Result of FASTA (omim) for pF1KB6677
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6677, 427 aa
  1>>>pF1KB6677 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7986+/-0.00051; mu= 20.3733+/- 0.032
 mean_var=107.4746+/-25.713, 0's: 0 Z-trim(109.5): 539  B-trim: 1986 in 2/53
 Lambda= 0.123715
 statistics sampled from 16979 (17665) to 16979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.207), width:  16
 Scan time:  7.930

The best scores are:                                      opt bits E(85289)
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 2918 532.6 7.5e-151
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 1611 299.3 1.3e-80
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 1611 299.3 1.3e-80
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 1611 299.4 1.4e-80
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 1529 284.7 3.2e-76
NP_001243212 (OMIM: 131243,157300,616367) endothel ( 202) 1427 266.0 6.2e-71
NP_001159527 (OMIM: 131243,157300,616367) endothel ( 318) 1261 236.7 6.7e-62
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384)  606 119.9 1.2e-26
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390)  584 115.9 1.8e-25
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399)  539 107.9 4.7e-23
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613)  491 99.6 2.3e-20
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366)  403 83.6 9.1e-16
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380)  403 83.6 9.3e-16
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  368 77.4 7.6e-14
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415)  354 74.9 4.2e-13
XP_011534148 (OMIM: 162341) PREDICTED: neuromedin- ( 283)  352 74.3 4.3e-13
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389)  347 73.6 9.7e-13
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392)  347 73.6 9.7e-13
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397)  347 73.6 9.8e-13
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400)  347 73.7 9.8e-13
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403)  347 73.7 9.9e-13
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406)  347 73.7 9.9e-13
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414)  347 73.7   1e-12
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418)  347 73.7   1e-12
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420)  347 73.7   1e-12
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446)  347 73.7   1e-12
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493)  347 73.8 1.1e-12
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493)  347 73.8 1.1e-12
XP_016866390 (OMIM: 162341) PREDICTED: neuromedin- ( 301)  339 72.1 2.2e-12
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375)  326 69.9 1.3e-11
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375)  326 69.9 1.3e-11
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  326 69.9 1.3e-11
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  326 69.9 1.3e-11
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  326 69.9 1.3e-11
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  326 69.9 1.3e-11
NP_444264 (OMIM: 607449) neuropeptide FF receptor  ( 420)  325 69.8 1.5e-11
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423)  325 69.8 1.5e-11
XP_016866391 (OMIM: 162341) PREDICTED: neuromedin- ( 242)  322 68.9 1.6e-11
NP_001311237 (OMIM: 162341) neuromedin-B receptor  ( 242)  322 68.9 1.6e-11
NP_001311236 (OMIM: 162341) neuromedin-B receptor  ( 242)  322 68.9 1.6e-11
NP_004876 (OMIM: 607449) neuropeptide FF receptor  ( 522)  325 69.9 1.7e-11
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380)  323 69.3 1.9e-11
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409)  323 69.4 1.9e-11
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321)  310 66.9 8.4e-11
NP_057624 (OMIM: 605569) probable G-protein couple ( 423)  308 66.7 1.3e-10
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  303 65.8 2.4e-10
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292)  297 64.5   4e-10
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300)  297 64.6   4e-10
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300)  297 64.6   4e-10
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300)  297 64.6   4e-10


>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re  (427 aa)
 initn: 2918 init1: 2918 opt: 2918  Z-score: 2829.3  bits: 532.6 E(85289): 7.5e-151
Smith-Waterman score: 2918; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB6 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
              370       380       390       400       410       420

              
pF1KB6 SHKDSMN
       :::::::
NP_001 SHKDSMN
              

>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot  (442 aa)
 initn: 988 init1: 579 opt: 1611  Z-score: 1568.4  bits: 299.3 E(85289): 1.3e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:90-440)

       40        50        60        70        80        90        
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
                                     :    .:  .:::::::.:: .:..:..::
NP_001 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
      60        70        80        90       100       110         

      100       110       120       130       140       150        
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
       .:::::::.::::::::: ::::::::::...:::.::::.::::  :::     :. .:
NP_001 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
     120       130       140       150       160            170    

      160       170       180       190       200       210        
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
       :: ::.::.:::::::.:::::.:::::::::::..:::.:  ::.::: ::..: .::.
NP_001 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
          180       190       200       210       220       230    

      220       230       240         250       260       270      
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
       :::::: .. ..:.:   . :.:. ..:  ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
          240       250       260       270       280       290    

        280       290       300       310       320       330      
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
       ::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. 
NP_001 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
          300        310       320       330       340       350   

        340       350       360       370       380       390      
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
       : ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::     
NP_001 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
           360       370       380       390       400        410  

        400       410       420       
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
       :.  . . ...: .:..  :  :::.: :  
NP_001 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
            420       430        440  

>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel  (442 aa)
 initn: 988 init1: 579 opt: 1611  Z-score: 1568.4  bits: 299.3 E(85289): 1.3e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:90-440)

       40        50        60        70        80        90        
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
                                     :    .:  .:::::::.:: .:..:..::
NP_000 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
      60        70        80        90       100       110         

      100       110       120       130       140       150        
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
       .:::::::.::::::::: ::::::::::...:::.::::.::::  :::     :. .:
NP_000 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
     120       130       140       150       160            170    

      160       170       180       190       200       210        
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
       :: ::.::.:::::::.:::::.:::::::::::..:::.:  ::.::: ::..: .::.
NP_000 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
          180       190       200       210       220       230    

      220       230       240         250       260       270      
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
       :::::: .. ..:.:   . :.:. ..:  ::.::. .::::::.::::.::. ::.:::
NP_000 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
          240       250       260       270       280       290    

        280       290       300       310       320       330      
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
       ::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. 
NP_000 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
          300        310       320       330       340       350   

        340       350       360       370       380       390      
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
       : ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::     
NP_000 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
           360       370       380       390       400        410  

        400       410       420       
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
       :.  . . ...: .:..  :  :::.: :  
NP_000 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
            420       430        440  

>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot  (532 aa)
 initn: 988 init1: 579 opt: 1611  Z-score: 1567.5  bits: 299.4 E(85289): 1.4e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:180-530)

       40        50        60        70        80        90        
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
                                     :    .:  .:::::::.:: .:..:..::
NP_001 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
     150       160       170       180       190       200         

      100       110       120       130       140       150        
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
       .:::::::.::::::::: ::::::::::...:::.::::.::::  :::     :. .:
NP_001 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
     210       220       230       240       250            260    

      160       170       180       190       200       210        
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
       :: ::.::.:::::::.:::::.:::::::::::..:::.:  ::.::: ::..: .::.
NP_001 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
          270       280       290       300       310       320    

      220       230       240         250       260       270      
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
       :::::: .. ..:.:   . :.:. ..:  ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
          330       340       350       360       370       380    

        280       290       300       310       320       330      
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
       ::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. 
NP_001 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
          390        400       410       420       430       440   

        340       350       360       370       380       390      
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
       : ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::     
NP_001 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
           450       460       470       480       490        500  

        400       410       420       
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
       :.  . . ...: .:..  :  :::.: :  
NP_001 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
            510       520        530  

>>NP_003982 (OMIM: 131244,277580,600155,600501) endothel  (436 aa)
 initn: 940 init1: 531 opt: 1529  Z-score: 1489.4  bits: 284.7 E(85289): 3.2e-76
Smith-Waterman score: 1529; 61.8% identity (83.3% similar) in 353 aa overlap (69-415:90-436)

       40        50        60        70        80        90        
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
                                     :    .:  .:::::::.:: .:..:..::
NP_003 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
      60        70        80        90       100       110         

      100       110       120       130       140       150        
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
       .:::::::.::::::::: ::::::::::...:::.::::.::::  :::     :. .:
NP_003 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
     120       130       140       150       160            170    

      160       170       180       190       200       210        
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
       :: ::.::.:::::::.:::::.:::::::::::..:::.:  ::.::: ::..: .::.
NP_003 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
          180       190       200       210       220       230    

      220       230       240         250       260       270      
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
       :::::: .. ..:.:   . :.:. ..:  ::.::. .::::::.::::.::. ::.:::
NP_003 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
          240       250       260       270       280       290    

        280       290       300       310       320       330      
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
       ::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. 
NP_003 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
          300        310       320       330       340       350   

        340       350       360       370       380       390      
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
       : ::::::::::..::::::.:..::::::::::.:::.:::::..           . .
NP_003 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSV
           360       370       380       390       400       410   

        400           410       420       
pF1KB6 SVPMNGTSIQ----WKNHDQNNHNTDRSSHKDSMN
       ..  .::  :    : .. .::.            
NP_003 NIECDGTVNQNPTMWPERKSNNN            
           420       430                  

>>NP_001243212 (OMIM: 131243,157300,616367) endothelin-1  (202 aa)
 initn: 1427 init1: 1427 opt: 1427  Z-score: 1394.5  bits: 266.0 E(85289): 6.2e-71
Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 202 aa overlap (226-427:1-202)

         200       210       220       230       240       250     
pF1KB6 IGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVK
                                     ::::::::::::::::::::::::::::::
NP_001                               MVPFEYRGEQHKTCMLNATSKFMEFYQDVK
                                             10        20        30

         260       270       280       290       300       310     
pF1KB6 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIF
               40        50        60        70        80        90

         320       330       340       350       360       370     
pF1KB6 ALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKK
              100       110       120       130       140       150

         380       390       400       410       420       
pF1KB6 FKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
              160       170       180       190       200  

>>NP_001159527 (OMIM: 131243,157300,616367) endothelin-1  (318 aa)
 initn: 1261 init1: 1261 opt: 1261  Z-score: 1232.3  bits: 236.7 E(85289): 6.7e-62
Smith-Waterman score: 1956; 74.5% identity (74.5% similar) in 427 aa overlap (1-427:1-318)

               10        20        30        40        50        60
pF1KB6 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
       ::::::::::::::::::::                                        
NP_001 SLALGDLIYVVIDLPINVFK----------------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KB6 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              250       260       270       280       290       300
pF1KB6 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
                :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------FYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
                       150       160       170       180       190 

              310       320       330       340       350       360
pF1KB6 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
             200       210       220       230       240       250 

              370       380       390       400       410       420
pF1KB6 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
             260       270       280       290       300       310 

              
pF1KB6 SHKDSMN
       :::::::
NP_001 SHKDSMN
              

>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec  (384 aa)
 initn: 422 init1: 237 opt: 606  Z-score: 599.6  bits: 119.9 E(85289): 1.2e-26
Smith-Waterman score: 606; 33.5% identity (65.2% similar) in 313 aa overlap (81-387:41-340)

               60        70        80        90       100       110
pF1KB6 THQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKC
                                     :.  ..  .:...:..:: ::..:.   : 
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
               20        30        40        50        60        70

              120       130       140       150       160       170
pF1KB6 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG
       ::: :: .:.:::::::. ..   :... . :: ::      :: . :::.::.: .:::
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRW-----LFGRIGCKLIPFIQLTSVG
               80        90       100            110       120     

              180       190       200       210       220          
pF1KB6 ITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPF-
       ..:..: :::.:::.:..    .:.    .   .. . :::.:..::::::.   . :: 
NP_005 VSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFH
         130       140       150       160       170       180     

      230       240       250       260       270       280        
pF1KB6 -EYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNG
        :  ..   .:     :.  :..  ...   :  .. .::   ...: ... ... .   
NP_005 EESTNQTFISCAPYPHSN--ELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLI-QSAY
         190       200         210       220       230        240  

      290       300           310       320       330       340    
pF1KB6 SLRIALSEHLKQ----RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELL
       .: .  . :.:.    :...::::. .: .::.::.: :.  . ..  :.:.: .   .:
NP_005 NLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---ML
            250       260       270       280       290            

          350       360       370       380       390       400    
pF1KB6 SFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTS
        :.  .   .  ::  :::.::.:::..::.:.. :.. : ::                 
NP_005 HFVTSI--CARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTC
     300         310       320       330       340       350       

          410       420           
pF1KB6 IQWKNHDQNNHNTDRSSHKDSMN    
                                  
NP_005 MTSLKSTNPSVATFSLINGNICHERYV
       360       370       380    

>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform  (390 aa)
 initn: 479 init1: 235 opt: 584  Z-score: 578.3  bits: 115.9 E(85289): 1.8e-25
Smith-Waterman score: 584; 30.8% identity (61.0% similar) in 377 aa overlap (49-416:11-371)

       20        30        40        50        60        70        
pF1KB6 ISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSA
                                     :::    .  .: .:  ... : .   :. 
NP_002                     MPSKSLSNLSVTTGANESGSVP-EGWERDFLPASDGTTTE
                                   10        20         30         

       80        90         100       110       120       130      
pF1KB6 FKYINTVISCTIFI--VGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPI
       .    .. :  ..:  ::..::  :..:.  :. ::. :: .:..:: :::. ..  .:.
NP_002 LVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPV
      40        50        60        70        80        90         

        140       150       160       170       180       190      
pF1KB6 NVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGI
       .     :.:. ::.  ::   :::.: .: .:::..:..: :::.:::::...   .:  
NP_002 D-----ASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTS
     100            110       120       130       140       150    

        200       210       220        230       240       250     
pF1KB6 GIPLVTAIEIVSIWILSFILAIPEAI-GFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVK
       :  : : .. ..::..: .::.:::. . :       . .  .:.    .   :..  ..
NP_002 GALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTD--ELHPKIH
          160       170       180       190       200         210  

         260       270       280       290       300           310 
pF1KB6 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ----RREVAKTVFCL
       .  .:  :: .::.  .:.:  .. . : .   .:    .:: :.    :...:: :. .
NP_002 SVLIFLVYFLIPLAIISIYYYHIA-KTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVF
            220       230        240       250       260       270 

             320       330       340       350       360       370 
pF1KB6 VVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYF
       :  : .:::: :.  . ..  :::.: .  ...  :     ..  :.  :::.::.:::.
NP_002 VGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTL-----VARVLSFGNSCVNPFALYL
             280       290       300            310       320      

             380         390       400       410       420         
pF1KB6 VSKKFKNCFQSCLCCC--CYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN  
       .:..:.  :.: :::    :: ..  ::  .......  .  .: .:             
NP_002 LSESFRRHFNSQLCCGRKSYQERG--TSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSM
        330       340       350         360       370       380    

NP_002 KQEMAL
          390

>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [  (399 aa)
 initn: 422 init1: 206 opt: 539  Z-score: 534.8  bits: 107.9 E(85289): 4.7e-23
Smith-Waterman score: 539; 31.6% identity (65.2% similar) in 316 aa overlap (88-387:48-348)

        60        70        80        90              100       110
pF1KB6 VLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFI-------VGMVGNATLLRIIYQNKC
                                     :.:.:       ::..::: :.......: 
NP_001 NDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKS
        20        30        40        50        60        70       

              120       130       140       150       160       170
pF1KB6 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG
       :.. :: .:.:::.:::. ..  .:... . ::  :      :: . ::.. :.. .:::
NP_001 MQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWL-----FGRIGCKVLSFIRLTSVG
        80        90       100       110            120       130  

              180       190       200       210       220       230
pF1KB6 ITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFE
       ..:..:  ::.:::.::..  . :  .  : : ..   .::.:.:.:.::::   .  :.
NP_001 VSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFR
            140       150       160       170       180       190  

                240       250       260       270       280        
pF1KB6 --YRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNG
          ..   ..:    .::  .. :....   :  .. .::   ...:.:..  . .   .
NP_001 DPNKNMTFESCTSYPVSK--KLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYK---S
            200       210         220       230       240          

      290             300       310       320       330        340 
pF1KB6 SLRIALSEH------LKQRREVAKTVFCLVVIFALCWFPLHLSRILKK-TVYNEMDKNRC
       .: :   :.      ...:...:.::. ::..:::::.: ::  . .. :  . .: .  
NP_001 TLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSA-
       250       260       270       280       290       300       

             350       360       370       380       390       400 
pF1KB6 ELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMN
         . :.. .  ..  ::  :::.::.:::..::.:.. :.. : ::              
NP_001 --MHFIFTI--FSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSL
          310         320       330       340       350       360  

             410       420                  
pF1KB6 GTSIQWKNHDQNNHNTDRSSHKDSMN           
                                            
NP_001 TTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
            370       380       390         




427 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:43:22 2016 done: Sat Nov  5 11:43:24 2016
 Total Scan time:  7.930 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com