Result of FASTA (omim) for pF1KB8560
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8560, 910 aa
  1>>>pF1KB8560 910 - 910 aa - 910 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1925+/-0.000404; mu= 21.8786+/- 0.025
 mean_var=68.1225+/-13.474, 0's: 0 Z-trim(111.1): 252  B-trim: 58 in 1/53
 Lambda= 0.155392
 statistics sampled from 19414 (19668) to 19414 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.231), width:  16
 Scan time: 13.290

The best scores are:                                      opt bits E(85289)
NP_036547 (OMIM: 604289,605027) DNA repair and rec ( 910) 6121 1382.0       0
NP_001192192 (OMIM: 604289,605027) DNA repair and  ( 726) 4889 1105.7       0
NP_003570 (OMIM: 114480,603615,605027) DNA repair  ( 747) 1045 244.0 2.1e-63
NP_001136020 (OMIM: 114480,603615,605027) DNA repa ( 747) 1045 244.0 2.1e-63
XP_006711038 (OMIM: 114480,603615,605027) PREDICTE ( 567)  850 200.2 2.4e-50
NP_001192191 (OMIM: 604289,605027) DNA repair and  ( 117)  697 165.5 1.4e-40
XP_011540601 (OMIM: 114480,603615,605027) PREDICTE ( 489)  699 166.3 3.3e-40
XP_011540602 (OMIM: 114480,603615,605027) PREDICTE ( 489)  699 166.3 3.3e-40
NP_000115 (OMIM: 133540,211980,214150,278800,60063 (1493)  485 118.6 2.2e-25
NP_001333369 (OMIM: 133540,211980,214150,278800,60 (1493)  485 118.6 2.2e-25
NP_060139 (OMIM: 300687) DNA excision repair prote (1250)  476 116.6 7.9e-25
XP_016872369 (OMIM: 605191) PREDICTED: TATA-bindin (1519)  476 116.6 9.2e-25
XP_016872370 (OMIM: 605191) PREDICTED: TATA-bindin (1519)  476 116.6 9.2e-25
XP_016872368 (OMIM: 605191) PREDICTED: TATA-bindin (1519)  476 116.6 9.2e-25
XP_016885240 (OMIM: 300012) PREDICTED: probable gl (1036)  474 116.1 9.2e-25
XP_016885239 (OMIM: 300012) PREDICTED: probable gl (1042)  474 116.1 9.3e-25
XP_006724845 (OMIM: 300012) PREDICTED: probable gl (1042)  474 116.1 9.3e-25
NP_001269804 (OMIM: 300012) probable global transc (1058)  474 116.1 9.4e-25
XP_016872367 (OMIM: 605191) PREDICTED: TATA-bindin (1646)  476 116.6 9.8e-25
XP_011538630 (OMIM: 605191) PREDICTED: TATA-bindin (1693)  476 116.7   1e-24
XP_011538629 (OMIM: 605191) PREDICTED: TATA-bindin (1725)  476 116.7   1e-24
XP_016872366 (OMIM: 605191) PREDICTED: TATA-bindin (1800)  476 116.7 1.1e-24
XP_011538628 (OMIM: 605191) PREDICTED: TATA-bindin (1812)  476 116.7 1.1e-24
NP_003963 (OMIM: 605191) TATA-binding protein-asso (1849)  476 116.7 1.1e-24
NP_001275998 (OMIM: 603946,616911) lymphoid-specif ( 806)  452 111.1 2.3e-23
XP_011516946 (OMIM: 615667,615715) PREDICTED: DNA  (1263)  444 109.4 1.1e-22
NP_003592 (OMIM: 603375) SWI/SNF-related matrix-as (1052)  426 105.3 1.6e-21
NP_001010895 (OMIM: 615667,615715) DNA excision re ( 712)  404 100.3 3.6e-20
XP_011516949 (OMIM: 615667,615715) PREDICTED: DNA  (1178)  404 100.4 5.4e-20
XP_011516948 (OMIM: 615667,615715) PREDICTED: DNA  (1184)  404 100.4 5.4e-20
XP_011516947 (OMIM: 615667,615715) PREDICTED: DNA  (1253)  404 100.4 5.7e-20
XP_011516943 (OMIM: 615667,615715) PREDICTED: DNA  (1510)  404 100.5 6.6e-20
NP_064592 (OMIM: 615667,615715) DNA excision repai (1561)  404 100.5 6.8e-20
NP_001276004 (OMIM: 603946,616911) lymphoid-specif ( 432)  391 97.2 1.8e-19
NP_001276003 (OMIM: 603946,616911) lymphoid-specif ( 477)  391 97.2   2e-19
NP_001276002 (OMIM: 603946,616911) lymphoid-specif ( 700)  391 97.4 2.7e-19
NP_001276001 (OMIM: 603946,616911) lymphoid-specif ( 708)  391 97.4 2.7e-19
NP_001276000 (OMIM: 603946,616911) lymphoid-specif ( 714)  391 97.4 2.7e-19
NP_001275999 (OMIM: 603946,616911) lymphoid-specif ( 740)  391 97.4 2.8e-19
NP_001275997 (OMIM: 603946,616911) lymphoid-specif ( 822)  391 97.4 3.1e-19
NP_060533 (OMIM: 603946,616911) lymphoid-specific  ( 838)  391 97.4 3.1e-19
XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892)  395 98.5 3.2e-19
XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893)  395 98.5 3.2e-19
XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895)  395 98.5 3.2e-19
XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899)  395 98.5 3.2e-19
XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900)  395 98.5 3.2e-19
XP_006719025 (OMIM: 603277,617159) PREDICTED: chro (1902)  395 98.5 3.2e-19
XP_005253725 (OMIM: 603277,617159) PREDICTED: chro (1905)  395 98.5 3.2e-19
NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905)  395 98.5 3.2e-19
XP_016874218 (OMIM: 603277,617159) PREDICTED: chro (1906)  395 98.5 3.2e-19


>>NP_036547 (OMIM: 604289,605027) DNA repair and recombi  (910 aa)
 initn: 6121 init1: 6121 opt: 6121  Z-score: 7408.2  bits: 1382.0 E(85289):    0
Smith-Waterman score: 6121; 100.0% identity (100.0% similar) in 910 aa overlap (1-910:1-910)

               10        20        30        40        50        60
pF1KB8 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 KENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 KEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 VTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 KNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 ILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 PKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 SIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 EKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 KAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB8 RQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGD
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB8 SLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIF
              850       860       870       880       890       900

              910
pF1KB8 QNITTQATGT
       ::::::::::
NP_036 QNITTQATGT
              910

>>NP_001192192 (OMIM: 604289,605027) DNA repair and reco  (726 aa)
 initn: 4889 init1: 4889 opt: 4889  Z-score: 5916.9  bits: 1105.7 E(85289):    0
Smith-Waterman score: 4889; 100.0% identity (100.0% similar) in 726 aa overlap (185-910:1-726)

          160       170       180       190       200       210    
pF1KB8 ILKNLEGKDIGRGIGYKFKELEKIEEGQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGS
                                     ::::::::::::::::::::::::::::::
NP_001                               MICGKEIEVMGVISPDDFSSGRCFQLGGGS
                                             10        20        30

          220       230       240       250       260       270    
pF1KB8 TAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQW
               40        50        60        70        80        90

          280       290       300       310       320       330    
pF1KB8 VFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTL
              100       110       120       130       140       150

          340       350       360       370       380       390    
pF1KB8 QCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKV
              160       170       180       190       200       210

          400       410       420       430       440       450    
pF1KB8 EEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEK
              220       230       240       250       260       270

          460       470       480       490       500       510    
pF1KB8 RIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGER
              280       290       300       310       320       330

          520       530       540       550       560       570    
pF1KB8 RAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQG
              340       350       360       370       380       390

          580       590       600       610       620       630    
pF1KB8 LLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPL
              400       410       420       430       440       450

          640       650       660       670       680       690    
pF1KB8 LFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQT
              460       470       480       490       500       510

          700       710       720       730       740       750    
pF1KB8 PISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRV
              520       530       540       550       560       570

          760       770       780       790       800       810    
pF1KB8 WRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFT
              580       590       600       610       620       630

          820       830       840       850       860       870    
pF1KB8 LHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQW
              640       650       660       670       680       690

          880       890       900       910
pF1KB8 KHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
       ::::::::::::::::::::::::::::::::::::
NP_001 KHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
              700       710       720      

>>NP_003570 (OMIM: 114480,603615,605027) DNA repair and   (747 aa)
 initn: 1572 init1: 554 opt: 1045  Z-score: 1259.4  bits: 244.0 E(85289): 2.1e-63
Smith-Waterman score: 1673; 43.1% identity (66.8% similar) in 708 aa overlap (218-901:68-736)

       190       200       210       220       230       240       
pF1KB8 GKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKE---NR
                                     :.     :. .:.::: :  :. .    .:
NP_003 SSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFK-VPIPNYQGPLGSR
        40        50        60        70        80         90      

          250          260         270        280       290        
pF1KB8 QNDFQNCKPR---HDPYTPNSLVM--PRPDKNH-QWVFNKNCFPLVDVVIDPYLVYHLRP
          ..    :   :::   ..::.  : : . : :  ..:. .: : ::.:: :   :::
NP_003 ALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLP-VHVVVDPILSKVLRP
        100       110       120       130       140        150     

      300       310       320       330       340       350        
pF1KB8 HQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKT
       ::.::. ::.::: . :. :  : :.:::::::::::::.:.:::  :.:   :: : :.
NP_003 HQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPEC-KPEIDKA
         160       170       180       190       200        210    

      360       370       380       390             400            
pF1KB8 LIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFYSVLII
       ..:.:.:::.:: .:  ::::. ::. ...:       :.:.: :...    .   .:::
NP_003 VVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILII
          220       230        240       250       260       270   

      410       420       430       440       450       460        
pF1KB8 SYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQ
       ::: .   .  ... .  :.:::::::::::  .:  :: ::.  .:....:::::::: 
NP_003 SYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLL
           280       290       300       310       320       330   

      470       480       490       500       510       520        
pF1KB8 EFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFIL
       :.:.:. ::: ::::.   ..: .: ::. .:. .::: ...:::.:  ::: ...  ..
NP_003 EYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLI
           340       350       360       370       380       390   

      530       540       550       560        570       580       
pF1KB8 RRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHLICIGA
       :::..:..:::: :::.:: ::   :: :::...: ... ..  :.: .  :  :  : .
NP_003 RRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-LSSITS
           400       410       420       430       440        450  

       590       600       610       620       630       640       
pF1KB8 LKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVL
       :::::::: :...     .:       ::.. . : :..::  :.   .  . :::. ::
NP_003 LKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVL
            460                  470       480       490       500 

       650       660       670       680       690       700       
pF1KB8 SKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFN
       . .::: .  : ..::::::::::::......:. . : :.::::   :..: ..:. ::
NP_003 DYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFN
             510        520       530       540       550       560

       710       720       730       740       750       760       
pF1KB8 SQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYR
       :  :  :.:.::::::: ::::::...:...: :::::.: :::.::::::::   .:::
NP_003 SPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYR
              570       580       590       600       610       620

       770       780       790       800       810       820       
pF1KB8 LLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLL
       ::..:::::::.:::  :..: . :::  .  :. .::. :::.:: : :.:   ::: :
NP_003 LLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSDTHDRL
              630       640       650        660       670         

       830       840       850       860       870       880       
pF1KB8 DCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDP
        :.             . . ::  :. :  . :.       :.:  :.: . :. .: : 
NP_003 HCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKWGLRDE
     680                      690       700            710         

       890           900       910  
pF1KB8 FLERI----TENVSFIFQNITTQATGT  
        :.      .  ..:.:.           
NP_003 VLQAAWDAASTAITFVFHQRSHEEQRGLR
      720       730       740       

>>NP_001136020 (OMIM: 114480,603615,605027) DNA repair a  (747 aa)
 initn: 1572 init1: 554 opt: 1045  Z-score: 1259.4  bits: 244.0 E(85289): 2.1e-63
Smith-Waterman score: 1673; 43.1% identity (66.8% similar) in 708 aa overlap (218-901:68-736)

       190       200       210       220       230       240       
pF1KB8 GKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKE---NR
                                     :.     :. .:.::: :  :. .    .:
NP_001 SSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFK-VPIPNYQGPLGSR
        40        50        60        70        80         90      

          250          260         270        280       290        
pF1KB8 QNDFQNCKPR---HDPYTPNSLVM--PRPDKNH-QWVFNKNCFPLVDVVIDPYLVYHLRP
          ..    :   :::   ..::.  : : . : :  ..:. .: : ::.:: :   :::
NP_001 ALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLP-VHVVVDPILSKVLRP
        100       110       120       130       140        150     

      300       310       320       330       340       350        
pF1KB8 HQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKT
       ::.::. ::.::: . :. :  : :.:::::::::::::.:.:::  :.:   :: : :.
NP_001 HQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPEC-KPEIDKA
         160       170       180       190       200        210    

      360       370       380       390             400            
pF1KB8 LIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFYSVLII
       ..:.:.:::.:: .:  ::::. ::. ...:       :.:.: :...    .   .:::
NP_001 VVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILII
          220       230        240       250       260       270   

      410       420       430       440       450       460        
pF1KB8 SYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQ
       ::: .   .  ... .  :.:::::::::::  .:  :: ::.  .:....:::::::: 
NP_001 SYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLL
           280       290       300       310       320       330   

      470       480       490       500       510       520        
pF1KB8 EFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFIL
       :.:.:. ::: ::::.   ..: .: ::. .:. .::: ...:::.:  ::: ...  ..
NP_001 EYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLI
           340       350       360       370       380       390   

      530       540       550       560        570       580       
pF1KB8 RRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHLICIGA
       :::..:..:::: :::.:: ::   :: :::...: ... ..  :.: .  :  :  : .
NP_001 RRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-LSSITS
           400       410       420       430       440        450  

       590       600       610       620       630       640       
pF1KB8 LKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVL
       :::::::: :...     .:       ::.. . : :..::  :.   .  . :::. ::
NP_001 LKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVL
            460                  470       480       490       500 

       650       660       670       680       690       700       
pF1KB8 SKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFN
       . .::: .  : ..::::::::::::......:. . : :.::::   :..: ..:. ::
NP_001 DYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFN
             510        520       530       540       550       560

       710       720       730       740       750       760       
pF1KB8 SQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYR
       :  :  :.:.::::::: ::::::...:...: :::::.: :::.::::::::   .:::
NP_001 SPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYR
              570       580       590       600       610       620

       770       780       790       800       810       820       
pF1KB8 LLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLL
       ::..:::::::.:::  :..: . :::  .  :. .::. :::.:: : :.:   ::: :
NP_001 LLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSDTHDRL
              630       640       650        660       670         

       830       840       850       860       870       880       
pF1KB8 DCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDP
        :.             . . ::  :. :  . :.       :.:  :.: . :. .: : 
NP_001 HCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKWGLRDE
     680                      690       700            710         

       890           900       910  
pF1KB8 FLERI----TENVSFIFQNITTQATGT  
        :.      .  ..:.:.           
NP_001 VLQAAWDAASTAITFVFHQRSHEEQRGLR
      720       730       740       

>>XP_006711038 (OMIM: 114480,603615,605027) PREDICTED: D  (567 aa)
 initn: 1445 init1: 554 opt: 850  Z-score: 1024.9  bits: 200.2 E(85289): 2.4e-50
Smith-Waterman score: 1478; 44.2% identity (68.6% similar) in 593 aa overlap (324-901:1-556)

           300       310       320       330       340       350   
pF1KB8 YHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKP
                                     .:::::::::::::.:.:::  :.:   ::
XP_006                               MADEMGLGKTLQCITLMWTLLRQSPEC-KP
                                             10        20          

           360       370       380       390             400       
pF1KB8 VIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQ------DHKVEEFIKS----IFY
        : :...:.:.:::.:: .:  ::::. ::. ...:       :.:.: :...    .  
XP_006 EIDKAVVVSPSSLVKNWYNEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGFMNQRGARVSS
      30        40        50         60        70        80        

           410       420       430       440       450       460   
pF1KB8 SVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPI
        .:::::: .   .  ... .  :.:::::::::::  .:  :: ::.  .:....::::
XP_006 PILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPI
       90       100       110       120       130       140        

           470       480       490       500       510       520   
pF1KB8 QNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLT
       :::: :.:.:. ::: ::::.   ..: .: ::. .:. .::: ...:::.:  ::: ..
XP_006 QNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIV
      150       160       170       180       190       200        

           530       540       550       560        570       580  
pF1KB8 GLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLL-NSQVVRFCLQGLLENSPHL
       .  ..:::..:..:::: :::.:: ::   :: :::...: ... ..  :.: .  :  :
XP_006 NRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSS-L
      210       220       230       240       250       260        

            590       600       610       620       630       640  
pF1KB8 ICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESG
         : .:::::::: :...     .:       ::.. . : :..::  :.   .  . ::
XP_006 SSITSLKKLCNHPALIYD-----KCV------EEEDGFVGALDLFPPGYSSKALEPQLSG
       270       280                  290       300       310      

            650       660       670       680       690       700  
pF1KB8 KLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQI
       :. ::. .::: .  : ..::::::::::::......:. . : :.::::   :..: ..
XP_006 KMLVLDYILAVTRS-RSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKV
        320       330        340       350       360       370     

            710       720       730       740       750       760  
pF1KB8 VDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYP
       :. :::  :  :.:.::::::: ::::::...:...: :::::.: :::.::::::::  
XP_006 VERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKT
         380       390       400       410       420       430     

            770       780       790       800       810       820  
pF1KB8 VHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCV
        .:::::..:::::::.:::  :..: . :::  .  :. .::. :::.:: : :.:   
XP_006 CYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVER-HFSLGELKELFILDEASLSD
         440       450       460       470        480       490    

            830       840       850       860       870       880  
pF1KB8 THDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHL
       ::: : :.             . . ::  :. :  . :.       :.:  :.: . :. 
XP_006 THDRLHCR-------------RCVNSR--QIRPPPDGSDCT-----SDLAGWNHCT-DKW
          500                      510       520            530    

            890           900       910  
pF1KB8 NLTDPFLERI----TENVSFIFQNITTQATGT  
       .: :  :.      .  ..:.:.           
XP_006 GLRDEVLQAAWDAASTAITFVFHQRSHEEQRGLR
           540       550       560       

>>NP_001192191 (OMIM: 604289,605027) DNA repair and reco  (117 aa)
 initn: 697 init1: 697 opt: 697  Z-score: 849.4  bits: 165.5 E(85289): 1.4e-40
Smith-Waterman score: 697; 98.1% identity (100.0% similar) in 104 aa overlap (1-104:1-104)

               10        20        30        40        50        60
pF1KB8 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSD
       ::::::::::::::::::::::::::::::::::::::::::..                
NP_001 RICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVQTWMRRHRLVPVHYR   
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB8 SLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEE

>>XP_011540601 (OMIM: 114480,603615,605027) PREDICTED: D  (489 aa)
 initn: 1231 init1: 554 opt: 699  Z-score: 842.9  bits: 166.3 E(85289): 3.3e-40
Smith-Waterman score: 1245; 43.8% identity (68.3% similar) in 502 aa overlap (405-901:12-478)

          380       390       400       410       420       430    
pF1KB8 QKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGH
                                     .:::::: .   .  ... .  :.::::::
XP_011                    MNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGH
                                  10        20        30        40 

          440       450       460       470       480       490    
pF1KB8 RLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEE
       :::::  .:  :: ::.  .:....:::::::: :.:.:. ::: ::::.   ..: .: 
XP_011 RLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFEL
              50        60        70        80        90       100 

          500       510       520       530       540       550    
pF1KB8 PIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGAL
       ::. .:. .::: ...:::.:  ::: ...  ..:::..:..:::: :::.:: ::   :
XP_011 PILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPL
             110       120       130       140       150       160 

          560        570       580       590       600       610   
pF1KB8 QIELYRKLL-NSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDK
       : :::...: ... ..  :.: .  :  :  : .:::::::: :...     .:      
XP_011 QTELYKRFLRQAKPAEELLEGKMSVSS-LSSITSLKKLCNHPALIYD-----KCV-----
             170       180        190       200            210     

           620       630       640       650       660       670   
pF1KB8 NEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTL
        ::.. . : :..::  :.   .  . :::. ::. .::: .  : ..::::::::::::
XP_011 -EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRS-RSSDKVVLVSNYTQTL
               220       230       240       250        260        

           680       690       700       710       720       730   
pF1KB8 NILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGS
       ......:. . : :.::::   :..: ..:. :::  :  :.:.::::::: ::::::..
XP_011 DLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGAN
      270       280       290       300       310       320        

           740       750       760       770       780       790   
pF1KB8 HLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVV
       .:...: :::::.: :::.::::::::   .:::::..:::::::.:::  :..: . ::
XP_011 RLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVV
      330       340       350       360       370       380        

           800       810       820       830       840       850   
pF1KB8 DLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQL
       :  .  :. .::. :::.:: : :.:   ::: : :.             . . ::  :.
XP_011 DEEQDVER-HFSLGELKELFILDEASLSDTHDRLHCR-------------RCVNSR--QI
      390        400       410       420                    430    

           860       870       880       890           900         
pF1KB8 GPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERI----TENVSFIFQNITTQATG
        :  . :.       :.:  :.: . :. .: :  :.      .  ..:.:.        
XP_011 RPPPDGSDCT-----SDLAGWNHCT-DKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQR
            440            450        460       470       480      

     910  
pF1KB8 T  
          
XP_011 GLR
          

>>XP_011540602 (OMIM: 114480,603615,605027) PREDICTED: D  (489 aa)
 initn: 1231 init1: 554 opt: 699  Z-score: 842.9  bits: 166.3 E(85289): 3.3e-40
Smith-Waterman score: 1245; 43.8% identity (68.3% similar) in 502 aa overlap (405-901:12-478)

          380       390       400       410       420       430    
pF1KB8 QKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGH
                                     .:::::: .   .  ... .  :.::::::
XP_011                    MNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGH
                                  10        20        30        40 

          440       450       460       470       480       490    
pF1KB8 RLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEE
       :::::  .:  :: ::.  .:....:::::::: :.:.:. ::: ::::.   ..: .: 
XP_011 RLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFEL
              50        60        70        80        90       100 

          500       510       520       530       540       550    
pF1KB8 PIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGAL
       ::. .:. .::: ...:::.:  ::: ...  ..:::..:..:::: :::.:: ::   :
XP_011 PILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPL
             110       120       130       140       150       160 

          560        570       580       590       600       610   
pF1KB8 QIELYRKLL-NSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDK
       : :::...: ... ..  :.: .  :  :  : .:::::::: :...     .:      
XP_011 QTELYKRFLRQAKPAEELLEGKMSVSS-LSSITSLKKLCNHPALIYD-----KCV-----
             170       180        190       200            210     

           620       630       640       650       660       670   
pF1KB8 NEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTL
        ::.. . : :..::  :.   .  . :::. ::. .::: .  : ..::::::::::::
XP_011 -EEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRS-RSSDKVVLVSNYTQTL
               220       230       240       250        260        

           680       690       700       710       720       730   
pF1KB8 NILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGS
       ......:. . : :.::::   :..: ..:. :::  :  :.:.::::::: ::::::..
XP_011 DLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGAN
      270       280       290       300       310       320        

           740       750       760       770       780       790   
pF1KB8 HLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVV
       .:...: :::::.: :::.::::::::   .:::::..:::::::.:::  :..: . ::
XP_011 RLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVV
      330       340       350       360       370       380        

           800       810       820       830       840       850   
pF1KB8 DLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQL
       :  .  :. .::. :::.:: : :.:   ::: : :.             . . ::  :.
XP_011 DEEQDVER-HFSLGELKELFILDEASLSDTHDRLHCR-------------RCVNSR--QI
      390        400       410       420                    430    

           860       870       880       890           900         
pF1KB8 GPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERI----TENVSFIFQNITTQATG
        :  . :.       :.:  :.: . :. .: :  :.      .  ..:.:.        
XP_011 RPPPDGSDCT-----SDLAGWNHCT-DKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQR
            440            450        460       470       480      

     910  
pF1KB8 T  
          
XP_011 GLR
          

>>NP_000115 (OMIM: 133540,211980,214150,278800,600630,60  (1493 aa)
 initn: 755 init1: 316 opt: 485  Z-score: 576.6  bits: 118.6 E(85289): 2.2e-25
Smith-Waterman score: 944; 34.6% identity (62.1% similar) in 541 aa overlap (288-815:499-1007)

       260       270       280       290       300         310     
pF1KB8 YTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYE--CVMGMR
                                     .  .:  .:  .:. :. .:.:  :     
NP_000 NKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHC-----
      470       480       490       500       510       520        

         320       330       340            350       360       370
pF1KB8 MNGRCGAILADEMGLGKTLQCISLIWTL-----QCQGPYGGKPVIKKTLIVTPGSLVNNW
          . :.::.::::::::.: :...  :     . .:       .  :.:: : .....:
NP_000 --QQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQW
             530       540       550       560       570       580 

              380         390       400         410       420      
pF1KB8 KKEFQKWLGSERIKIF--TVDQDHKVEEFIKSI--FYSVLIISYEMLLRSLDQIKNIKFD
        :::. :    :. :.  : .  :: :..:...   ...:: :: ..    :.:.   . 
NP_000 VKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWH
             590       600       610       620       630       640 

        430       440       450       460       470       480      
pF1KB8 LLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLS
        .: ::::...:    .: :  ..   .::::.:.:.::.:.:...:.::. :: ::.: 
NP_000 YVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLP
             650       660       670       680       690       700 

        490       500       510       520       530         540    
pF1KB8 SYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYL--PPKIE
        . . .  :: ..   .::  . . . . :  :    . ..::: .  ..  :  : : :
NP_000 VFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNE
             710       720       730       740       750       760 

          550       560       570       580       590       600    
pF1KB8 NVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKE
       .:.:::    : ..:.....:. :   :.: ..    ::   ::.:.:::: :.  :   
NP_000 QVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLI---ALRKICNHPDLF--SGGP
             770       780       790       800          810        

          610       620       630       640       650       660    
pF1KB8 KECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVV
       :. ..  : . :.. . :                :.:::. :. .:: . :  .  ..:.
NP_000 KNLKGLPDDELEEDQF-GYW--------------KRSGKMIVVESLLKIWH--KQGQRVL
        820       830                      840       850           

          670       680       690       700       710       720    
pF1KB8 LVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGG
       : :.  : :.::.   . . :.: ..:: : :..:: ..  .: . .:.:.:::....::
NP_000 LFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYN-EDTSIFVFLLTTRVGG
     860       870       880       890       900        910        

          730       740       750       760       770       780    
pF1KB8 VGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQIS
       .:.:: :......:: ::::.:: ::  :.:: :::  : .:::::.::::::::.::: 
NP_000 LGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIF
      920       930       940       950       960       970        

          790       800       810       820       830       840    
pF1KB8 KQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEK
       :: : . :.   :  .   :. ..: .::::                             
NP_000 KQFLTNRVLKDPKQRRF--FKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHL
      980       990        1000      1010      1020      1030      

          850       860       870       880       890       900    
pF1KB8 FIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNIT
                                                                   
NP_000 KRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPH
       1040      1050      1060      1070      1080      1090      

>>NP_001333369 (OMIM: 133540,211980,214150,278800,600630  (1493 aa)
 initn: 755 init1: 316 opt: 485  Z-score: 576.6  bits: 118.6 E(85289): 2.2e-25
Smith-Waterman score: 944; 34.6% identity (62.1% similar) in 541 aa overlap (288-815:499-1007)

       260       270       280       290       300         310     
pF1KB8 YTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYE--CVMGMR
                                     .  .:  .:  .:. :. .:.:  :     
NP_001 NKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHC-----
      470       480       490       500       510       520        

         320       330       340            350       360       370
pF1KB8 MNGRCGAILADEMGLGKTLQCISLIWTL-----QCQGPYGGKPVIKKTLIVTPGSLVNNW
          . :.::.::::::::.: :...  :     . .:       .  :.:: : .....:
NP_001 --QQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQW
             530       540       550       560       570       580 

              380         390       400         410       420      
pF1KB8 KKEFQKWLGSERIKIF--TVDQDHKVEEFIKSI--FYSVLIISYEMLLRSLDQIKNIKFD
        :::. :    :. :.  : .  :: :..:...   ...:: :: ..    :.:.   . 
NP_001 VKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWH
             590       600       610       620       630       640 

        430       440       450       460       470       480      
pF1KB8 LLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLS
        .: ::::...:    .: :  ..   .::::.:.:.::.:.:...:.::. :: ::.: 
NP_001 YVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLP
             650       660       670       680       690       700 

        490       500       510       520       530         540    
pF1KB8 SYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYL--PPKIE
        . . .  :: ..   .::  . . . . :  :    . ..::: .  ..  :  : : :
NP_001 VFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNE
             710       720       730       740       750       760 

          550       560       570       580       590       600    
pF1KB8 NVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKE
       .:.:::    : ..:.....:. :   :.: ..    ::   ::.:.:::: :.  :   
NP_001 QVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLI---ALRKICNHPDLF--SGGP
             770       780       790       800          810        

          610       620       630       640       650       660    
pF1KB8 KECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVV
       :. ..  : . :.. . :                :.:::. :. .:: . :  .  ..:.
NP_001 KNLKGLPDDELEEDQF-GYW--------------KRSGKMIVVESLLKIWH--KQGQRVL
        820       830                      840       850           

          670       680       690       700       710       720    
pF1KB8 LVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGG
       : :.  : :.::.   . . :.: ..:: : :..:: ..  .: . .:.:.:::....::
NP_001 LFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYN-EDTSIFVFLLTTRVGG
     860       870       880       890       900        910        

          730       740       750       760       770       780    
pF1KB8 VGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQIS
       .:.:: :......:: ::::.:: ::  :.:: :::  : .:::::.::::::::.::: 
NP_001 LGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIF
      920       930       940       950       960       970        

          790       800       810       820       830       840    
pF1KB8 KQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEK
       :: : . :.   :  .   :. ..: .::::                             
NP_001 KQFLTNRVLKDPKQRRF--FKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHL
      980       990        1000      1010      1020      1030      

          850       860       870       880       890       900    
pF1KB8 FIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNIT
                                                                   
NP_001 KRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPH
       1040      1050      1060      1070      1080      1090      




910 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:43:16 2016 done: Sat Nov  5 16:43:18 2016
 Total Scan time: 13.290 Total Display time:  0.180

Function used was FASTA [36.3.4 Apr, 2011]
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