Result of FASTA (omim) for pF1KB0405
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0405, 465 aa
  1>>>pF1KB0405 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2814+/-0.00032; mu= 14.3742+/- 0.020
 mean_var=119.2606+/-23.741, 0's: 0 Z-trim(119.4): 412  B-trim: 53 in 1/54
 Lambda= 0.117443
 statistics sampled from 32883 (33306) to 32883 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.391), width:  16
 Scan time:  9.700

The best scores are:                                      opt bits E(85289)
NP_002823 (OMIM: 176889) tyrosine-protein phosphat ( 465) 3242 560.2 4.1e-159
XP_016857425 (OMIM: 176889) PREDICTED: tyrosine-pr ( 464) 3224 557.2 3.4e-158
XP_011508121 (OMIM: 176889) PREDICTED: tyrosine-pr ( 511) 3036 525.4 1.4e-148
XP_016857424 (OMIM: 176889) PREDICTED: tyrosine-pr ( 510) 3018 522.3 1.2e-147
NP_542155 (OMIM: 176889) tyrosine-protein phosphat ( 399) 2599 451.2 2.3e-126
NP_001186726 (OMIM: 176889) tyrosine-protein phosp ( 434) 2588 449.4 8.9e-126
XP_016857426 (OMIM: 176889) PREDICTED: tyrosine-pr ( 359) 2451 426.1 7.5e-119
XP_011508125 (OMIM: 176889) PREDICTED: tyrosine-pr ( 311) 2141 373.5 4.4e-103
XP_011508122 (OMIM: 176889) PREDICTED: tyrosine-pr ( 400) 2130 371.8 1.9e-102
XP_011508123 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1887 330.6 4.4e-90
XP_011508124 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1887 330.6 4.4e-90
NP_570897 (OMIM: 602853) receptor-type tyrosine-pr ( 412) 1293 230.0 9.7e-60
NP_001193945 (OMIM: 602853) receptor-type tyrosine ( 451) 1293 230.0   1e-59
NP_001193944 (OMIM: 602853) receptor-type tyrosine ( 545) 1293 230.1 1.2e-59
XP_011536917 (OMIM: 602853) PREDICTED: receptor-ty ( 649) 1293 230.1 1.4e-59
NP_002840 (OMIM: 602853) receptor-type tyrosine-pr ( 657) 1293 230.1 1.4e-59
NP_001265168 (OMIM: 176879) tyrosine-protein phosp ( 509) 1134 203.1 1.5e-51
NP_001035059 (OMIM: 176879) tyrosine-protein phosp ( 533) 1134 203.1 1.5e-51
NP_001265165 (OMIM: 176879) tyrosine-protein phosp ( 533) 1134 203.1 1.5e-51
NP_001265167 (OMIM: 176879) tyrosine-protein phosp ( 541) 1134 203.1 1.5e-51
NP_008837 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1134 203.2 1.6e-51
NP_116170 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1134 203.2 1.6e-51
XP_011508126 (OMIM: 176889) PREDICTED: tyrosine-pr ( 235) 1104 197.7 2.8e-50
XP_011518713 (OMIM: 176879) PREDICTED: tyrosine-pr ( 553) 1001 180.6 9.4e-45
XP_016873929 (OMIM: 176879) PREDICTED: tyrosine-pr ( 527)  658 122.5 2.8e-27
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377)  653 121.5   4e-27
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377)  653 121.5   4e-27
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405)  653 121.5 4.2e-27
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405)  653 121.5 4.2e-27
XP_016875213 (OMIM: 176882) PREDICTED: receptor-ty (1446)  657 122.7 6.7e-27
NP_001193900 (OMIM: 176882) receptor-type tyrosine (1907)  657 122.8 8.2e-27
NP_001193901 (OMIM: 176882) receptor-type tyrosine (1907)  657 122.8 8.2e-27
NP_002828 (OMIM: 176882) receptor-type tyrosine-pr (1997)  657 122.8 8.5e-27
XP_006719592 (OMIM: 176882) PREDICTED: receptor-ty (2012)  657 122.8 8.6e-27
NP_001317133 (OMIM: 176882) receptor-type tyrosine (2127)  657 122.8 8.9e-27
XP_011536916 (OMIM: 176882) PREDICTED: receptor-ty (2142)  657 122.8   9e-27
NP_001103224 (OMIM: 176882) receptor-type tyrosine (2215)  657 122.8 9.2e-27
XP_006719591 (OMIM: 176882) PREDICTED: receptor-ty (2230)  657 122.9 9.2e-27
NP_002839 (OMIM: 600579,614196) receptor-type tyro (1188)  653 121.9 9.3e-27
NP_109592 (OMIM: 600579,614196) receptor-type tyro (1216)  653 121.9 9.4e-27
NP_563578 (OMIM: 151460,608971,609532) receptor-ty (1145)  647 120.9 1.8e-26
XP_006711537 (OMIM: 151460,608971,609532) PREDICTE (1192)  647 120.9 1.9e-26
XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436)  648 121.2 1.9e-26
XP_006711536 (OMIM: 151460,608971,609532) PREDICTE (1240)  647 120.9 1.9e-26
XP_006711535 (OMIM: 151460,608971,609532) PREDICTE (1258)  647 120.9   2e-26
NP_002829 (OMIM: 151460,608971,609532) receptor-ty (1306)  647 121.0   2e-26
XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368)  646 120.8 2.3e-26
NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439)  646 120.8 2.4e-26
NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440)  646 120.8 2.4e-26
NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441)  646 120.8 2.4e-26


>>NP_002823 (OMIM: 176889) tyrosine-protein phosphatase   (465 aa)
 initn: 3242 init1: 3242 opt: 3242  Z-score: 2977.5  bits: 560.2 E(85289): 4.1e-159
Smith-Waterman score: 3242; 99.6% identity (99.8% similar) in 465 aa overlap (1-465:1-465)

               10        20        30        40        50        60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
       ::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
NP_002 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
              370       380       390       400       410       420

              430       440       450       460     
pF1KB0 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
       :::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
              430       440       450       460     

>>XP_016857425 (OMIM: 176889) PREDICTED: tyrosine-protei  (464 aa)
 initn: 1785 init1: 1785 opt: 3224  Z-score: 2961.1  bits: 557.2 E(85289): 3.4e-158
Smith-Waterman score: 3224; 99.4% identity (99.6% similar) in 465 aa overlap (1-465:1-464)

               10        20        30        40        50        60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
       ::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 RTAGHPLTRWALQRQPPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
              190       200        210       220       230         

              250       260       270       280       290       300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
     360       370       380       390       400       410         

              430       440       450       460     
pF1KB0 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
     420       430       440       450       460    

>>XP_011508121 (OMIM: 176889) PREDICTED: tyrosine-protei  (511 aa)
 initn: 3228 init1: 3036 opt: 3036  Z-score: 2788.4  bits: 525.4 E(85289): 1.4e-148
Smith-Waterman score: 3045; 90.3% identity (90.5% similar) in 497 aa overlap (1-451:1-497)

               10        20        30        40        50        60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
       ::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
              370       380       390       400       410       420

              430                                                  
pF1KB0 EVDILGIVCQLRLDR---------------------------------------------
       :::::::::::::::                                             
XP_011 EVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQH
              430       440       450       460       470       480

          440       450       460     
pF1KB0 -GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
        ::::::::::::::::              
XP_011 VGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
              490       500       510 

>>XP_016857424 (OMIM: 176889) PREDICTED: tyrosine-protei  (510 aa)
 initn: 1771 init1: 1579 opt: 3018  Z-score: 2771.9  bits: 522.3 E(85289): 1.2e-147
Smith-Waterman score: 3027; 90.1% identity (90.3% similar) in 497 aa overlap (1-451:1-496)

               10        20        30        40        50        60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
       ::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 RTAGHPLTRWALQRQPPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
              190       200        210       220       230         

              250       260       270       280       290       300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB0 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARG
     360       370       380       390       400       410         

              430                                                  
pF1KB0 EVDILGIVCQLRLDR---------------------------------------------
       :::::::::::::::                                             
XP_016 EVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQH
     420       430       440       450       460       470         

          440       450       460     
pF1KB0 -GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
        ::::::::::::::::              
XP_016 VGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
     480       490       500       510

>>NP_542155 (OMIM: 176889) tyrosine-protein phosphatase   (399 aa)
 initn: 2597 init1: 2597 opt: 2599  Z-score: 2389.6  bits: 451.2 E(85289): 2.3e-126
Smith-Waterman score: 2599; 96.7% identity (98.0% similar) in 394 aa overlap (72-465:9-399)

              50        60        70        80        90       100 
pF1KB0 QLGCAWVAARRGGGRKLASWSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPA
                                     ::.   :. : .   ..:::::::::::::
NP_542                       MGASFWPIRQAREQQRRALS---FRQTSWLSEPPLGPA
                                     10        20           30     

             110       120       130       140       150       160 
pF1KB0 PHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLG
          40        50        60        70        80        90     

             170       180       190       200       210       220 
pF1KB0 AVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDI
         100       110       120       130       140       150     

             230       240       250       260       270       280 
pF1KB0 PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTV
         160       170       180       190       200       210     

             290       300       310       320       330       340 
pF1KB0 SDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQL
         220       230       240       250       260       270     

             350       360       370       380       390       400 
pF1KB0 TIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIG
         280       290       300       310       320       330     

             410       420       430       440       450       460 
pF1KB0 RTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPE
         340       350       360       370       380       390     

           
pF1KB0 EPSP
       ::::
NP_542 EPSP
           

>>NP_001186726 (OMIM: 176889) tyrosine-protein phosphata  (434 aa)
 initn: 2588 init1: 2588 opt: 2588  Z-score: 2379.1  bits: 449.4 E(85289): 8.9e-126
Smith-Waterman score: 2594; 90.1% identity (92.8% similar) in 433 aa overlap (42-465:3-434)

              20        30        40             50         60     
pF1KB0 QGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVA-----ARRGGG-RKLASWSLLS
                                     .::: : :     . ::.: :.:.  .  :
NP_001                             MNRLGC-WPARSLPRSGRGSGQRSLGLGGHPS
                                            10        20        30 

            70        80         90       100       110       120  
pF1KB0 PQRQ--TDRQTDSWQEAAWGPQLLQ-QTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLS
         :.  :     .:.  .   .    .:::::::::::::::::::::::::::::::::
NP_001 GPRHPGTPAAKRTWESPGVRARDCPLSTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLS
              40        50        60        70        80        90 

            130       140       150       160       170       180  
pF1KB0 LGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRT
             100       110       120       130       140       150 

            190       200       210       220       230       240  
pF1KB0 AGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVC
             160       170       180       190       200       210 

            250       260       270       280       290       300  
pF1KB0 LGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL
             220       230       240       250       260       270 

            310       320       330       340       350       360  
pF1KB0 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPD
             280       290       300       310       320       330 

            370       380       390       400       410       420  
pF1KB0 HQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEV
             340       350       360       370       380       390 

            430       440       450       460     
pF1KB0 DILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 DILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
             400       410       420       430    

>>XP_016857426 (OMIM: 176889) PREDICTED: tyrosine-protei  (359 aa)
 initn: 1785 init1: 1785 opt: 2451  Z-score: 2254.7  bits: 426.1 E(85289): 7.5e-119
Smith-Waterman score: 2451; 99.7% identity (99.7% similar) in 360 aa overlap (106-465:1-359)

          80        90       100       110       120       130     
pF1KB0 SWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKT
                                     ::::::::::::::::::::::::::::::
XP_016                               MVQAHGGRSRAQPLTLSLGAAMTQPPPEKT
                                             10        20        30

         140       150       160       170       180       190     
pF1KB0 PAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQ
               40        50        60        70        80        90

         200       210       220       230       240       250     
pF1KB0 PPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI
       :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPKQLEEEFL-IPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYI
              100        110       120       130       140         

         260       270       280       290       300       310     
pF1KB0 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPT
     150       160       170       180       190       200         

         320       330       340       350       360       370     
pF1KB0 EEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRL
     210       220       230       240       250       260         

         380       390       400       410       420       430     
pF1KB0 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR
     270       280       290       300       310       320         

         440       450       460     
pF1KB0 GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
       ::::::::::::::::::::::::::::::
XP_016 GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
     330       340       350         

>>XP_011508125 (OMIM: 176889) PREDICTED: tyrosine-protei  (311 aa)
 initn: 2141 init1: 2141 opt: 2141  Z-score: 1971.7  bits: 373.5 E(85289): 4.4e-103
Smith-Waterman score: 2141; 99.3% identity (99.7% similar) in 307 aa overlap (1-307:1-307)

               10        20        30        40        50        60
pF1KB0 MVGKAWPLTHSQGMGPWAPEGHRREAADPWWQRQQAREGRMQLGCAWVAARRGGGRKLAS
       ::::::::::::: ::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 MVGKAWPLTHSQGTGPWAPEGHRREAADPWWQRQQAQEGRMQLGCAWVAARRGGGRKLAS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSLLSPQRQTDRQTDSWQEAAWGPQLLQQTSWLSEPPLGPAPHLSMVQAHGGRSRAQPLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAW
       :::::::                                                     
XP_011 QLREGKELPPS                                                 
              310                                                  

>>XP_011508122 (OMIM: 176889) PREDICTED: tyrosine-protei  (400 aa)
 initn: 2322 init1: 2130 opt: 2130  Z-score: 1960.1  bits: 371.8 E(85289): 1.9e-102
Smith-Waterman score: 2139; 87.4% identity (87.6% similar) in 372 aa overlap (126-451:15-386)

         100       110       120       130       140       150     
pF1KB0 PPLGPAPHLSMVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALML
                                     .:::::::::::::::::::::::::::::
XP_011                 MGVPWCEGQRLSTVSMTQPPPEKTPAKKHVRLQERRGSNVALML
                               10        20        30        40    

         160       170       180       190       200       210     
pF1KB0 DVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVS
           50        60        70        80        90       100    

         220       230       240       250       260       270     
pF1KB0 PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQG
          110       120       130       140       150       160    

         280       290       300       310       320       330     
pF1KB0 PMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPE
          170       180       190       200       210       220    

         340       350       360       370       380       390     
pF1KB0 YTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVH
          230       240       250       260       270       280    

         400       410       420       430                         
pF1KB0 CSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
XP_011 CSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRLLERRKLEAQEYSWPDPRLQ
          290       300       310       320       330       340    

                                   440       450       460     
pF1KB0 --------------------------GGMIQTAEQYQFLHHTLALYAGQLPEEPSP
                                 ::::::::::::::::              
XP_011 RSGFVPGAEWIKEDQVSTWGITPQHVGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
          350       360       370       380       390       400

>>XP_011508123 (OMIM: 176889) PREDICTED: tyrosine-protei  (354 aa)
 initn: 2079 init1: 1887 opt: 1887  Z-score: 1738.3  bits: 330.6 E(85289): 4.4e-90
Smith-Waterman score: 1896; 86.2% identity (86.2% similar) in 334 aa overlap (164-451:7-340)

           140       150       160       170       180       190   
pF1KB0 KTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQ
                                     ::::::::::::::::::::::::::::::
XP_011                         MCDCRREPICSVNTPREVTLHFLRTAGHPLTRWALQ
                                       10        20        30      

           200       210       220       230       240       250   
pF1KB0 RQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGD
         40        50        60        70        80        90      

           260       270       280       290       300       310   
pF1KB0 YINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYW
        100       110       120       130       140       150      

           320       330       340       350       360       370   
pF1KB0 PTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLL
        160       170       180       190       200       210      

           380       390       400       410       420       430   
pF1KB0 RLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL
        220       230       240       250       260       270      

                                                         440       
pF1KB0 DR----------------------------------------------GGMIQTAEQYQF
       ::                                              ::::::::::::
XP_011 DRLLERRKLEAQEYSWPDPRLQRSGFVPGAEWIKEDQVSTWGITPQHVGGMIQTAEQYQF
        280       290       300       310       320       330      

       450       460     
pF1KB0 LHHTLALYAGQLPEEPSP
       ::::              
XP_011 LHHTLALYAGQLPEEPSP
        340       350    




465 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:50:43 2016 done: Sat Nov  5 11:50:44 2016
 Total Scan time:  9.700 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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