Result of FASTA (omim) for pF1KB0994
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0994, 461 aa
  1>>>pF1KB0994 461 - 461 aa - 461 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8710+/-0.000345; mu= 16.3634+/- 0.021
 mean_var=124.0234+/-25.918, 0's: 0 Z-trim(116.9): 156  B-trim: 119 in 1/52
 Lambda= 0.115166
 statistics sampled from 28277 (28504) to 28277 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.334), width:  16
 Scan time:  9.970

The best scores are:                                      opt bits E(85289)
NP_009005 (OMIM: 605000,615401) coronin-1A [Homo s ( 461) 3136 532.5 9.4e-151
NP_001180262 (OMIM: 605000,615401) coronin-1A [Hom ( 461) 3136 532.5 9.4e-151
XP_011544016 (OMIM: 605000,615401) PREDICTED: coro ( 461) 3136 532.5 9.4e-151
XP_016878374 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140
XP_016878375 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140
NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] ( 489) 2190 375.3  2e-103
NP_001018080 (OMIM: 609849) coronin-1B [Homo sapie ( 489) 2190 375.3  2e-103
NP_055140 (OMIM: 605269) coronin-1C isoform b [Hom ( 474) 2155 369.5 1.1e-101
XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C  ( 474) 2155 369.5 1.1e-101
XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C  ( 474) 2155 369.5 1.1e-101
NP_001263400 (OMIM: 605269) coronin-1C isoform b [ ( 474) 2155 369.5 1.1e-101
XP_016874610 (OMIM: 605269) PREDICTED: coronin-1C  ( 527) 2155 369.5 1.2e-101
NP_001098707 (OMIM: 605269) coronin-1C isoform a [ ( 527) 2155 369.5 1.2e-101
NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63
NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 1381 240.9 5.8e-63
NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61
NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61
XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A  ( 525) 1349 235.6 2.5e-61
XP_011536427 (OMIM: 605269) PREDICTED: coronin-1C  ( 286) 1046 185.0 2.3e-46
NP_078811 (OMIM: 611668) coronin-7 isoform 1 [Homo ( 925)  740 134.7   1e-30
NP_001188401 (OMIM: 611668) coronin-7 isoform 2 [H ( 907)  648 119.4 4.1e-26
NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840)  538 101.1 1.2e-20
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  194 43.5  0.0011
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  194 43.5  0.0011
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  194 43.5  0.0011
XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982)  199 44.8  0.0012
NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351)  192 43.2  0.0014
XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216)  199 44.9  0.0014
NP_851782 (OMIM: 609005) WD repeat-containing prot (1283)  199 45.0  0.0015
XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290)  199 45.0  0.0015
XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307)  199 45.0  0.0015
XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314)  199 45.0  0.0015
XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314)  199 45.0  0.0015
NP_733828 (OMIM: 609005) WD repeat-containing prot (1322)  199 45.0  0.0015
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579)  192 43.4  0.0019
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504)  190 43.0  0.0022
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301)  182 41.4  0.0039
XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353)  182 41.5  0.0044
NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353)  182 41.5  0.0044
NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395)  182 41.6  0.0047
XP_005258020 (OMIM: 610091) PREDICTED: WD repeat a ( 216)  178 40.6   0.005
XP_016879923 (OMIM: 610091) PREDICTED: WD repeat a ( 216)  178 40.6   0.005
NP_004795 (OMIM: 604333) probable cytosolic iron-s ( 339)  178 40.8  0.0068


>>NP_009005 (OMIM: 605000,615401) coronin-1A [Homo sapie  (461 aa)
 initn: 3136 init1: 3136 opt: 3136  Z-score: 2827.5  bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
              370       380       390       400       410       420

              430       440       450       460 
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
       :::::::::::::::::::::::::::::::::::::::::
NP_009 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
              430       440       450       460 

>>NP_001180262 (OMIM: 605000,615401) coronin-1A [Homo sa  (461 aa)
 initn: 3136 init1: 3136 opt: 3136  Z-score: 2827.5  bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
              370       380       390       400       410       420

              430       440       450       460 
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
       :::::::::::::::::::::::::::::::::::::::::
NP_001 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
              430       440       450       460 

>>XP_011544016 (OMIM: 605000,615401) PREDICTED: coronin-  (461 aa)
 initn: 3136 init1: 3136 opt: 3136  Z-score: 2827.5  bits: 532.5 E(85289): 9.4e-151
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
              370       380       390       400       410       420

              430       440       450       460 
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
       :::::::::::::::::::::::::::::::::::::::::
XP_011 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
              430       440       450       460 

>>XP_016878374 (OMIM: 605000,615401) PREDICTED: coronin-  (463 aa)
 initn: 2933 init1: 2933 opt: 2933  Z-score: 2645.2  bits: 498.7 E(85289): 1.3e-140
Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
              370       380       390       400       410       420

              430       440       450       460   
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK  
       :::::::                                    
XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW
              430       440       450       460   

>>XP_016878375 (OMIM: 605000,615401) PREDICTED: coronin-  (463 aa)
 initn: 2933 init1: 2933 opt: 2933  Z-score: 2645.2  bits: 498.7 E(85289): 1.3e-140
Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE
              370       380       390       400       410       420

              430       440       450       460   
pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK  
       :::::::                                    
XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW
              430       440       450       460   

>>NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens]      (489 aa)
 initn: 2244 init1: 1235 opt: 2190  Z-score: 1977.7  bits: 375.3 E(85289): 2e-103
Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479)

                10        20        30        40        50         
pF1KB0  MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF
          :.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: ::::::::
NP_065 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP
       :::::.::::.::  :::::::.::::: ::::::.::::::::::::::.::..::  :
NP_065 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI
       : ::::.::::::::::.::: ::.:::::::::::...:.:::.  .  :   .::: :
NP_065 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI
              130       140       150       160       170          

     180       190       200       210       220       230         
pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF
       :.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..::::
NP_065 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS
       :::::::.:::: ..::::..:::::.:.:.::::.::::..::.:::::::::::::: 
NP_065 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE
     240       250       260       270       280       290         

     300       310       320       330       340       350         
pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF
       : :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.::::::::::
NP_065 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF
     300       310       320       330       340       350         

     360       370       380       390       400         410       
pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA
       :.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...:   :. .:   
NP_065 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM
     360       370       380       390       400       410         

       420              430                     440       450      
pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE
       :: .:  :.:.:     ::.           ..:::   :.: :.: :.:   :. ::::
NP_065 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE
     420       430       440       450       460       470         

        460      
pF1KB0 TVQAK     
                 
NP_065 QLGRMENGDA
     480         

>>NP_001018080 (OMIM: 609849) coronin-1B [Homo sapiens]   (489 aa)
 initn: 2244 init1: 1235 opt: 2190  Z-score: 1977.7  bits: 375.3 E(85289): 2e-103
Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479)

                10        20        30        40        50         
pF1KB0  MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF
          :.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: ::::::::
NP_001 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP
       :::::.::::.::  :::::::.::::: ::::::.::::::::::::::.::..::  :
NP_001 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI
       : ::::.::::::::::.::: ::.:::::::::::...:.:::.  .  :   .::: :
NP_001 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI
              130       140       150       160       170          

     180       190       200       210       220       230         
pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF
       :.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..::::
NP_001 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS
       :::::::.:::: ..::::..:::::.:.:.::::.::::..::.:::::::::::::: 
NP_001 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE
     240       250       260       270       280       290         

     300       310       320       330       340       350         
pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF
       : :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.::::::::::
NP_001 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF
     300       310       320       330       340       350         

     360       370       380       390       400         410       
pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA
       :.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...:   :. .:   
NP_001 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM
     360       370       380       390       400       410         

       420              430                     440       450      
pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE
       :: .:  :.:.:     ::.           ..:::   :.: :.: :.:   :. ::::
NP_001 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE
     420       430       440       450       460       470         

        460      
pF1KB0 TVQAK     
                 
NP_001 QLGRMENGDA
     480         

>>NP_055140 (OMIM: 605269) coronin-1C isoform b [Homo sa  (474 aa)
 initn: 2181 init1: 1198 opt: 2155  Z-score: 1946.4  bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
         :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
NP_055  MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
NP_055 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
        :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...:  ..: : ::
NP_055 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       .:.:.:.:.::::. .::.::.:.:::  .::::.. :::.::.::.:...:...:::::
NP_055 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
NP_055 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
NP_055 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
      300       310       320       330       340       350        

              370       380       390       400         410        
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
       .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: .   ::   :. .
NP_055 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
      360       370       380       390       400       410        

             420        430          440       450       460   
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK  
       .    . :. .. : : .  ..:.:   :..... :. . ..:...::.       
NP_055 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
      420       430       440       450       460       470    

>>XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C isof  (474 aa)
 initn: 2181 init1: 1198 opt: 2155  Z-score: 1946.4  bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
         :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
XP_016  MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
        :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...:  ..: : ::
XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       .:.:.:.:.::::. .::.::.:.:::  .::::.. :::.::.::.:...:...:::::
XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
      300       310       320       330       340       350        

              370       380       390       400         410        
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
       .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: .   ::   :. .
XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
      360       370       380       390       400       410        

             420        430          440       450       460   
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK  
       .    . :. .. : : .  ..:.:   :..... :. . ..:...::.       
XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
      420       430       440       450       460       470    

>>XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C isof  (474 aa)
 initn: 2181 init1: 1198 opt: 2155  Z-score: 1946.4  bits: 369.5 E(85289): 1.1e-101
Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467)

               10        20        30        40        50        60
pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL
         :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: :::::::::
XP_016  MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL
       :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : :
XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY
        :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...:  ..: : ::
XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS
       .:.:.:.:.::::. .::.::.:.:::  .::::.. :::.::.::.:...:...:::::
XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE
       ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.:
XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ
       .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: :::::::::::
XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ
      300       310       320       330       340       350        

              370       380       390       400         410        
pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR
       .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: .   ::   :. .
XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK
      360       370       380       390       400       410        

             420        430          440       450       460   
pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK  
       .    . :. .. : : .  ..:.:   :..... :. . ..:...::.       
XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA
      420       430       440       450       460       470    




461 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 17:43:32 2016 done: Sat Nov  5 17:43:33 2016
 Total Scan time:  9.970 Total Display time:  0.100

Function used was FASTA [36.3.4 Apr, 2011]
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