Result of FASTA (omim) for pF1KB6671
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6671, 426 aa
  1>>>pF1KB6671 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8314+/-0.000361; mu= 14.2337+/- 0.023
 mean_var=66.8289+/-13.697, 0's: 0 Z-trim(113.0): 54  B-trim: 0 in 0/54
 Lambda= 0.156889
 statistics sampled from 22056 (22110) to 22056 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.259), width:  16
 Scan time:  7.850

The best scores are:                                      opt bits E(85289)
NP_057272 (OMIM: 612458) actin-like protein 6B [Ho ( 426) 2893 663.8 2.2e-190
NP_004292 (OMIM: 604958) actin-like protein 6A iso ( 429) 2505 576.0 6.2e-164
NP_817126 (OMIM: 604958) actin-like protein 6A iso ( 387) 2236 515.1 1.2e-145
NP_829888 (OMIM: 604958) actin-like protein 6A iso ( 387) 2236 515.1 1.2e-145
NP_001091 (OMIM: 102610,161800,255310,616852) acti ( 377)  460 113.1 1.2e-24
NP_005150 (OMIM: 102540,612098,612794,613424) acti ( 377)  454 111.8 3.1e-24
NP_001092 (OMIM: 102630,243310,607371,608578) acti ( 375)  452 111.3 4.2e-24
NP_001186883 (OMIM: 102560,604717,614583) actin, c ( 375)  451 111.1 4.9e-24
NP_001605 (OMIM: 102560,604717,614583) actin, cyto ( 375)  451 111.1 4.9e-24
NP_001606 (OMIM: 102545) actin, gamma-enteric smoo ( 376)  445 109.7 1.3e-23
NP_001604 (OMIM: 102620,611788,613834,614042) acti ( 377)  439 108.4 3.2e-23
NP_001307784 (OMIM: 102620,611788,613834,614042) a ( 377)  439 108.4 3.2e-23
NP_001135417 (OMIM: 102620,611788,613834,614042) a ( 377)  439 108.4 3.2e-23
NP_001017992 (OMIM: 614835) beta-actin-like protei ( 376)  431 106.6 1.1e-22
NP_005726 (OMIM: 605144) beta-centractin [Homo sap ( 376)  416 103.2 1.2e-21
NP_005727 (OMIM: 605143) alpha-centractin [Homo sa ( 376)  410 101.8   3e-21
XP_016859649 (OMIM: 608914) PREDICTED: POTE ankyri ( 657)  413 102.6 3.2e-21
XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957)  413 102.6 4.5e-21
XP_016859648 (OMIM: 608914) PREDICTED: POTE ankyri ( 967)  413 102.6 4.5e-21
XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075)  413 102.6   5e-21
NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075)  413 102.6   5e-21
NP_005712 (OMIM: 604222) actin-related protein 3 i ( 418)  403 100.3   1e-20
NP_001264069 (OMIM: 604222) actin-related protein  ( 367)  364 91.4 4.1e-18
XP_016858605 (OMIM: 605144) PREDICTED: beta-centra ( 332)  351 88.5 2.8e-17
NP_006677 (OMIM: 604304) actin-like protein 7B [Ho ( 415)  349 88.0 4.8e-17
NP_536356 (OMIM: 608535) actin-related protein T2  ( 377)  345 87.1 8.2e-17
XP_005263911 (OMIM: 605144) PREDICTED: beta-centra ( 302)  341 86.2 1.3e-16
NP_001186822 (OMIM: 102545) actin, gamma-enteric s ( 333)  320 81.4 3.7e-15
NP_115876 (OMIM: 608534) actin-related protein T3  ( 372)  313 79.9 1.2e-14
NP_001005386 (OMIM: 604221) actin-related protein  ( 399)  310 79.2 2.1e-14
NP_006678 (OMIM: 604303) actin-like protein 7A [Ho ( 435)  308 78.8 3.1e-14
NP_612146 (OMIM: 300487) actin-related protein T1  ( 376)  301 77.2 8.1e-14
NP_005713 (OMIM: 604221) actin-related protein 2 i ( 394)  295 75.8 2.2e-13


>>NP_057272 (OMIM: 612458) actin-like protein 6B [Homo s  (426 aa)
 initn: 2893 init1: 2893 opt: 2893  Z-score: 3538.8  bits: 663.8 E(85289): 2.2e-190
Smith-Waterman score: 2893; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
              370       380       390       400       410       420

             
pF1KB6 VERKCP
       ::::::
NP_057 VERKCP
             

>>NP_004292 (OMIM: 604958) actin-like protein 6A isoform  (429 aa)
 initn: 2493 init1: 2209 opt: 2505  Z-score: 3064.1  bits: 576.0 E(85289): 6.2e-164
Smith-Waterman score: 2505; 83.9% identity (95.6% similar) in 429 aa overlap (1-426:1-429)

               10        20        30        40        50          
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGG--LELEGDK
       ::::::::::::::::::::..::::::::::::.::::..:... .. :.  .:..:::
NP_004 MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDK
               10        20        30        40        50        60

       60         70        80        90       100       110       
pF1KB6 EKKG-KIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPV
        :.:   ..::::::.:::.. :..:::::::.:::. :.:::::::. ::::: .::::
NP_004 GKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPV
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB6 LMSEAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAI
       ::::::::::::::::::::::.:::::::::::::::::::::::::.:::::::::::
NP_004 LMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAI
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB6 PVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKK
       ::::::::::::::::::::::.:::::::::: :...::::::.:: ::::.: :::.:
NP_004 PVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRK
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB6 EKLPQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAE
       ::::::..:::::::: ::::::::::::::: :::::::::::::::.::::: :.:::
NP_004 EKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAE
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB6 RLRIPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGF
       ::.::::::::::::::::::::::.::::::.:::::::::::::::::.:::::.:.:
NP_004 RLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSF
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB6 TDRLNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGG
       ::::::::::::::::::::::.:.:.::.:: :::::::::::::::::::::::::::
NP_004 TDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGG
              370       380       390       400       410       420

       420      
pF1KB6 KQCVERKCP
       :::::::::
NP_004 KQCVERKCP
                

>>NP_817126 (OMIM: 604958) actin-like protein 6A isoform  (387 aa)
 initn: 2209 init1: 2209 opt: 2236  Z-score: 2735.8  bits: 515.1 E(85289): 1.2e-145
Smith-Waterman score: 2236; 85.6% identity (96.0% similar) in 376 aa overlap (52-426:12-387)

              30        40        50        60         70        80
pF1KB6 SVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEKKG-KIFHIDTNALHVPRDGAE
                                     .:..::: :.:   ..::::::.:::.. :
NP_817                    MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENME
                                  10        20        30        40 

               90       100       110       120       130       140
pF1KB6 VMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTRAKREKLTELMFEQ
       ..:::::::.:::. :.:::::::. ::::: .::::::::::::::::::::::::::.
NP_817 AISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEH
              50        60        70        80        90       100 

              150       160       170       180       190       200
pF1KB6 YNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIS
       :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::.
NP_817 YNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIT
             110       120       130       140       150       160 

              210       220       230       240       250       260
pF1KB6 MQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQ
       :::::::::: :...::::::.:: ::::.: :::.:::::::..:::::::: ::::::
NP_817 MQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQ
             170       180       190       200       210       220 

              270       280       290       300       310       320
pF1KB6 ASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFDPSNVKGLSGNTML
       ::::::::: :::::::::::::::.::::: :.:::::.::::::::::::::::::::
NP_817 ASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTML
             230       240       250       260       270       280 

              330       340       350       360       370       380
pF1KB6 GVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIAS
       ::.::::::.:::::::::::::::::.:::::.:.:::::::::::::::::::::::.
NP_817 GVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIAN
             290       300       310       320       330       340 

              390       400       410       420      
pF1KB6 NSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP
       :.:.::.:: ::::::::::::::::::::::::::::::::::::
NP_817 NTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP
             350       360       370       380       

>>NP_829888 (OMIM: 604958) actin-like protein 6A isoform  (387 aa)
 initn: 2209 init1: 2209 opt: 2236  Z-score: 2735.8  bits: 515.1 E(85289): 1.2e-145
Smith-Waterman score: 2236; 85.6% identity (96.0% similar) in 376 aa overlap (52-426:12-387)

              30        40        50        60         70        80
pF1KB6 SVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEKKG-KIFHIDTNALHVPRDGAE
                                     .:..::: :.:   ..::::::.:::.. :
NP_829                    MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENME
                                  10        20        30        40 

               90       100       110       120       130       140
pF1KB6 VMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTRAKREKLTELMFEQ
       ..:::::::.:::. :.:::::::. ::::: .::::::::::::::::::::::::::.
NP_829 AISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEH
              50        60        70        80        90       100 

              150       160       170       180       190       200
pF1KB6 YNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIS
       :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::.
NP_829 YNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFIT
             110       120       130       140       150       160 

              210       220       230       240       250       260
pF1KB6 MQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKLPQVSKSWHNYMCNEVIQDFQ
       :::::::::: :...::::::.:: ::::.: :::.:::::::..:::::::: ::::::
NP_829 MQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQ
             170       180       190       200       210       220 

              270       280       290       300       310       320
pF1KB6 ASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLRIPEGLFDPSNVKGLSGNTML
       ::::::::: :::::::::::::::.::::: :.:::::.::::::::::::::::::::
NP_829 ASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTML
             230       240       250       260       270       280 

              330       340       350       360       370       380
pF1KB6 GVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQKTPPSMRLKLIAS
       ::.::::::.:::::::::::::::::.:::::.:.:::::::::::::::::::::::.
NP_829 GVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIAN
             290       300       310       320       330       340 

              390       400       410       420      
pF1KB6 NSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP
       :.:.::.:: ::::::::::::::::::::::::::::::::::::
NP_829 NTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP
             350       360       370       380       

>>NP_001091 (OMIM: 102610,161800,255310,616852) actin, a  (377 aa)
 initn: 881 init1: 319 opt: 460  Z-score: 563.5  bits: 113.1 E(85289): 1.2e-24
Smith-Waterman score: 872; 37.6% identity (64.3% similar) in 417 aa overlap (9-425:5-376)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               ::. ::: : ::  :.::.::.: :.: ::. ::    .. : .   :.:..
NP_001     MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                   10        20        30          40        50    

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.: .:. .. :  ::. ....  :. ::.:..
NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLT
                60         70        80        90       100        

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .:.::...   :::. .:.::.::.:::::   :  .:..
NP_001 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY
      110       120       130       140       150       160        

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ...     : .: ::.        ::::
NP_001 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL
      170       180       190       200          210               

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_001 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                 220        230       240               250        

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        :: ::.:: .    :    :. ... .::  ::::::  ::.. ...::.:.  :..::
NP_001 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADR
      260           270       280       290       300       310    

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.:::::::.::::.:.: . 
NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSI
          320       330          340       350       360       370 

             
pF1KB6 VERKCP
       :.::: 
NP_001 VHRKCF
             

>>NP_005150 (OMIM: 102540,612098,612794,613424) actin, a  (377 aa)
 initn: 878 init1: 319 opt: 454  Z-score: 556.2  bits: 111.8 E(85289): 3.1e-24
Smith-Waterman score: 869; 37.6% identity (64.3% similar) in 417 aa overlap (9-425:5-376)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               .:. ::: : ::  :.::.::.: :.: ::. ::    .. : .   :.:..
NP_005     MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                   10        20        30          40        50    

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.: .:. .. :  ::. ....  :. ::.:..
NP_005 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLT
                60         70        80        90       100        

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .:.::...   :::. .:.::.::.:::::   :  .:..
NP_005 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY
      110       120       130       140       150       160        

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ...     : .: ::.        ::::
NP_005 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL
      170       180       190       200          210               

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_005 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                 220        230       240               250        

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        :: ::.:: .    :    :. ... .::  ::::::  ::.. ...::.:.  :..::
NP_005 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADR
      260           270       280       290       300       310    

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.::::::::::::.:.: . 
NP_005 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSI
          320       330          340       350       360       370 

             
pF1KB6 VERKCP
       :.::: 
NP_005 VHRKCF
             

>>NP_001092 (OMIM: 102630,243310,607371,608578) actin, c  (375 aa)
 initn: 885 init1: 318 opt: 452  Z-score: 553.7  bits: 111.3 E(85289): 4.2e-24
Smith-Waterman score: 868; 36.9% identity (64.5% similar) in 417 aa overlap (9-425:3-374)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               :...::: : ::   .::.::.: :.: ::. ::    .. : .   :.:..
NP_001       MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                     10        20        30          40        50  

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.. .:. .. :  ::. ....  :. ::::..
NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT
                   60        70        80        90       100      

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .: ::...   :::. .:.::.::.:.:::   : ..:..
NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ..      : .: ::.        ::::
NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL
        170       180       190       200          210             

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                    220       230               240       250      

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        ::.::.::    . :    :. ... .::  ::.:::  ::......::.:.  :..::
NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR
        260           270       280       290       300       310  

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.::::::::::::.:.: . 
NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI
            320       330          340       350       360         

             
pF1KB6 VERKCP
       :.::: 
NP_001 VHRKCF
     370     

>>NP_001186883 (OMIM: 102560,604717,614583) actin, cytop  (375 aa)
 initn: 884 init1: 318 opt: 451  Z-score: 552.5  bits: 111.1 E(85289): 4.9e-24
Smith-Waterman score: 867; 36.9% identity (64.7% similar) in 417 aa overlap (9-425:3-374)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               .:..:::.: ::   .::.::.: :.: ::. ::    .. : .   :.:..
NP_001       MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                     10        20        30          40        50  

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.. .:. .. :  ::. ....  :. ::::..
NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT
                   60        70        80        90       100      

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .: ::...   :::. .:.::.::.:.:::   : ..:..
NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ..      : .: ::.        ::::
NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL
        170       180       190       200          210             

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                    220       230               240       250      

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        ::.::.::    . :    :. ... .::  ::.:::  ::......::.:.  :..::
NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR
        260           270       280       290       300       310  

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.::::::::::::.:.: . 
NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI
            320       330          340       350       360         

             
pF1KB6 VERKCP
       :.::: 
NP_001 VHRKCF
     370     

>>NP_001605 (OMIM: 102560,604717,614583) actin, cytoplas  (375 aa)
 initn: 884 init1: 318 opt: 451  Z-score: 552.5  bits: 111.1 E(85289): 4.9e-24
Smith-Waterman score: 867; 36.9% identity (64.7% similar) in 417 aa overlap (9-425:3-374)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               .:..:::.: ::   .::.::.: :.: ::. ::    .. : .   :.:..
NP_001       MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                     10        20        30          40        50  

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.. .:. .. :  ::. ....  :. ::::..
NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT
                   60        70        80        90       100      

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .: ::...   :::. .:.::.::.:.:::   : ..:..
NP_001 EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIY
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ..      : .: ::.        ::::
NP_001 EGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT---TAEREIVRD-------IKEKL
        170       180       190       200          210             

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_001 -----------CY-VALDFEQEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                    220       230               240       250      

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        ::.::.::    . :    :. ... .::  ::.:::  ::......::.:.  :..::
NP_001 CPEALFQPS----FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADR
        260           270       280       290       300       310  

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.::::::::::::.:.: . 
NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSI
            320       330          340       350       360         

             
pF1KB6 VERKCP
       :.::: 
NP_001 VHRKCF
     370     

>>NP_001606 (OMIM: 102545) actin, gamma-enteric smooth m  (376 aa)
 initn: 861 init1: 316 opt: 445  Z-score: 545.2  bits: 109.7 E(85289): 1.3e-23
Smith-Waterman score: 852; 36.9% identity (63.8% similar) in 417 aa overlap (9-425:4-375)

               10        20        30        40        50        60
pF1KB6 MSGGVYGGDEVGALVFDIGSFSVRAGYAGEDCPKADFPTTVGLLAAEEGGGLELEGDKEK
               .:. ::: : ::   .::.::.: :.: ::. ::    .. : .   :.:..
NP_001      MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVG--RPRHQGVMVGMGQKDS
                    10        20        30          40        50   

               70        80        90       100       110       120
pF1KB6 KGKIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHTYSKHVKSEPNLHPVLMS
            ..  .: .  :    .  :...:.: .:. .. :  :.. ....  :. ::.:..
NP_001 -----YVGDEA-QSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLT
                  60        70        80        90       100       

              130       140       150       160       170       180
pF1KB6 EAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVH
       ::: : .:.:::.:..::: .:.::...   :::. .:.::.::.:::::   :  .:..
NP_001 EAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIY
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KB6 DGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPNWKKKEKL
       .::.: ..:..  :::  ..    ... : . ...     : .: ::.        ::::
NP_001 EGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVT---TAEREIVRD-------IKEKL
       170       180       190       200          210              

              250       260       270       280       290       300
pF1KB6 PQVSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAERLR
                  :  :  ::.  .  ...:   :.         ::.:.:     : ::.:
NP_001 -----------CY-VALDFENEMATAASSSSLEK--------SYELPDGQVITIGNERFR
                   220       230               240       250       

              310       320       330       340       350       360
pF1KB6 IPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDR
        :: ::.:: .    :    :. ... .::  ::::::  ::.. ...::.:.  :..::
NP_001 CPETLFQPSFI----GMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADR
       260           270       280       290       300       310   

              370       380       390       400       410       420
pF1KB6 LNRELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQC
       ...:..  .: .:..:.::     :::.: ::::::::::.::::::::: ::.:.: . 
NP_001 MQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSI
           320       330          340       350       360       370

             
pF1KB6 VERKCP
       :.::: 
NP_001 VHRKCF
             




426 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:19:40 2016 done: Sat Nov  5 11:19:41 2016
 Total Scan time:  7.850 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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