Result of FASTA (omim) for pF1KB5842
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5842, 483 aa
  1>>>pF1KB5842 483 - 483 aa - 483 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1347+/-0.000397; mu= 14.2278+/- 0.025
 mean_var=75.8665+/-15.389, 0's: 0 Z-trim(112.8): 161  B-trim: 730 in 2/49
 Lambda= 0.147248
 statistics sampled from 21632 (21815) to 21632 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.256), width:  16
 Scan time:  8.660

The best scores are:                                      opt bits E(85289)
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 3164 681.7 1.2e-195
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 3164 681.7 1.2e-195
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 3164 681.7 1.2e-195
XP_016872740 (OMIM: 600326) PREDICTED: probable AT ( 440) 1873 407.4 4.1e-113
XP_011540946 (OMIM: 600326) PREDICTED: probable AT ( 440) 1873 407.4 4.1e-113
XP_011540947 (OMIM: 600326) PREDICTED: probable AT ( 434) 1760 383.4 6.8e-106
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411)  948 210.9 5.4e-54
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406)  943 209.9 1.1e-53
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407)  930 207.1 7.6e-53
NP_542165 (OMIM: 142560) spliceosome RNA helicase  ( 428)  838 187.6 6.1e-47
NP_004631 (OMIM: 142560) spliceosome RNA helicase  ( 428)  838 187.6 6.1e-47
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455)  744 167.6 6.6e-41
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482)  734 165.5   3e-40
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483)  734 165.5   3e-40
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486)  734 165.5 3.1e-40
NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479)  719 162.3 2.8e-39
XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484)  719 162.3 2.8e-39
XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539)  719 162.3 3.1e-39
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390)  699 158.0 4.3e-38
NP_001191439 (OMIM: 602641) eukaryotic initiation  ( 347)  697 157.6 5.3e-38
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619)  686 155.3 4.5e-37
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619)  686 155.3 4.5e-37
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619)  686 155.3 4.5e-37
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619)  686 155.3 4.5e-37
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369)  681 154.2 5.9e-37
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529)  683 154.7   6e-37
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529)  683 154.7   6e-37
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604)  683 154.7 6.8e-37
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648)  683 154.7 7.3e-37
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439)  679 153.8 9.2e-37
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881)  681 154.3 1.3e-36
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882)  681 154.3 1.3e-36
NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370)  671 152.1 2.6e-36
NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370)  671 152.1 2.6e-36
XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370)  671 152.1 2.6e-36
NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370)  671 152.1 2.6e-36
XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370)  671 152.1 2.6e-36
NP_004389 (OMIM: 601235) probable ATP-dependent RN ( 875)  667 151.3   1e-35
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796)  636 144.7 8.8e-34
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775)  621 141.5 7.9e-33
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938)  621 141.6 9.3e-33
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938)  621 141.6 9.3e-33
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938)  621 141.6 9.3e-33
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938)  621 141.6 9.3e-33
NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448)  616 140.4   1e-32
NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453)  616 140.4   1e-32
XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508)  616 140.4 1.1e-32
NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567)  610 139.2   3e-32
XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557)  607 138.5 4.6e-32
XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674)  599 136.8 1.8e-31


>>NP_004388 (OMIM: 600326) probable ATP-dependent RNA he  (483 aa)
 initn: 3164 init1: 3164 opt: 3164  Z-score: 3633.3  bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
              430       440       450       460       470       480

          
pF1KB5 EKP
       :::
NP_004 EKP
          

>>NP_001244120 (OMIM: 600326) probable ATP-dependent RNA  (483 aa)
 initn: 3164 init1: 3164 opt: 3164  Z-score: 3633.3  bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
              430       440       450       460       470       480

          
pF1KB5 EKP
       :::
NP_001 EKP
          

>>XP_005271474 (OMIM: 600326) PREDICTED: probable ATP-de  (483 aa)
 initn: 3164 init1: 3164 opt: 3164  Z-score: 3633.3  bits: 681.7 E(85289): 1.2e-195
Smith-Waterman score: 3164; 100.0% identity (100.0% similar) in 483 aa overlap (1-483:1-483)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
              430       440       450       460       470       480

          
pF1KB5 EKP
       :::
XP_005 EKP
          

>>XP_016872740 (OMIM: 600326) PREDICTED: probable ATP-de  (440 aa)
 initn: 2869 init1: 1867 opt: 1873  Z-score: 2151.8  bits: 407.4 E(85289): 4.1e-113
Smith-Waterman score: 2787; 91.1% identity (91.1% similar) in 483 aa overlap (1-483:1-440)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_016 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
                                      :::::::::::::::::::::::::::::
XP_016 -------------------------------LQINQSIIFCNSSQRVELLAKKISQLGYS
                                     290       300       310       

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       320       330       340       350       360       370       

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       380       390       400       410       420       430       

          
pF1KB5 EKP
       :::
XP_016 EKP
       440

>>XP_011540946 (OMIM: 600326) PREDICTED: probable ATP-de  (440 aa)
 initn: 2869 init1: 1867 opt: 1873  Z-score: 2151.8  bits: 407.4 E(85289): 4.1e-113
Smith-Waterman score: 2787; 91.1% identity (91.1% similar) in 483 aa overlap (1-483:1-440)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::            
XP_011 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM------------
              250       260       270       280                    

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
                                      :::::::::::::::::::::::::::::
XP_011 -------------------------------LQINQSIIFCNSSQRVELLAKKISQLGYS
                                     290       300       310       

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       320       330       340       350       360       370       

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       380       390       400       410       420       430       

          
pF1KB5 EKP
       :::
XP_011 EKP
       440

>>XP_011540947 (OMIM: 600326) PREDICTED: probable ATP-de  (434 aa)
 initn: 1753 init1: 1753 opt: 1760  Z-score: 2022.2  bits: 383.4 E(85289): 6.8e-106
Smith-Waterman score: 2744; 89.9% identity (89.9% similar) in 483 aa overlap (1-483:1-434)

               10        20        30        40        50        60
pF1KB5 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_011 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQ--------------
              130       140       150       160                    

              190       200       210       220       230       240
pF1KB5 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
                                          :::::::::::::::::::::::::
XP_011 -----------------------------------VHVVIATPGRILDLIKKGVAKVDHV
                                           170       180       190 

              250       260       270       280       290       300
pF1KB5 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
             200       210       220       230       240       250 

              310       320       330       340       350       360
pF1KB5 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
             260       270       280       290       300       310 

              370       380       390       400       410       420
pF1KB5 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
             320       330       340       350       360       370 

              430       440       450       460       470       480
pF1KB5 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
             380       390       400       410       420       430 

          
pF1KB5 EKP
       :::
XP_011 EKP
          

>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation   (411 aa)
 initn: 865 init1: 372 opt: 948  Z-score: 1090.3  bits: 210.9 E(85289): 5.4e-54
Smith-Waterman score: 948; 36.8% identity (71.7% similar) in 410 aa overlap (63-464:4-407)

             40        50        60        70        80            
pF1KB5 GGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDL---RIKTS-
                                     :.:.  . . .: : :  .:.   ...:: 
NP_055                            MATTATMATSGSARKRL-LKEEDMTKVEFETSE
                                          10         20        30  

         90       100       110       120       130       140      
pF1KB5 --DVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGK
         ::: :    :. . :...:: ::. .:.:::: ::...:   ..:::..:....::::
NP_055 EVDVTPT----FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGK
                 40        50        60        70        80        

        150       160       170       180       190       200      
pF1KB5 SGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR
       .... : .:. ::..  . ::....::::::.:...  . .. .:. ..  :  ::::. 
NP_055 TATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVG
       90       100       110       120       130        140       

        210       220       230       240       250       260      
pF1KB5 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILT
       .:: .::   ::: .::::..:.:..   ..  ..:.::::::..:.. : . . :.   
NP_055 EDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY
       150       160       170       180       190       200       

        270       280       290       300        310        320    
pF1KB5 LPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHC
       ::   :..: :::.:  . .. :. .  : .: .  .::::.:. :... :  :. :   
NP_055 LPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDT
       210       220       230       240       250       260       

          330       340       350       360       370       380    
pF1KB5 LNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGL
       :  :.. : :.:..::::....:. :..:. . ...   .:. : :..:. ....::.: 
NP_055 LCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGA
       270       280       290       300       310       320       

          390       400       410       420       430       440    
pF1KB5 CRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRF
        : :. ::...::.:.  :...::.:.:.  : :.::::::::.:. :.:::..  ::  
NP_055 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIR
       330       340       350       360       370       380       

          450       460       470       480   
pF1KB5 NLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
        :..::.  .:.:  .: :.                   
NP_055 ILRDIEQYYSTQIDEMPMNVADLI               
       390       400       410                

>>NP_001407 (OMIM: 602641) eukaryotic initiation factor   (406 aa)
 initn: 790 init1: 446 opt: 943  Z-score: 1084.6  bits: 209.9 E(85289): 1.1e-53
Smith-Waterman score: 943; 38.7% identity (74.2% similar) in 372 aa overlap (96-464:32-402)

          70        80        90       100       110       120     
pF1KB5 IKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEE
                                     . :.:. :.. :: ::. .:.:::: ::..
NP_001 SASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQR
              10        20        30        40        50        60 

         130       140       150       160       170       180     
pF1KB5 SIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICI
       .:   ..: :..:.:..::::.... : .:....:     ::.:..:::::: :.... .
NP_001 AILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVM
              70        80        90       100       110       120 

         190       200       210        220       230       240    
pF1KB5 QVSKHMGGAKVMATTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIV
        .. .:: :.  :  ::::.: ....:. .. :....::::..:....   .  ...:.:
NP_001 ALGDYMG-ASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV
              130       140       150       160       170       180

          250       260       270       280       290       300    
pF1KB5 LDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EE
       :::::..::. : . . ::.  : .: :..: :::.: .: .  .. .. : .: .  ::
NP_001 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE
              190       200       210       220       230       240

           310        320       330       340       350       360  
pF1KB5 LTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCF
       :::.:. :.:  :  :. :.  :  :.  : :.:..:: :. ..:. :..:.    ..  
NP_001 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS
              250       260       270       280       290       300

            370       380       390       400       410       420  
pF1KB5 YIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRI
        .:. : :..:. ....::.:  : :. :::..::::.: :..:::.:.:   :.:.:::
NP_001 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
              310       320       330       340       350       360

            430       440       450       460       470       480  
pF1KB5 GRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEK
       ::.::::. :.:::..: .:. .:..::   .: :. .: :.                  
NP_001 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI              
              370       380       390       400                    

        
pF1KB5 P

>>NP_001958 (OMIM: 601102) eukaryotic initiation factor   (407 aa)
 initn: 778 init1: 439 opt: 930  Z-score: 1069.7  bits: 207.1 E(85289): 7.6e-53
Smith-Waterman score: 930; 38.4% identity (74.2% similar) in 372 aa overlap (96-464:33-403)

          70        80        90       100       110       120     
pF1KB5 IKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEE
                                     ..:.:. ::. :: ::. .:.:::: ::..
NP_001 GGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQR
             10        20        30        40        50        60  

         130       140       150       160       170       180     
pF1KB5 SIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICI
       .:   ..: :..:.:..::::.... : .:..:...  . ::.:..:::::: :.... .
NP_001 AIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVIL
             70        80        90       100       110       120  

         190       200       210        220       230       240    
pF1KB5 QVSKHMGGAKVMATTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIV
        .. .:: :   :  ::::.:.....:. .. :.:..::::..:....   .   ..:.:
NP_001 ALGDYMG-ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFV
             130       140       150       160       170       180 

          250       260       270       280       290       300    
pF1KB5 LDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EE
       :::::..::. : . . .:.  :  . :..: :::.: .: .  .. .. : .: .  ::
NP_001 LDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEE
             190       200       210       220       230       240 

           310        320       330       340       350       360  
pF1KB5 LTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCF
       :::.:. :.:  :  :. :.  :  :.  : :.:..:: :. ..:. :..:.    ..  
NP_001 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS
             250       260       270       280       290       300 

            370       380       390       400       410       420  
pF1KB5 YIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRI
        .:. : :..:. ....::.:  : :. :::..::::.: :..:::.:.:   :.:.:::
NP_001 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
             310       320       330       340       350       360 

            430       440       450       460       470       480  
pF1KB5 GRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEK
       ::.::::. :.:::..: .:.  :..::   .: .. .: :.                  
NP_001 GRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI              
             370       380       390       400                     

        
pF1KB5 P

>>NP_542165 (OMIM: 142560) spliceosome RNA helicase DDX3  (428 aa)
 initn: 723 init1: 349 opt: 838  Z-score: 963.7  bits: 187.6 E(85289): 6.1e-47
Smith-Waterman score: 838; 34.7% identity (67.8% similar) in 429 aa overlap (49-472:4-426)

       20        30        40        50        60        70        
pF1KB5 GQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKL
                                     : ..:   .  .. . :   ::  .   : 
NP_542                            MAENDVDNELLDYEDDEVETAAGGDGAEAPAK-
                                          10        20        30   

       80        90       100       110       120       130        
pF1KB5 PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA
         ::  .: : : : ... :.:. :: ::: .: . :.:.:: .:.: :: :. : :.: 
NP_542 --KD--VKGSYV-SIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC
                 40         50        60        70        80       

      140       150       160       170       180       190        
pF1KB5 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA
       .::.: ::......  :..:.    .....:.  :::::.:.:.   . ::.: ..:: .
NP_542 QAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAV
        90       100       110       120       130       140       

      200       210        220       230       240       250       
pF1KB5 TTGGTNLRDDIMRLDDTV-HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF
         :: ... :   :  .  :.:..:::::: : ..   .. :.. ..::: ::.: : :.
NP_542 FFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDM
       150       160       170       180       190       200       

        260       270       280       290       300         310    
pF1KB5 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA
        . ...:.   :...:....:::.   ..    . .: :.:: . .:  :::.:. :::.
NP_542 RRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYV
       210       220       230       240       250       260       

          320       330       340       350       360       370    
pF1KB5 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN
        . . .: . :  :.. :..:: .:: .: ::   ::. . . ..  . ::  : ::.: 
NP_542 KLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL
       270       280       290       300       310       320       

          380       390       400       410       420       430    
pF1KB5 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA
         ...:..   : :: :.:: ::.::. ::...:.:.:. ..:::::..:.::::  :::
NP_542 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLA
       330       340       350       360       370       380       

           440       450       460       470       480   
pF1KB5 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
       :....  .:   :....... ..:. .:..:: : :. .           
NP_542 ITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR         
       390       400       410       420                 




483 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:28:47 2016 done: Sat Nov  5 10:28:49 2016
 Total Scan time:  8.660 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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