Result of FASTA (omim) for pF1KB9973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9973, 554 aa
  1>>>pF1KB9973 554 - 554 aa - 554 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.6534+/-0.000411; mu= -21.7123+/- 0.025
 mean_var=423.2969+/-87.746, 0's: 0 Z-trim(122.4): 8  B-trim: 0 in 0/58
 Lambda= 0.062338
 statistics sampled from 40466 (40474) to 40466 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.475), width:  16
 Scan time: 10.380

The best scores are:                                      opt bits E(85289)
NP_757351 (OMIM: 120420) macrophage colony-stimula ( 554) 3783 354.6 4.9e-97
NP_000748 (OMIM: 120420) macrophage colony-stimula ( 554) 3783 354.6 4.9e-97
XP_016855858 (OMIM: 120420) PREDICTED: macrophage  ( 513) 3495 328.6 2.9e-89
NP_757349 (OMIM: 120420) macrophage colony-stimula ( 438) 2493 238.5 3.3e-62
NP_757350 (OMIM: 120420) macrophage colony-stimula ( 256) 1215 123.4 8.4e-28


>>NP_757351 (OMIM: 120420) macrophage colony-stimulating  (554 aa)
 initn: 3783 init1: 3783 opt: 3783  Z-score: 1863.2  bits: 354.6 E(85289): 4.9e-97
Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)

               10        20        30        40        50        60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
              490       500       510       520       530       540

              550    
pF1KB9 SPLTQDDRQVELPV
       ::::::::::::::
NP_757 SPLTQDDRQVELPV
              550    

>>NP_000748 (OMIM: 120420) macrophage colony-stimulating  (554 aa)
 initn: 3783 init1: 3783 opt: 3783  Z-score: 1863.2  bits: 354.6 E(85289): 4.9e-97
Smith-Waterman score: 3783; 100.0% identity (100.0% similar) in 554 aa overlap (1-554:1-554)

               10        20        30        40        50        60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
              490       500       510       520       530       540

              550    
pF1KB9 SPLTQDDRQVELPV
       ::::::::::::::
NP_000 SPLTQDDRQVELPV
              550    

>>XP_016855858 (OMIM: 120420) PREDICTED: macrophage colo  (513 aa)
 initn: 3495 init1: 3495 opt: 3495  Z-score: 1723.7  bits: 328.6 E(85289): 2.9e-89
Smith-Waterman score: 3495; 99.8% identity (99.8% similar) in 513 aa overlap (42-554:1-513)

              20        30        40        50        60        70 
pF1KB9 PTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVD
                                     ::::::::::::::::::::::::::::::
XP_016                               MIGSGHLQSLQRLIDSQMETSCQITFEFVD
                                             10        20        30

              80        90       100       110       120       130 
pF1KB9 QEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHD
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KB9 KACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNC
              100       110       120       130       140       150

             200       210       220       230       240       250 
pF1KB9 LYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQ
              160       170       180       190       200       210

             260       270       280       290       300       310 
pF1KB9 RPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGE
              220       230       240       250       260       270

             320       330       340       350       360       370 
pF1KB9 ASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVG
              280       290       300       310       320       330

             380       390       400       410       420       430 
pF1KB9 PVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSS
              340       350       360       370       380       390

             440       450       460       470       480       490 
pF1KB9 GSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 GSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSFSP
              400       410       420       430       440       450

             500       510       520       530       540       550 
pF1KB9 QLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVE
              460       470       480       490       500       510

          
pF1KB9 LPV
       :::
XP_016 LPV
          

>>NP_757349 (OMIM: 120420) macrophage colony-stimulating  (438 aa)
 initn: 2493 init1: 2493 opt: 2493  Z-score: 1237.7  bits: 238.5 E(85289): 3.3e-62
Smith-Waterman score: 2741; 79.1% identity (79.1% similar) in 554 aa overlap (1-554:1-438)

               10        20        30        40        50        60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 LHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 DVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLS
       ::::                                                        
NP_757 DVTG--------------------------------------------------------
                                                                   

              430       440       450       460       470       480
pF1KB9 AQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTG
                                                                   
NP_757 ------------------------------------------------------------
                                                                   

              490       500       510       520       530       540
pF1KB9 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 HERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEG
          370       380       390       400       410       420    

              550    
pF1KB9 SPLTQDDRQVELPV
       ::::::::::::::
NP_757 SPLTQDDRQVELPV
          430        

>>NP_757350 (OMIM: 120420) macrophage colony-stimulating  (256 aa)
 initn: 1243 init1: 1215 opt: 1215  Z-score: 620.1  bits: 123.4 E(85289): 8.4e-28
Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)

               10        20        30        40        50        60
pF1KB9 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQME
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 TSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_757 SCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 QDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQP
       :                                                           
NP_757 QGHERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQP
              190       200       210       220       230       240

>--
 initn: 505 init1: 505 opt: 505  Z-score: 275.0  bits: 59.6 E(85289): 1.4e-08
Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 75 aa overlap (480-554:182-256)

     450       460       470       480       490       500         
pF1KB9 RSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSSSPQLQESVFHLLVPSVILVL
                                     ::::::::::::::::::::::::::::::
NP_757 VFNETKNLLDKDWNIFSKNCNNSFAECSSQGHERQSEGSSSPQLQESVFHLLVPSVILVL
             160       170       180       190       200       210 

     510       520       530       540       550    
pF1KB9 LAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV
       :::::::::::::::::::::::::::::::::::::::::::::
NP_757 LAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV
             220       230       240       250      




554 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 15:01:16 2016 done: Sat Nov  5 15:01:17 2016
 Total Scan time: 10.380 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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