Result of FASTA (omim) for pF1KB5905
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5905, 502 aa
  1>>>pF1KB5905 502 - 502 aa - 502 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.0667+/-0.000697; mu= -20.3246+/- 0.040
 mean_var=796.3591+/-186.075, 0's: 0 Z-trim(115.1): 117  B-trim: 513 in 1/49
 Lambda= 0.045449
 statistics sampled from 25178 (25272) to 25178 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.296), width:  16
 Scan time:  6.690

The best scores are:                                      opt bits E(85289)
XP_016864048 (OMIM: 112600,603248,609441,616849) P ( 502) 3430 241.4 4.5e-63
XP_016864049 (OMIM: 112600,603248,609441,616849) P ( 502) 3430 241.4 4.5e-63
XP_016864050 (OMIM: 112600,603248,609441,616849) P ( 502) 3430 241.4 4.5e-63
XP_011530503 (OMIM: 112600,603248,609441,616849) P ( 502) 3430 241.4 4.5e-63
NP_001243723 (OMIM: 112600,603248,609441,616849) b ( 502) 3430 241.4 4.5e-63
NP_001194 (OMIM: 112600,603248,609441,616849) bone ( 502) 3430 241.4 4.5e-63
XP_016864047 (OMIM: 112600,603248,609441,616849) P ( 502) 3430 241.4 4.5e-63
NP_001243721 (OMIM: 112600,603248,609441,616849) b ( 502) 3430 241.4 4.5e-63
NP_001243722 (OMIM: 112600,603248,609441,616849) b ( 532) 3430 241.5 4.7e-63
NP_004320 (OMIM: 174900,601299,610069) bone morpho ( 532) 2520 181.8 4.3e-45
XP_011538406 (OMIM: 174900,601299,610069) PREDICTE ( 532) 2520 181.8 4.3e-45
XP_011538405 (OMIM: 174900,601299,610069) PREDICTE ( 532) 2520 181.8 4.3e-45
NP_001293139 (OMIM: 132800,190181) TGF-beta recept ( 507) 1708 128.5 4.4e-29
NP_004603 (OMIM: 132800,190181) TGF-beta receptor  ( 503) 1695 127.7 7.9e-29
XP_011517250 (OMIM: 132800,190181) PREDICTED: TGF- ( 438) 1632 123.5 1.3e-27
XP_016870552 (OMIM: 132800,190181) PREDICTED: TGF- ( 438) 1632 123.5 1.3e-27
XP_011517251 (OMIM: 132800,190181) PREDICTED: TGF- ( 434) 1619 122.6 2.3e-27
NP_004293 (OMIM: 601300) activin receptor type-1B  ( 505) 1616 122.5 2.9e-27
XP_011510408 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
NP_001104537 (OMIM: 102576,135100) activin recepto ( 509) 1600 121.5   6e-27
XP_006712888 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
XP_011510410 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
XP_005246997 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
NP_001096 (OMIM: 102576,135100) activin receptor t ( 509) 1600 121.5   6e-27
XP_005246996 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
XP_011510409 (OMIM: 102576,135100) PREDICTED: acti ( 509) 1600 121.5   6e-27
NP_660302 (OMIM: 608981) activin receptor type-1C  ( 493) 1584 120.4 1.2e-26
NP_064732 (OMIM: 601300) activin receptor type-1B  ( 453) 1573 119.6 1.9e-26
NP_001104501 (OMIM: 608981) activin receptor type- ( 443) 1532 116.9 1.2e-25
XP_011517252 (OMIM: 132800,190181) PREDICTED: TGF- ( 357) 1492 114.2 6.6e-25
NP_001124388 (OMIM: 132800,190181) TGF-beta recept ( 426) 1492 114.3 7.3e-25
NP_001070869 (OMIM: 600376,601284) serine/threonin ( 503) 1434 110.6 1.1e-23
XP_005269292 (OMIM: 600376,601284) PREDICTED: seri ( 503) 1434 110.6 1.1e-23
NP_000011 (OMIM: 600376,601284) serine/threonine-p ( 503) 1434 110.6 1.1e-23
NP_001104502 (OMIM: 608981) activin receptor type- ( 413) 1398 108.1 5.1e-23
XP_011537310 (OMIM: 600376,601284) PREDICTED: seri ( 413) 1216 96.2   2e-19
XP_016875688 (OMIM: 601300) PREDICTED: activin rec ( 494) 1070 86.7 1.7e-16
XP_016875689 (OMIM: 601300) PREDICTED: activin rec ( 494) 1070 86.7 1.7e-16
NP_064733 (OMIM: 601300) activin receptor type-1B  ( 546) 1070 86.7 1.8e-16
XP_016875690 (OMIM: 601300) PREDICTED: activin rec ( 381) 1030 83.9   9e-16
NP_001104503 (OMIM: 608981) activin receptor type- ( 336) 1021 83.2 1.3e-15
NP_001265509 (OMIM: 102581) activin receptor type- ( 405)  780 67.6   8e-11
NP_001607 (OMIM: 102581) activin receptor type-2A  ( 513)  780 67.7 9.2e-11
NP_001265508 (OMIM: 102581) activin receptor type- ( 513)  780 67.7 9.2e-11
XP_016863005 (OMIM: 602730,613751) PREDICTED: acti ( 511)  743 65.3 4.9e-10
NP_001097 (OMIM: 602730,613751) activin receptor t ( 512)  743 65.3 4.9e-10
XP_016863004 (OMIM: 602730,613751) PREDICTED: acti ( 518)  743 65.3   5e-10
XP_016863003 (OMIM: 602730,613751) PREDICTED: acti ( 526)  743 65.3   5e-10
XP_005265640 (OMIM: 602730,613751) PREDICTED: acti ( 533)  743 65.3 5.1e-10
XP_011532347 (OMIM: 133239,190182,610168,614331) P ( 532)  728 64.3   1e-09


>>XP_016864048 (OMIM: 112600,603248,609441,616849) PREDI  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
XP_016 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>XP_016864049 (OMIM: 112600,603248,609441,616849) PREDI  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
XP_016 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>XP_016864050 (OMIM: 112600,603248,609441,616849) PREDI  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
XP_016 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>XP_011530503 (OMIM: 112600,603248,609441,616849) PREDI  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
XP_011 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>NP_001243723 (OMIM: 112600,603248,609441,616849) bone   (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
NP_001 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>NP_001194 (OMIM: 112600,603248,609441,616849) bone mor  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
NP_001 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>XP_016864047 (OMIM: 112600,603248,609441,616849) PREDI  (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
XP_016 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>NP_001243721 (OMIM: 112600,603248,609441,616849) bone   (502 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.3  bits: 241.4 E(85289): 4.5e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)

               10        20        30        40        50        60
pF1KB5 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPAS
              430       440       450       460       470       480

              490       500  
pF1KB5 RLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::
NP_001 RLTALRVKKTLAKMSESQDIKL
              490       500  

>>NP_001243722 (OMIM: 112600,603248,609441,616849) bone   (532 aa)
 initn: 3430 init1: 3430 opt: 3430  Z-score: 1253.1  bits: 241.5 E(85289): 4.7e-63
Smith-Waterman score: 3430; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:31-532)

                                             10        20        30
pF1KB5                               MLLRSAGKLNVGTKKEDGESTAPTPRPKVL
                                     ::::::::::::::::::::::::::::::
NP_001 MGWLEELNWQLHIFLLILLSMHTRANFLDNMLLRSAGKLNVGTKKEDGESTAPTPRPKVL
               10        20        30        40        50        60

               40        50        60        70        80        90
pF1KB5 RCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQR
               70        80        90       100       110       120

              100       110       120       130       140       150
pF1KB5 RSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRY
              130       140       150       160       170       180

              160       170       180       190       200       210
pF1KB5 KRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQI
              190       200       210       220       230       240

              220       230       240       250       260       270
pF1KB5 GKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTG
              250       260       270       280       290       300

              280       290       300       310       320       330
pF1KB5 SWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAH
              310       320       330       340       350       360

              340       350       360       370       380       390
pF1KB5 RDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRN
              370       380       390       400       410       420

              400       410       420       430       440       450
pF1KB5 HFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLR
              430       440       450       460       470       480

              460       470       480       490       500  
pF1KB5 PSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
              490       500       510       520       530  

>>NP_004320 (OMIM: 174900,601299,610069) bone morphogene  (532 aa)
 initn: 2406 init1: 2040 opt: 2520  Z-score: 930.6  bits: 181.8 E(85289): 4.3e-45
Smith-Waterman score: 2520; 73.3% identity (88.2% similar) in 491 aa overlap (14-502:43-532)

                                10        20        30        40   
pF1KB5                  MLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCHHHCPEDSV
                                     :.:.: . ::      :.: :  :::.:..
NP_004 AYLFIISRVQGQNLDSMLHGTGMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAI
             20        30        40        50        60        70  

            50        60        70        80        90       100   
pF1KB5 NNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECN
       :: : :.:.::..:::::.:  ...:::.  :::::::.:.:  . ::.:::: . : ::
NP_004 NNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECC-RTNLCN
             80        90       100       110       120        130 

           110       120       130       140        150        160 
pF1KB5 KDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLII-LFCYFRY-KRQETRPRYSI
       . :.:::::.    : :: :.  .::::..:: . ....   ::: .: :   .: ::. 
NP_004 QYLQPTLPPVVIGPFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKHYCKSISSRRRYNR
             140       150       160       170       180       190 

             170       180       190       200       210       220 
pF1KB5 GLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMG
        :::::..:: ::::.:::.::::::::::::::::::::::::::.:.:::::::::::
NP_004 DLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMG
             200       210       220       230       240       250 

             230       240       250       260       270       280 
pF1KB5 KWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDY
             260       270       280       290       300       310 

             290       300       310       320       330       340 
pF1KB5 HENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVK
       ::::::::.:: .:::....::::::.. :::::::::..::::::::::::::::::.:
NP_004 HENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIK
             320       330       340       350       360       370 

             350       360       370       380       390       400 
pF1KB5 KNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMY
       :::.:::::::::::: :::::::.: :::::::::: :::::::::.:::: :::::.:
NP_004 KNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIY
             380       390       400       410       420       430 

             410       420       430       440       450       460 
pF1KB5 SFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDE
       :::::.::.::::..:::::::::::...::::::::::::.::.:.:::   :::.:::
NP_004 SFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDE
             440       450       460       470       480       490 

             470       480       490       500  
pF1KB5 CLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL
       ::: . :::.:::::::::::::::.::::::: ::::.:.
NP_004 CLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI
             500       510       520       530  




502 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:38:14 2016 done: Sat Nov  5 10:38:15 2016
 Total Scan time:  6.690 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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