Result of FASTA (omim) for pF1KB6167
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6167, 649 aa
  1>>>pF1KB6167 649 - 649 aa - 649 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0513+/-0.000467; mu= 15.8759+/- 0.029
 mean_var=85.4507+/-16.593, 0's: 0 Z-trim(110.4): 115  B-trim: 332 in 1/48
 Lambda= 0.138745
 statistics sampled from 18648 (18770) to 18648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.22), width:  16
 Scan time:  9.390

The best scores are:                                      opt bits E(85289)
NP_116559 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 4277 866.8       0
NP_002898 (OMIM: 600537) ATP-dependent DNA helicas ( 649) 4277 866.8       0
XP_005253518 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8       0
XP_005253520 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8       0
XP_005253521 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8       0
XP_005253519 (OMIM: 600537) PREDICTED: ATP-depende ( 649) 4277 866.8       0
XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloo ( 979) 1156 242.2 6.8e-63
NP_001274177 (OMIM: 210900,604610) Bloom syndrome  (1042) 1156 242.2 7.2e-63
NP_001274176 (OMIM: 210900,604610) Bloom syndrome  (1286) 1156 242.2 8.6e-63
NP_001274175 (OMIM: 210900,604610) Bloom syndrome  (1417) 1156 242.3 9.3e-63
NP_000048 (OMIM: 210900,604610) Bloom syndrome pro (1417) 1156 242.3 9.3e-63
XP_006720695 (OMIM: 210900,604610) PREDICTED: Bloo ( 763) 1142 239.3 3.9e-62
NP_001003716 (OMIM: 603781) ATP-dependent DNA heli ( 410)  882 187.1 1.1e-46
NP_001003715 (OMIM: 603781) ATP-dependent DNA heli ( 435)  882 187.1 1.1e-46
XP_016880833 (OMIM: 603781) PREDICTED: ATP-depende ( 435)  882 187.1 1.1e-46
XP_005257880 (OMIM: 603781) PREDICTED: ATP-depende ( 549)  882 187.2 1.4e-46
NP_004250 (OMIM: 603781) ATP-dependent DNA helicas ( 991)  882 187.3 2.2e-46
XP_016880832 (OMIM: 603781) PREDICTED: ATP-depende ( 991)  882 187.3 2.2e-46
XP_005257875 (OMIM: 603781) PREDICTED: ATP-depende (1012)  882 187.3 2.3e-46
XP_011523784 (OMIM: 603781) PREDICTED: ATP-depende (1012)  882 187.3 2.3e-46
XP_011542941 (OMIM: 277700,604611) PREDICTED: Wern (1405)  841 179.2 8.8e-44
NP_000544 (OMIM: 277700,604611) Werner syndrome AT (1432)  841 179.2   9e-44
XP_011542942 (OMIM: 277700,604611) PREDICTED: Wern ( 899)  778 166.5 3.8e-40
XP_011520184 (OMIM: 210900,604610) PREDICTED: Bloo ( 907)  583 127.5 2.2e-28
XP_011515686 (OMIM: 218600,266280,268400,603780) P (1142)  386 88.1 1.9e-16
XP_016869488 (OMIM: 218600,266280,268400,603780) P (1224)  386 88.1 2.1e-16
XP_016869486 (OMIM: 218600,266280,268400,603780) P (1254)  386 88.1 2.1e-16
XP_016869490 (OMIM: 218600,266280,268400,603780) P ( 911)  254 61.6 1.4e-08
XP_016869489 (OMIM: 218600,266280,268400,603780) P ( 941)  254 61.6 1.5e-08
NP_004251 (OMIM: 218600,266280,268400,603780) ATP- (1208)  254 61.7 1.8e-08
XP_016869487 (OMIM: 218600,266280,268400,603780) P (1238)  254 61.7 1.9e-08
XP_016869485 (OMIM: 218600,266280,268400,603780) P (1263)  254 61.7 1.9e-08
XP_016869484 (OMIM: 218600,266280,268400,603780) P (1265)  254 61.7 1.9e-08
XP_016869483 (OMIM: 218600,266280,268400,603780) P (1288)  254 61.7 1.9e-08
XP_016869482 (OMIM: 218600,266280,268400,603780) P (1290)  254 61.7 1.9e-08
XP_016869481 (OMIM: 218600,266280,268400,603780) P (1295)  254 61.7 1.9e-08
XP_016869480 (OMIM: 218600,266280,268400,603780) P (1320)  254 61.7   2e-08
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439)  212 53.0 2.7e-06
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529)  212 53.1 3.1e-06
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529)  212 53.1 3.1e-06
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604)  212 53.1 3.5e-06
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648)  212 53.1 3.7e-06
NP_001243839 (OMIM: 606357) nucleolar RNA helicase ( 715)  209 52.5 6.1e-06
NP_004719 (OMIM: 606357) nucleolar RNA helicase 2  ( 783)  209 52.6 6.5e-06
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411)  203 51.2 8.7e-06
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729)  206 51.9 9.3e-06
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731)  206 51.9 9.4e-06
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455)  200 50.6 1.4e-05
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796)  198 50.4   3e-05
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614)  194 49.5 4.3e-05


>>NP_116559 (OMIM: 600537) ATP-dependent DNA helicase Q1  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>NP_002898 (OMIM: 600537) ATP-dependent DNA helicase Q1  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>XP_005253518 (OMIM: 600537) PREDICTED: ATP-dependent D  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>XP_005253520 (OMIM: 600537) PREDICTED: ATP-dependent D  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>XP_005253521 (OMIM: 600537) PREDICTED: ATP-dependent D  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>XP_005253519 (OMIM: 600537) PREDICTED: ATP-dependent D  (649 aa)
 initn: 4277 init1: 4277 opt: 4277  Z-score: 4629.0  bits: 866.8 E(85289):    0
Smith-Waterman score: 4277; 100.0% identity (100.0% similar) in 649 aa overlap (1-649:1-649)

               10        20        30        40        50        60
pF1KB6 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
              550       560       570       580       590       600

              610       620       630       640         
pF1KB6 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
              610       620       630       640         

>>XP_011520183 (OMIM: 210900,604610) PREDICTED: Bloom sy  (979 aa)
 initn: 1215 init1: 632 opt: 1156  Z-score: 1250.1  bits: 242.2 E(85289): 6.8e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:211-772)

             50        60        70        80        90       100  
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
                                     :: . ..  :... : :..::  :::.::.
XP_011 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
              190       200       210       220       230       240

            110       120       130       140       150       160  
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
       .. :.. :..:::::::::::::::  : : :.:: :: ::. ::.. : .: : ::.:.
XP_011 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
              250       260       270       280       290       300

            170       180       190       200       210       220  
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
       ....  ..  .. .. .:.  .::.:::::::  :. ..: ::. :: . ..:...::.:
XP_011 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
              310       320       330       340       350       360

            230       240       250       260       270       280  
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
       : :::::::: ::: ...:...::.. ...:::::. .:  :    : : .  .:. :::
XP_011 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
              370       380       390       400       410       420

             290       300       310       320       330       340 
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
       : :: :: . .::...  :  : .. :  ..  .::::::.:... . .. .::  :. :
XP_011 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
              430          440       450       460       470       

             350       360        370       380       390       400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
        ::::.:    .  :..:: . .  ::. ::.:::::::::::::::: :. ::.:.:::
XP_011 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
       480       490       500       510       520       530       

              410       420       430               440       450  
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
       ::::::::   . :.:.: . :. :.. ...::. :...        :: :: ::.::..
XP_011 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
       540       550       560       570       580       590       

            460        470           480       490       500       
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
       :::. .  .: :  .: . :.:     :::::: . .. ...:.  ....... : .  .
XP_011 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
       600       610       620       630       640       650       

       510                   520       530         540       550   
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
       . .  .:            :.: ..:. .::.. .:. .   .  :.. :... ......
XP_011 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
        660       670       680        690       700       710     

           560        570        580       590           600       
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
        : ::  ..:   .:.:. .: ::. .::.. ..  :.. .:.    :... :. ::   
XP_011 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
         720       730       740       750       760       770     

       610       620       630       640                           
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA                  
                                                                   
XP_011 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
         780       790       800       810       820       830     

>>NP_001274177 (OMIM: 210900,604610) Bloom syndrome prot  (1042 aa)
 initn: 1215 init1: 632 opt: 1156  Z-score: 1249.7  bits: 242.2 E(85289): 7.2e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:274-835)

             50        60        70        80        90       100  
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
                                     :: . ..  :... : :..::  :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
           250       260       270       280       290       300   

            110       120       130       140       150       160  
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
       .. :.. :..:::::::::::::::  : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
           310       320       330       340       350       360   

            170       180       190       200       210       220  
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
       ....  ..  .. .. .:.  .::.:::::::  :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
           370       380       390       400       410       420   

            230       240       250       260       270       280  
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
       : :::::::: ::: ...:...::.. ...:::::. .:  :    : : .  .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
           430       440       450       460       470       480   

             290       300       310       320       330       340 
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
       : :: :: . .::...  :  : .. :  ..  .::::::.:... . .. .::  :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
           490       500          510       520       530       540

             350       360        370       380       390       400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
        ::::.:    .  :..:: . .  ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
              550       560       570       580       590       600

              410       420       430               440       450  
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
       ::::::::   . :.:.: . :. :.. ...::. :...        :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
              610       620       630       640       650       660

            460        470           480       490       500       
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
       :::. .  .: :  .: . :.:     :::::: . .. ...:.  ....... : .  .
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
              670       680       690       700       710          

       510                   520       530         540       550   
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
       . .  .:            :.: ..:. .::.. .:. .   .  :.. :... ......
NP_001 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
     720       730       740       750        760       770        

           560        570        580       590           600       
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
        : ::  ..:   .:.:. .: ::. .::.. ..  :.. .:.    :... :. ::   
NP_001 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
      780       790       800       810       820       830        

       610       620       630       640                           
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA                  
                                                                   
NP_001 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
      840       850       860       870       880       890        

>>NP_001274176 (OMIM: 210900,604610) Bloom syndrome prot  (1286 aa)
 initn: 1215 init1: 632 opt: 1156  Z-score: 1248.3  bits: 242.2 E(85289): 8.6e-63
Smith-Waterman score: 1210; 42.5% identity (72.4% similar) in 445 aa overlap (73-502:649-1090)

             50        60        70        80        90       100  
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
                                     :: . ..  :... : :..::  :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
      620       630       640       650       660       670        

            110       120       130       140       150       160  
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
       .. :.. :..:::::::::::::::  : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
      680       690       700       710       720       730        

            170       180       190       200       210       220  
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
       ....  ..  .. .. .:.  .::.:::::::  :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
      740       750       760       770       780       790        

            230       240       250       260       270       280  
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
       : :::::::: ::: ...:...::.. ...:::::. .:  :    : : .  .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
      800       810       820       830       840       850        

             290       300       310       320       330       340 
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
       : :: :: . .::...  :  : .. :  ..  .::::::.:... . .. .::  :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
      860       870          880       890       900       910     

             350       360        370       380       390       400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
        ::::.:    .  :..:: . .  ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
         920       930       940       950       960       970     

              410       420       430               440       450  
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
       ::::::::   . :.:.: . :. :.. ...::. :...        :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
         980       990      1000      1010      1020      1030     

            460        470           480       490       500       
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
       :::. .  .: :  .: . :.:     :::::: . .. ...:.  .........     
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFVQEHSSSQ
        1040      1050      1060      1070      1080      1090     

       510       520       530       540       550       560       
pF1KB6 EKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATI
                                                                   
NP_001 GMRNIKHVGPSGRFTMNMLVDIFLESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYS
        1100      1110      1120      1130      1140      1150     

>>NP_001274175 (OMIM: 210900,604610) Bloom syndrome prot  (1417 aa)
 initn: 1215 init1: 632 opt: 1156  Z-score: 1247.7  bits: 242.3 E(85289): 9.3e-63
Smith-Waterman score: 1265; 38.1% identity (69.5% similar) in 567 aa overlap (73-604:649-1210)

             50        60        70        80        90       100  
pF1KB6 TKKIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV
                                     :: . ..  :... : :..::  :::.::.
NP_001 FSESIQNYTDKSAQNLASRNLKHERFQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINA
      620       630       640       650       660       670        

            110       120       130       140       150       160  
pF1KB6 TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
       .. :.. :..:::::::::::::::  : : :.:: :: ::. ::.. : .: : ::.:.
NP_001 ALLGEDCFILMPTGGGKSLCYQLPACVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLT
      680       690       700       710       720       730        

            170       180       190       200       210       220  
pF1KB6 ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVH
       ....  ..  .. .. .:.  .::.:::::::  :. ..: ::. :: . ..:...::.:
NP_001 GDKTDSEATNIYLQLSKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLARFVIDEAH
      740       750       760       770       780       790        

            230       240       250       260       270       280  
pF1KB6 CCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFN
       : :::::::: ::: ...:...::.. ...:::::. .:  :    : : .  .:. :::
NP_001 CVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQVFSMSFN
      800       810       820       830       840       850        

             290       300       310       320       330       340 
pF1KB6 RPNL-YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHA
       : :: :: . .::...  :  : .. :  ..  .::::::.:... . .. .::  :. :
NP_001 RHNLKYYVLPKKPKKVA-F--DCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAA
      860       870          880       890       900       910     

             350       360        370       380       390       400
pF1KB6 GAYHANLEPEDKTTVHRKW-SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQ
        ::::.:    .  :..:: . .  ::. ::.:::::::::::::::: :. ::.:.:::
NP_001 LAYHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQ
         920       930       940       950       960       970     

              410       420       430               440       450  
pF1KB6 ESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQK--------LYEMVSYCQNISK
       ::::::::   . :.:.: . :. :.. ...::. :...        :: :: ::.::..
NP_001 ESGRAGRDGEISHCLLFYTYHDVTRLKRLIMMEKDGNHHTRETHFNNLYSMVHYCENITE
         980       990      1000      1010      1020      1030     

            460        470           480       490       500       
pF1KB6 CRRVLMAQHFDEV-WNSEACNKM----CDNCCKDSAFERKNITEYCRDLIKILKQAEELN
       :::. .  .: :  .: . :.:     :::::: . .. ...:.  ....... : .  .
NP_001 CRRIQLLAYFGENGFNPDFCKKHPDVSCDNCCKTKDYKTRDVTDDVKSIVRFV-QEHSSS
        1040      1050      1060      1070      1080       1090    

       510                   520       530         540       550   
pF1KB6 EKLTPLK------------LIDSWMGKGAAKLRVAGVVAP--TLPREDLEKIIAHFLIQQ
       . .  .:            :.: ..:. .::.. .:. .   .  :.. :... ......
NP_001 QGMRNIKHVGPSGRFTMNMLVDIFLGSKSAKIQ-SGIFGKGSAYSRHNAERLFKKLILDK
         1100      1110      1120       1130      1140      1150   

           560        570        580       590           600       
pF1KB6 YLKEDYSFTAY-ATISYLKIGPKAN-LLNNEAHAITMQVTKST----QNSFRAESSQTCH
        : ::  ..:   .:.:. .: ::. .::.. ..  :.. .:.    :... :. ::   
NP_001 ILDEDLYINANDQAIAYVMLGNKAQTVLNGNLKVDFMETENSSSVKKQKALVAKVSQREE
          1160      1170      1180      1190      1200      1210   

       610       620       630       640                           
pF1KB6 SEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA                  
                                                                   
NP_001 MVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEK
          1220      1230      1240      1250      1260      1270   




649 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:39:07 2016 done: Sat Nov  5 13:39:08 2016
 Total Scan time:  9.390 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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