Result of FASTA (omim) for pF1KB0945
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0945, 170 aa
  1>>>pF1KB0945 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6923+/-0.000447; mu= 11.2195+/- 0.028
 mean_var=116.7858+/-22.535, 0's: 0 Z-trim(112.8): 240  B-trim: 52 in 2/52
 Lambda= 0.118680
 statistics sampled from 21499 (21886) to 21499 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.257), width:  16
 Scan time:  5.260

The best scores are:                                      opt bits E(85289)
NP_000936 (OMIM: 601302) calcineurin subunit B typ ( 170) 1123 203.0   2e-52
NP_671709 (OMIM: 613821) calcineurin subunit B typ ( 173)  950 173.4 1.6e-43
NP_008819 (OMIM: 114180,614916,616247) calmodulin  ( 149)  302 62.3 3.7e-10
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149)  302 62.3 3.7e-10
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149)  302 62.3 3.7e-10
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149)  302 62.3 3.7e-10
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150)  296 61.3 7.6e-10
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197)  296 61.4 9.1e-10
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149)  289 60.1 1.7e-09
NP_009167 (OMIM: 606988) calcineurin B homologous  ( 195)  289 60.2 2.1e-09
NP_001245288 (OMIM: 600207) hippocalcin-like prote ( 193)  272 57.3 1.6e-08
XP_016859441 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
NP_002140 (OMIM: 600207) hippocalcin-like protein  ( 193)  272 57.3 1.6e-08
XP_016859440 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_011508650 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_011508648 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_005246219 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_005246218 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_005246220 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
NP_001245286 (OMIM: 600207) hippocalcin-like prote ( 193)  272 57.3 1.6e-08
XP_016859442 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
XP_016859439 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
NP_001245287 (OMIM: 600207) hippocalcin-like prote ( 193)  272 57.3 1.6e-08
XP_005246217 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
NP_602293 (OMIM: 600207) hippocalcin-like protein  ( 193)  272 57.3 1.6e-08
XP_011508649 (OMIM: 600207) PREDICTED: hippocalcin ( 193)  272 57.3 1.6e-08
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  263 55.5 3.2e-08
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113)  263 55.5 3.2e-08
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113)  263 55.5 3.2e-08
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  263 55.5 3.2e-08
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  263 55.5 3.2e-08
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  263 55.5 3.2e-08
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113)  263 55.5 3.2e-08
NP_001258817 (OMIM: 605564,609439,614869) calcium  ( 144)  263 55.6 3.7e-08
XP_006720437 (OMIM: 605564,609439,614869) PREDICTE ( 144)  263 55.6 3.7e-08
XP_011515636 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
NP_001035715 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
XP_016869391 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
NP_001035718 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
NP_001035719 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
XP_011515635 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
NP_001035720 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
XP_016869390 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
NP_114430 (OMIM: 606722) neurocalcin-delta [Homo s ( 193)  264 55.9   4e-08
NP_001035714 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
NP_001035717 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
XP_011515634 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
XP_011515637 (OMIM: 606722) PREDICTED: neurocalcin ( 193)  264 55.9   4e-08
NP_001035716 (OMIM: 606722) neurocalcin-delta [Hom ( 193)  264 55.9   4e-08
XP_011519463 (OMIM: 605564,609439,614869) PREDICTE ( 167)  263 55.7 4.1e-08


>>NP_000936 (OMIM: 601302) calcineurin subunit B type 1   (170 aa)
 initn: 1123 init1: 1123 opt: 1123  Z-score: 1062.3  bits: 203.0 E(85289): 2e-52
Smith-Waterman score: 1123; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
               70        80        90       100       110       120

              130       140       150       160       170
pF1KB0 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
              130       140       150       160       170

>>NP_671709 (OMIM: 613821) calcineurin subunit B type 2   (173 aa)
 initn: 1026 init1: 950 opt: 950  Z-score: 902.2  bits: 173.4 E(85289): 1.6e-43
Smith-Waterman score: 950; 84.7% identity (92.9% similar) in 170 aa overlap (1-170:4-173)

                  10        20        30        40        50       
pF1KB0    MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR
          :::::::: ::::::: :::::::.::::::::.:::::::::::::::..::::.:
NP_671 MSTMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRR
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB0 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK
       :::.:::::.::::::::: :.::::::::.:::::::: ::::::::::::::::::::
NP_671 VIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLK
               70        80        90       100       110       120

       120       130       140       150       160       170
pF1KB0 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
       ::::::: : ::::.::::::  ::::::.:::::: :::  :.::::.:. :
NP_671 MMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV
              130       140       150       160       170   

>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom  (149 aa)
 initn: 253 init1: 176 opt: 302  Z-score: 303.3  bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
                 : ...  ..: .. . :. .: :..:.....:. . .  : :::    .:
NP_008           MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
                         10        20        30        40        50

         60        70        80        90       100       110      
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
        .:.  :.:::: .:: ::.  ...     :.:...: :::..: : .:::: .:: .:.
NP_008 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
               60        70        80        90       100       110

        120       130       140       150       160       170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
         . :..: : .    ::. : .:: ::::....:::                 
NP_008 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK          
               120           130       140                   

>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [  (149 aa)
 initn: 253 init1: 176 opt: 302  Z-score: 303.3  bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
                 : ...  ..: .. . :. .: :..:.....:. . .  : :::    .:
NP_001           MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
                         10        20        30        40        50

         60        70        80        90       100       110      
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
        .:.  :.:::: .:: ::.  ...     :.:...: :::..: : .:::: .:: .:.
NP_001 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
               60        70        80        90       100       110

        120       130       140       150       160       170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
         . :..: : .    ::. : .:: ::::....:::                 
NP_001 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK          
               120           130       140                   

>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo  (149 aa)
 initn: 253 init1: 176 opt: 302  Z-score: 303.3  bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
                 : ...  ..: .. . :. .: :..:.....:. . .  : :::    .:
NP_001           MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
                         10        20        30        40        50

         60        70        80        90       100       110      
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
        .:.  :.:::: .:: ::.  ...     :.:...: :::..: : .:::: .:: .:.
NP_001 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
               60        70        80        90       100       110

        120       130       140       150       160       170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
         . :..: : .    ::. : .:: ::::....:::                 
NP_001 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK          
               120           130       140                   

>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa  (149 aa)
 initn: 253 init1: 176 opt: 302  Z-score: 303.3  bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
                 : ...  ..: .. . :. .: :..:.....:. . .  : :::    .:
NP_005           MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
                         10        20        30        40        50

         60        70        80        90       100       110      
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
        .:.  :.:::: .:: ::.  ...     :.:...: :::..: : .:::: .:: .:.
NP_005 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
               60        70        80        90       100       110

        120       130       140       150       160       170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
         . :..: : .    ::. : .:: ::::....:::                 
NP_005 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK          
               120           130       140                   

>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c  (150 aa)
 initn: 253 init1: 176 opt: 296  Z-score: 297.7  bits: 61.3 E(85289): 7.6e-10
Smith-Waterman score: 296; 36.4% identity (69.3% similar) in 140 aa overlap (18-153:9-143)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
                        ..: .. . :. .: :..:.....:. . .  : :::    .:
XP_006          MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
                        10        20        30        40        50 

         60        70        80        90       100       110      
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
        .:.  :.:::: .:: ::.  ...     :.:...: :::..: : .:::: .:: .:.
XP_006 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
              60        70        80        90       100       110 

        120       130       140       150       160       170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
         . :..: : .    ::. : .:: ::::....:::                 
XP_006 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK          
              120           130       140       150          

>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform   (197 aa)
 initn: 253 init1: 176 opt: 296  Z-score: 296.3  bits: 61.4 E(85289): 9.1e-10
Smith-Waterman score: 296; 36.4% identity (69.3% similar) in 140 aa overlap (18-153:56-190)

                            10        20        30        40       
pF1KB0              MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-L
                                     ..: .. . :. .: :..:.....:. . .
NP_001 RKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVM
          30        40        50        60        70        80     

         50           60        70        80        90       100   
pF1KB0 PELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK
         : :::    .: .:.  :.:::: .:: ::.  ...     :.:...: :::..: : 
NP_001 RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDG
          90       100       110       120       130       140     

           110       120       130       140       150       160   
pF1KB0 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH
       .:::: .:: .:.  . :..: : .    ::. : .:: ::::....:::          
NP_001 NGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK   
         150       160            170       180       190          

           170
pF1KB0 KKMVVDV

>>NP_005176 (OMIM: 114184) calmodulin-like protein 3 [Ho  (149 aa)
 initn: 308 init1: 160 opt: 289  Z-score: 291.3  bits: 60.1 E(85289): 1.7e-09
Smith-Waterman score: 289; 34.2% identity (67.8% similar) in 152 aa overlap (11-157:1-146)

               10        20        30        40         50         
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVI
                 : ...  ... .. . :. .: :..: ....:. . .  : :::   .. 
NP_005           MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELR
                         10        20        30        40        50

      60           70        80         90       100       110     
pF1KB0 DIF---DTDGNGEVDFKEFIEGVSQFSVKG-DKEQKLRFAFRIYDMDKDGYISNGELFQV
       :..   : :::: ::: ::. :.   ..:  :.:...: :::..: : .:..: .:: .:
NP_005 DMMSEIDRDGNGTVDFPEFL-GMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHV
               60        70         80        90       100         

         120       130       140       150       160       170
pF1KB0 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
       .  . :..:.: .    ::. :  :: ::::....:::  :.             
NP_005 MTRL-GEKLSDEE----VDEMIRAADTDGDGQVNYEEFVRVLVSK          
     110        120           130       140                   

>>NP_009167 (OMIM: 606988) calcineurin B homologous prot  (195 aa)
 initn: 436 init1: 287 opt: 289  Z-score: 289.9  bits: 60.2 E(85289): 2.1e-09
Smith-Waterman score: 431; 43.2% identity (69.8% similar) in 169 aa overlap (15-168:23-191)

                       10        20        30        40        50  
pF1KB0         MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN
                             :. ..: :: .:: .::  ..:.:: :.:. .:::  :
NP_009 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN
               10        20        30        40        50        60

             60        70        80        90                      
pF1KB0 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ---------------KLRFAFR
       :: .:.:. :  .:. .:.:. :.. ...:    :.:.               ::.::::
NP_009 PLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFR
               70        80        90       100       110       120

       100       110       120       130       140       150       
pF1KB0 IYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV
       .::.:::  ::  ::.:::.:::: :..: :: .:.:.:: .::.:::. ::: ::  :.
NP_009 LYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL
              130       140       150       160       170       180

       160       170  
pF1KB0 GGLDIHKKMVVDV  
         .:...:: .    
NP_009 EKVDVEQKMSIRFLH
              190     




170 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 17:52:57 2016 done: Sat Nov  5 17:52:58 2016
 Total Scan time:  5.260 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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