Result of FASTA (omim) for pF1KB6676
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6676, 454 aa
  1>>>pF1KB6676 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.6232+/-0.000375; mu= -1.2949+/- 0.024
 mean_var=254.6483+/-54.375, 0's: 0 Z-trim(120.4): 32  B-trim: 0 in 0/52
 Lambda= 0.080372
 statistics sampled from 35653 (35697) to 35653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.419), width:  16
 Scan time: 10.830

The best scores are:                                      opt bits E(85289)
NP_071354 (OMIM: 614968) SH2 domain-containing pro ( 454) 3021 363.4 7.3e-100
NP_001167630 (OMIM: 614968) SH2 domain-containing  ( 454) 3021 363.4 7.3e-100
NP_001167631 (OMIM: 614968) SH2 domain-containing  ( 409) 2643 319.5 1.1e-86
XP_011542912 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 1708 211.1 4.7e-54
XP_016869218 (OMIM: 614968) PREDICTED: SH2 domain- ( 427) 1708 211.1 4.7e-54
XP_011526692 (OMIM: 608349) PREDICTED: hematopoiet ( 187)  273 44.4 0.00031
XP_016882892 (OMIM: 608349) PREDICTED: hematopoiet ( 218)  273 44.5 0.00034
XP_016882891 (OMIM: 608349) PREDICTED: hematopoiet ( 225)  273 44.5 0.00035
NP_116244 (OMIM: 608349) hematopoietic SH2 domain- ( 352)  273 44.6  0.0005
XP_016882893 (OMIM: 608349) PREDICTED: hematopoiet ( 176)  249 41.6   0.002
XP_011526688 (OMIM: 608349) PREDICTED: hematopoiet ( 405)  249 41.9  0.0038


>>NP_071354 (OMIM: 614968) SH2 domain-containing protein  (454 aa)
 initn: 3021 init1: 3021 opt: 3021  Z-score: 1913.8  bits: 363.4 E(85289): 7.3e-100
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
              370       380       390       400       410       420

              430       440       450    
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
       ::::::::::::::::::::::::::::::::::
NP_071 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
              430       440       450    

>>NP_001167630 (OMIM: 614968) SH2 domain-containing prot  (454 aa)
 initn: 3021 init1: 3021 opt: 3021  Z-score: 1913.8  bits: 363.4 E(85289): 7.3e-100
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
              370       380       390       400       410       420

              430       440       450    
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
       ::::::::::::::::::::::::::::::::::
NP_001 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
              430       440       450    

>>NP_001167631 (OMIM: 614968) SH2 domain-containing prot  (409 aa)
 initn: 2639 init1: 2639 opt: 2643  Z-score: 1677.6  bits: 319.5 E(85289): 1.1e-86
Smith-Waterman score: 2643; 98.5% identity (98.8% similar) in 402 aa overlap (53-454:8-409)

             30        40        50        60        70        80  
pF1KB6 QKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMG
                                     :    :. ::::::::::::::::::::::
NP_001                        MWRVIEPPCPGAPSTENGKSVHWKLGADKEVWVWVMG
                                      10        20        30       

             90       100       110       120       130       140  
pF1KB6 EHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQT
        40        50        60        70        80        90       

            150       160       170       180       190       200  
pF1KB6 KDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKES
       100       110       120       130       140       150       

            210       220       230       240       250       260  
pF1KB6 MKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSL
       160       170       180       190       200       210       

            270       280       290       300       310       320  
pF1KB6 GAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDI
       220       230       240       250       260       270       

            330       340       350       360       370       380  
pF1KB6 IRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYA
       280       290       300       310       320       330       

            390       400       410       420       430       440  
pF1KB6 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQ
       340       350       360       370       380       390       

            450    
pF1KB6 QDQLPDYLELFE
       ::::::::::::
NP_001 QDQLPDYLELFE
       400         

>>XP_011542912 (OMIM: 614968) PREDICTED: SH2 domain-cont  (427 aa)
 initn: 1708 init1: 1708 opt: 1708  Z-score: 1091.4  bits: 211.1 E(85289): 4.7e-54
Smith-Waterman score: 2789; 94.1% identity (94.1% similar) in 454 aa overlap (1-454:1-427)

               10        20        30        40        50        60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_011 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIR---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
                         ::::::::::::::::::::::::::::::::::::::::::
XP_011 ------------------KKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
                               180       190       200       210   

              250       260       270       280       290       300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
           220       230       240       250       260       270   

              310       320       330       340       350       360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
           280       290       300       310       320       330   

              370       380       390       400       410       420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
           340       350       360       370       380       390   

              430       440       450    
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
       ::::::::::::::::::::::::::::::::::
XP_011 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
           400       410       420       

>>XP_016869218 (OMIM: 614968) PREDICTED: SH2 domain-cont  (427 aa)
 initn: 1708 init1: 1708 opt: 1708  Z-score: 1091.4  bits: 211.1 E(85289): 4.7e-54
Smith-Waterman score: 2789; 94.1% identity (94.1% similar) in 454 aa overlap (1-454:1-427)

               10        20        30        40        50        60
pF1KB6 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNI
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 FTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIR---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KB6 QQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------KKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSK
                               180       190       200       210   

              250       260       270       280       290       300
pF1KB6 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAY
           220       230       240       250       260       270   

              310       320       330       340       350       360
pF1KB6 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANEL
           280       290       300       310       320       330   

              370       380       390       400       410       420
pF1KB6 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLV
           340       350       360       370       380       390   

              430       440       450    
pF1KB6 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
       ::::::::::::::::::::::::::::::::::
XP_016 EYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
           400       410       420       

>>XP_011526692 (OMIM: 608349) PREDICTED: hematopoietic S  (187 aa)
 initn: 249 init1: 165 opt: 273  Z-score: 197.1  bits: 44.4 E(85289): 0.00031
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)

          300       310       320       330       340       350    
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
                                     :: . :.      : ..: .  :::: .. 
XP_011               MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
                             10        20             30        40 

          360       370       380       390       400       410    
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
       . :..:: :  . ::::::::.   ::.::: ....: ::..    :.  ..  ... :.
XP_011 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
              50         60        70        80        90       100

          420       430       440        450                       
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE                   
       .:  :: .:...::    .:::  :: :.:    :: .::                    
XP_011 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEER
              110        120       130       140       150         

XP_011 TSQKCSSKSYLLMGLHAPWLPFQSDCEL
     160       170       180       

>>XP_016882892 (OMIM: 608349) PREDICTED: hematopoietic S  (218 aa)
 initn: 249 init1: 165 opt: 273  Z-score: 196.2  bits: 44.5 E(85289): 0.00034
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)

          300       310       320       330       340       350    
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
                                     :: . :.      : ..: .  :::: .. 
XP_016               MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
                             10        20             30        40 

          360       370       380       390       400       410    
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
       . :..:: :  . ::::::::.   ::.::: ....: ::..    :.  ..  ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
              50         60        70        80        90       100

          420       430       440        450                       
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE                   
       .:  :: .:...::    .:::  :: :.:    :: .::                    
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEET
              110        120       130       140       150         

XP_016 ESCFVDQAGVEWHSLGSLQPPPPRFKRFSCLSLLSSWDYRPPQSQSCVTNQRKGSRQQR
     160       170       180       190       200       210        

>>XP_016882891 (OMIM: 608349) PREDICTED: hematopoietic S  (225 aa)
 initn: 249 init1: 165 opt: 273  Z-score: 196.0  bits: 44.5 E(85289): 0.00035
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)

          300       310       320       330       340       350    
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
                                     :: . :.      : ..: .  :::: .. 
XP_016               MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
                             10        20             30        40 

          360       370       380       390       400       410    
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
       . :..:: :  . ::::::::.   ::.::: ....: ::..    :.  ..  ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
              50         60        70        80        90       100

          420       430       440        450                       
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE                   
       .:  :: .:...::    .:::  :: :.:    :: .::                    
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEET
              110        120       130       140       150         

XP_016 ESCFVDQAGVEWHSLGSLQPPPPRFKRFSCLSLLSSWDYRCVLIFVFLVETGFHHVGQTG
     160       170       180       190       200       210         

>>NP_116244 (OMIM: 608349) hematopoietic SH2 domain-cont  (352 aa)
 initn: 249 init1: 165 opt: 273  Z-score: 193.3  bits: 44.6 E(85289): 0.0005
Smith-Waterman score: 273; 36.9% identity (63.1% similar) in 130 aa overlap (325-453:17-139)

          300       310       320       330       340       350    
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
                                     :: . :.      : ..: .  :::: .. 
NP_116               MTEAGKLPLPLPPRLDWFVHTQMG-----QLAQDGVPEWFHGAISR
                             10        20             30        40 

          360       370       380       390       400       410    
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
       . :..:: :  . ::::::::.   ::.::: ....: ::..    :.  ..  ... :.
NP_116 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
              50         60        70        80        90       100

          420       430       440        450                       
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLP-DYLELFE                   
       .:  :: .:...::    .:::  :: :.:    :: .::                    
NP_116 SLDALVTFHQQKPIEPR-RELLTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEA
              110        120       130       140       150         

NP_116 SPKPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQ
     160       170       180       190       200       210         

>>XP_016882893 (OMIM: 608349) PREDICTED: hematopoietic S  (176 aa)
 initn: 238 init1: 165 opt: 249  Z-score: 182.5  bits: 41.6 E(85289): 0.002
Smith-Waterman score: 249; 36.4% identity (63.6% similar) in 121 aa overlap (325-445:17-130)

          300       310       320       330       340       350    
pF1KB6 LNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTL
                                     :: . :.    : : ..: .  :::: .. 
XP_016               MTEAGKLPLPLPPRLDWFVHTQM----G-QLAQDGVPEWFHGAISR
                             10        20             30        40 

          360       370       380       390       400       410    
pF1KB6 KKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHA
       . :..:: :  . ::::::::.   ::.::: ....: ::..    :.  ..  ... :.
XP_016 EDAENLLESQPL-GSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHT
              50         60        70        80        90       100

          420       430       440       450                        
pF1KB6 TLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE                    
       .:  :: .:...::    .:::  :: .  :                             
XP_016 SLDALVTFHQQKPIEPR-RELLTQPCRRIPQTWITRISSSTPTQWPRKLPARCLPLRRPP
              110        120       130       140       150         

XP_016 QSQSCVTNQRKGSRQQR
     160       170      




454 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:21:31 2016 done: Sat Nov  5 11:21:32 2016
 Total Scan time: 10.830 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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