Result of FASTA (omim) for pF1KE0914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0914, 257 aa
  1>>>pF1KE0914 257 - 257 aa - 257 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.4546+/-0.000265; mu= 5.7345+/- 0.017
 mean_var=123.1957+/-24.967, 0's: 0 Z-trim(123.3): 7  B-trim: 555 in 1/58
 Lambda= 0.115552
 statistics sampled from 42881 (42888) to 42881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.503), width:  16
 Scan time:  7.970

The best scores are:                                      opt bits E(85289)
NP_002458 (OMIM: 113970,190080) myc proto-oncogene ( 454) 1710 295.2 1.4e-79
XP_016859657 (OMIM: 164280,164840,189960) PREDICTE ( 464)  293 58.9 1.8e-08
NP_005369 (OMIM: 164280,164840,189960) N-myc proto ( 464)  293 58.9 1.8e-08
NP_001280157 (OMIM: 164280,164840,189960) N-myc pr ( 464)  293 58.9 1.8e-08
NP_005367 (OMIM: 164850) protein L-Myc isoform 2 [ ( 236)  187 41.1  0.0021
NP_001028254 (OMIM: 164850) protein L-Myc isoform  ( 394)  187 41.2  0.0033
NP_001028253 (OMIM: 164850) protein L-Myc isoform  ( 364)  177 39.6  0.0098


>>NP_002458 (OMIM: 113970,190080) myc proto-oncogene pro  (454 aa)
 initn: 1710 init1: 1710 opt: 1710  Z-score: 1549.7  bits: 295.2 E(85289): 1.4e-79
Smith-Waterman score: 1710; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:16-267)

                              10        20        30        40     
pF1KE0                MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
                      :::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL
               70        80        90       100       110       120

         110       120       130       140       150       160     
pF1KE0 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS
              190       200       210       220       230       240

         230       240       250                                   
pF1KE0 STESSPQGSPEPLVLHEETPPTTSSDSGGTRR                            
       :::::::::::::::::::::::::::                                 
NP_002 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG
              250       260       270       280       290       300

>>XP_016859657 (OMIM: 164280,164840,189960) PREDICTED: N  (464 aa)
 initn: 292 init1: 147 opt: 293  Z-score: 272.9  bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)

                    10        20        30        40        50     
pF1KE0      MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
                     .: ::..::.:: :: ::.. ::    .:   ::.  :::::::::
XP_016 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
               10        20        30         40            50     

          60        70           80        90       100       110  
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
       ::::::::::  .  :   ::.:  : . :  .:.  :   : :..  .    :::   :
XP_016 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
          60        70          80             90       100        

            120       130       140                  150       160 
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
             :        .:.::::::::::  ::   :::::        :.  :    .:.
XP_016 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
                    110       120       130       140       150    

              170           180       190       200        210     
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
        .:: :::.  .    ...    .:.  :.::.::.::::.:.:    .:   :  .. :
XP_016 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
          160       170       180       190       200       210    

         220       230       240       250                         
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR                  
        .:.  :  ..  ..: :.:                                        
XP_016 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
          220         230       240       250       260       270  

>>NP_005369 (OMIM: 164280,164840,189960) N-myc proto-onc  (464 aa)
 initn: 292 init1: 147 opt: 293  Z-score: 272.9  bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)

                    10        20        30        40        50     
pF1KE0      MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
                     .: ::..::.:: :: ::.. ::    .:   ::.  :::::::::
NP_005 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
               10        20        30         40            50     

          60        70           80        90       100       110  
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
       ::::::::::  .  :   ::.:  : . :  .:.  :   : :..  .    :::   :
NP_005 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
          60        70          80             90       100        

            120       130       140                  150       160 
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
             :        .:.::::::::::  ::   :::::        :.  :    .:.
NP_005 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
                    110       120       130       140       150    

              170           180       190       200        210     
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
        .:: :::.  .    ...    .:.  :.::.::.::::.:.:    .:   :  .. :
NP_005 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
          160       170       180       190       200       210    

         220       230       240       250                         
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR                  
        .:.  :  ..  ..: :.:                                        
NP_005 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
          220         230       240       250       260       270  

>>NP_001280157 (OMIM: 164280,164840,189960) N-myc proto-  (464 aa)
 initn: 292 init1: 147 opt: 293  Z-score: 272.9  bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)

                    10        20        30        40        50     
pF1KE0      MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
                     .: ::..::.:: :: ::.. ::    .:   ::.  :::::::::
NP_001 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
               10        20        30         40            50     

          60        70           80        90       100       110  
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
       ::::::::::  .  :   ::.:  : . :  .:.  :   : :..  .    :::   :
NP_001 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
          60        70          80             90       100        

            120       130       140                  150       160 
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
             :        .:.::::::::::  ::   :::::        :.  :    .:.
NP_001 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
                    110       120       130       140       150    

              170           180       190       200        210     
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
        .:: :::.  .    ...    .:.  :.::.::.::::.:.:    .:   :  .. :
NP_001 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
          160       170       180       190       200       210    

         220       230       240       250                         
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR                  
        .:.  :  ..  ..: :.:                                        
NP_001 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
          220         230       240       250       260       270  

>>NP_005367 (OMIM: 164850) protein L-Myc isoform 2 [Homo  (236 aa)
 initn: 258 init1: 132 opt: 187  Z-score: 182.0  bits: 41.1 E(85289): 0.0021
Smith-Waterman score: 264; 36.8% identity (51.0% similar) in 239 aa overlap (2-235:18-208)

                                10        20         30        40  
pF1KE0                 MPLNVSFT-NRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQP
                        ::.:.   ... :.:::: : :::  :  :.::..        
NP_005 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRST-------
               10        20        30        40        50          

             50        60        70        80        90       100  
pF1KE0 PAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMV
        ::::::::::::.:.:: ::    :: .:.  :  :    :  .   :.  :.:. :  
NP_005 -APSEDIWKKFELVPSPPTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESR
             60        70           80          90        100      

            110       120       130       140          150         
pF1KE0 TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDS
        .  :      :             :: .:::::::::  .:   ::..::   : :   
NP_005 GHSKGWGRNYAS-------------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---
        110                    120       130       140             

     160       170       180       190       200       210         
pF1KE0 GSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPS
       :.:  : .   : : ::          :  .:. . : ::..   ::. :   :.. :::
NP_005 GNPPKASAAPDC-TPSL----------EAGNPAPAAPCPLGE---PKTQAC--SGSESPS
     150       160                  170       180            190   

     220       230       240       250             
pF1KE0 SDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR      
        ::  .  : : .: :                            
NP_005 -DSGKDLPEPSKRGPPHGWPKLCPCLRSGIGSSQALGPSPPLFG
            200       210       220       230      

>>NP_001028254 (OMIM: 164850) protein L-Myc isoform 3 [H  (394 aa)
 initn: 258 init1: 132 opt: 187  Z-score: 178.5  bits: 41.2 E(85289): 0.0033
Smith-Waterman score: 255; 32.3% identity (53.4% similar) in 251 aa overlap (2-246:18-225)

                                10        20         30        40  
pF1KE0                 MPLNVSFT-NRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQP
                        ::.:.   ... :.:::: : :::  :  :.::..        
NP_001 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRST-------
               10        20        30        40        50          

             50        60        70        80        90       100  
pF1KE0 PAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMV
        ::::::::::::.:.:: ::    :: .:.  :  :    :  .   :.  :.:. :  
NP_001 -APSEDIWKKFELVPSPPTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESR
             60        70           80          90        100      

            110       120       130       140          150         
pF1KE0 TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDS
        .  :      :             :: .:::::::::  .:   ::..::   : :   
NP_001 GHSKGWGRNYAS-------------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---
        110                    120       130       140             

     160       170       180       190       200       210         
pF1KE0 GSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPS
       :.:  : .   :. :      : :.     .:. . : ::.. .. ..:....: . : .
NP_001 GNPPKASAAPDCTPS------LEAG-----NPAPAAPCPLGEPKT-QACSGSESPSDSEN
     150       160                  170       180        190       

     220       230        240       250                            
pF1KE0 SDSLLSSTESSPQ-GSPEPLVLHEETPPTTSSDSGGTRR                     
        .  . ..:.  . :  .:...  .. :                                
NP_001 EEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEE
       200       210       220       230       240       250       

>>NP_001028253 (OMIM: 164850) protein L-Myc isoform 1 [H  (364 aa)
 initn: 250 init1: 132 opt: 177  Z-score: 170.1  bits: 39.6 E(85289): 0.0098
Smith-Waterman score: 245; 32.8% identity (52.1% similar) in 238 aa overlap (14-246:1-195)

               10        20         30        40        50         
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTP
                    .:::: : :::  :  :.::..         ::::::::::::.:.:
NP_001              MDYDSYQHYFYDYDCGEDFYRS--------TAPSEDIWKKFELVPSP
                            10        20                30         

      60        70        80        90       100       110         
pF1KE0 PLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDP
       : ::    :: .:.  :  :    :  .   :.  :.:. :   .  :      :     
NP_001 PTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESRGHSKGWGRNYAS-----
      40           50          60         70        80             

     120       130       140          150       160       170      
pF1KE0 DDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDSGSPNPARGHSVCSTSSL
               :: .:::::::::  .:   ::..::   : :   :.:  : .   : : ::
NP_001 --------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---GNPPKASAAPDC-TPSL
               90       100       110           120       130      

        180       190       200       210       220       230      
pF1KE0 YLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQ-GSP
                 :  .:. . : ::.. .. ..:....: . : . .  . ..:.  . :  
NP_001 ----------EAGNPAPAAPCPLGEPKT-QACSGSESPSDSENEEIDVVTVEKRQSLGIR
                   140       150        160       170       180    

         240       250                                             
pF1KE0 EPLVLHEETPPTTSSDSGGTRR                                      
       .:...  .. :                                                 
NP_001 KPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAG
          190       200       210       220       230       240    




257 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:07:47 2016 done: Sat Nov  5 12:07:48 2016
 Total Scan time:  7.970 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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