Result of FASTA (omim) for pF1KA0708
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0708, 2517 aa
  1>>>pF1KA0708 2517 - 2517 aa - 2517 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8052+/-0.000406; mu= 15.7000+/- 0.026
 mean_var=167.0189+/-33.685, 0's: 0 Z-trim(117.8): 148  B-trim: 308 in 1/53
 Lambda= 0.099241
 statistics sampled from 30055 (30211) to 30055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.354), width:  16
 Scan time: 22.310

The best scores are:                                      opt bits E(85289)
NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens]   (2517) 17077 2458.9       0
XP_011512730 (OMIM: 607489) PREDICTED: cullin-9 is (1851) 10282 1485.9       0
XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 10282 1486.0       0
XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1       0
XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1       0
XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 10282 1486.1       0
XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 is (1403) 9201 1331.1       0
XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 7091 1029.1       0
XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 6816 989.7       0
XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 6816 989.7       0
XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 6816 989.8       0
XP_011512726 (OMIM: 607489) PREDICTED: cullin-9 is (2539) 6816 989.8       0
NP_055595 (OMIM: 273750,609577) cullin-7 isoform 2 (1698) 3431 505.0 3.4e-141
XP_016867028 (OMIM: 273750,609577) PREDICTED: cull (1702) 3431 505.0 3.4e-141
XP_016867027 (OMIM: 273750,609577) PREDICTED: cull (1711) 3431 505.0 3.4e-141
XP_016867026 (OMIM: 273750,609577) PREDICTED: cull (1730) 3431 505.0 3.5e-141
XP_006715348 (OMIM: 273750,609577) PREDICTED: cull (1734) 3431 505.0 3.5e-141
XP_016867025 (OMIM: 273750,609577) PREDICTED: cull (1743) 3431 505.0 3.5e-141
XP_005249560 (OMIM: 273750,609577) PREDICTED: cull (1750) 3431 505.0 3.5e-141
XP_011513322 (OMIM: 273750,609577) PREDICTED: cull (1754) 3431 505.0 3.5e-141
XP_016867024 (OMIM: 273750,609577) PREDICTED: cull (1763) 3431 505.0 3.5e-141
NP_001161842 (OMIM: 273750,609577) cullin-7 isofor (1782) 3431 505.0 3.5e-141
XP_011513321 (OMIM: 273750,609577) PREDICTED: cull (1786) 3431 505.0 3.5e-141
XP_016867023 (OMIM: 273750,609577) PREDICTED: cull (1791) 3431 505.0 3.6e-141
XP_016867022 (OMIM: 273750,609577) PREDICTED: cull (1795) 3431 505.0 3.6e-141
XP_011513323 (OMIM: 273750,609577) PREDICTED: cull ( 989) 3051 450.4 5.4e-125
XP_016867029 (OMIM: 273750,609577) PREDICTED: cull ( 897) 1252 192.8 1.7e-47
XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493)  588 97.6 4.5e-19
NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493)  588 97.6 4.5e-19
NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493)  588 97.6 4.5e-19
XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493)  588 97.6 4.5e-19
XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409)  563 93.9 4.6e-18
XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409)  563 93.9 4.6e-18
XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  563 94.0 4.7e-18
XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  563 94.0 4.7e-18
XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  563 94.0 4.7e-18
XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  563 94.0 4.7e-18
XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421)  563 94.0 4.7e-18
NP_005735 (OMIM: 605624) E3 ubiquitin-protein liga ( 557)  517 87.5 5.6e-16
XP_011531567 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  496 84.4 4.3e-15
XP_011531568 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  496 84.4 4.3e-15
XP_011531570 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  496 84.4 4.3e-15
XP_011531569 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516)  496 84.4 4.3e-15
XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 465)  489 83.4 7.9e-15
NP_001304263 (OMIM: 605615) E3 ubiquitin-protein l ( 351)  474 81.2 2.8e-14
XP_011531575 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 432)  471 80.8 4.4e-14
XP_011531573 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  471 80.8 4.5e-14
XP_016861022 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  471 80.8 4.5e-14
XP_011531572 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  471 80.8 4.5e-14
XP_016861024 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444)  471 80.8 4.5e-14


>>NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens]        (2517 aa)
 initn: 17077 init1: 17077 opt: 17077  Z-score: 13212.5  bits: 2458.9 E(85289):    0
Smith-Waterman score: 17077; 100.0% identity (100.0% similar) in 2517 aa overlap (1-2517:1-2517)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHMSEQFARYIDQQIQGG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQ
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEE
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQN
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKD
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVA
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KA0 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSP
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KA0 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQ
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KA0 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEY
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KA0 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWC
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KA0 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMS
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KA0 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCS
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KA0 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLE
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KA0 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLL
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KA0 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGP
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510       
pF1KA0 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
             2470      2480      2490      2500      2510       

>>XP_011512730 (OMIM: 607489) PREDICTED: cullin-9 isofor  (1851 aa)
 initn: 10446 init1: 10282 opt: 10282  Z-score: 7956.5  bits: 1485.9 E(85289):    0
Smith-Waterman score: 11823; 97.3% identity (97.3% similar) in 1835 aa overlap (1-1786:1-1835)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540                    
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV
             1510      1520      1530      1540      1550      1560

                                          1550      1560      1570 
pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML
                                        :::::::::::::::::::::::::::
XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML
             1570      1580      1590      1600      1610      1620

            1580      1590      1600      1610      1620      1630 
pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
             1630      1640      1650      1660      1670      1680

            1640      1650      1660      1670      1680      1690 
pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
             1690      1700      1710      1720      1730      1740

            1700      1710      1720      1730      1740      1750 
pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
             1750      1760      1770      1780      1790      1800

            1760      1770      1780      1790      1800      1810 
pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
       :::::::::::::::::::::::::::::::::::                         
XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTESCCSRHSCPSPQGMAL         
             1810      1820      1830      1840      1850          

            1820      1830      1840      1850      1860      1870 
pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL

>>XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 isofor  (2339 aa)
 initn: 15611 init1: 10282 opt: 10282  Z-score: 7955.1  bits: 1486.0 E(85289):    0
Smith-Waterman score: 15397; 97.8% identity (97.9% similar) in 2334 aa overlap (1-2285:1-2334)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540                    
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV
             1510      1520      1530      1540      1550      1560

                                          1550      1560      1570 
pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML
                                        :::::::::::::::::::::::::::
XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML
             1570      1580      1590      1600      1610      1620

            1580      1590      1600      1610      1620      1630 
pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
             1630      1640      1650      1660      1670      1680

            1640      1650      1660      1670      1680      1690 
pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
             1690      1700      1710      1720      1730      1740

            1700      1710      1720      1730      1740      1750 
pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
             1750      1760      1770      1780      1790      1800

            1760      1770      1780      1790      1800      1810 
pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
             1810      1820      1830      1840      1850      1860

            1820      1830      1840      1850      1860      1870 
pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
             1870      1880      1890      1900      1910      1920

            1880      1890      1900      1910      1920      1930 
pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
             1930      1940      1950      1960      1970      1980

            1940      1950      1960      1970      1980      1990 
pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
             1990      2000      2010      2020      2030      2040

            2000      2010      2020      2030      2040      2050 
pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
             2050      2060      2070      2080      2090      2100

            2060      2070      2080      2090      2100      2110 
pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
             2110      2120      2130      2140      2150      2160

            2120      2130      2140      2150      2160      2170 
pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
             2170      2180      2190      2200      2210      2220

            2180      2190      2200      2210      2220      2230 
pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
             2230      2240      2250      2260      2270      2280

            2240      2250      2260      2270      2280      2290 
pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::: :.      
XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMPSQRILAR 
             2290      2300      2310      2320      2330          

            2300      2310      2320      2330      2340      2350 
pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV

>>XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 isofor  (2566 aa)
 initn: 10396 init1: 10282 opt: 10282  Z-score: 7954.5  bits: 1486.1 E(85289):    0
Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540                    
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV
             1510      1520      1530      1540      1550      1560

                                          1550      1560      1570 
pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML
                                        :::::::::::::::::::::::::::
XP_016 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML
             1570      1580      1590      1600      1610      1620

            1580      1590      1600      1610      1620      1630 
pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
             1630      1640      1650      1660      1670      1680

            1640      1650      1660      1670      1680      1690 
pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
             1690      1700      1710      1720      1730      1740

            1700      1710      1720      1730      1740      1750 
pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
             1750      1760      1770      1780      1790      1800

            1760      1770      1780      1790      1800      1810 
pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
             1810      1820      1830      1840      1850      1860

            1820      1830      1840      1850      1860      1870 
pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
             1870      1880      1890      1900      1910      1920

            1880      1890      1900      1910      1920      1930 
pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
             1930      1940      1950      1960      1970      1980

            1940      1950      1960      1970      1980      1990 
pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
             1990      2000      2010      2020      2030      2040

            2000      2010      2020      2030      2040      2050 
pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
             2050      2060      2070      2080      2090      2100

            2060      2070      2080      2090      2100      2110 
pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
             2110      2120      2130      2140      2150      2160

            2120      2130      2140      2150      2160      2170 
pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
             2170      2180      2190      2200      2210      2220

            2180      2190      2200      2210      2220      2230 
pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
             2230      2240      2250      2260      2270      2280

            2240      2250      2260      2270      2280      2290 
pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
             2290      2300      2310      2320      2330      2340

            2300      2310      2320      2330      2340      2350 
pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
             2350      2360      2370      2380      2390      2400

            2360      2370      2380      2390      2400      2410 
pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
             2410      2420      2430      2440      2450      2460

            2420      2430      2440      2450      2460      2470 
pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
             2470      2480      2490      2500      2510      2520

            2480      2490      2500      2510       
pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
       :::::::::::::::::::::::::::::                 
XP_016 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
             2530      2540      2550      2560      

>>XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 isofor  (2566 aa)
 initn: 10396 init1: 10282 opt: 10282  Z-score: 7954.5  bits: 1486.1 E(85289):    0
Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540                    
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV
             1510      1520      1530      1540      1550      1560

                                          1550      1560      1570 
pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML
                                        :::::::::::::::::::::::::::
XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML
             1570      1580      1590      1600      1610      1620

            1580      1590      1600      1610      1620      1630 
pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
             1630      1640      1650      1660      1670      1680

            1640      1650      1660      1670      1680      1690 
pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
             1690      1700      1710      1720      1730      1740

            1700      1710      1720      1730      1740      1750 
pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
             1750      1760      1770      1780      1790      1800

            1760      1770      1780      1790      1800      1810 
pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
             1810      1820      1830      1840      1850      1860

            1820      1830      1840      1850      1860      1870 
pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
             1870      1880      1890      1900      1910      1920

            1880      1890      1900      1910      1920      1930 
pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
             1930      1940      1950      1960      1970      1980

            1940      1950      1960      1970      1980      1990 
pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
             1990      2000      2010      2020      2030      2040

            2000      2010      2020      2030      2040      2050 
pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
             2050      2060      2070      2080      2090      2100

            2060      2070      2080      2090      2100      2110 
pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
             2110      2120      2130      2140      2150      2160

            2120      2130      2140      2150      2160      2170 
pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
             2170      2180      2190      2200      2210      2220

            2180      2190      2200      2210      2220      2230 
pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
             2230      2240      2250      2260      2270      2280

            2240      2250      2260      2270      2280      2290 
pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
             2290      2300      2310      2320      2330      2340

            2300      2310      2320      2330      2340      2350 
pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
             2350      2360      2370      2380      2390      2400

            2360      2370      2380      2390      2400      2410 
pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
             2410      2420      2430      2440      2450      2460

            2420      2430      2440      2450      2460      2470 
pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
             2470      2480      2490      2500      2510      2520

            2480      2490      2500      2510       
pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
       :::::::::::::::::::::::::::::                 
XP_011 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
             2530      2540      2550      2560      

>>XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 isofor  (2566 aa)
 initn: 10396 init1: 10282 opt: 10282  Z-score: 7954.5  bits: 1486.1 E(85289):    0
Smith-Waterman score: 16851; 98.1% identity (98.1% similar) in 2549 aa overlap (1-2500:1-2549)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPR
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540                    
pF1KA0 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAH----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 YCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQV
             1510      1520      1530      1540      1550      1560

                                          1550      1560      1570 
pF1KA0 ---------------------------------MSEQFARYIDQQIQGGLIGGAPGVEML
                                        :::::::::::::::::::::::::::
XP_011 HLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEML
             1570      1580      1590      1600      1610      1620

            1580      1590      1600      1610      1620      1630 
pF1KA0 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQ
             1630      1640      1650      1660      1670      1680

            1640      1650      1660      1670      1680      1690 
pF1KA0 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDP
             1690      1700      1710      1720      1730      1740

            1700      1710      1720      1730      1740      1750 
pF1KA0 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRR
             1750      1760      1770      1780      1790      1800

            1760      1770      1780      1790      1800      1810 
pF1KA0 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPL
             1810      1820      1830      1840      1850      1860

            1820      1830      1840      1850      1860      1870 
pF1KA0 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNL
             1870      1880      1890      1900      1910      1920

            1880      1890      1900      1910      1920      1930 
pF1KA0 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCIL
             1930      1940      1950      1960      1970      1980

            1940      1950      1960      1970      1980      1990 
pF1KA0 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQL
             1990      2000      2010      2020      2030      2040

            2000      2010      2020      2030      2040      2050 
pF1KA0 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLL
             2050      2060      2070      2080      2090      2100

            2060      2070      2080      2090      2100      2110 
pF1KA0 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVL
             2110      2120      2130      2140      2150      2160

            2120      2130      2140      2150      2160      2170 
pF1KA0 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILC
             2170      2180      2190      2200      2210      2220

            2180      2190      2200      2210      2220      2230 
pF1KA0 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKL
             2230      2240      2250      2260      2270      2280

            2240      2250      2260      2270      2280      2290 
pF1KA0 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEK
             2290      2300      2310      2320      2330      2340

            2300      2310      2320      2330      2340      2350 
pF1KA0 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACV
             2350      2360      2370      2380      2390      2400

            2360      2370      2380      2390      2400      2410 
pF1KA0 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMEL
             2410      2420      2430      2440      2450      2460

            2420      2430      2440      2450      2460      2470 
pF1KA0 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDED
             2470      2480      2490      2500      2510      2520

            2480      2490      2500      2510       
pF1KA0 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
       :::::::::::::::::::::::::::::                 
XP_011 DVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDEDEAYD
             2530      2540      2550      2560      

>>XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 isofor  (1403 aa)
 initn: 9201 init1: 9201 opt: 9201  Z-score: 7121.7  bits: 1331.1 E(85289):    0
Smith-Waterman score: 9201; 100.0% identity (100.0% similar) in 1386 aa overlap (1-1386:1-1386)

               10        20        30        40        50        60
pF1KA0 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVGERHAGDLMVPLGPRLQAYPEELIRQRPGHDGHPEYLIRWSVLKCGEVGKVGVEEGKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHILMWLSAPEVYANCPGLLGERALSKGLQHEPAGVSGSFPRDPGGLDEVAMGEMEADVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVRRAARQLAESGTPSLTAAVLHTIHVLSAYASIGPLTGVFRETGALDLLMHMLCNPEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIRRSAGKMLQALAAHDAGSRAHVLLSLSQQDGIEQHMDFDSRYTLLELFAETTSSEEHC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFEGIHLPQIPGKLLFSLVKRYLCVTSLLDQLNSSPELGAGDQSSPCATREKSRGQREL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFSMAVGNLISELVRSMGWARNLSEQGMSPPRPTRSIFQPYISGPSLLLPTIVTTPRRQG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVFRQRSEFSSRSGYGEYVQQTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGIPPVQVFW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTGRTYWVHWHMLEILGPEEATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPY
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPEPQKNERVGYLTQAEWWELLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEMAESLLQVLSSRFEGSTLNDLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASFSEEETESLKAKAEAPKTEAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEMARALRGPGPRSSLDQHVAAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRH
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVIT
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGST
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 QNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSP
       ::::::                                                      
XP_011 QNITSPGLSPQCSSLLPAPGTAP                                     
             1390      1400                                        

>>XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 isofor  (2095 aa)
 initn: 7205 init1: 7091 opt: 7091  Z-score: 5486.6  bits: 1029.1 E(85289):    0
Smith-Waterman score: 13660; 97.6% identity (97.6% similar) in 2078 aa overlap (472-2500:1-2078)

             450       460       470       480       490       500 
pF1KA0 ATEDKASAAVEKGAGATVLGTAFPSWDWNPMDGLYPLPYLQPEPQKNERVGYLTQAEWWE
                                     ::::::::::::::::::::::::::::::
XP_011                               MDGLYPLPYLQPEPQKNERVGYLTQAEWWE
                                             10        20        30

             510       520       530       540       550       560 
pF1KA0 LLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVSVEMAESLLQVLSSRFEGSTLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLFFIKKLDLCEQQPIFQNLWKNLDETLGEKALGEISVSVEMAESLLQVLSSRFEGSTLN
               40        50        60        70        80        90

             570       580       590       600       610       620 
pF1KA0 DLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLNSQIYTKYGLLSNEPSSSSTSRNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKT
              100       110       120       130       140       150

             630       640       650       660       670       680 
pF1KA0 EAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEPTKTRTETPMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHV
              160       170       180       190       200       210

             690       700       710       720       730       740 
pF1KA0 AAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAVVATVQISSLDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQ
              220       230       240       250       260       270

             750       760       770       780       790       800 
pF1KA0 VGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGEKMVVVQALRLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKML
              280       290       300       310       320       330

             810       820       830       840       850       860 
pF1KA0 AVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVASSSEIPTFVTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTE
              340       350       360       370       380       390

             870       880       890       900       910       920 
pF1KA0 GCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCSSAARNGLLLLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLL
              400       410       420       430       440       450

             930       940       950       960       970       980 
pF1KA0 NRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRYSEPPGSPERAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAV
              460       470       480       490       500       510

             990      1000      1010      1020      1030      1040 
pF1KA0 RPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPLLKRLQQETQPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCL
              520       530       540       550       560       570

            1050      1060      1070      1080      1090      1100 
pF1KA0 NCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCLSGPSSDSEIVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCEL
              580       590       600       610       620       630

            1110      1120      1130      1140      1150      1160 
pF1KA0 RDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLVTECEKYAQLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSS
              640       650       660       670       680       690

            1170      1180      1190      1200      1210      1220 
pF1KA0 VEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEVKEDKCWEKVEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLL
              700       710       720       730       740       750

            1230      1240      1250      1260      1270      1280 
pF1KA0 VASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASEDSSYMPARVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRC
              760       770       780       790       800       810

            1290      1300      1310      1320      1330      1340 
pF1KA0 QQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQGGIDTRVRGVEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCP
              820       830       840       850       860       870

            1350      1360      1370      1380      1390      1400 
pF1KA0 RLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLNRVLRHEQNFADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQY
              880       890       900       910       920       930

            1410      1420      1430      1440      1450      1460 
pF1KA0 LEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQRETSRNPLSRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPS
              940       950       960       970       980       990

            1470      1480      1490      1500      1510      1520 
pF1KA0 PVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLPSSSLRNITQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAA
             1000      1010      1020      1030      1040      1050

            1530      1540                                         
pF1KA0 FMLALRSGFSGALLQQSFLTAAH-------------------------------------
       :::::::::::::::::::::::                                     
XP_011 FMLALRSGFSGALLQQSFLTAAHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPS
             1060      1070      1080      1090      1100      1110

                     1550      1560      1570      1580      1590  
pF1KA0 ------------MSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATT
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMVCSCPFPCPQMSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATT
             1120      1130      1140      1150      1160      1170

           1600      1610      1620      1630      1640      1650  
pF1KA0 FEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEHFYQHYMADRLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQL
             1180      1190      1200      1210      1220      1230

           1660      1670      1680      1690      1700      1710  
pF1KA0 QRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRLDKLFLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCY
             1240      1250      1260      1270      1280      1290

           1720      1730      1740      1750      1760      1770  
pF1KA0 LYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYHPRKCLPTEFCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVS
             1300      1310      1320      1330      1340      1350

           1780      1790      1800      1810      1820      1830  
pF1KA0 TVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVL
             1360      1370      1380      1390      1400      1410

           1840      1850      1860      1870      1880      1890  
pF1KA0 RLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLHEPGPQRSGEALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQ
             1420      1430      1440      1450      1460      1470

           1900      1910      1920      1930      1940      1950  
pF1KA0 LVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVCLVLEAWQKGPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYA
             1480      1490      1500      1510      1520      1530

           1960      1970      1980      1990      2000      2010  
pF1KA0 APEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APEPMGPCRGQADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQ
             1540      1550      1560      1570      1580      1590

           2020      2030      2040      2050      2060      2070  
pF1KA0 VQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQETLNLEPDVAQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPV
             1600      1610      1620      1630      1640      1650

           2080      2090      2100      2110      2120      2130  
pF1KA0 CVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAI
             1660      1670      1680      1690      1700      1710

           2140      2150      2160      2170      2180      2190  
pF1KA0 VSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNC
             1720      1730      1740      1750      1760      1770

           2200      2210      2220      2230      2240      2250  
pF1KA0 SFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHM
             1780      1790      1800      1810      1820      1830

           2260      2270      2280      2290      2300      2310  
pF1KA0 TCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCAKCNHGFCWRCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVN
             1840      1850      1860      1870      1880      1890

           2320      2330      2340      2350      2360      2370  
pF1KA0 LRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRNRVSAIHEVPPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENL
             1900      1910      1920      1930      1940      1950

           2380      2390      2400      2410      2420      2430  
pF1KA0 ELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHTNALQILLEETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRV
             1960      1970      1980      1990      2000      2010

           2440      2450      2460      2470      2480      2490  
pF1KA0 GLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSY
             2020      2030      2040      2050      2060      2070

           2500      2510       
pF1KA0 DESENLDQETFFFGDEEEDEDEAYD
       ::::::::                 
XP_011 DESENLDQETFFFGDEEEDEDEAYD
             2080      2090     

>>XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 isofor  (1834 aa)
 initn: 6802 init1: 6802 opt: 6816  Z-score: 5274.6  bits: 989.7 E(85289):    0
Smith-Waterman score: 12111; 97.3% identity (97.3% similar) in 1834 aa overlap (733-2517:1-1834)

            710       720       730       740       750       760  
pF1KA0 SALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQALRLLYLLMTKH
                                     ::::::::::::::::::::::::::::::
XP_011                               MLVELLTNQVGEKMVVVQALRLLYLLMTKH
                                             10        20        30

            770       780       790       800       810       820  
pF1KA0 EWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTFVTGRDSIHSL
               40        50        60        70        80        90

            830       840       850       860       870       880  
pF1KA0 FDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLLLLNLLLCNHH
              100       110       120       130       140       150

            890       900       910       920       930       940  
pF1KA0 TLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPERAALETPIIQ
              160       170       180       190       200       210

            950       960       970       980       990      1000  
pF1KA0 GQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQETQPFLLLLRTL
              220       230       240       250       260       270

           1010      1020      1030      1040      1050      1060  
pF1KA0 DAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSEIVQELTCFLH
              280       290       300       310       320       330

           1070      1080      1090      1100      1110      1120  
pF1KA0 RLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYAQLYSNLTSSI
              340       350       360       370       380       390

           1130      1140      1150      1160      1170      1180  
pF1KA0 LAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEKVEVSSNPHRA
              400       410       420       430       440       450

           1190      1200      1210      1220      1230      1240  
pF1KA0 SKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPARVVVFGGDST
              460       470       480       490       500       510

           1250      1260      1270      1280      1290      1300  
pF1KA0 SCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRGVEVLGPKPTF
              520       530       540       550       560       570

           1310      1320      1330      1340      1350      1360  
pF1KA0 WPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQNFADRFLPDDE
              580       590       600       610       620       630

           1370      1380      1390      1400      1410      1420  
pF1KA0 AAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPLSRAASFASRV
              640       650       660       670       680       690

           1430      1440      1450      1460      1470      1480  
pF1KA0 RRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNITQCWLSVVQE
              700       710       720       730       740       750

           1490      1500      1510      1520      1530      1540  
pF1KA0 QVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSGALLQQSFLTA
              760       770       780       790       800       810

                                                            1550   
pF1KA0 AH-------------------------------------------------MSEQFARYI
       ::                                                 :::::::::
XP_011 AHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCPQMSEQFARYI
              820       830       840       850       860       870

          1560      1570      1580      1590      1600      1610   
pF1KA0 DQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMADRLLSFGSSWL
              880       890       900       910       920       930

          1620      1630      1640      1650      1660      1670   
pF1KA0 EGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDEEEKRLEEE
              940       950       960       970       980       990

          1680      1690      1700      1710      1720      1730   
pF1KA0 EEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTEFCDALDRFSS
             1000      1010      1020      1030      1040      1050

          1740      1750      1760      1770      1780      1790   
pF1KA0 FYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFNQTEEVSVETL
             1060      1070      1080      1090      1100      1110

          1800      1810      1820      1830      1840      1850   
pF1KA0 LKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSGEALWLIPPQA
             1120      1130      1140      1150      1160      1170

          1860      1870      1880      1890      1900      1910   
pF1KA0 YLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPGTLGH
             1180      1190      1200      1210      1220      1230

          1920      1930      1940      1950      1960      1970   
pF1KA0 TVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQADVPFCGSQS
             1240      1250      1260      1270      1280      1290

          1980      1990      2000      2010      2020      2030   
pF1KA0 ETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQHLLAHSHW
             1300      1310      1320      1330      1340      1350

          2040      2050      2060      2070      2080      2090   
pF1KA0 GAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDLPSLCCMHYCC
             1360      1370      1380      1390      1400      1410

          2100      2110      2120      2130      2140      2150   
pF1KA0 KSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEKALLRGYVES
             1420      1430      1440      1450      1460      1470

          2160      2170      2180      2190      2200      2210   
pF1KA0 CSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASCGHMSQWVDDG
             1480      1490      1500      1510      1520      1530

          2220      2230      2240      2250      2260      2270   
pF1KA0 GYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCWRCLKSWKPNH
             1540      1550      1560      1570      1580      1590

          2280      2290      2300      2310      2320      2330   
pF1KA0 KDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEVPPPRSFTFLN
             1600      1610      1620      1630      1640      1650

          2340      2350      2360      2370      2380      2390   
pF1KA0 DACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILLEETLLRCRDL
             1660      1670      1680      1690      1700      1710

          2400      2410      2420      2430      2440      2450   
pF1KA0 ASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQ
             1720      1730      1740      1750      1760      1770

          2460      2470      2480      2490      2500      2510   
pF1KA0 PQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETFFFGDEEEDED
             1780      1790      1800      1810      1820      1830

           
pF1KA0 EAYD
       ::::
XP_011 EAYD
           

>>XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 isofor  (1909 aa)
 initn: 6802 init1: 6802 opt: 6816  Z-score: 5274.4  bits: 989.7 E(85289):    0
Smith-Waterman score: 12545; 97.4% identity (97.4% similar) in 1904 aa overlap (663-2517:6-1909)

            640       650       660       670       680       690  
pF1KA0 PMAQSDSQLFNQLLVTEGMTLPTEMKEAASEMARALRGPGPRSSLDQHVAAVVATVQISS
                                     ::::::::::::::::::::::::::::::
XP_016                          MCLNIEMARALRGPGPRSSLDQHVAAVVATVQISS
                                        10        20        30     

            700       710       720       730       740       750  
pF1KA0 LDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTNLQLSGLSALSQAVEEVTERDHPLVRPDRSLREKLVKMLVELLTNQVGEKMVVVQAL
          40        50        60        70        80        90     

            760       770       780       790       800       810  
pF1KA0 RLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLYLLMTKHEWRPLFAREGGIYAVLVCMQEYKTSVLVQQAGLAALKMLAVASSSEIPTF
         100       110       120       130       140       150     

            820       830       840       850       860       870  
pF1KA0 VTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGRDSIHSLFDAQMTREIFASIDSATRPGSESLLLTVPAAVILMLNTEGCSSAARNGLL
         160       170       180       190       200       210     

            880       890       900       910       920       930  
pF1KA0 LLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLNLLLCNHHTLGDQIITQELRDTLFRHSGIAPRTEPMPTTRTILMMLLNRYSEPPGSPE
         220       230       240       250       260       270     

            940       950       960       970       980       990  
pF1KA0 RAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAALETPIIQGQDGSPELLIRSLVGGPSAELLLDLERVLCREGSPGGAVRPLLKRLQQET
         280       290       300       310       320       330     

           1000      1010      1020      1030      1040      1050  
pF1KA0 QPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFLLLLRTLDAPGPNKTLLLSVLRVITRLLDFPEAMVLPWHEVLEPCLNCLSGPSSDSE
         340       350       360       370       380       390     

           1060      1070      1080      1090      1100      1110  
pF1KA0 IVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVQELTCFLHRLASMHKDYAVVLCCLGAKEILSKVLDKHSAQLLLGCELRDLVTECEKYA
         400       410       420       430       440       450     

           1120      1130      1140      1150      1160      1170  
pF1KA0 QLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLYSNLTSSILAGCIQMVLGQIEDHRRTHQPINIPFFDVFLRHLCQGSSVEVKEDKCWEK
         460       470       480       490       500       510     

           1180      1190      1200      1210      1220      1230  
pF1KA0 VEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVSSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTLLVASEDSSYMPA
         520       530       540       550       560       570     

           1240      1250      1260      1270      1280      1290  
pF1KA0 RVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVVVFGGDSTSCIGTELNTVNVMPSASRVILLENLNRFWPIIQIRIKRCQQGGIDTRVRG
         580       590       600       610       620       630     

           1300      1310      1320      1330      1340      1350  
pF1KA0 VEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVLGPKPTFWPLFREQLCRRTCLFYTIRAQAWSRDIAEDHRRLLQLCPRLNRVLRHEQN
         640       650       660       670       680       690     

           1360      1370      1380      1390      1400      1410  
pF1KA0 FADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FADRFLPDDEAAQALGKTCWEALVSPLVQNITSPDAEGVSALGWLLDQYLEQRETSRNPL
         700       710       720       730       740       750     

           1420      1430      1440      1450      1460      1470  
pF1KA0 SRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAASFASRVRRLCHLLVHVEPPPGPSPEPSTRPFSKNSKGRDRSPAPSPVLPSSSLRNI
         760       770       780       790       800       810     

           1480      1490      1500      1510      1520      1530  
pF1KA0 TQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQCWLSVVQEQVSRFLAAAWRAPDFVPRYCKLYEHLQRAGSELFGPRAAFMLALRSGFSG
         820       830       840       850       860       870     

           1540                                                    
pF1KA0 ALLQQSFLTAAH------------------------------------------------
       ::::::::::::                                                
XP_016 ALLQQSFLTAAHVSPTSSPQGYKLVFQVHLFLLCPFTSFRSPVSYSTPSFMVCSCPFPCP
         880       890       900       910       920       930     

          1550      1560      1570      1580      1590      1600   
pF1KA0 -MSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMAD
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMSEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELATTFEHFYQHYMAD
         940       950       960       970       980       990     

          1610      1620      1630      1640      1650      1660   
pF1KA0 RLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLSFGSSWLEGAVLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQE
        1000      1010      1020      1030      1040      1050     

          1670      1680      1690      1700      1710      1720   
pF1KA0 DEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRKCLPTE
        1060      1070      1080      1090      1100      1110     

          1730      1740      1750      1760      1770      1780   
pF1KA0 FCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCDALDRFSSFYSQSQNHPVLDMGPHRRLQWTWLGRAELQFGKQILHVSTVQMWLLLKFN
        1120      1130      1140      1150      1160      1170     

          1790      1800      1810      1820      1830      1840   
pF1KA0 QTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLHEGQDFPHGGVLRLHEPGPQRSG
        1180      1190      1200      1210      1220      1230     

          1850      1860      1870      1880      1890      1900   
pF1KA0 EALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALWLIPPQAYLNVEKDEGRTLEQKRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQK
        1240      1250      1260      1270      1280      1290     

          1910      1920      1930      1940      1950      1960   
pF1KA0 GPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPNPPGTLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDRPQILMYAAPEPMGPCRGQ
        1300      1310      1320      1330      1340      1350     

          1970      1980      1990      2000      2010      2020   
pF1KA0 ADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADVPFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDV
        1360      1370      1380      1390      1400      1410     

          2030      2040      2050      2060      2070      2080   
pF1KA0 AQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQHLLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVRPDHCPVCVSPLGCDDDL
        1420      1430      1440      1450      1460      1470     

          2090      2100      2110      2120      2130      2140   
pF1KA0 PSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYE
        1480      1490      1500      1510      1520      1530     

          2150      2160      2170      2180      2190      2200   
pF1KA0 KALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGTTCSKCGWASCFNCSFPEAHYPASC
        1540      1550      1560      1570      1580      1590     

          2210      2220      2230      2240      2250      2260   
pF1KA0 GHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCW
        1600      1610      1620      1630      1640      1650     

          2270      2280      2290      2300      2310      2320   
pF1KA0 RCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCLKSWKPNHKDYYNCSAMVSKAARQEKRFQDYNERCTFHHQAREFAVNLRNRVSAIHEV
        1660      1670      1680      1690      1700      1710     

          2330      2340      2350      2360      2370      2380   
pF1KA0 PPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPRSFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMDVVEQQTENLELHTNALQILL
        1720      1730      1740      1750      1760      1770     

          2390      2400      2410      2420      2430      2440   
pF1KA0 EETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETLLRCRDLASSLRLLRADCLSTGMELLRRIQERLLAILQHSAQDFRVGLQSPSVEAWE
        1780      1790      1800      1810      1820      1830     

          2450      2460      2470      2480      2490      2500   
pF1KA0 AKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFDEELDNDSFSYDESENLDQETF
        1840      1850      1860      1870      1880      1890     

          2510       
pF1KA0 FFGDEEEDEDEAYD
       ::::::::::::::
XP_016 FFGDEEEDEDEAYD
        1900         




2517 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:27:02 2016 done: Sat Nov  5 13:27:05 2016
 Total Scan time: 22.310 Total Display time:  1.760

Function used was FASTA [36.3.4 Apr, 2011]
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