Result of FASTA (omim) for pF1KB9914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9914, 533 aa
  1>>>pF1KB9914 533 - 533 aa - 533 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2993+/-0.000434; mu= 19.4017+/- 0.027
 mean_var=82.2298+/-16.401, 0's: 0 Z-trim(111.3): 210  B-trim: 555 in 1/54
 Lambda= 0.141436
 statistics sampled from 19596 (19815) to 19596 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.232), width:  16
 Scan time:  9.440

The best scores are:                                      opt bits E(85289)
NP_001001567 (OMIM: 602973) high affinity cGMP-spe ( 533) 3589 742.6 6.7e-214
NP_001001570 (OMIM: 602973) high affinity cGMP-spe ( 540) 3355 694.9 1.6e-199
NP_001001571 (OMIM: 602973) high affinity cGMP-spe ( 492) 3279 679.4  7e-195
NP_001001574 (OMIM: 602973) high affinity cGMP-spe ( 507) 3119 646.7 4.8e-185
NP_001001568 (OMIM: 602973) high affinity cGMP-spe ( 466) 3112 645.3 1.2e-184
NP_001302462 (OMIM: 602973) high affinity cGMP-spe ( 485) 3112 645.3 1.3e-184
NP_001001581 (OMIM: 602973) high affinity cGMP-spe ( 526) 3024 627.3 3.4e-179
XP_011527900 (OMIM: 602973) PREDICTED: high affini ( 545) 3024 627.4 3.5e-179
NP_001001582 (OMIM: 602973) high affinity cGMP-spe ( 552) 3024 627.4 3.5e-179
NP_001001583 (OMIM: 602973) high affinity cGMP-spe ( 567) 3024 627.4 3.6e-179
NP_002597 (OMIM: 602973) high affinity cGMP-specif ( 593) 3024 627.4 3.7e-179
NP_001001578 (OMIM: 602973) high affinity cGMP-spe ( 491) 2929 607.9 2.2e-173
NP_001001575 (OMIM: 602973) high affinity cGMP-spe ( 433) 2926 607.3 3.1e-173
NP_001001577 (OMIM: 602973) high affinity cGMP-spe ( 459) 2924 606.9 4.2e-173
NP_001001569 (OMIM: 602973) high affinity cGMP-spe ( 465) 2918 605.7  1e-172
NP_001001572 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6  4e-157
NP_001001579 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6  4e-157
NP_001001573 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6  4e-157
NP_001001584 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6  4e-157
XP_016883855 (OMIM: 602973) PREDICTED: high affini ( 386) 2663 553.6  4e-157
NP_001001585 (OMIM: 602973) high affinity cGMP-spe ( 386) 2663 553.6  4e-157
NP_001001580 (OMIM: 602973) high affinity cGMP-spe ( 376) 2598 540.3 3.9e-153
NP_001001576 (OMIM: 602973) high affinity cGMP-spe ( 376) 2598 540.3 3.9e-153
XP_011527902 (OMIM: 602973) PREDICTED: high affini ( 502) 2087 436.1 1.2e-121
XP_016883856 (OMIM: 602973) PREDICTED: high affini ( 328)  807 174.8 3.6e-43
XP_005259990 (OMIM: 600126) PREDICTED: cAMP-specif ( 582)  606 134.0 1.2e-30
NP_001284371 (OMIM: 600127) cAMP-specific 3',5'-cy ( 503)  605 133.7 1.3e-30
XP_005270981 (OMIM: 600127) PREDICTED: cAMP-specif ( 517)  605 133.7 1.3e-30
XP_005270982 (OMIM: 600127) PREDICTED: cAMP-specif ( 517)  605 133.7 1.3e-30
XP_016856935 (OMIM: 600127) PREDICTED: cAMP-specif ( 530)  605 133.8 1.3e-30
XP_011539868 (OMIM: 600127) PREDICTED: cAMP-specif ( 530)  605 133.8 1.3e-30
XP_006710743 (OMIM: 600127) PREDICTED: cAMP-specif ( 531)  605 133.8 1.3e-30
NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cycli ( 647)  606 134.0 1.3e-30
NP_001032416 (OMIM: 600127) cAMP-specific 3',5'-cy ( 564)  605 133.8 1.4e-30
XP_016856934 (OMIM: 600127) PREDICTED: cAMP-specif ( 597)  605 133.8 1.4e-30
NP_001284369 (OMIM: 600127) cAMP-specific 3',5'-cy ( 644)  605 133.8 1.5e-30
NP_001284370 (OMIM: 600127) cAMP-specific 3',5'-cy ( 661)  605 133.8 1.5e-30
NP_001104779 (OMIM: 600126) cAMP-specific 3',5'-cy ( 825)  606 134.1 1.6e-30
NP_001104778 (OMIM: 600126) cAMP-specific 3',5'-cy ( 860)  606 134.1 1.6e-30
NP_001230050 (OMIM: 600126) cAMP-specific 3',5'-cy ( 864)  606 134.1 1.6e-30
XP_011526356 (OMIM: 600126) PREDICTED: cAMP-specif ( 864)  606 134.1 1.6e-30
NP_001032417 (OMIM: 600127) cAMP-specific 3',5'-cy ( 721)  605 133.9 1.7e-30
XP_016882354 (OMIM: 600126) PREDICTED: cAMP-specif ( 885)  606 134.1 1.7e-30
NP_001104777 (OMIM: 600126) cAMP-specific 3',5'-cy ( 886)  606 134.1 1.7e-30
NP_002591 (OMIM: 600127) cAMP-specific 3',5'-cycli ( 736)  605 133.9 1.7e-30
NP_001032418 (OMIM: 600127) cAMP-specific 3',5'-cy ( 736)  605 133.9 1.7e-30
NP_001184150 (OMIM: 600129,606799,614613) cAMP-spe ( 507)  593 131.3 6.9e-30
NP_001184152 (OMIM: 600129,606799,614613) cAMP-spe ( 518)  593 131.3   7e-30
XP_016865060 (OMIM: 600129,606799,614613) PREDICTE ( 553)  593 131.3 7.4e-30
XP_016865059 (OMIM: 600129,606799,614613) PREDICTE ( 553)  593 131.3 7.4e-30


>>NP_001001567 (OMIM: 602973) high affinity cGMP-specifi  (533 aa)
 initn: 3589 init1: 3589 opt: 3589  Z-score: 3961.1  bits: 742.6 E(85289): 6.7e-214
Smith-Waterman score: 3589; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533)

               10        20        30        40        50        60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
              430       440       450       460       470       480

              490       500       510       520       530   
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
              490       500       510       520       530   

>>NP_001001570 (OMIM: 602973) high affinity cGMP-specifi  (540 aa)
 initn: 3381 init1: 2918 opt: 3355  Z-score: 3703.0  bits: 694.9 E(85289): 1.6e-199
Smith-Waterman score: 3355; 93.5% identity (96.3% similar) in 541 aa overlap (1-533:1-540)

               10        20        30        40        50        60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
               10        20        30        40        50        60

               70        80           90          100         110  
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQL---SEREELI---QSVLAQV-AEQFS-RAFKINE
       :::::::::::::.   .  .....:     .:      .:: ... ..: . :::::::
NP_001 VSIDPTMPANSERNEL-ILYTSLRNLLFLPSKESWASHQHSVQSETCGHQATLRAFKINE
               70         80        90       100       110         

            120       130       140       150       160       170  
pF1KB9 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHK
     120       130       140       150       160       170         

            180       190       200       210       220       230  
pF1KB9 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINP
     180       190       200       210       220       230         

            240       250       260       270       280       290  
pF1KB9 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICH
     240       250       260       270       280       290         

            300       310       320       330       340       350  
pF1KB9 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQI
     300       310       320       330       340       350         

            360       370       380       390       400       410  
pF1KB9 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEV
     360       370       380       390       400       410         

            420       430       440       450       460       470  
pF1KB9 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLF
     420       430       440       450       460       470         

            480       490       500       510       520       530  
pF1KB9 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDC
     480       490       500       510       520       530         

        
pF1KB9 A
       :
NP_001 A
     540

>>NP_001001571 (OMIM: 602973) high affinity cGMP-specifi  (492 aa)
 initn: 3279 init1: 3279 opt: 3279  Z-score: 3619.7  bits: 679.4 E(85289): 7e-195
Smith-Waterman score: 3279; 100.0% identity (100.0% similar) in 487 aa overlap (47-533:6-492)

         20        30        40        50        60        70      
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
                                     ::::::::::::::::::::::::::::::
NP_001                          MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
                                        10        20        30     

         80        90       100       110       120       130      
pF1KB9 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
          40        50        60        70        80        90     

        140       150       160       170       180       190      
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
         100       110       120       130       140       150     

        200       210       220       230       240       250      
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
         160       170       180       190       200       210     

        260       270       280       290       300       310      
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
         220       230       240       250       260       270     

        320       330       340       350       360       370      
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
         280       290       300       310       320       330     

        380       390       400       410       420       430      
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
         340       350       360       370       380       390     

        440       450       460       470       480       490      
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
         400       410       420       430       440       450     

        500       510       520       530   
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::::::::::::
NP_001 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
         460       470       480       490  

>>NP_001001574 (OMIM: 602973) high affinity cGMP-specifi  (507 aa)
 initn: 3119 init1: 3119 opt: 3119  Z-score: 3443.1  bits: 646.7 E(85289): 4.8e-185
Smith-Waterman score: 3367; 95.1% identity (95.1% similar) in 533 aa overlap (1-533:1-507)

               10        20        30        40        50        60
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
       :::::::::::::::::::::::::::::::::::::::::::::::             
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR-------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB9 VSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
                    :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------TPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANH
                     50        60        70        80        90    

              130       140       150       160       170       180
pF1KB9 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB9 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB9 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB9 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB9 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB9 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
          400       410       420       430       440       450    

              490       500       510       520       530   
pF1KB9 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
          460       470       480       490       500       

>>NP_001001568 (OMIM: 602973) high affinity cGMP-specifi  (466 aa)
 initn: 3112 init1: 3112 opt: 3112  Z-score: 3435.9  bits: 645.3 E(85289): 1.2e-184
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 460 aa overlap (74-533:7-466)

            50        60        70        80        90       100   
pF1KB9 GLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
                                     ::::::::::::::::::::::::::::::
NP_001                         MDAFRSTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
                                       10        20        30      

           110       120       130       140       150       160   
pF1KB9 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
         40        50        60        70        80        90      

           170       180       190       200       210       220   
pF1KB9 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
        100       110       120       130       140       150      

           230       240       250       260       270       280   
pF1KB9 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
        160       170       180       190       200       210      

           290       300       310       320       330       340   
pF1KB9 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
        220       230       240       250       260       270      

           350       360       370       380       390       400   
pF1KB9 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
        280       290       300       310       320       330      

           410       420       430       440       450       460   
pF1KB9 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
        340       350       360       370       380       390      

           470       480       490       500       510       520   
pF1KB9 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
        400       410       420       430       440       450      

           530   
pF1KB9 DVKNSEGDCA
       ::::::::::
NP_001 DVKNSEGDCA
        460      

>>NP_001302462 (OMIM: 602973) high affinity cGMP-specifi  (485 aa)
 initn: 3112 init1: 3112 opt: 3112  Z-score: 3435.7  bits: 645.3 E(85289): 1.3e-184
Smith-Waterman score: 3112; 100.0% identity (100.0% similar) in 460 aa overlap (74-533:26-485)

            50        60        70        80        90       100   
pF1KB9 GLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
                                     ::::::::::::::::::::::::::::::
NP_001      MSSFSIHHSVTCCFYLVRSHGRPTSTPYKVRPVAIKQLSEREELIQSVLAQVAEQ
                    10        20        30        40        50     

           110       120       130       140       150       160   
pF1KB9 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPC
          60        70        80        90       100       110     

           170       180       190       200       210       220   
pF1KB9 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLG
         120       130       140       150       160       170     

           230       240       250       260       270       280   
pF1KB9 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDIL
         180       190       200       210       220       230     

           290       300       310       320       330       340   
pF1KB9 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSN
         240       250       260       270       280       290     

           350       360       370       380       390       400   
pF1KB9 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDI
         300       310       320       330       340       350     

           410       420       430       440       450       460   
pF1KB9 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP
         360       370       380       390       400       410     

           470       480       490       500       510       520   
pF1KB9 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSR
         420       430       440       450       460       470     

           530   
pF1KB9 DVKNSEGDCA
       ::::::::::
NP_001 DVKNSEGDCA
         480     

>>NP_001001581 (OMIM: 602973) high affinity cGMP-specifi  (526 aa)
 initn: 3098 init1: 3023 opt: 3024  Z-score: 3338.2  bits: 627.3 E(85289): 3.4e-179
Smith-Waterman score: 3024; 94.3% identity (96.0% similar) in 477 aa overlap (57-533:57-526)

         30        40        50        60        70        80      
pF1KB9 SKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQL
                                     ....:   :  : .  .   .. :      
NP_001 RTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPP------
         30        40        50        60        70        80      

         90       100       110       120       130       140      
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
                90       100       110       120       130         

        150       160       170       180       190       200      
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
     140       150       160       170       180       190         

        210       220       230       240       250       260      
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
     200       210       220       230       240       250         

        270       280       290       300       310       320      
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
     260       270       280       290       300       310         

        330       340       350       360       370       380      
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
     320       330       340       350       360       370         

        390       400       410       420       430       440      
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
     380       390       400       410       420       430         

        450       460       470       480       490       500      
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
     440       450       460       470       480       490         

        510       520       530   
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::
NP_001 TDSLTSGATEKSRERSRDVKNSEGDCA
     500       510       520      

>>XP_011527900 (OMIM: 602973) PREDICTED: high affinity c  (545 aa)
 initn: 3098 init1: 3023 opt: 3024  Z-score: 3337.9  bits: 627.4 E(85289): 3.5e-179
Smith-Waterman score: 3024; 94.3% identity (96.0% similar) in 477 aa overlap (57-533:76-545)

         30        40        50        60        70        80      
pF1KB9 SKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQL
                                     ....:   :  : .  .   .. :      
XP_011 RTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPP------
          50        60        70        80        90               

         90       100       110       120       130       140      
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
      100       110       120       130       140       150        

        150       160       170       180       190       200      
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
      160       170       180       190       200       210        

        210       220       230       240       250       260      
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
      220       230       240       250       260       270        

        270       280       290       300       310       320      
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
      280       290       300       310       320       330        

        330       340       350       360       370       380      
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
      340       350       360       370       380       390        

        390       400       410       420       430       440      
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
      400       410       420       430       440       450        

        450       460       470       480       490       500      
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
      460       470       480       490       500       510        

        510       520       530   
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::
XP_011 TDSLTSGATEKSRERSRDVKNSEGDCA
      520       530       540     

>>NP_001001582 (OMIM: 602973) high affinity cGMP-specifi  (552 aa)
 initn: 3265 init1: 3023 opt: 3024  Z-score: 3337.9  bits: 627.4 E(85289): 3.5e-179
Smith-Waterman score: 3149; 89.0% identity (89.0% similar) in 547 aa overlap (47-533:6-552)

         20        30        40        50        60        70      
pF1KB9 IDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPY
                                     ::::::::::::::::::::::::::::::
NP_001                          MDAFRRNTTISLLTTDDAMVSIDPTMPANSERTPY
                                        10        20        30     

         80                                                        
pF1KB9 KVRPVAIKQLS-------------------------------------------------
       :::::::::::                                                 
NP_001 KVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQ
          40        50        60        70        80        90     

                   90       100       110       120       130      
pF1KB9 -----------EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
                  :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVV
         100       110       120       130       140       150     

        140       150       160       170       180       190      
pF1KB9 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEAL
         160       170       180       190       200       210     

        200       210       220       230       240       250      
pF1KB9 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRH
         220       230       240       250       260       270     

        260       270       280       290       300       310      
pF1KB9 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYN
         280       290       300       310       320       330     

        320       330       340       350       360       370      
pF1KB9 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFK
         340       350       360       370       380       390     

        380       390       400       410       420       430      
pF1KB9 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGL
         400       410       420       430       440       450     

        440       450       460       470       480       490      
pF1KB9 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRI
         460       470       480       490       500       510     

        500       510       520       530   
pF1KB9 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::::::::::::
NP_001 DDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
         520       530       540       550  

>>NP_001001583 (OMIM: 602973) high affinity cGMP-specifi  (567 aa)
 initn: 3326 init1: 3023 opt: 3024  Z-score: 3337.7  bits: 627.4 E(85289): 3.6e-179
Smith-Waterman score: 3249; 88.3% identity (90.6% similar) in 565 aa overlap (3-533:3-567)

               10        20        30        40              50    
pF1KB9 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRN------TTISLL
         :::::::::::::::::::::::::::::::::::::::::::::.      ..:. :
NP_001 MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRTPYKVRPVAIKQL
               10        20        30        40        50        60

                              60         70        80              
pF1KB9 TT-------------------DDAMVSID-PTMPANSERTPYKVRPVAIKQL--------
       ..                   :  .:... :   .  :    . ::   .          
NP_001 SAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIP
               70        80        90       100       110       120

         90       100       110       120       130       140      
pF1KB9 SEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIK
              130       140       150       160       170       180

        150       160       170       180       190       200      
pF1KB9 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLW
              190       200       210       220       230       240

        210       220       230       240       250       260      
pF1KB9 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYS
              250       260       270       280       290       300

        270       280       290       300       310       320      
pF1KB9 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHC
              310       320       330       340       350       360

        330       340       350       360       370       380      
pF1KB9 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSN
              370       380       390       400       410       420

        390       400       410       420       430       440      
pF1KB9 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDK
              430       440       450       460       470       480

        450       460       470       480       490       500      
pF1KB9 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
              490       500       510       520       530       540

        510       520       530   
pF1KB9 TDSLTSGATEKSRERSRDVKNSEGDCA
       :::::::::::::::::::::::::::
NP_001 TDSLTSGATEKSRERSRDVKNSEGDCA
              550       560       




533 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 14:49:29 2016 done: Sat Nov  5 14:49:30 2016
 Total Scan time:  9.440 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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