Result of FASTA (omim) for pF1KB5840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5840, 482 aa
  1>>>pF1KB5840 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3365+/-0.000357; mu= 16.1760+/- 0.022
 mean_var=155.0157+/-32.569, 0's: 0 Z-trim(119.1): 27  B-trim: 222 in 2/50
 Lambda= 0.103012
 statistics sampled from 32697 (32735) to 32697 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.384), width:  16
 Scan time:  9.240

The best scores are:                                      opt bits E(85289)
NP_038474 (OMIM: 607754) E3 ubiquitin-protein liga ( 482) 3331 506.9 5.2e-143
XP_011514300 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 418) 2909 444.1 3.6e-124
XP_011514299 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 418) 2909 444.1 3.6e-124
XP_011514298 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 439) 2610 399.7 8.9e-111
NP_001138597 (OMIM: 607754) E3 ubiquitin-protein l ( 329) 2255 346.8 5.6e-95
NP_001278592 (OMIM: 607754) E3 ubiquitin-protein l ( 265) 1833 283.9 3.7e-76
NP_005655 (OMIM: 176270,603856,615346) probable E3 ( 507) 1440 225.8 2.1e-58
NP_001258636 (OMIM: 608426) probable E3 ubiquitin- ( 373) 1038 166.0 1.7e-40
NP_054879 (OMIM: 608426) probable E3 ubiquitin-pro ( 416) 1038 166.0 1.8e-40


>>NP_038474 (OMIM: 607754) E3 ubiquitin-protein ligase m  (482 aa)
 initn: 3331 init1: 3331 opt: 3331  Z-score: 2688.4  bits: 506.9 E(85289): 5.2e-143
Smith-Waterman score: 3331; 99.8% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB5 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 LQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 YKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 YKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 ELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_038 ELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDL
              430       440       450       460       470       480

         
pF1KB5 DL
       ::
NP_038 DL
         

>>XP_011514300 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr  (418 aa)
 initn: 2909 init1: 2909 opt: 2909  Z-score: 2350.2  bits: 444.1 E(85289): 3.6e-124
Smith-Waterman score: 2909; 99.8% identity (100.0% similar) in 418 aa overlap (65-482:1-418)

           40        50        60        70        80        90    
pF1KB5 TAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                             10        20        30

          100       110       120       130       140       150    
pF1KB5 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
               40        50        60        70        80        90

          160       170       180       190       200       210    
pF1KB5 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
              100       110       120       130       140       150

          220       230       240       250       260       270    
pF1KB5 PYAAVGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 PYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
              160       170       180       190       200       210

          280       290       300       310       320       330    
pF1KB5 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
              220       230       240       250       260       270

          340       350       360       370       380       390    
pF1KB5 RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPD
              280       290       300       310       320       330

          400       410       420       430       440       450    
pF1KB5 GRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAA
              340       350       360       370       380       390

          460       470       480  
pF1KB5 GGDDELTDSEDEWDLFHDELEDFYDLDL
       ::::::::::::::::::::::::::::
XP_011 GGDDELTDSEDEWDLFHDELEDFYDLDL
              400       410        

>>XP_011514299 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr  (418 aa)
 initn: 2909 init1: 2909 opt: 2909  Z-score: 2350.2  bits: 444.1 E(85289): 3.6e-124
Smith-Waterman score: 2909; 99.8% identity (100.0% similar) in 418 aa overlap (65-482:1-418)

           40        50        60        70        80        90    
pF1KB5 TAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                             10        20        30

          100       110       120       130       140       150    
pF1KB5 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
               40        50        60        70        80        90

          160       170       180       190       200       210    
pF1KB5 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
              100       110       120       130       140       150

          220       230       240       250       260       270    
pF1KB5 PYAAVGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_011 PYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
              160       170       180       190       200       210

          280       290       300       310       320       330    
pF1KB5 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
              220       230       240       250       260       270

          340       350       360       370       380       390    
pF1KB5 RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPD
              280       290       300       310       320       330

          400       410       420       430       440       450    
pF1KB5 GRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLLAA
              340       350       360       370       380       390

          460       470       480  
pF1KB5 GGDDELTDSEDEWDLFHDELEDFYDLDL
       ::::::::::::::::::::::::::::
XP_011 GGDDELTDSEDEWDLFHDELEDFYDLDL
              400       410        

>>XP_011514298 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr  (439 aa)
 initn: 2610 init1: 2610 opt: 2610  Z-score: 2109.8  bits: 399.7 E(85289): 8.9e-111
Smith-Waterman score: 2900; 90.9% identity (91.1% similar) in 482 aa overlap (1-482:1-439)

               10        20        30        40        50        60
pF1KB5 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
       :::                                           ::::::::::::::
XP_011 CRY-------------------------------------------EHSKPLKQEEATAT
                                                          70       

              130       140       150       160       170       180
pF1KB5 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
        80        90       100       110       120       130       

              190       200       210       220       230       240
pF1KB5 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
       140       150       160       170       180       190       

              250       260       270       280       290       300
pF1KB5 LQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
       200       210       220       230       240       250       

              310       320       330       340       350       360
pF1KB5 ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
       260       270       280       290       300       310       

              370       380       390       400       410       420
pF1KB5 YKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFW
       320       330       340       350       360       370       

              430       440       450       460       470       480
pF1KB5 ELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDL
       380       390       400       410       420       430       

         
pF1KB5 DL
       ::
XP_011 DL
         

>>NP_001138597 (OMIM: 607754) E3 ubiquitin-protein ligas  (329 aa)
 initn: 2255 init1: 2255 opt: 2255  Z-score: 1826.1  bits: 346.8 E(85289): 5.6e-95
Smith-Waterman score: 2255; 99.7% identity (100.0% similar) in 329 aa overlap (1-329:1-329)

               10        20        30        40        50        60
pF1KB5 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATAT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVGAGSEDWVNAIEFVPGQPYCG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 ILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILK
       :::::::::::::::::::::::::::::                               
NP_001 ILSNCNHTYCLKCIRKWRSAKQFESKIIK                               
              310       320                                        

>>NP_001278592 (OMIM: 607754) E3 ubiquitin-protein ligas  (265 aa)
 initn: 1833 init1: 1833 opt: 1833  Z-score: 1488.3  bits: 283.9 E(85289): 3.7e-76
Smith-Waterman score: 1833; 99.6% identity (100.0% similar) in 265 aa overlap (65-329:1-265)

           40        50        60        70        80        90    
pF1KB5 TAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
                                             10        20        30

          100       110       120       130       140       150    
pF1KB5 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNS
               40        50        60        70        80        90

          160       170       180       190       200       210    
pF1KB5 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLC
              100       110       120       130       140       150

          220       230       240       250       260       270    
pF1KB5 PYAAVGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
       ::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_001 PYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQ
              160       170       180       190       200       210

          280       290       300       310       320       330    
pF1KB5 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::     
NP_001 RSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIK     
              220       230       240       250       260          

          340       350       360       370       380       390    
pF1KB5 RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAYPD

>>NP_005655 (OMIM: 176270,603856,615346) probable E3 ubi  (507 aa)
 initn: 1419 init1: 1125 opt: 1440  Z-score: 1169.4  bits: 225.8 E(85289): 2.1e-58
Smith-Waterman score: 1618; 51.5% identity (70.9% similar) in 505 aa overlap (2-482:20-507)

                                 10              20           30   
pF1KB5                   MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
                          ::::  :...        :: .::  .:   :: . .:.:.
NP_005 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
               10        20        30        40        50        60

             40                    50        60        70        80
pF1KB5 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHD
       . .:. :  ::      .:::.      . :.: ::::. :::..:: ::::.:::::::
NP_005 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
               70        80        90       100       110       120

               90       100       110       120       130          
pF1KB5 LSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVG
       ::   ...       :    :      : .:  :: : :          :.::::  ..:
NP_005 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIG
              130       140       150       160               170  

     140       150        160       170       180       190        
pF1KB5 PLVEMNTGEAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKE
         .: .  :::  :..  :. ::: :.:..:::::::::: :: . :  :::::.:    
NP_005 SAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----
            180       190       200       210       220            

      200       210       220       230       240       250        
pF1KB5 ESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQHIKS
       :.:..: :: .  ..: ::. : :  ::.:.::::: ::::::: ::::::::: .:...
NP_005 ETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRA
      230       240       250       260       270       280        

      260       270       280       290       300       310        
pF1KB5 CIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWR
       :::::::::::::::::. : :::::::::::::::..:::::::::::..:..:::.::
NP_005 CIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWR
      290       300       310       320       330       340        

      320       330       340       350       360       370        
pF1KB5 SAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRG
       ::.:::..:.::::.::.::..:::::.::::.::::::: .::::::::::::: ::::
NP_005 SARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRG
      350       360       370       380       390       400        

      380       390       400       410       420       430        
pF1KB5 SCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEE
       .:::: .::::: ::.:  .::     :. : :  :    . : ..  :..  . . ..:
NP_005 NCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKE
      410       420       430       440           450       460    

      440       450       460       470       480  
pF1KB5 VVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
       .:...:. .:.  . .   :::  :::.:::.: :::....: :
NP_005 LVVLRLASLLFKRFLSL-RDELPFSEDQWDLLHYELEEYFNLIL
          470       480        490       500       

>>NP_001258636 (OMIM: 608426) probable E3 ubiquitin-prot  (373 aa)
 initn: 1016 init1: 975 opt: 1038  Z-score: 848.0  bits: 166.0 E(85289): 1.7e-40
Smith-Waterman score: 1060; 44.2% identity (71.1% similar) in 360 aa overlap (104-451:8-365)

            80        90       100       110        120       130  
pF1KB5 NCRYSHDLSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEE-ATATELTTKSSLAASS
                                     :::.:..:      :..:   .  : :  :
NP_001                        MSTKQITCRYDHTRPSAAAGGAVGTMAHSVPSPAFHS
                                      10        20        30       

              140       150       160           170       180      
pF1KB5 SL--SSIVGPLVEMNTGEAESRNSNFATVG----AGSEDWVNAIEFVPGQPYCGRTAPSC
           : ... .:. :. :  .:..   ..     .:  .  .   .: .   :.   :: 
NP_001 PHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSP
        40        50        60        70        80        90       

        190          200       210       220       230       240   
pF1KB5 TEAP---LQGSVTKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQL
          :   :..  .  .. . ...  ...:::::::.::::.:. ::::::. :..: ::.
NP_001 EMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQV
       100       110       120       130       140       150       

           250       260       270       280       290       300   
pF1KB5 LHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILS
       :::.:  ::. : : :. . :..:: .:: : :.: ::.:::::. :::. :::::::::
NP_001 LHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILS
       160       170       180       190       200       210       

           310       320       330       340       350       360   
pF1KB5 NCNHTYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKE
       ::::::::.:::.:: :::::. :::::::::. :.::::: ::::....:..::  .:.
NP_001 NCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQ
       220       230       240       250       260       270       

           370       380       390       400       410         420 
pF1KB5 AMSNKACRYFDEGRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRN--HFWE
       .:..:::.::..:.:.::::..:.:.:::::::  ::.. .   ::.  ..  :  ..:.
NP_001 GMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWD
       280       290       300       310       320       330       

             430       440       450       460       470       480 
pF1KB5 LIEERENSNPFDNDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLD
       .::.::. .  .:  :.:   :::.... :                              
NP_001 FIENRESRHVPNN--EDVDMTELGDLFMHLSGVESSEP                      
       340       350         360       370                         

>>NP_054879 (OMIM: 608426) probable E3 ubiquitin-protein  (416 aa)
 initn: 1285 init1: 975 opt: 1038  Z-score: 847.5  bits: 166.0 E(85289): 1.8e-40
Smith-Waterman score: 1329; 46.8% identity (73.3% similar) in 408 aa overlap (56-451:3-408)

          30        40        50        60        70        80     
pF1KB5 ASPTPIPTVTAPSLGAGGGGGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSP
                                     :::.::::::::::.::..: .::::..: 
NP_054                             MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
                                           10        20        30  

          90       100       110        120       130         140  
pF1KB5 YSVVCKYFQRGYCIYGDRCRYEHSKPLKQEE-ATATELTTKSSLAASSSL--SSIVGPLV
        :..:::.:.::: :: ::::.:..:      :..:   .  : :  :    : ... .:
NP_054 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIV
             40        50        60        70        80        90  

            150       160           170       180       190        
pF1KB5 EMNTGEAESRNSNFATVG----AGSEDWVNAIEFVPGQPYCGRTAPSCTEAP---LQGSV
       . :. :  .:..   ..     .:  .  .   .: .   :.   ::    :   :..  
NP_054 KTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIR
            100       110       120       130       140       150  

         200       210       220       230       240       250     
pF1KB5 TKEESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQH
       .  .. . ...  ...:::::::.::::.:. ::::::. :..: ::.:::.:  ::. :
NP_054 SGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAH
            160       170       180       190       200       210  

         260       270       280       290       300       310     
pF1KB5 IKSCIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIR
        : :. . :..:: .:: : :.: ::.:::::. :::. :::::::::::::::::.:::
NP_054 EKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIR
            220       230       240       250       260       270  

         320       330       340       350       360       370     
pF1KB5 KWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDE
       .:: :::::. :::::::::. :.::::: ::::....:..::  .:..:..:::.::..
NP_054 QWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQ
            280       290       300       310       320       330  

         380       390       400       410         420       430   
pF1KB5 GRGSCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRN--HFWELIEERENSNPFD
       :.:.::::..:.:.:::::::  ::.. .   ::.  ..  :  ..:..::.::. .  .
NP_054 GKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPN
            340       350       360       370       380       390  

           440       450       460       470       480  
pF1KB5 NDEEEVVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
       :  :.:   :::.... :                               
NP_054 N--EDVDMTELGDLFMHLSGVESSEP                       
              400       410                             




482 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:08:20 2016 done: Sat Nov  5 15:08:22 2016
 Total Scan time:  9.240 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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