Result of FASTA (omim) for pF1KB6523
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6523, 364 aa
  1>>>pF1KB6523 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.4825+/-0.000317; mu= 8.8765+/- 0.020
 mean_var=230.6675+/-50.921, 0's: 0 Z-trim(122.8): 91  B-trim: 2195 in 1/58
 Lambda= 0.084446
 statistics sampled from 41425 (41578) to 41425 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.487), width:  16
 Scan time:  9.010

The best scores are:                                      opt bits E(85289)
NP_659501 (OMIM: 255995,615521) SH3 and cysteine-r ( 364) 2515 318.8 1.2e-86
XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3  ( 364) 2515 318.8 1.2e-86
NP_001273185 (OMIM: 255995,615521) SH3 and cystein ( 325) 2269 288.8 1.2e-77
NP_001273186 (OMIM: 255995,615521) SH3 and cystein ( 178) 1214 159.9 3.9e-39
XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cys ( 215)  431 64.7 2.3e-10
XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cys ( 334)  431 64.9   3e-10
XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cys ( 334)  431 64.9   3e-10
NP_001278978 (OMIM: 602317) SH3 and cysteine-rich  ( 341)  431 64.9 3.1e-10
XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cys ( 391)  431 65.0 3.3e-10
NP_003140 (OMIM: 602317) SH3 and cysteine-rich dom ( 402)  431 65.0 3.4e-10
XP_011532338 (OMIM: 602317) PREDICTED: SH3 and cys ( 406)  431 65.0 3.4e-10


>>NP_659501 (OMIM: 255995,615521) SH3 and cysteine-rich   (364 aa)
 initn: 2515 init1: 2515 opt: 2515  Z-score: 1676.6  bits: 318.8 E(85289): 1.2e-86
Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)

               10        20        30        40        50        60
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
              310       320       330       340       350       360

           
pF1KB6 LEEI
       ::::
NP_659 LEEI
           

>>XP_011536428 (OMIM: 255995,615521) PREDICTED: SH3 and   (364 aa)
 initn: 2515 init1: 2515 opt: 2515  Z-score: 1676.6  bits: 318.8 E(85289): 1.2e-86
Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)

               10        20        30        40        50        60
pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
              310       320       330       340       350       360

           
pF1KB6 LEEI
       ::::
XP_011 LEEI
           

>>NP_001273185 (OMIM: 255995,615521) SH3 and cysteine-ri  (325 aa)
 initn: 2269 init1: 2269 opt: 2269  Z-score: 1515.2  bits: 288.8 E(85289): 1.2e-77
Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 325 aa overlap (40-364:1-325)

      10        20        30        40        50        60         
pF1KB6 PKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEE
                                     ::::::::::::::::::::::::::::::
NP_001                               MELPPEPQANGEAVGAGGGPIYYIYEEEEE
                                             10        20        30

      70        80        90       100       110       120         
pF1KB6 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KB6 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KB6 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KB6 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER
              220       230       240       250       260       270

     310       320       330       340       350       360    
pF1KB6 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
              280       290       300       310       320     

>>NP_001273186 (OMIM: 255995,615521) SH3 and cysteine-ri  (178 aa)
 initn: 1214 init1: 1214 opt: 1214  Z-score: 823.6  bits: 159.9 E(85289): 3.9e-39
Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 178 aa overlap (187-364:1-178)

        160       170       180       190       200       210      
pF1KB6 YSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARP
                                     ::::::::::::::::::::::::::::::
NP_001                               MANKERKKGQADKKNPVAAMMEEEPESARP
                                             10        20        30

        220       230       240       250       260       270      
pF1KB6 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
               40        50        60        70        80        90

        280       290       300       310       320       330      
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
              100       110       120       130       140       150

        340       350       360    
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
       ::::::::::::::::::::::::::::
NP_001 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
              160       170        

>>XP_016862573 (OMIM: 602317) PREDICTED: SH3 and cystein  (215 aa)
 initn: 475 init1: 417 opt: 431  Z-score: 307.1  bits: 64.7 E(85289): 2.3e-10
Smith-Waterman score: 478; 36.0% identity (67.3% similar) in 214 aa overlap (168-364:3-215)

       140       150       160       170       180       190       
pF1KB6 QRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERK----
                                     .. .:. :::.:::: :. .:.. .:    
XP_016                             MPIACGNKVDPVYETLRFGTSLAQRTKKGSSG
                                           10        20        30  

           200       210       220                    230       240
pF1KB6 KGQADKKNPVAAMMEEEPESARPEEGK-------------PQDGNPEGDKKAEKKTPDDK
       .:. . .   .. . : :: :    :              :..:. .    :.. . . .
XP_016 SGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGS
             40        50        60        70        80        90  

              250       260       270       280       290       300
pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF
        ..  .:.. : ::::.:   :..::.. ::. ::...::::.::.::: ...:::: ::
XP_016 LSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANF
            100        110       120       130       140       150 

              310       320       330       340       350       360
pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF
       . :.. .:.. : .:.:.: .: ::::::..:: :.. .:  :...: .:.: ::.: : 
XP_016 VQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDV
             160       170       180       190       200       210 

           
pF1KB6 LEEI
       ::.:
XP_016 LENI
           

>>XP_016862572 (OMIM: 602317) PREDICTED: SH3 and cystein  (334 aa)
 initn: 773 init1: 417 opt: 431  Z-score: 304.9  bits: 64.9 E(85289): 3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:38-334)

        60        70        80        90       100       110       
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
                                     : : :....:::: ::::: .:::  : : 
XP_016 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
        10        20        30        40        50        60       

        120       130       140       150       160          170   
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
       ::::: :: .::..: . .  :::.::.: ::.: :::::  ..:..:.:.   .. .:.
XP_016 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
        70        80        90       100       110       120       

           180       190           200       210       220         
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
        :::.:::: :. .:.. .:    .:. . .   .. . : :: :    :          
XP_016 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
       130       140       150       160       170       180       

                  230       240       250       260       270      
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
           :..:. .    :.. . . . ..  .:.. : ::::.:   :..::.. ::. ::.
XP_016 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
       190       200       210       220        230       240      

        280       290       300       310       320       330      
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
       ..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_016 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
        250       260       270       280       290       300      

        340       350       360    
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
       . .:  :...: .:.: ::.: : ::.:
XP_016 SEEEQDGFIRVLSGKKKGLIPLDVLENI
        310       320       330    

>>XP_011532340 (OMIM: 602317) PREDICTED: SH3 and cystein  (334 aa)
 initn: 773 init1: 417 opt: 431  Z-score: 304.9  bits: 64.9 E(85289): 3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:38-334)

        60        70        80        90       100       110       
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
                                     : : :....:::: ::::: .:::  : : 
XP_011 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
        10        20        30        40        50        60       

        120       130       140       150       160          170   
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
       ::::: :: .::..: . .  :::.::.: ::.: :::::  ..:..:.:.   .. .:.
XP_011 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
        70        80        90       100       110       120       

           180       190           200       210       220         
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
        :::.:::: :. .:.. .:    .:. . .   .. . : :: :    :          
XP_011 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
       130       140       150       160       170       180       

                  230       240       250       260       270      
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
           :..:. .    :.. . . . ..  .:.. : ::::.:   :..::.. ::. ::.
XP_011 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
       190       200       210       220        230       240      

        280       290       300       310       320       330      
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
       ..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_011 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
        250       260       270       280       290       300      

        340       350       360    
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
       . .:  :...: .:.: ::.: : ::.:
XP_011 SEEEQDGFIRVLSGKKKGLIPLDVLENI
        310       320       330    

>>NP_001278978 (OMIM: 602317) SH3 and cysteine-rich doma  (341 aa)
 initn: 581 init1: 417 opt: 431  Z-score: 304.8  bits: 64.9 E(85289): 3.1e-10
Smith-Waterman score: 490; 28.9% identity (52.8% similar) in 388 aa overlap (4-364:17-341)

                            10        20        30        40       
pF1KB6              MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ
                       ::.. . .:  :: : .:  ..:..: :. :  :: ..     .
NP_001 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK
               10        20        30         40        50         

        50        60        70        80                  90       
pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF
       .  .     ..  . .  .   :      : : : .:..           : : :....:
NP_001 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF
          60        70        80        90       100       110     

       100       110       120       130       140       150       
pF1KB6 KKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLY
       ::: ::::: .:::                                              
NP_001 KKPTFCDVCNHMIV----------------------------------------------
         120                                                       

       160       170       180       190           200       210   
pF1KB6 SNQQYACVKDLSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPES
            ::      .:. :::.:::: :. .:.. .:    .:. . .   .. . : :: 
NP_001 -----AC------GNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEE
          130             140       150       160       170        

           220                    230       240       250       260
pF1KB6 ARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKA
       :    :              :..:. .    :.. . . . ..  .:.. : ::::.:  
NP_001 ANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVP
      180       190       200       210       220        230       

              270       280       290       300       310       320
pF1KB6 LEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGN
        :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:.:.: 
NP_001 QENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGC
       240       250       260       270       280       290       

              330       340       350       360    
pF1KB6 REIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
       .: ::::::..:: :.. .:  :...: .:.: ::.: : ::.:
NP_001 KEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
       300       310       320       330       340 

>>XP_011532339 (OMIM: 602317) PREDICTED: SH3 and cystein  (391 aa)
 initn: 773 init1: 417 opt: 431  Z-score: 304.1  bits: 65.0 E(85289): 3.3e-10
Smith-Waterman score: 799; 40.6% identity (69.5% similar) in 298 aa overlap (88-364:95-391)

        60        70        80        90       100       110       
pF1KB6 GPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIV-LNNKF
                                     : : :....:::: ::::: .:::  : : 
XP_011 VAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHMIVGTNAKH
           70        80        90       100       110       120    

        120       130       140       150       160          170   
pF1KB6 GLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKD---LSAANR
       ::::: :: .::..: . .  :::.::.: ::.: :::::  ..:..:.:.   .. .:.
XP_011 GLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNK
          130       140       150       160       170       180    

           180       190           200       210       220         
pF1KB6 NDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPESARPEEGK---------
        :::.:::: :. .:.. .:    .:. . .   .. . : :: :    :          
XP_011 VDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEANGPGGGYDLRKRSNS
          190       200       210       220       230       240    

                  230       240       250       260       270      
pF1KB6 ----PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV
           :..:. .    :.. . . . ..  .:.. : ::::.:   :..::.. ::. ::.
XP_011 VFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVPQENEDLEMRPGDIITL
          250       260       270        280       290       300   

        280       290       300       310       320       330      
pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ
       ..::::.::.::: ...:::: ::. :.. .:.. : .:.:.: .: ::::::..:: :.
XP_011 LEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVS
           310       320       330       340       350       360   

        340       350       360    
pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI
       . .:  :...: .:.: ::.: : ::.:
XP_011 SEEEQDGFIRVLSGKKKGLIPLDVLENI
           370       380       390 

>>NP_003140 (OMIM: 602317) SH3 and cysteine-rich domain-  (402 aa)
 initn: 773 init1: 417 opt: 431  Z-score: 304.0  bits: 65.0 E(85289): 3.4e-10
Smith-Waterman score: 809; 35.5% identity (63.3% similar) in 392 aa overlap (4-364:17-402)

                            10        20        30        40       
pF1KB6              MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ
                       ::.. . .:  :: : .:  ..:..: :. :  :: ..     .
NP_003 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK
               10        20        30         40        50         

        50        60        70        80                  90       
pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF
       .  .     ..  . .  .   :      : : : .:..           : : :....:
NP_003 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF
          60        70        80        90       100       110     

       100       110        120       130       140       150      
pF1KB6 KKPKFCDVCARMIV-LNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPL
       ::: ::::: .:::  : : ::::: :: .::..: . .  :::.::.: ::.: :::::
NP_003 KKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPL
         120       130       140       150       160       170     

        160          170       180       190           200         
pF1KB6 YSNQQYACVKD---LSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEE
         ..:..:.:.   .. .:. :::.:::: :. .:.. .:    .:. . .   .. . :
NP_003 LIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVE
         180       190       200       210       220       230     

     210       220                    230       240       250      
pF1KB6 EPESARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALY
        :: :    :              :..:. .    :.. . . . ..  .:.. : ::::
NP_003 VPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALY
         240       250       260       270       280       290     

        260       270       280       290       300       310      
pF1KB6 RFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRS
       .:   :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:.
NP_003 KFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRT
          300       310       320       330       340       350    

        320       330       340       350       360    
pF1KB6 FVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
       :.: .: ::::::..:: :.. .:  :...: .:.: ::.: : ::.:
NP_003 FIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
          360       370       380       390       400  




364 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:53:55 2016 done: Sat Nov  5 16:53:56 2016
 Total Scan time:  9.010 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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