Result of FASTA (omim) for pF1KB9909
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9909, 256 aa
  1>>>pF1KB9909 256 - 256 aa - 256 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2107+/-0.000319; mu= 15.0629+/- 0.020
 mean_var=73.6671+/-14.544, 0's: 0 Z-trim(117.1): 286  B-trim: 0 in 0/53
 Lambda= 0.149430
 statistics sampled from 28585 (28890) to 28585 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.339), width:  16
 Scan time:  7.090

The best scores are:                                      opt bits E(85289)
NP_002768 (OMIM: 177020) myeloblastin precursor [H ( 256) 1767 389.9 2.5e-108
XP_011526438 (OMIM: 177020) PREDICTED: myeloblasti ( 206) 1416 314.1 1.2e-85
XP_011526078 (OMIM: 130130,162800,202700) PREDICTE ( 267)  911 205.3   9e-53
XP_011526077 (OMIM: 130130,162800,202700) PREDICTE ( 267)  911 205.3   9e-53
NP_001963 (OMIM: 130130,162800,202700) neutrophil  ( 267)  911 205.3   9e-53
NP_001691 (OMIM: 162815) azurocidin preproprotein  ( 251)  657 150.5 2.6e-36
NP_001827 (OMIM: 118938) chymase isoform 1 preprop ( 247)  565 130.7 2.4e-30
NP_001902 (OMIM: 116830) cathepsin G preproprotein ( 255)  550 127.5 2.3e-29
NP_004122 (OMIM: 123910) granzyme B isoform 1 prep ( 247)  543 126.0 6.5e-29
NP_219491 (OMIM: 116831) granzyme H isoform 1 prep ( 246)  531 123.4 3.9e-28
NP_001332940 (OMIM: 123910) granzyme B isoform 2 [ ( 235)  516 120.1 3.5e-27
XP_011534801 (OMIM: 116830) PREDICTED: cathepsin G ( 269)  516 120.2 3.9e-27
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247)  489 114.3 2.1e-25
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240)  484 113.2 4.3e-25
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261)  484 113.3 4.6e-25
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304)  484 113.3 5.1e-25
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333)  484 113.3 5.5e-25
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247)  475 111.3 1.7e-24
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472)  475 111.5 2.8e-24
NP_002761 (OMIM: 167800,601564) trypsin-2 isoform  ( 247)  455 107.0 3.3e-23
NP_005568 (OMIM: 152200) apolipoprotein(a) precurs (2040)  452 107.0 2.7e-22
NP_002765 (OMIM: 602652) kallikrein-6 isoform A pr ( 244)  422 99.9 4.6e-21
NP_001012982 (OMIM: 602652) kallikrein-6 isoform A ( 244)  422 99.9 4.6e-21
NP_004908 (OMIM: 204700,603767) kallikrein-4 isofo ( 254)  390 93.0 5.6e-19
NP_006135 (OMIM: 140050) granzyme A precursor [Hom ( 262)  388 92.6 7.8e-19
NP_002095 (OMIM: 600784) granzyme K precursor [Hom ( 264)  371 88.9 9.9e-18
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810)  373 89.7 1.8e-17
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263)  363 87.2 3.3e-17
NP_005308 (OMIM: 600311) granzyme M isoform 1 prep ( 257)  358 86.1 6.8e-17
NP_001257709 (OMIM: 116831) granzyme H isoform 2 p ( 182)  356 85.6   7e-17
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268)  350 84.4 2.3e-16
NP_001919 (OMIM: 134350,613912) complement factor  ( 253)  349 84.2 2.6e-16
NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 pr ( 260)  348 83.9   3e-16
NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 pr ( 305)  345 83.3 5.4e-16
NP_001304264 (OMIM: 134350,613912) complement fact ( 260)  338 81.8 1.4e-15
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269)  337 81.6 1.6e-15
NP_036349 (OMIM: 609272) tryptase delta precursor  ( 242)  336 81.3 1.7e-15
NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267)  336 81.4 1.9e-15
NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267)  336 81.4 1.9e-15
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264)  333 80.7 2.9e-15
NP_001257710 (OMIM: 116831) granzyme H isoform 3 p ( 160)  325 78.8 6.5e-15
NP_001025218 (OMIM: 176820) prostate-specific anti ( 238)  327 79.4 6.6e-15
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269)  326 79.2 8.4e-15
XP_016878460 (OMIM: 610560) PREDICTED: polyserase- ( 621)  321 78.4 3.4e-14
NP_001070960 (OMIM: 605643) kallikrein-5 prepropro ( 293)  317 77.3 3.4e-14
XP_011525004 (OMIM: 605643) PREDICTED: kallikrein- ( 293)  317 77.3 3.4e-14
NP_001070959 (OMIM: 605643) kallikrein-5 prepropro ( 293)  317 77.3 3.4e-14
NP_036559 (OMIM: 605643) kallikrein-5 preproprotei ( 293)  317 77.3 3.4e-14
XP_011525005 (OMIM: 605643) PREDICTED: kallikrein- ( 293)  317 77.3 3.4e-14
XP_016878459 (OMIM: 610560) PREDICTED: polyserase- ( 634)  321 78.4 3.4e-14


>>NP_002768 (OMIM: 177020) myeloblastin precursor [Homo   (256 aa)
 initn: 1767 init1: 1767 opt: 1767  Z-score: 2066.0  bits: 389.9 E(85289): 2.5e-108
Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
              190       200       210       220       230       240

              250      
pF1KB9 DWIRSTLRRVEAKGRP
       ::::::::::::::::
NP_002 DWIRSTLRRVEAKGRP
              250      

>>XP_011526438 (OMIM: 177020) PREDICTED: myeloblastin is  (206 aa)
 initn: 1416 init1: 1416 opt: 1416  Z-score: 1658.3  bits: 314.1 E(85289): 1.2e-85
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
       ::::::::::::::::::::::::::                                  
XP_011 FCRPHNICTFVPRRKAGICFGDSGGP                                  
              190       200                                        

>>XP_011526078 (OMIM: 130130,162800,202700) PREDICTED: n  (267 aa)
 initn: 931 init1: 762 opt: 911  Z-score: 1068.4  bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)

                 10        20        30        40        50        
pF1KB9   MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
                  :: :: ::::.:.: :.:::::..:.::. :.:.:::.::.   ::::.
XP_011 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
               10        20        30        40        50          

       60        70        80        90       100       110        
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
       ::: :.::..::::. ..  : : :::::::.  .:::.: :.: ..: :.::  : :::
XP_011 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
        60        70        80        90       100       110       

      120       130       140       150       160       170        
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
       ....::.. :...:.: ..::: : . . .:.:::::::: .: .   :.::::::::::
XP_011 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
       120       130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
       : .::  :.::.:  :.::.::::::.::.:.:.:.:: :::  :::. :.:: :. :: 
XP_011 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
       180       190       200       210       220       230       

      240       250                  
pF1KB9 YVDWIRSTLRRVEAKGRP            
       .:.:: : ..: : .  :            
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
       240       250       260       

>>XP_011526077 (OMIM: 130130,162800,202700) PREDICTED: n  (267 aa)
 initn: 931 init1: 762 opt: 911  Z-score: 1068.4  bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)

                 10        20        30        40        50        
pF1KB9   MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
                  :: :: ::::.:.: :.:::::..:.::. :.:.:::.::.   ::::.
XP_011 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
               10        20        30        40        50          

       60        70        80        90       100       110        
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
       ::: :.::..::::. ..  : : :::::::.  .:::.: :.: ..: :.::  : :::
XP_011 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
        60        70        80        90       100       110       

      120       130       140       150       160       170        
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
       ....::.. :...:.: ..::: : . . .:.:::::::: .: .   :.::::::::::
XP_011 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
       120       130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
       : .::  :.::.:  :.::.::::::.::.:.:.:.:: :::  :::. :.:: :. :: 
XP_011 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
       180       190       200       210       220       230       

      240       250                  
pF1KB9 YVDWIRSTLRRVEAKGRP            
       .:.:: : ..: : .  :            
XP_011 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
       240       250       260       

>>NP_001963 (OMIM: 130130,162800,202700) neutrophil elas  (267 aa)
 initn: 931 init1: 762 opt: 911  Z-score: 1068.4  bits: 205.3 E(85289): 9e-53
Smith-Waterman score: 911; 54.7% identity (79.8% similar) in 247 aa overlap (10-256:12-255)

                 10        20        30        40        50        
pF1KB9   MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGG
                  :: :: ::::.:.: :.:::::..:.::. :.:.:::.::.   ::::.
NP_001 MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG---HFCGA
               10        20        30        40        50          

       60        70        80        90       100       110        
pF1KB9 TLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLND
       ::: :.::..::::. ..  : : :::::::.  .:::.: :.: ..: :.::  : :::
NP_001 TLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLND
        60        70        80        90       100       110       

      120       130       140       150       160       170        
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
       ....::.. :...:.: ..::: : . . .:.:::::::: .: .   :.::::::::::
NP_001 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV
       120       130       140       150       160       170       

      180       190       200       210       220       230        
pF1KB9 TFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
       : .::  :.::.:  :.::.::::::.::.:.:.:.:: :::  :::. :.:: :. :: 
NP_001 TSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQ
       180       190       200       210       220       230       

      240       250                  
pF1KB9 YVDWIRSTLRRVEAKGRP            
       .:.:: : ..: : .  :            
NP_001 FVNWIDSIIQRSEDNPCPHPRDPDPASRTH
       240       250       260       

>>NP_001691 (OMIM: 162815) azurocidin preproprotein [Hom  (251 aa)
 initn: 364 init1: 201 opt: 657  Z-score: 772.8  bits: 150.5 E(85289): 2.6e-36
Smith-Waterman score: 657; 43.6% identity (71.0% similar) in 241 aa overlap (9-247:8-243)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
               :: . :::   .:..   .::::..:.:.. :..::.:   : : :::::.:
NP_001  MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQ---NQGRHFCGGAL
                10        20        30        40           50      

               70        80        90        100       110         
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQE-PTQQHFSVAQVFLNNYDAENKLNDV
       ::  ::.::: :...    . .:::::...: .:  ..: ::....  :.:: ...:::.
NP_001 IHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
         60        70        80        90       100       110      

     120       130       140       150       160       170         
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
       .:.::.  :::..::. . :: :.  :  ::.: . :::   .    ..  . .::::. 
NP_001 MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTP
        120       130       140       150       160       170      

     180        190       200       210       220       230        
pF1KB9 F-FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVAL
          :::.:.:: :  :..::: ::.: ::.:.:. .:. :: .  :.    :::::::::
NP_001 EDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVAL
        180       190       200       210       220         230    

      240       250      
pF1KB9 YVDWIRSTLRRVEAKGRP
       . ::: ..:         
NP_001 FRDWIDGVLNNPGPGPA 
          240       250  

>>NP_001827 (OMIM: 118938) chymase isoform 1 preproprote  (247 aa)
 initn: 497 init1: 131 opt: 565  Z-score: 665.7  bits: 130.7 E(85289): 2.4e-30
Smith-Waterman score: 565; 40.4% identity (66.1% similar) in 245 aa overlap (14-248:8-245)

               10        20        30        40        50          
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPG-SHFCGGT
                    :: .:: . :.:.::.:: : .:::::::: :..  . : :.:::: 
NP_001       MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGF
                     10        20        30        40        50    

      60        70        80        90       100        110        
pF1KB9 LIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLND
       ::. .::::::::      : ..:.:::::.  .: : :.. : . : . .:.. .  .:
NP_001 LIRRNFVLTAAHC----AGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHD
           60            70        80        90       100       110

      120       130       140       150       160       170        
pF1KB9 VLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV
       ..:..:.  :.:. .:.:. .:.: . :: : .: . ::::.:.  : ...:::... ..
NP_001 IMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLM
              120       130       140       150       160       170

            180         190       200       210       220       230
pF1KB9 T------FFCRPHNI--CTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFP
              :    ::.  :.  ::.  .   :::::::.: :. ::: :.   : .    :
NP_001 DPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSY---GRSDAKPP
              180       190       200       210          220       

              240       250      
pF1KB9 DFFTRVALYVDWIRSTLRRVEAKGRP
         :::.. :  :: . :.        
NP_001 AVFTRISHYRPWINQILQAN      
       230       240             

>>NP_001902 (OMIM: 116830) cathepsin G preproprotein [Ho  (255 aa)
 initn: 586 init1: 240 opt: 550  Z-score: 648.1  bits: 127.5 E(85289): 2.3e-29
Smith-Waterman score: 550; 39.0% identity (69.9% similar) in 246 aa overlap (13-248:6-243)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
                   .:::.::  .:.:.::.::.:..:::::::: ::...  :.  ::: :
NP_001        MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFL
                      10        20        30        40        50   

               70        80        90       100        110         
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDV
       .. .::::::::  .     .::.:::::.. .: ::::... ... . .:. ..  ::.
NP_001 VREDFVLTAAHCWGSN----INVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDI
            60            70        80        90       100         

     120       130       140       150       160       170         
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTV--
       .:.:::  .  . .:  : ::. .. .  :: : . :::::. .   ...:.:... :  
NP_001 MLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRG-TDTLREVQLRVQR
     110       120       130       140       150        160        

           180          190       200       210       220       230
pF1KB9 ----VTFFCR--PH-NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFP
           . .:    :. .::.   :.. .   :::::::.:... .:: :.   : .. . :
NP_001 DRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSY---GKSSGVPP
      170       180       190       200       210          220     

              240       250          
pF1KB9 DFFTRVALYVDWIRSTLRRVEAKGRP    
       . ::::. .. :::.:.:            
NP_001 EVFTRVSSFLPWIRTTMRSFKLLDQMETPL
         230       240       250     

>>NP_004122 (OMIM: 123910) granzyme B isoform 1 prepropr  (247 aa)
 initn: 518 init1: 230 opt: 543  Z-score: 640.1  bits: 126.0 E(85289): 6.5e-29
Smith-Waterman score: 543; 38.7% identity (62.9% similar) in 248 aa overlap (13-249:6-246)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
                   .:::.::   : :.::.:::::.:::::::: :..  . . . ::: :
NP_004        MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFL
                      10        20        30        40        50   

               70        80        90       100        110         
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDV
       :. .::::::::        .::.:::::.. :::::: . : . .    :. .:  ::.
NP_004 IRDDFVLTAAHCW----GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDI
            60            70        80        90       100         

     120       130       140       150       160       170         
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
       .:.::   :. . .:  ..::..   :  :  : . :::...     ...:::...::  
NP_004 MLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQE
     110       120       130       140       150       160         

               180       190       200       210       220         
pF1KB9 ----------FFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLF
                 ..    ..:.  :. :     :::::::.:. . ::: :.   :  . . 
NP_004 DRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSY---GRNNGMP
     170       180       190       200       210          220      

     230       240       250      
pF1KB9 PDFFTRVALYVDWIRSTLRRVEAKGRP
       :   :.:. .: ::..:..:       
NP_004 PRACTKVSSFVHWIKKTMKRY      
        230       240             

>>NP_219491 (OMIM: 116831) granzyme H isoform 1 prepropr  (246 aa)
 initn: 518 init1: 231 opt: 531  Z-score: 626.1  bits: 123.4 E(85289): 3.9e-28
Smith-Waterman score: 531; 38.2% identity (61.4% similar) in 249 aa overlap (13-250:6-246)

               10        20        30        40        50        60
pF1KB9 MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
                   .:::.::. .: . ::.:::::.:::::::: .:.  . . . ::: :
NP_219        MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGIL
                      10        20        30        40        50   

               70        80        90       100        110         
pF1KB9 IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQ-VFLNNYDAENKLNDV
       .. .::::::::        .::.:::::.. :: ::: . : . .    :. .:  ::.
NP_219 VRKDFVLTAAHC----QGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDI
            60            70        80        90       100         

     120       130       140       150       160       170         
pF1KB9 LLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT
       .:.::   :. ...:  ..::..   :  :  : . ::: : . .  : .:::. .::  
NP_219 MLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYV-SMSTLATTLQEVLLTVQK
     110       120       130       140       150        160        

            180          190       200       210       220         
pF1KB9 -------F---FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLF
              :   . :  .::.  :..      :::::::.:  . ::: :.   :      
NP_219 DCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSY---GNKKGTP
      170       180       190       200       210          220     

     230       240       250      
pF1KB9 PDFFTRVALYVDWIRSTLRRVEAKGRP
       :  . .:. .. ::. :..:.      
NP_219 PGVYIKVSHFLPWIKRTMKRL      
         230       240            




256 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 14:48:26 2016 done: Sat Nov  5 14:48:27 2016
 Total Scan time:  7.090 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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