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKT
        180       190       200       210       220       230      

     230            240             250       260         270      
pF1KB6 QCNSVRPGF-----PQQTLSPDPAH------LELKRYYSICQDTAL--GGPGFQERGGEL
         .. : :      :..... . .       .: :   ..: . :.  :  :   .  :.
NP_000 GADT-RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEV
        240        250       260       270       280       290     

        280             290       300       310       320       330
pF1KB6 KREEKTRNSL------SPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQM
       .:  .... :      .::     :.: ..  :.. . .. :.         ::.:... 
NP_000 HRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALA---------RERKTVKT
         300       310       320       330                340      

              340       350        360       370       380         
pF1KB6 VAIVLGAFIVCWLPFFLTHVLNTHCQT-CHVSPELYSATTWLGYVNSALNPVIYTTFNIE
       ..:..:.::.::::::.. ..   :.. ::.   : .  .:::: :: ::::::. :: .
NP_000 LGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKD
        350       360       370       380       390       400      

     390       400     
pF1KB6 FRKAFLKILSC     
       :..:: ::..:     
NP_000 FQNAFKKIIKCKFCRQ
        410       420  




400 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 18:12:31 2016 done: Sat Nov  5 18:12:33 2016
 Total Scan time:  8.740 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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