Result of FASTA (ccds) for pF1KB6691
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6691, 428 aa
  1>>>pF1KB6691 428 - 428 aa - 428 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1431+/-0.000966; mu= 13.5035+/- 0.058
 mean_var=95.3711+/-18.623, 0's: 0 Z-trim(107.0): 56  B-trim: 5 in 1/50
 Lambda= 0.131331
 statistics sampled from 9283 (9325) to 9283 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.286), width:  16
 Scan time:  2.570

The best scores are:                                      opt bits E(32554)
CCDS53486.1 SMYD3 gene_id:64754|Hs108|chr1         ( 428) 2940 567.6 8.4e-162
CCDS31083.1 SMYD3 gene_id:64754|Hs108|chr1         ( 369) 2548 493.2 1.7e-139
CCDS31022.1 SMYD2 gene_id:56950|Hs108|chr1         ( 433)  671 137.6 2.2e-32
CCDS82480.1 SMYD1 gene_id:150572|Hs108|chr2        ( 477)  654 134.5 2.2e-31
CCDS33240.1 SMYD1 gene_id:150572|Hs108|chr2        ( 490)  455 96.8 5.1e-20


>>CCDS53486.1 SMYD3 gene_id:64754|Hs108|chr1              (428 aa)
 initn: 2940 init1: 2940 opt: 2940  Z-score: 3018.3  bits: 567.6 E(32554): 8.4e-162
Smith-Waterman score: 2940; 99.8% identity (100.0% similar) in 428 aa overlap (1-428:1-428)

               10        20        30        40        50        60
pF1KB6 MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLM
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MEPLKVEKFATAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 RCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 RCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 EKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVIC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 NSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 NSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 DMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 DMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHW
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 KWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 KWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 FFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEE
              370       380       390       400       410       420

               
pF1KB6 CDANIRAS
       ::::::::
CCDS53 CDANIRAS
               

>>CCDS31083.1 SMYD3 gene_id:64754|Hs108|chr1              (369 aa)
 initn: 2548 init1: 2548 opt: 2548  Z-score: 2617.8  bits: 493.2 E(32554): 1.7e-139
Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 369 aa overlap (60-428:1-369)

      30        40        50        60        70        80         
pF1KB6 LFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKC
                                     ::::::::::::::::::::::::::::::
CCDS31                               MRCSQCRVAKYCSAKCQKKAWPDHKRECKC
                                             10        20        30

      90       100       110       120       130       140         
pF1KB6 LKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVM
               40        50        60        70        80        90

     150       160       170       180       190       200         
pF1KB6 TFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCD
              100       110       120       130       140       150

     210       220       230       240       250       260         
pF1KB6 PNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQ
              160       170       180       190       200       210

     270       280       290       300       310       320         
pF1KB6 DKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLK
              220       230       240       250       260       270

     330       340       350       360       370       380         
pF1KB6 VLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQA
              280       290       300       310       320       330

     390       400       410       420        
pF1KB6 MKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS
       :::::::::::::::::::::::::::::::::::::::
CCDS31 MKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS
              340       350       360         

>>CCDS31022.1 SMYD2 gene_id:56950|Hs108|chr1              (433 aa)
 initn: 811 init1: 329 opt: 671  Z-score: 694.8  bits: 137.6 E(32554): 2.2e-32
Smith-Waterman score: 822; 32.8% identity (63.4% similar) in 424 aa overlap (6-414:9-426)

                  10        20        30        40        50       
pF1KB6    MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKE
               .:.: . ..: ::::. :.. :.:::     ::..  . ::  :. :.  ::
CCDS31 MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKE
               10        20        30        40        50        60

        60        70        80        90        100       110      
pF1KB6 KLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRY-PPDSVRLLGRVVFKL-MDG
        : .:..:. : ::...:::. :: :: ::. .      . : ..::: .:.. :  .  
CCDS31 GLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHP
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB6 APSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAF
         . :::: .  ..::...:: ..::. ... . ...::. ...     .:   .:   :
CCDS31 ERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLG----FPDNDSLVVLF
              130       140       150       160           170      

         180       190       200       210       220       230     
pF1KB6 AKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEEL
       :.: ::.::: . :....: ...:...:.:::: ::  ....:    .:::..:. :::.
CCDS31 AQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEV
        180       190       200       210       220       230      

         240       250       260       270               280       
pF1KB6 TICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLT----GD----EQVWKEVQ
          :.:.:. .:.:  .:::.: : :.: .: :.:::   .     .:    : .   :.
CCDS31 FTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVR
        240       250       260       270       280       290      

       290         300        310       320       330       340    
pF1KB6 ESLKKIEELK--AHWKWE-QVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLL
        . . :::..   :.:   ..: .:.    . :  . : :.:.:...  :: .:. .   
CCDS31 YARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDW
        300       310       320       330       340       350      

          350       360       370       380       390         400  
pF1KB6 EEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAM--KNLRLAFDIMRV
       : :: :: . ..::   .:      . . .:.:.: .  :.  .:   : :. :. ::.:
CCDS31 EGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYM--GLEHKAAGEKALKKAIAIMEV
        360       370       380       390         400       410    

            410       420        
pF1KB6 THGREHSLIEDLILLLEECDANIRAS
       .::..:  : ..              
CCDS31 AHGKDHPYISEIKQEIESH       
          420       430          

>>CCDS82480.1 SMYD1 gene_id:150572|Hs108|chr2             (477 aa)
 initn: 721 init1: 325 opt: 654  Z-score: 676.8  bits: 134.5 E(32554): 2.2e-31
Smith-Waterman score: 817; 31.5% identity (64.6% similar) in 435 aa overlap (6-426:9-436)

                  10        20        30        40        50       
pF1KB6    MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKE
               :: :.. ..: ::.:.  .  ....:     . .:  .  . ::  :.  .:
CCDS82 MTIGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQE
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB6 KLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAP
       :: ::.::. :.::.  ::: :: .:: ::. .:    . : ...:: .:.....   . 
CCDS82 KLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKR-YGKVPNENIRLAARIMWRVEREGT
               70        80        90        100       110         

       120        130       140       150       160       170      
pF1KB6 SESEK-LYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFA
       . .:  : :  ::....... :.... ::  : :: ..   . :. :.      . . :.
CCDS82 GLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQY----ISHIFG
     120       130       140       150       160           170     

        180        190       200       210       220       230     
pF1KB6 KVICNSFTICNAE-MQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEEL
        . ::.::. . . .: ::::..:...:.::.: :::...::. .. :::.  :  ::::
CCDS82 VINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGKIELRALGKISEGEEL
         180       190       200       210       220       230     

         240       250       260       270              280        
pF1KB6 TICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTG-------DEQVWKEV--
       :. :.:.: .::::..::. :: :.: : .:: . :: :.. :       ...: ::.  
CCDS82 TVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKD-DLFLGVKDNPKPSQEVVKEMIQ
         240       250       260       270        280       290    

          290       300       310       320       330       340    
pF1KB6 --QESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLL
         ...:.::.. ...  ...:. .:.  . ..   . : :::.:..:. . ..   :  .
CCDS82 FSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAF
          300       310       320       330       340       350    

          350        360       370       380       390       400   
pF1KB6 EEALFYGTRTMEPY-RIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVT
       ::: ::. : .. : ... :..  . :. ::..:  . : : .  .   .  :. :. ::
CCDS82 EEASFYARRMVDGYMKLYHPNNAQL-GMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVT
          360       370        380       390       400       410   

           410       420                                           
pF1KB6 HGREHSLIEDLILLLEECDANIRAS                                   
       ::  : . .::  .  . . ..:                                     
CCDS82 HGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALF
           420       430       440       450       460       470   

>>CCDS33240.1 SMYD1 gene_id:150572|Hs108|chr2             (490 aa)
 initn: 710 init1: 241 opt: 455  Z-score: 472.9  bits: 96.8 E(32554): 5.1e-20
Smith-Waterman score: 789; 31.0% identity (62.7% similar) in 448 aa overlap (6-426:9-449)

                  10        20        30        40        50       
pF1KB6    MEPLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKE
               :: :.. ..: ::.:.  .  ....:     . .:  .  . ::  :.  .:
CCDS33 MTIGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQE
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB6 KLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAP
       :: ::.::. :.::.  ::: :: .:: ::. .:    . : ...:: .:.....   . 
CCDS33 KLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKR-YGKVPNENIRLAARIMWRVEREGT
               70        80        90        100       110         

       120        130       140       150       160       170      
pF1KB6 SESEK-LYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFA
       . .:  : :  ::....... :.... ::  : :: ..   . :. :.      . . :.
CCDS33 GLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQY----ISHIFG
     120       130       140       150       160           170     

        180        190       200       210        220              
pF1KB6 KVICNSFTICNAE-MQEVGVGLYPSISLLNHSCDPNCSIVFN-GPH------------LL
        . ::.::. . . .: ::::..:...:.::.: :::...:: : :            . 
CCDS33 VINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIE
         180       190       200       210       220       230     

            230       240       250       260       270            
pF1KB6 LRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTG----
       :::.  :  :::::. :.:.: .::::..::. :: :.: : .:: . :: :.. :    
CCDS33 LRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKD-DLFLGVKDN
         240       250       260       270       280        290    

         280           290       300       310       320       330 
pF1KB6 ---DEQVWKEV----QESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVL
          ...: ::.    ...:.::.. ...  ...:. .:.  . ..   . : :::.:..:
CCDS33 PKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRML
          300       310       320       330       340       350    

             340       350        360       370       380       390
pF1KB6 DCAMDACINLGLLEEALFYGTRTMEPY-RIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAM
       . . ..   :  .::: ::. : .. : ... :..  . :. ::..:  . : : .  . 
CCDS33 SIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQL-GMAVMRAGLTNWHAGNIEVGH
          360       370       380       390        400       410   

              400       410       420                              
pF1KB6 KNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS                      
         .  :. :. ::::  : . .::  .  . . ..:                        
CCDS33 GMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQV
           420       430       440       450       460       470   

CCDS33 MAEPSNEPSPALFHKKQ
           480       490




428 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:23:54 2016 done: Sat Nov  5 11:23:54 2016
 Total Scan time:  2.570 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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