Result of FASTA (omim) for pF1KB5982
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5982, 568 aa
  1>>>pF1KB5982 568 - 568 aa - 568 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7071+/-0.000439; mu= 16.6954+/- 0.027
 mean_var=83.5379+/-18.115, 0's: 0 Z-trim(109.7): 418  B-trim: 0 in 0/51
 Lambda= 0.140324
 statistics sampled from 17412 (17868) to 17412 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.561), E-opt: 0.2 (0.209), width:  16
 Scan time:  9.590

The best scores are:                                      opt bits E(85289)
NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 3809 781.8       0
NP_001289980 (OMIM: 614522) kelch-like protein 12  ( 606) 3809 781.8       0
XP_011508137 (OMIM: 614522) PREDICTED: kelch-like  ( 623) 3809 781.8       0
XP_016857484 (OMIM: 614522) PREDICTED: kelch-like  ( 471) 3113 640.8 2.8e-183
XP_011508138 (OMIM: 614522) PREDICTED: kelch-like  ( 526) 3113 640.9 3.1e-183
NP_001290038 (OMIM: 614522) kelch-like protein 12  ( 467) 2284 473.0 9.2e-133
XP_011508139 (OMIM: 614522) PREDICTED: kelch-like  ( 522) 2284 473.0  1e-132
NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 1505 315.4 3.3e-85
NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 1499 314.1 7.3e-85
NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 1490 312.3 2.7e-84
NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 1490 312.3 2.7e-84
XP_016863163 (OMIM: 605774) PREDICTED: kelch-like  ( 555) 1481 310.5 9.2e-84
XP_011529874 (OMIM: 605774) PREDICTED: kelch-like  ( 633) 1452 304.7   6e-82
NP_001165125 (OMIM: 608064) kelch-like protein 5 i ( 568) 1431 300.4   1e-80
NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709) 1431 300.4 1.2e-80
NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755) 1431 300.5 1.3e-80
XP_016863764 (OMIM: 608064) PREDICTED: kelch-like  ( 788) 1431 300.5 1.4e-80
XP_005262712 (OMIM: 608064) PREDICTED: kelch-like  ( 789) 1431 300.5 1.4e-80
XP_016863763 (OMIM: 608064) PREDICTED: kelch-like  ( 804) 1411 296.4 2.3e-79
XP_016863762 (OMIM: 608064) PREDICTED: kelch-like  ( 804) 1411 296.4 2.3e-79
XP_011512001 (OMIM: 608064) PREDICTED: kelch-like  ( 804) 1411 296.4 2.3e-79
XP_011512003 (OMIM: 608064) PREDICTED: kelch-like  ( 788) 1408 295.8 3.4e-79
XP_011512002 (OMIM: 608064) PREDICTED: kelch-like  ( 788) 1408 295.8 3.4e-79
XP_016863765 (OMIM: 608064) PREDICTED: kelch-like  ( 788) 1408 295.8 3.4e-79
XP_016876167 (OMIM: 605332) PREDICTED: kelch-like  ( 575) 1406 295.3 3.5e-79
NP_065917 (OMIM: 605332) kelch-like protein 1 isof ( 748) 1406 295.4 4.3e-79
NP_001278932 (OMIM: 611967) kelch-like protein 8 i ( 620) 1400 294.1 8.6e-79
NP_065854 (OMIM: 611967) kelch-like protein 8 isof ( 620) 1400 294.1 8.6e-79
NP_061990 (OMIM: 300348) kelch-like protein 4 isof ( 718) 1367 287.5   1e-76
NP_950240 (OMIM: 608064) kelch-like protein 5 isof ( 694) 1359 285.9   3e-76
NP_476503 (OMIM: 300348) kelch-like protein 4 isof ( 720) 1350 284.0 1.1e-75
NP_001273654 (OMIM: 605332) kelch-like protein 1 i ( 687) 1328 279.6 2.3e-74
NP_001244124 (OMIM: 605775,614495) kelch-like prot ( 505) 1323 278.5 3.6e-74
XP_016876168 (OMIM: 605332) PREDICTED: kelch-like  ( 525) 1319 277.7 6.5e-74
NP_001154994 (OMIM: 605774) kelch-like protein 2 i ( 505) 1299 273.6   1e-72
XP_016863165 (OMIM: 605774) PREDICTED: kelch-like  ( 505) 1299 273.6   1e-72
NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624) 1247 263.2 1.8e-69
XP_005260230 (OMIM: 606016) PREDICTED: kelch-like  ( 624) 1247 263.2 1.8e-69
XP_011526754 (OMIM: 606016) PREDICTED: kelch-like  ( 624) 1247 263.2 1.8e-69
NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624) 1247 263.2 1.8e-69
XP_005260231 (OMIM: 606016) PREDICTED: kelch-like  ( 624) 1247 263.2 1.8e-69
NP_001317953 (OMIM: 605774) kelch-like protein 2 i ( 496) 1227 259.0 2.5e-68
XP_011529878 (OMIM: 605774) PREDICTED: kelch-like  ( 496) 1227 259.0 2.5e-68
NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608) 1219 257.5 9.1e-68
NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608) 1219 257.5 9.1e-68
NP_001278935 (OMIM: 611967) kelch-like protein 8 i ( 544) 1165 246.5 1.6e-64
XP_016863164 (OMIM: 605774) PREDICTED: kelch-like  ( 415) 1099 233.1 1.4e-60
NP_001316525 (OMIM: 608778,615081) kelch-like prot ( 520) 1071 227.5 8.4e-59
NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 1030 219.2 2.9e-56
XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 1016 216.4   2e-55


>>NP_067646 (OMIM: 614522) kelch-like protein 12 isoform  (568 aa)
 initn: 3809 init1: 3809 opt: 3809  Z-score: 4171.8  bits: 781.8 E(85289):    0
Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:1-568)

               10        20        30        40        50        60
pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY
              490       500       510       520       530       540

              550       560        
pF1KB5 DPIIDSWEVVTSMGTQRCDAGVCVLREK
       ::::::::::::::::::::::::::::
NP_067 DPIIDSWEVVTSMGTQRCDAGVCVLREK
              550       560        

>>NP_001289980 (OMIM: 614522) kelch-like protein 12 isof  (606 aa)
 initn: 3809 init1: 3809 opt: 3809  Z-score: 4171.4  bits: 781.8 E(85289):    0
Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:39-606)

                                             10        20        30
pF1KB5                               MGGIMAPKDIMTNTHAKSILNSMNSLRKSN
                                     ::::::::::::::::::::::::::::::
NP_001 SVGFLDVKKFLSTWKLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN
       10        20        30        40        50        60        

               40        50        60        70        80        90
pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
       70        80        90       100       110       120        

              100       110       120       130       140       150
pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
      130       140       150       160       170       180        

              160       170       180       190       200       210
pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
      190       200       210       220       230       240        

              220       230       240       250       260       270
pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
      250       260       270       280       290       300        

              280       290       300       310       320       330
pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
      310       320       330       340       350       360        

              340       350       360       370       380       390
pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
      370       380       390       400       410       420        

              400       410       420       430       440       450
pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
      430       440       450       460       470       480        

              460       470       480       490       500       510
pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
      490       500       510       520       530       540        

              520       530       540       550       560        
pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
      550       560       570       580       590       600      

>>XP_011508137 (OMIM: 614522) PREDICTED: kelch-like prot  (623 aa)
 initn: 3809 init1: 3809 opt: 3809  Z-score: 4171.2  bits: 781.8 E(85289):    0
Smith-Waterman score: 3809; 100.0% identity (100.0% similar) in 568 aa overlap (1-568:56-623)

                                             10        20        30
pF1KB5                               MGGIMAPKDIMTNTHAKSILNSMNSLRKSN
                                     ::::::::::::::::::::::::::::::
XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
          90       100       110       120       130       140     

              100       110       120       130       140       150
pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
         150       160       170       180       190       200     

              160       170       180       190       200       210
pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
         210       220       230       240       250       260     

              220       230       240       250       260       270
pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
         270       280       290       300       310       320     

              280       290       300       310       320       330
pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
         330       340       350       360       370       380     

              340       350       360       370       380       390
pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
         390       400       410       420       430       440     

              400       410       420       430       440       450
pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
         450       460       470       480       490       500     

              460       470       480       490       500       510
pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
         510       520       530       540       550       560     

              520       530       540       550       560        
pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
         570       580       590       600       610       620   

>>XP_016857484 (OMIM: 614522) PREDICTED: kelch-like prot  (471 aa)
 initn: 3390 init1: 3113 opt: 3113  Z-score: 3411.4  bits: 640.8 E(85289): 2.8e-183
Smith-Waterman score: 3113; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)

               10        20        30        40        50        60
pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSDMMVIPC         
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY

>>XP_011508138 (OMIM: 614522) PREDICTED: kelch-like prot  (526 aa)
 initn: 3390 init1: 3113 opt: 3113  Z-score: 3410.7  bits: 640.9 E(85289): 3.1e-183
Smith-Waterman score: 3113; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:56-519)

                                             10        20        30
pF1KB5                               MGGIMAPKDIMTNTHAKSILNSMNSLRKSN
                                     ::::::::::::::::::::::::::::::
XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
          90       100       110       120       130       140     

              100       110       120       130       140       150
pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
         150       160       170       180       190       200     

              160       170       180       190       200       210
pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
         210       220       230       240       250       260     

              220       230       240       250       260       270
pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
         270       280       290       300       310       320     

              280       290       300       310       320       330
pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
         330       340       350       360       370       380     

              340       350       360       370       380       390
pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
         390       400       410       420       430       440     

              400       410       420       430       440       450
pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
         450       460       470       480       490       500     

              460       470       480       490       500       510
pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
       ::::::::::::::                                              
XP_011 GHWTNVTPMATKRSDMMVIPC                                       
         510       520                                             

>>NP_001290038 (OMIM: 614522) kelch-like protein 12 isof  (467 aa)
 initn: 3123 init1: 1844 opt: 2284  Z-score: 2504.5  bits: 473.0 E(85289): 9.2e-133
Smith-Waterman score: 2925; 82.2% identity (82.2% similar) in 568 aa overlap (1-568:1-467)

               10        20        30        40        50        60
pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVE
       :::::::::::::::::::::::::::::::::::::                       
NP_001 FIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARL-----------------------
              250       260       270                              

              310       320       330       340       350       360
pF1KB5 KYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWY
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              370       380       390       400       410       420
pF1KB5 SVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------DMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAG
                         280       290       300       310         

              430       440       450       460       470       480
pF1KB5 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGG
     320       330       340       350       360       370         

              490       500       510       520       530       540
pF1KB5 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECY
     380       390       400       410       420       430         

              550       560        
pF1KB5 DPIIDSWEVVTSMGTQRCDAGVCVLREK
       ::::::::::::::::::::::::::::
NP_001 DPIIDSWEVVTSMGTQRCDAGVCVLREK
     440       450       460       

>>XP_011508139 (OMIM: 614522) PREDICTED: kelch-like prot  (522 aa)
 initn: 3123 init1: 1844 opt: 2284  Z-score: 2503.8  bits: 473.0 E(85289): 1e-132
Smith-Waterman score: 2925; 82.2% identity (82.2% similar) in 568 aa overlap (1-568:56-522)

                                             10        20        30
pF1KB5                               MGGIMAPKDIMTNTHAKSILNSMNSLRKSN
                                     ::::::::::::::::::::::::::::::
XP_011 GFAVIPRRVWNSGAQLQNPRTHFVLSPHCFMGGIMAPKDIMTNTHAKSILNSMNSLRKSN
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KB5 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDF
          90       100       110       120       130       140     

              100       110       120       130       140       150
pF1KB5 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDL
         150       160       170       180       190       200     

              160       170       180       190       200       210
pF1KB5 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKE
         210       220       230       240       250       260     

              220       230       240       250       260       270
pF1KB5 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQG
         270       280       290       300       310       320     

              280       290       300       310       320       330
pF1KB5 PRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDR
       :::::::                                                     
XP_011 PRTRARL-----------------------------------------------------
         330                                                       

              340       350       360       370       380       390
pF1KB5 IYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGS
                                                       ::::::::::::
XP_011 ------------------------------------------------DMIYVSGGFDGS
                                                            340    

              400       410       420       430       440       450
pF1KB5 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHT
          350       360       370       380       390       400    

              460       470       480       490       500       510
pF1KB5 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPR
          410       420       430       440       450       460    

              520       530       540       550       560        
pF1KB5 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
          470       480       490       500       510       520  

>>NP_059111 (OMIM: 605775,614495) kelch-like protein 3 i  (587 aa)
 initn: 1276 init1: 899 opt: 1505  Z-score: 1650.7  bits: 315.4 E(85289): 3.3e-85
Smith-Waterman score: 1505; 41.1% identity (72.8% similar) in 569 aa overlap (8-567:24-585)

                               10         20        30        40   
pF1KB5                 MGGIMAPKDIMTN-THAKSILNSMNSLRKSNTLCDVTLRVEQKD
                              . : .: .:  . .. :: ::... :::: . .:. .
NP_059 MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVE
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB5 FPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENV
       . :::.:::::: :::::::...::.    ..:. . ..:.  :.:..::  ..:: :::
NP_059 IEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB5 QELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP
       : ::::: ::::  :.: ::.::.::: :.:::::: ::..:.:.::.: :......:::
NP_059 QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KB5 EVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVR
       ::.  :::. ::  .: .::. :.. :.::: ::::::.:... :. : : . .:...::
NP_059 EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR
              190       200       210       220       230       240

           230       240       250       260        270       280  
pF1KB5 MPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN--
       .:::   :...... : .:. .  :.:.. :: :.:: : . :  ...:::. :  ..  
NP_059 LPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLP
              250       260       270       280       290       300

              290         300       310       320       330        
pF1KB5 EVLLVVGGFGSQQSP--IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYD
       .:..::::    :.:  :  :: :: . ..:. .  .  .:  .. : .  ..:..::..
NP_059 KVMIVVGG----QAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFN
                  310       320       330       340       350      

      340       350       360       370       380       390        
pF1KB5 GRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMER
       :  :. .:.  : . :.   : :.: :. ::.  ::..:.:..:. ::::::   .:.: 
NP_059 GSLRVRTVDVYDGVKDQ---WTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEA
        360       370          380       390       400       410   

      400       410       420       430         440       450      
pF1KB5 YDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNV
       :. . ..: ... :.: : ..:. :. : .: .::::: .   :..::.:.: :..:  :
NP_059 YSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYV
           420       430       440       450       460       470   

        460       470       480       490       500       510      
pF1KB5 TPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGAT
       . :.:.::::::..:. ..:..:: ::    .:::.:.  :..:  :..:.  :  .:. 
NP_059 ADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVC
           480       490       500       510       520       530   

        520       530       540       550        560         
pF1KB5 VLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVV-TSMGTQRCDAGVCVLREK 
       .. : ::...: ::.  :.:.: :.:. :.: .. :.:.: :  ::: :...  
NP_059 AVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL
           540       550       560       570       580       

>>NP_001244123 (OMIM: 605775,614495) kelch-like protein   (555 aa)
 initn: 1276 init1: 899 opt: 1499  Z-score: 1644.5  bits: 314.1 E(85289): 7.3e-85
Smith-Waterman score: 1499; 41.8% identity (73.2% similar) in 553 aa overlap (23-567:8-553)

               10        20        30        40        50        60
pF1KB5 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCA
                             :: ::... :::: . .:. .. :::.:::::: ::::
NP_001                MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCA
                              10        20        30        40     

               70        80        90       100       110       120
pF1KB5 MFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQ
       :::...::.    ..:. . ..:.  :.:..::  ..:: :::: ::::: ::::  :.:
NP_001 MFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQ
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KB5 ACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVE
        ::.::.::: :.:::::: ::..:.:.::.: :......:::::.  :::. ::  .: 
NP_001 NCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVC
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KB5 KLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEP
       .::. :.. :.::: ::::::.:... :. : : . .:...::.:::   :...... : 
NP_001 SLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEA
         170       180       190       200       210       220     

              250       260        270       280         290       
pF1KB5 FIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN--EVLLVVGGFGSQQSP--
       .:. .  :.:.. :: :.:: : . :  ...:::. :  ..  .:..::::    :.:  
NP_001 LIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGG----QAPKA
         230       240       250       260       270           280 

         300       310       320       330       340       350     
pF1KB5 IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADE
       :  :: :: . ..:. .  .  .:  .. : .  ..:..::..:  :. .:.  : . :.
NP_001 IRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQ
             290       300       310       320       330       340 

         360       370       380       390       400       410     
pF1KB5 DGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTA
          : :.: :. ::.  ::..:.:..:. ::::::   .:.: :. . ..: ... :.: 
NP_001 ---WTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTR
                350       360       370       380       390        

         420       430         440       450       460       470   
pF1KB5 REGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLND
       : ..:. :. : .: .::::: .   :..::.:.: :..:  :. :.:.::::::..:. 
NP_001 RSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSG
      400       410       420       430       440       450        

           480       490       500       510       520       530   
pF1KB5 HIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSL
       ..:..:: ::    .:::.:.  :..:  :..:.  :  .:. .. : ::...: ::.  
NP_001 QLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCN
      460       470       480       490       500       510        

           540       550        560         
pF1KB5 LSSIECYDPIIDSWEVV-TSMGTQRCDAGVCVLREK 
       :.:.: :.:. :.: .. :.:.: :  ::: :...  
NP_001 LASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL
      520       530       540       550     

>>NP_009177 (OMIM: 605774) kelch-like protein 2 isoform   (593 aa)
 initn: 1319 init1: 938 opt: 1490  Z-score: 1634.3  bits: 312.3 E(85289): 2.7e-84
Smith-Waterman score: 1490; 43.3% identity (70.8% similar) in 559 aa overlap (15-565:38-589)

                               10        20        30        40    
pF1KB5                 MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDF
                                     : :. .. :: ::..: :::::. .:. ..
NP_009 PACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEI
        10        20        30        40        50        60       

           50        60        70        80        90       100    
pF1KB5 PAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQ
        :::.:::::: :: ::::.:.::.    : :. . . :...:.:.:::  ..:: ::::
NP_009 SAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQ
        70        80        90       100       110       120       

          110       120       130       140       150       160    
pF1KB5 ELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPE
        ::::: ::::. ::..::::::::: : :::::: ::. : :.::.. :......:: .
NP_009 VLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFAD
       130       140       150       160       170       180       

          170       180       190       200       210       220    
pF1KB5 VVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRM
       ::  :::. :.  .: .::. :.. ..::: :::::: ::.: :  :.: .  :...::.
NP_009 VVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRL
       190       200       210       220       230       240       

          230       240       250       260        270       280   
pF1KB5 PLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRP-ELRSQMQGPRTRARLGAN--E
       :::  .:... .. : ... :  :.: . :: :.:: : : :  :.. ::: :   :  .
NP_009 PLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSVRTRLRTPMNLPK
       250       260       270       280       290       300       

             290         300       310       320       330         
pF1KB5 VLLVVGGFGSQQSP--IDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDG
       ...::::    :.:  :  :: :: : ..:  .  .  .:  .. : .   ....::..:
NP_009 LMVVVGG----QAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNG
       310           320       330       340       350       360   

     340       350       360       370       380       390         
pF1KB5 RSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERY
         :. .:.  : . :.   : ::: :  ::.  ::..:. ..:. ::::::   .:.: :
NP_009 SLRVRTVDSYDPVKDQ---WTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAY
           370          380       390       400       410       420

     400       410       420       430         440       450       
pF1KB5 DPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLN--ILNSVEKYDPHTGHWTNVT
       . . ..:  .. :.: : ..:. :..:..: .::::: .   :..:: :.  :..:: ..
NP_009 NIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATTNEWTYIA
              430       440       450       460       470       480

       460       470       480       490       500       510       
pF1KB5 PMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATV
        :.:.::::::..::. .:.::: ::    .:::.:.  :..:  :..:.  :  .:. .
NP_009 EMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCA
              490       500       510       520       530       540

       520       530       540       550        560         
pF1KB5 LRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTS-MGTQRCDAGVCVLREK 
       . : ::...: ::.  :.:.: :.:  :.: ::.: :.: :  ::: :.    
NP_009 VNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL
              550       560       570       580       590   




568 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:51:21 2016 done: Sat Nov  5 10:51:23 2016
 Total Scan time:  9.590 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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