Result of FASTA (omim) for pF1KB6684
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6684, 456 aa
  1>>>pF1KB6684 456 - 456 aa - 456 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1200+/-0.000367; mu= 18.7031+/- 0.023
 mean_var=69.4937+/-13.724, 0's: 0 Z-trim(114.0): 35  B-trim: 0 in 0/54
 Lambda= 0.153851
 statistics sampled from 23508 (23543) to 23508 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.276), width:  16
 Scan time:  9.080

The best scores are:                                      opt bits E(85289)
NP_056984 (OMIM: 607460) phospholipase A1 member A ( 456) 3095 696.2 4.6e-200
NP_001280154 (OMIM: 607460) phospholipase A1 membe ( 440) 2904 653.8 2.6e-187
NP_001193889 (OMIM: 607460) phospholipase A1 membe ( 440) 2070 468.7 1.4e-131
XP_016862061 (OMIM: 607460) PREDICTED: phospholipa ( 283) 1934 438.4 1.2e-122
NP_001193890 (OMIM: 607460) phospholipase A1 membe ( 283) 1934 438.4 1.2e-122
NP_640341 (OMIM: 604379,607365) lipase member H pr ( 451)  891 207.0 8.5e-53
NP_001289930 (OMIM: 145750,609252) lipase member I ( 375)  878 204.1 5.4e-52
NP_945347 (OMIM: 145750,609252) lipase member I is ( 481)  867 201.7 3.6e-51
XP_006724028 (OMIM: 145750,609252) PREDICTED: lipa ( 404)  861 200.3 7.8e-51
NP_001289927 (OMIM: 145750,609252) lipase member I ( 460)  861 200.4 8.7e-51
XP_011510833 (OMIM: 604379,607365) PREDICTED: lipa ( 408)  857 199.4 1.5e-50
XP_011510832 (OMIM: 604379,607365) PREDICTED: lipa ( 408)  857 199.4 1.5e-50
NP_001289929 (OMIM: 145750,609252) lipase member I ( 454)  832 193.9 7.5e-49
XP_006713592 (OMIM: 604379,607365) PREDICTED: lipa ( 421)  537 128.4 3.6e-29
NP_001289928 (OMIM: 145750,609252) lipase member I ( 430)  507 121.8 3.7e-27
NP_006024 (OMIM: 603684) endothelial lipase isofor ( 500)  506 121.6 4.9e-27
NP_005387 (OMIM: 604423) pancreatic lipase-related ( 470)  501 120.5   1e-26
XP_005258447 (OMIM: 603684) PREDICTED: endothelial ( 536)  486 117.2 1.1e-25
NP_000927 (OMIM: 246600,614338) pancreatic triacyl ( 465)  467 112.9 1.9e-24
XP_011524569 (OMIM: 603684) PREDICTED: endothelial ( 420)  446 108.2 4.3e-23
NP_006220 (OMIM: 604422) inactive pancreatic lipas ( 467)  420 102.5 2.6e-21
XP_011538170 (OMIM: 604422) PREDICTED: inactive pa ( 467)  420 102.5 2.6e-21
NP_001290064 (OMIM: 604422) inactive pancreatic li ( 467)  420 102.5 2.6e-21
NP_000228 (OMIM: 144250,238600,609708) lipoprotein ( 475)  414 101.2 6.6e-21
XP_016871828 (OMIM: 604423) PREDICTED: pancreatic  ( 249)  400 97.8 3.4e-20
NP_000227 (OMIM: 125853,151670,612797,614025) hepa ( 499)  386 95.0 5.1e-19
XP_005254429 (OMIM: 125853,151670,612797,614025) P ( 499)  386 95.0 5.1e-19
XP_016861341 (OMIM: 604379,607365) PREDICTED: lipa ( 417)  385 94.7 5.1e-19
XP_016877665 (OMIM: 125853,151670,612797,614025) P ( 398)  383 94.2 6.7e-19
XP_005254431 (OMIM: 125853,151670,612797,614025) P ( 511)  383 94.3 8.2e-19
XP_006720565 (OMIM: 125853,151670,612797,614025) P ( 452)  381 93.8   1e-18
XP_016881584 (OMIM: 603684) PREDICTED: endothelial ( 303)  303 76.4 1.2e-13
NP_001294935 (OMIM: 603684) endothelial lipase iso ( 426)  267 68.5   4e-11
XP_011538171 (OMIM: 604422) PREDICTED: inactive pa ( 318)  259 66.6 1.1e-10
XP_011524567 (OMIM: 603684) PREDICTED: endothelial ( 462)  247 64.1 9.2e-10


>>NP_056984 (OMIM: 607460) phospholipase A1 member A iso  (456 aa)
 initn: 3095 init1: 3095 opt: 3095  Z-score: 3712.7  bits: 696.2 E(85289): 4.6e-200
Smith-Waterman score: 3095; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)

               10        20        30        40        50        60
pF1KB6 MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 WIYGSTGVYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WIYGSTGVYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
              370       380       390       400       410       420

              430       440       450      
pF1KB6 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
       ::::::::::::::::::::::::::::::::::::
NP_056 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
              430       440       450      

>>NP_001280154 (OMIM: 607460) phospholipase A1 member A   (440 aa)
 initn: 2904 init1: 2904 opt: 2904  Z-score: 3483.8  bits: 653.8 E(85289): 2.6e-187
Smith-Waterman score: 2904; 100.0% identity (100.0% similar) in 432 aa overlap (25-456:9-440)

               10        20        30        40        50        60
pF1KB6 MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
                               ::::::::::::::::::::::::::::::::::::
NP_001                 MHKSSSIWGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
                               10        20        30        40    

               70        80        90       100       110       120
pF1KB6 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB6 WIYGSTGVYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIYGSTGVYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFG
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB6 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB6 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB6 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB6 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
          350       360       370       380       390       400    

              430       440       450      
pF1KB6 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
       ::::::::::::::::::::::::::::::::::::
NP_001 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
          410       420       430       440

>>NP_001193889 (OMIM: 607460) phospholipase A1 member A   (440 aa)
 initn: 2070 init1: 2070 opt: 2070  Z-score: 2483.3  bits: 468.7 E(85289): 1.4e-131
Smith-Waterman score: 2965; 96.5% identity (96.5% similar) in 456 aa overlap (1-456:1-440)

               10        20        30        40        50        60
pF1KB6 MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 WIYGSTGVYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFG
       ::::::::::::::::                ::::::::::::::::::::::::::::
NP_001 WIYGSTGVYFSAVKNV----------------LGVSESSIHIIGVSLGAHVGGMVGQLFG
              130                       140       150       160    

              190       200       210       220       230       240
pF1KB6 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQ
          170       180       190       200       210       220    

              250       260       270       280       290       300
pF1KB6 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPF
          230       240       250       260       270       280    

              310       320       330       340       350       360
pF1KB6 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVT
          290       300       310       320       330       340    

              370       380       390       400       410       420
pF1KB6 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
          350       360       370       380       390       400    

              430       440       450      
pF1KB6 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
       ::::::::::::::::::::::::::::::::::::
NP_001 TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
          410       420       430       440

>>XP_016862061 (OMIM: 607460) PREDICTED: phospholipase A  (283 aa)
 initn: 1934 init1: 1934 opt: 1934  Z-score: 2322.9  bits: 438.4 E(85289): 1.2e-122
Smith-Waterman score: 1934; 100.0% identity (100.0% similar) in 283 aa overlap (174-456:1-283)

           150       160       170       180       190       200   
pF1KB6 SLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEE
                                     ::::::::::::::::::::::::::::::
XP_016                               MVGQLFGGQLGQITGLDPAGPEYTRASVEE
                                             10        20        30

           210       220       230       240       250       260   
pF1KB6 RLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRA
               40        50        60        70        80        90

           270       280       290       300       310       320   
pF1KB6 VHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKE
              100       110       120       130       140       150

           330       340       350       360       370       380   
pF1KB6 VKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKG
              160       170       180       190       200       210

           390       400       410       420       430       440   
pF1KB6 IIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQA
              220       230       240       250       260       270

           450      
pF1KB6 SVTVSCDLKIACV
       :::::::::::::
XP_016 SVTVSCDLKIACV
              280   

>>NP_001193890 (OMIM: 607460) phospholipase A1 member A   (283 aa)
 initn: 1934 init1: 1934 opt: 1934  Z-score: 2322.9  bits: 438.4 E(85289): 1.2e-122
Smith-Waterman score: 1934; 100.0% identity (100.0% similar) in 283 aa overlap (174-456:1-283)

           150       160       170       180       190       200   
pF1KB6 SLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEE
                                     ::::::::::::::::::::::::::::::
NP_001                               MVGQLFGGQLGQITGLDPAGPEYTRASVEE
                                             10        20        30

           210       220       230       240       250       260   
pF1KB6 RLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRA
               40        50        60        70        80        90

           270       280       290       300       310       320   
pF1KB6 VHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKE
              100       110       120       130       140       150

           330       340       350       360       370       380   
pF1KB6 VKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKG
              160       170       180       190       200       210

           390       400       410       420       430       440   
pF1KB6 IIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVCLPEPVNLQA
              220       230       240       250       260       270

           450      
pF1KB6 SVTVSCDLKIACV
       :::::::::::::
NP_001 SVTVSCDLKIACV
              280   

>>NP_640341 (OMIM: 604379,607365) lipase member H precur  (451 aa)
 initn: 751 init1: 622 opt: 891  Z-score: 1068.9  bits: 207.0 E(85289): 8.5e-53
Smith-Waterman score: 891; 35.4% identity (69.1% similar) in 404 aa overlap (23-416:14-411)

               10        20        30         40        50         
pF1KB6 MPPGPWESCFWVGGLILWLSVGSSGDAPPT-PQPKCADFQSANLFEGTDLKVQFLLFVPS
                             : .::  : :.    .:.:: .  :: :.:...:.. .
NP_640          MLRFYLFISLLCLSRSDAEETCPSFTRLSFHSAVV--GTGLNVRLMLYTRK
                        10        20        30          40         

      60        70        80        90       100       110         
pF1KB6 NPSCGQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAV
       : .:.: .. :: . :  .:.:  : .:.::::  :. : :.: ... :: . . ::..:
NP_640 NLTCAQTIN-SSAFGN--LNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVV
      50         60          70        80        90       100      

     120        130       140       150       160       170        
pF1KB6 DWIYGSTG-VYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQL
       ::  :.:  .:  : ... :... .. :....:. :.: ..:..::::::::..:.::..
NP_640 DWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEM
        110       120       130       140       150       160      

      180       190       200       210       220       230        
pF1KB6 FGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNG
       . : ::.::::::::: ..    ..::: .:: ::..::.::: :: . :.:..:.. ::
NP_640 YDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNG
        170       180       190       200       210       220      

      240       250       260       270       280       290        
pF1KB6 GQDQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFN
       : ::::::  . .:..:. :::.:.:.::.:.:..:: . :.:: ::. .  :.:..: .
NP_640 GLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGT
        230       240       250       260       270       280      

      300       310          320       330       340         350   
pF1KB6 PFLLSCPRIGLVE---QGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHL--KELRNK
           ::: .:      .  .. .  :  .:... :.  .:.::.: .:..    :..:  
NP_640 SQKESCPLLGYYADNWKDHLRGKD-PPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRG
        290       300       310        320       330       340     

           360       370        380        390        400       410
pF1KB6 DTNIEVTFLSSNITSSSKITIPKQ-QRYGK-GIIAHATPQC-QINQVKFKFQSSNRVWKK
       : .:..   ..: : :.    :   :.: . ...:. . .  ..  ... :.... .  .
NP_640 DITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFSTGSLIGPR
         350       360       370       380       390       400     

              420       430       440       450      
pF1KB6 DRTTIIGKFCTALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV
        .  :.                                        
NP_640 YKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPELQL
         410       420       430       440       450 

>>NP_001289930 (OMIM: 145750,609252) lipase member I iso  (375 aa)
 initn: 817 init1: 652 opt: 878  Z-score: 1054.4  bits: 204.1 E(85289): 5.4e-52
Smith-Waterman score: 878; 42.3% identity (73.9% similar) in 307 aa overlap (53-351:45-350)

             30        40        50        60         70        80 
pF1KB6 SSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSNPSCGQ-LVEGSSDLQNSGFNAT
                                     ..... .: .:.. : : ...: : .::. 
NP_001 SDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSL-NVNFNTQ
           20        30        40        50        60         70   

              90       100       110       120        130       140
pF1KB6 LGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVDWIYGSTG-VYFSAVKNVIKLS
         :  .:::.: .:. : :...:.: ::   . :::.:::  :.:  .:  ::::. :..
NP_001 KKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVA
            80        90       100       110       120       130   

              150       160       170       180       190       200
pF1KB6 LEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRAS
       . .:. ...::  :.: ...:.::::::::..:.::..: ::::.:::::::::...:  
NP_001 VSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKP
           140       150       160       170       180       190   

              210       220       230       240       250       260
pF1KB6 VEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDH
          :::  :: ::..::.:...:::. :.::.:.. :::. :::::  ...: ... :.:
NP_001 PYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNH
           200       210       220       230       240       250   

              270       280       290       300       310          
pF1KB6 MRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQ--GGV---
       .:::::....::..: ...::: ::: . .. :.::      ::::.:   .   ::   
NP_001 QRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKE
           260       270       280       290       300       310   

         320       330       340        350       360       370    
pF1KB6 KIEPLPKEVKVYLLTTSSAPYCMHH-SLVEFHLKELRNKDTNIEVTFLSSNITSSSKITI
       ..:  : .. :.: :... :.: :: . . ..::  :                       
NP_001 RMEGRPLRTTVFLDTSGTYPFCNHHFAGIILYLKTERKCFLIQTHVHQRTHKMPSSIKCT
           320       330       340       350       360       370   

          380       390       400       410       420       430    
pF1KB6 PKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFCTALLPVNDREKMVC
                                                                   
NP_001 CL                                                          
                                                                   

>>NP_945347 (OMIM: 145750,609252) lipase member I isofor  (481 aa)
 initn: 817 init1: 652 opt: 867  Z-score: 1039.7  bits: 201.7 E(85289): 3.6e-51
Smith-Waterman score: 867; 39.6% identity (70.7% similar) in 338 aa overlap (16-340:26-359)

                         10        20        30        40          
pF1KB6           MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEG-TDL
                                .::: :    .    :   : .:.. .. ..  ::
NP_945 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCLRSDNKRP---CLEFSQLSVKDSFRDL
               10        20        30        40           50       

      50             60         70        80        90       100   
pF1KB6 KVQ-----FLLFVPSNPSCGQ-LVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDT
        .      ..... .: .:.. : : ...: : .::.   :  .:::.: .:. : :...
NP_945 FIPRIETILMMYTRNNLNCAEPLFEQNNSL-NVNFNTQKKTVWLIHGYRPVGSIPLWLQN
        60        70        80         90       100       110      

           110       120        130       140       150       160  
pF1KB6 FIRTLLRATNANVIAVDWIYGSTG-VYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHI
       :.: ::   . :::.:::  :.:  .:  ::::. :... .:. ...::  :.: ...:.
NP_945 FVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHF
        120       130       140       150       160       170      

            170       180       190       200       210       220  
pF1KB6 IGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDN
       ::::::::..:.::..: ::::.:::::::::...:     :::  :: ::..::.:...
NP_945 IGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNG
        180       190       200       210       220       230      

            230       240       250       260       270       280  
pF1KB6 LGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPC
       :::. :.::.:.. :::. :::::  ...: ... :.:.:::::....::..: ...:::
NP_945 LGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPC
        240       250       260       270       280       290      

            290       300       310            320       330       
pF1KB6 ASYKAFLAGRCLDCFNPFLLSCPRIGLVEQ--GGV---KIEPLPKEVKVYLLTTSSAPYC
        ::: . .. :.::      ::::.:   .   ::   ..:  : .. :.: :... :.:
NP_945 RSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFC
        300       310       320       330       340       350      

       340       350       360       370       380       390       
pF1KB6 MHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQV
        ..                                                         
NP_945 TYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFV
        360       370       380       390       400       410      

>>XP_006724028 (OMIM: 145750,609252) PREDICTED: lipase m  (404 aa)
 initn: 817 init1: 652 opt: 861  Z-score: 1033.6  bits: 200.3 E(85289): 7.8e-51
Smith-Waterman score: 861; 42.4% identity (74.6% similar) in 295 aa overlap (53-340:74-367)

             30        40        50        60         70        80 
pF1KB6 SSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSNPSCGQ-LVEGSSDLQNSGFNAT
                                     ..... .: .:.. : : ...: : .::. 
XP_006 SDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSL-NVNFNTQ
            50        60        70        80        90        100  

              90       100       110       120        130       140
pF1KB6 LGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVDWIYGSTG-VYFSAVKNVIKLS
         :  .:::.: .:. : :...:.: ::   . :::.:::  :.:  .:  ::::. :..
XP_006 KKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVA
            110       120       130       140       150       160  

              150       160       170       180       190       200
pF1KB6 LEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRAS
       . .:. ...::  :.: ...:.::::::::..:.::..: ::::.:::::::::...:  
XP_006 VSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKP
            170       180       190       200       210       220  

              210       220       230       240       250       260
pF1KB6 VEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDH
          :::  :: ::..::.:...:::. :.::.:.. :::. :::::  ...: ... :.:
XP_006 PYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNH
            230       240       250       260       270       280  

              270       280       290       300       310          
pF1KB6 MRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQ--GGV---
       .:::::....::..: ...::: ::: . .. :.::      ::::.:   .   ::   
XP_006 QRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKE
            290       300       310       320       330       340  

         320       330       340       350       360       370     
pF1KB6 KIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIP
       ..:  : .. :.: :... :.: ..                                   
XP_006 RMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYE
            350       360       370       380       390       400  

>>NP_001289927 (OMIM: 145750,609252) lipase member I iso  (460 aa)
 initn: 817 init1: 652 opt: 861  Z-score: 1032.8  bits: 200.4 E(85289): 8.7e-51
Smith-Waterman score: 861; 42.4% identity (74.6% similar) in 295 aa overlap (53-340:45-338)

             30        40        50        60         70        80 
pF1KB6 SSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSNPSCGQ-LVEGSSDLQNSGFNAT
                                     ..... .: .:.. : : ...: : .::. 
NP_001 SDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSL-NVNFNTQ
           20        30        40        50        60         70   

              90       100       110       120        130       140
pF1KB6 LGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVDWIYGSTG-VYFSAVKNVIKLS
         :  .:::.: .:. : :...:.: ::   . :::.:::  :.:  .:  ::::. :..
NP_001 KKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVA
            80        90       100       110       120       130   

              150       160       170       180       190       200
pF1KB6 LEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRAS
       . .:. ...::  :.: ...:.::::::::..:.::..: ::::.:::::::::...:  
NP_001 VSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKP
           140       150       160       170       180       190   

              210       220       230       240       250       260
pF1KB6 VEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDH
          :::  :: ::..::.:...:::. :.::.:.. :::. :::::  ...: ... :.:
NP_001 PYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNH
           200       210       220       230       240       250   

              270       280       290       300       310          
pF1KB6 MRAVHLYISALENSCPLMAFPCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQ--GGV---
       .:::::....::..: ...::: ::: . .. :.::      ::::.:   .   ::   
NP_001 QRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKE
           260       270       280       290       300       310   

         320       330       340       350       360       370     
pF1KB6 KIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIP
       ..:  : .. :.: :... :.: ..                                   
NP_001 RMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYE
           320       330       340       350       360       370   




456 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:45:55 2016 done: Sat Nov  5 11:45:56 2016
 Total Scan time:  9.080 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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