Result of FASTA (omim) for pF1KB5419
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5419, 318 aa
  1>>>pF1KB5419 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7963+/-0.000649; mu= 19.2565+/- 0.040
 mean_var=129.2299+/-36.948, 0's: 0 Z-trim(105.4): 599  B-trim: 849 in 1/48
 Lambda= 0.112822
 statistics sampled from 12831 (13570) to 12831 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.455), E-opt: 0.2 (0.159), width:  16
 Scan time:  6.770

The best scores are:                                      opt bits E(85289)
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 2063 348.3 1.3e-95
NP_001289608 (OMIM: 600445) adenosine receptor A3  ( 173) 1145 198.4 8.6e-51
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326)  859 152.3 1.2e-36
NP_001041695 (OMIM: 102775) adenosine receptor A1  ( 326)  859 152.3 1.2e-36
NP_001289607 (OMIM: 600445) adenosine receptor A3  ( 123)  714 128.1 9.4e-30
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258)  637 116.0 8.3e-26
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258)  637 116.0 8.3e-26
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258)  637 116.0 8.3e-26
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412)  582 107.4 5.3e-23
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412)  582 107.4 5.3e-23
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412)  582 107.4 5.3e-23
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412)  582 107.4 5.3e-23
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412)  582 107.4 5.3e-23
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332)  462 87.7 3.6e-17
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  404 78.3 2.6e-14
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  404 78.3 2.6e-14
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  404 78.4 2.7e-14
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  404 78.4 2.8e-14
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  404 78.4 2.8e-14
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  404 78.4 2.8e-14
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  404 78.4 2.8e-14
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  404 78.4 2.8e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478)  369 72.8 1.6e-12
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin  ( 528)  369 72.9 1.7e-12
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116)  347 68.3 8.7e-12
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229)  348 68.9 1.1e-11
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231)  348 68.9 1.1e-11
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349)  348 69.2 1.4e-11
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens]    ( 402)  345 68.8 2.1e-11
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422)  341 68.2 3.4e-11
NP_003958 (OMIM: 607405) trace amine-associated re ( 337)  332 66.6 8.4e-11
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin  ( 405)  330 66.4 1.2e-10
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489)  330 66.5 1.3e-10
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337)  328 65.9 1.3e-10
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin  ( 539)  330 66.5 1.4e-10
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382)  322 65.0 2.8e-10
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382)  322 65.0 2.8e-10
NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333)  318 64.3 4.1e-10
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362)  318 64.3 4.3e-10
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362)  318 64.3 4.3e-10
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic  ( 408)  316 64.1 5.7e-10
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350)  315 63.8 5.9e-10
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369)  313 63.5 7.6e-10
NP_778237 (OMIM: 608923) trace amine-associated re ( 345)  310 63.0   1e-09
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic  ( 460)  311 63.3 1.1e-09
NP_000729 (OMIM: 118510) muscarinic acetylcholine  ( 460)  311 63.3 1.1e-09
XP_005251990 (OMIM: 601909) PREDICTED: probable G- ( 349)  303 61.9 2.3e-09
NP_005285 (OMIM: 601909) probable G-protein couple ( 349)  303 61.9 2.3e-09
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328)  302 61.7 2.5e-09
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331)  302 61.7 2.5e-09


>>NP_000668 (OMIM: 600445) adenosine receptor A3 isoform  (318 aa)
 initn: 2063 init1: 2063 opt: 2063  Z-score: 1837.8  bits: 348.3 E(85289): 1.3e-95
Smith-Waterman score: 2063; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
              250       260       270       280       290       300

              310        
pF1KB5 VVCHPSDSLDTSIEKNSE
       ::::::::::::::::::
NP_000 VVCHPSDSLDTSIEKNSE
              310        

>>NP_001289608 (OMIM: 600445) adenosine receptor A3 isof  (173 aa)
 initn: 1145 init1: 1145 opt: 1145  Z-score: 1032.9  bits: 198.4 E(85289): 8.6e-51
Smith-Waterman score: 1145; 100.0% identity (100.0% similar) in 173 aa overlap (146-318:1-173)

         120       130       140       150       160       170     
pF1KB5 VRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMD
                                     ::::::::::::::::::::::::::::::
NP_001                               MFGWNMKLTSEYHRNVTFLSCQFVSVMRMD
                                             10        20        30

         180       190       200       210       220       230     
pF1KB5 YMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLV
               40        50        60        70        80        90

         240       250       260       270       280       290     
pF1KB5 LFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLL
              100       110       120       130       140       150

         300       310        
pF1KB5 ILKACVVCHPSDSLDTSIEKNSE
       :::::::::::::::::::::::
NP_001 ILKACVVCHPSDSLDTSIEKNSE
              160       170   

>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s  (326 aa)
 initn: 954 init1: 533 opt: 859  Z-score: 778.6  bits: 152.3 E(85289): 1.2e-36
Smith-Waterman score: 1010; 48.8% identity (78.9% similar) in 322 aa overlap (1-313:1-319)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
       :: . .:.. :   :: .:..:.: .. :::::: .::.: .:. .:: ::::::.::.:
NP_000 MPPSISAFQAA---YIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVA
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::.::.::::....:   .:..::...: .::.:..::..:::::::::::::. .::: 
NP_000 VGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
        60        70        80        90       100       110       

              130       140       150         160           170    
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRM
       :.: ::  .:.. ::..::.::::::::::   . :  .  : ..    ..:.: .:. :
NP_000 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
       120       130       140       150       160       170       

          180       190       200       210        220       230   
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLF
       .:::::.:..:.. ::..:  :::..::.::..:. ..: :. .   .::.:.: :::: 
NP_000 EYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLA
       180       190       200       210       220       230       

           240       250         260       270       280       290 
pF1KB5 LVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKE
       :.::::::::::: :.:::  :  . . :... :..:.:.:.:: :::::::..:.::. 
NP_000 LILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       240       250       260       270       280       290       

             300       310          
pF1KB5 TYLLILKACVVCHPSDSLDTSIEKNSE  
       :.: : .    :.:.  .: ..       
NP_000 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
       300       310       320      

>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom  (326 aa)
 initn: 954 init1: 533 opt: 859  Z-score: 778.6  bits: 152.3 E(85289): 1.2e-36
Smith-Waterman score: 1010; 48.8% identity (78.9% similar) in 322 aa overlap (1-313:1-319)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
       :: . .:.. :   :: .:..:.: .. :::::: .::.: .:. .:: ::::::.::.:
NP_001 MPPSISAFQAA---YIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVA
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::.::.::::....:   .:..::...: .::.:..::..:::::::::::::. .::: 
NP_001 VGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
        60        70        80        90       100       110       

              130       140       150         160           170    
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRM
       :.: ::  .:.. ::..::.::::::::::   . :  .  : ..    ..:.: .:. :
NP_001 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
       120       130       140       150       160       170       

          180       190       200       210        220       230   
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLF
       .:::::.:..:.. ::..:  :::..::.::..:. ..: :. .   .::.:.: :::: 
NP_001 EYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLA
       180       190       200       210       220       230       

           240       250         260       270       280       290 
pF1KB5 LVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKE
       :.::::::::::: :.:::  :  . . :... :..:.:.:.:: :::::::..:.::. 
NP_001 LILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
       240       250       260       270       280       290       

             300       310          
pF1KB5 TYLLILKACVVCHPSDSLDTSIEKNSE  
       :.: : .    :.:.  .: ..       
NP_001 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
       300       310       320      

>>NP_001289607 (OMIM: 600445) adenosine receptor A3 isof  (123 aa)
 initn: 714 init1: 714 opt: 714  Z-score: 655.2  bits: 128.1 E(85289): 9.4e-30
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_001 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVSSIS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
                                                                   
NP_001 PTL                                                         
                                                                   

>>XP_005244959 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 589 init1: 190 opt: 637  Z-score: 584.3  bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)

            90       100       110       120       130       140   
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
                                     :. ::: :.: ::  .:.. ::..::.:::
XP_005 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
             20        30        40        50        60        70  

           150         160           170       180       190       
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
       :::::::   . :  .  : ..    ..:.: .:. :.:::::.:..:.. ::..:  ::
XP_005 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
             80        90       100       110       120       130  

       200       210        220       230       240       250      
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
       :..::.::..:. ..: :. .   .::.:.: :::: :.::::::::::: :.:::  : 
XP_005 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
            140       150       160       170       180       190  

          260       270       280       290       300       310    
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
        . . :... :..:.:.:.:: :::::::..:.::. :.: : .    :.:.  .: .. 
XP_005 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
            200       210       220       230       240       250  

             
pF1KB5 KNSE  
             
XP_005 EERPDD
             

>>XP_016855831 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 589 init1: 190 opt: 637  Z-score: 584.3  bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)

            90       100       110       120       130       140   
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
                                     :. ::: :.: ::  .:.. ::..::.:::
XP_016 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
             20        30        40        50        60        70  

           150         160           170       180       190       
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
       :::::::   . :  .  : ..    ..:.: .:. :.:::::.:..:.. ::..:  ::
XP_016 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
             80        90       100       110       120       130  

       200       210        220       230       240       250      
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
       :..::.::..:. ..: :. .   .::.:.: :::: :.::::::::::: :.:::  : 
XP_016 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
            140       150       160       170       180       190  

          260       270       280       290       300       310    
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
        . . :... :..:.:.:.:: :::::::..:.::. :.: : .    :.:.  .: .. 
XP_016 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
            200       210       220       230       240       250  

             
pF1KB5 KNSE  
             
XP_016 EERPDD
             

>>XP_005244958 (OMIM: 102775) PREDICTED: adenosine recep  (258 aa)
 initn: 589 init1: 190 opt: 637  Z-score: 584.3  bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)

            90       100       110       120       130       140   
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
                                     :. ::: :.: ::  .:.. ::..::.:::
XP_005 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
             20        30        40        50        60        70  

           150         160           170       180       190       
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
       :::::::   . :  .  : ..    ..:.: .:. :.:::::.:..:.. ::..:  ::
XP_005 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
             80        90       100       110       120       130  

       200       210        220       230       240       250      
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
       :..::.::..:. ..: :. .   .::.:.: :::: :.::::::::::: :.:::  : 
XP_005 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
            140       150       160       170       180       190  

          260       270       280       290       300       310    
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
        . . :... :..:.:.:.:: :::::::..:.::. :.: : .    :.:.  .: .. 
XP_005 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
            200       210       220       230       240       250  

             
pF1KB5 KNSE  
             
XP_005 EERPDD
             

>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 770 init1: 474 opt: 582  Z-score: 534.0  bits: 107.4 E(85289): 5.3e-23
Smith-Waterman score: 811; 41.6% identity (75.4% similar) in 305 aa overlap (10-302:4-308)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
                ... .:::.:. :.. ::.:::::  .: :: .::..: ::.:::: ::::
NP_001       MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIA
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::::..:.::..: :.    ..:::..:..:..:..::.::::::.:::. ... .::. 
NP_001 VGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNG
           60        70        80        90       100       110    

              130       140       150       160             170    
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTF------LSCQFVSVMRM
       ..:  :    ...::..:: .:::::.:::     .  .: .       ..: : .:. :
NP_001 LVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPM
          120       130       140       150       160       170    

          180       190       200       210          220       230 
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSN---SKETGAFYGREFKTAKS
       .:::::.:.. ...::..: ..:: ::   : .:.   :.   .... .   .: ..:::
NP_001 NYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKS
          180       190       200       210       220       230    

             240       250          260       270       280        
pF1KB5 LFLVLFLFALSWLPLSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKK
       : ... :::: :::: ::::. .:  .   .:  ..:..:.:::.::..::..:::.:..
NP_001 LAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIRE
          240       250       260       270       280       290    

      290       300       310                                      
pF1KB5 FKETYLLILKACVVCHPSDSLDTSIEKNSE                              
       :..:.  :... :.                                              
NP_001 FRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHP
          300       310       320       330       340       350    

>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho  (412 aa)
 initn: 770 init1: 474 opt: 582  Z-score: 534.0  bits: 107.4 E(85289): 5.3e-23
Smith-Waterman score: 811; 41.6% identity (75.4% similar) in 305 aa overlap (10-302:4-308)

               10        20        30        40        50        60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
                ... .:::.:. :.. ::.:::::  .: :: .::..: ::.:::: ::::
NP_001       MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIA
                     10        20        30        40        50    

               70        80        90       100       110       120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
       ::::..:.::..: :.    ..:::..:..:..:..::.::::::.:::. ... .::. 
NP_001 VGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNG
           60        70        80        90       100       110    

              130       140       150       160             170    
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTF------LSCQFVSVMRM
       ..:  :    ...::..:: .:::::.:::     .  .: .       ..: : .:. :
NP_001 LVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPM
          120       130       140       150       160       170    

          180       190       200       210          220       230 
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSN---SKETGAFYGREFKTAKS
       .:::::.:.. ...::..: ..:: ::   : .:.   :.   .... .   .: ..:::
NP_001 NYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKS
          180       190       200       210       220       230    

             240       250          260       270       280        
pF1KB5 LFLVLFLFALSWLPLSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKK
       : ... :::: :::: ::::. .:  .   .:  ..:..:.:::.::..::..:::.:..
NP_001 LAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIRE
          240       250       260       270       280       290    

      290       300       310                                      
pF1KB5 FKETYLLILKACVVCHPSDSLDTSIEKNSE                              
       :..:.  :... :.                                              
NP_001 FRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHP
          300       310       320       330       340       350    




318 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:44:50 2016 done: Sat Nov  5 12:44:51 2016
 Total Scan time:  6.770 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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