Result of FASTA (omim) for pF1KB7955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7955, 256 aa
  1>>>pF1KB7955 256 - 256 aa - 256 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6737+/-0.000346; mu= 18.1086+/- 0.022
 mean_var=58.9190+/-11.827, 0's: 0 Z-trim(113.9): 14  B-trim: 42 in 1/52
 Lambda= 0.167088
 statistics sampled from 23399 (23413) to 23399 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.275), width:  16
 Scan time:  6.080

The best scores are:                                      opt bits E(85289)
NP_006784 (OMIM: 604769) thioredoxin-dependent per ( 256) 1701 418.1 7.6e-117
NP_001289201 (OMIM: 604769) thioredoxin-dependent  ( 198) 1214 300.6 1.4e-81
XP_005274495 (OMIM: 300927) PREDICTED: peroxiredox ( 257)  912 227.9 1.4e-59
NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor ( 271)  911 227.7 1.7e-59
NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sap ( 198)  881 220.4   2e-57
NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199)  876 219.2 4.6e-57
NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199)  876 219.2 4.6e-57
NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo  ( 199)  876 219.2 4.6e-57
NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199)  876 219.2 4.6e-57
XP_016884720 (OMIM: 300927) PREDICTED: peroxiredox ( 336)  861 215.7 8.4e-56
XP_016884719 (OMIM: 300927) PREDICTED: peroxiredox ( 350)  860 215.5   1e-55
NP_004896 (OMIM: 602316) peroxiredoxin-6 [Homo sap ( 224)  156 45.6 8.9e-05
NP_036226 (OMIM: 606583) peroxiredoxin-5, mitochon ( 214)  141 42.0   0.001


>>NP_006784 (OMIM: 604769) thioredoxin-dependent peroxid  (256 aa)
 initn: 1701 init1: 1701 opt: 1701  Z-score: 2218.8  bits: 418.1 E(85289): 7.6e-117
Smith-Waterman score: 1701; 100.0% identity (100.0% similar) in 256 aa overlap (1-256:1-256)

               10        20        30        40        50        60
pF1KB7 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
              190       200       210       220       230       240

              250      
pF1KB7 KPSPAASKEYFQKVNQ
       ::::::::::::::::
NP_006 KPSPAASKEYFQKVNQ
              250      

>>NP_001289201 (OMIM: 604769) thioredoxin-dependent pero  (198 aa)
 initn: 1214 init1: 1214 opt: 1214  Z-score: 1585.9  bits: 300.6 E(85289): 1.4e-81
Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)

               10        20        30        40        50        60
pF1KB7 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKAN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 LALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTI
       ::::                                                        
NP_001 LALRSSQVQLLPKSTFRR                                          
              190                                                  

>>XP_005274495 (OMIM: 300927) PREDICTED: peroxiredoxin-4  (257 aa)
 initn: 905 init1: 905 opt: 912  Z-score: 1190.8  bits: 227.9 E(85289): 1.4e-59
Smith-Waterman score: 912; 67.0% identity (90.6% similar) in 191 aa overlap (65-255:67-257)

           40        50        60        70        80        90    
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
                                     :.. :::..::::..::::.:.: :..:::
XP_005 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
         40        50        60        70        80        90      

          100       110       120       130       140       150    
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
       ::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
XP_005 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
        100       110       120       130       140       150      

          160       170       180       190       200       210    
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
        . : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
XP_005 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
        160       170       180       190       200       210      

          220       230       240       250      
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       ::.::::.. :::::::.: : : :: :.::.. .::.:.: 
XP_005 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN 
        220       230       240       250        

>>NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor [Ho  (271 aa)
 initn: 924 init1: 905 opt: 911  Z-score: 1189.2  bits: 227.7 E(85289): 1.7e-59
Smith-Waterman score: 911; 66.5% identity (90.6% similar) in 191 aa overlap (65-255:81-271)

           40        50        60        70        80        90    
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
                                     ... :::..::::..::::.:.: :..:::
NP_006 CHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKY
               60        70        80        90       100       110

          100       110       120       130       140       150    
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
       ::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
NP_006 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
              120       130       140       150       160       170

          160       170       180       190       200       210    
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
        . : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
NP_006 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
              180       190       200       210       220       230

          220       230       240       250      
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       ::.::::.. :::::::.: : : :: :.::.. .::.:.: 
NP_006 LVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN 
              240       250       260       270  

>>NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sapiens  (198 aa)
 initn: 879 init1: 879 opt: 881  Z-score: 1152.0  bits: 220.4 E(85289): 2e-57
Smith-Waterman score: 881; 65.4% identity (89.0% similar) in 191 aa overlap (65-255:8-198)

           40        50        60        70        80        90    
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
                                     . . :: ::.::::.: ::...:.:.::::
NP_005                        MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKY
                                      10        20        30       

          100       110       120       130       140       150    
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
       .:::::::::::::::::.:::..:..:. ..:::..:::::.:.::::::::::.::::
NP_005 VVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLG
        40        50        60        70        80        90       

          160       170       180       190       200       210    
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
        .:: ::.:.:...:.:::::    :.: ::::::: .::.....::::::::::.:.::
NP_005 PLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALR
       100       110       120       130       140       150       

          220       230       240       250      
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       ::.::::.. :::::::.: : : ::::.   :::::.: : 
NP_005 LVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN 
       160       170       180       190         

>>NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 862 init1: 832 opt: 876  Z-score: 1145.5  bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)

           40        50        60        70         80        90   
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
                                     . . :: ::.:::. .:.:::.::.:.:::
NP_859                        MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
                                      10        20        30       

           100       110       120       130       140       150   
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
       :.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_859 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
        40        50        60        70        80        90       

           160       170       180       190       200       210   
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
       : ::: :.::  . :..:::::    :...::::::: .:......::::::::::.:::
NP_859 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
       100       110       120       130       140       150       

           220       230       240       250      
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       :::.:::... :::::::.: : : ::::.   :::::.:   
NP_859 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK 
       160       170       180       190          

>>NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 862 init1: 832 opt: 876  Z-score: 1145.5  bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)

           40        50        60        70         80        90   
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
                                     . . :: ::.:::. .:.:::.::.:.:::
NP_002                        MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
                                      10        20        30       

           100       110       120       130       140       150   
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
       :.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_002 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
        40        50        60        70        80        90       

           160       170       180       190       200       210   
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
       : ::: :.::  . :..:::::    :...::::::: .:......::::::::::.:::
NP_002 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
       100       110       120       130       140       150       

           220       230       240       250      
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       :::.:::... :::::::.: : : ::::.   :::::.:   
NP_002 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK 
       160       170       180       190          

>>NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo sapi  (199 aa)
 initn: 862 init1: 832 opt: 876  Z-score: 1145.5  bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)

           40        50        60        70         80        90   
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
                                     . . :: ::.:::. .:.:::.::.:.:::
NP_001                        MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
                                      10        20        30       

           100       110       120       130       140       150   
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
       :.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_001 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
        40        50        60        70        80        90       

           160       170       180       190       200       210   
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
       : ::: :.::  . :..:::::    :...::::::: .:......::::::::::.:::
NP_001 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
       100       110       120       130       140       150       

           220       230       240       250      
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       :::.:::... :::::::.: : : ::::.   :::::.:   
NP_001 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK 
       160       170       180       190          

>>NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 862 init1: 832 opt: 876  Z-score: 1145.5  bits: 219.2 E(85289): 4.6e-57
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (65-253:8-197)

           40        50        60        70         80        90   
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
                                     . . :: ::.:::. .:.:::.::.:.:::
NP_859                        MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
                                      10        20        30       

           100       110       120       130       140       150   
pF1KB7 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
       :.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_859 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
        40        50        60        70        80        90       

           160       170       180       190       200       210   
pF1KB7 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
       : ::: :.::  . :..:::::    :...::::::: .:......::::::::::.:::
NP_859 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
       100       110       120       130       140       150       

           220       230       240       250      
pF1KB7 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
       :::.:::... :::::::.: : : ::::.   :::::.:   
NP_859 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK 
       160       170       180       190          

>>XP_016884720 (OMIM: 300927) PREDICTED: peroxiredoxin-4  (336 aa)
 initn: 854 init1: 854 opt: 861  Z-score: 1122.8  bits: 215.7 E(85289): 8.4e-56
Smith-Waterman score: 861; 68.2% identity (90.9% similar) in 176 aa overlap (65-240:67-242)

           40        50        60        70        80        90    
pF1KB7 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
                                     :.. :::..::::..::::.:.: :..:::
XP_016 EGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYRGKY
         40        50        60        70        80        90      

          100       110       120       130       140       150    
pF1KB7 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
       ::.:::::::::::::::.::.:. .::...: :::: ::::.:.:::::::::..::::
XP_016 LVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLG
        100       110       120       130       140       150      

          160       170       180       190       200       210    
pF1KB7 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
        . : ::::::.:::.:::: :: :: .:::::::: .:.......:::::::::.::::
XP_016 PIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLR
        160       170       180       190       200       210      

          220       230       240       250                        
pF1KB7 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ                  
       ::.::::.. :::::::.: : : :.                                  
XP_016 LVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPALWEA
        220       230       240       250       260       270      




256 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:16:33 2016 done: Sat Nov  5 10:16:34 2016
 Total Scan time:  6.080 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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