Result of FASTA (ccds) for pF1KF0386
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KF0386, 674 aa
  1>>>pF1KF0386 674 - 674 aa - 674 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.9882+/-0.0012; mu= -30.8245+/- 0.073
 mean_var=735.1097+/-152.164, 0's: 0 Z-trim(117.2): 84  B-trim: 60 in 1/55
 Lambda= 0.047304
 statistics sampled from 17872 (17947) to 17872 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.551), width:  16
 Scan time:  4.970

The best scores are:                                      opt bits E(32554)
CCDS74824.1 MED15 gene_id:51586|Hs108|chr22        ( 677) 4579 327.5 3.8e-89
CCDS77653.1 MED15 gene_id:51586|Hs108|chr22        ( 722) 4081 293.6 6.7e-79
CCDS13781.1 MED15 gene_id:51586|Hs108|chr22        ( 748) 4081 293.6 6.9e-79
CCDS33602.1 MED15 gene_id:51586|Hs108|chr22        ( 788) 2922 214.5 4.7e-55


>>CCDS74824.1 MED15 gene_id:51586|Hs108|chr22             (677 aa)
 initn: 3858 init1: 3858 opt: 4579  Z-score: 1714.0  bits: 327.5 E(32554): 3.8e-89
Smith-Waterman score: 4579; 99.6% identity (99.6% similar) in 677 aa overlap (1-674:1-677)

               10        20        30        40        50        60
pF1KF0 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MDVSGQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVA
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KF0 RLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::  :::
CCDS74 RLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA
               70        80        90       100       110       120

      120       130       140        150       160       170       
pF1KF0 QQSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ
       :::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
CCDS74 QQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KF0 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KF0 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KF0 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KF0 GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KF0 YLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIA
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KF0 LEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHG
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KF0 PPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PPITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLD
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KF0 DKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DKDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTA
              610       620       630       640       650       660

       660       670    
pF1KF0 LLNTWAQSVHQACLSAA
       :::::::::::::::::
CCDS74 LLNTWAQSVHQACLSAA
              670       

>>CCDS77653.1 MED15 gene_id:51586|Hs108|chr22             (722 aa)
 initn: 3858 init1: 3858 opt: 4081  Z-score: 1530.0  bits: 293.6 E(32554): 6.7e-79
Smith-Waterman score: 4151; 89.4% identity (89.5% similar) in 706 aa overlap (43-674:17-722)

             20        30        40        50        60        70  
pF1KF0 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
                                     ::::::::::::::::::::::::::::::
CCDS77               MRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
                             10        20        30        40      

                                                                   
pF1KF0 KSQASVS-----------------------------------------------------
       :::::::                                                     
CCDS77 KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG
         50        60        70        80        90       100      

                        80        90       100       110           
pF1KF0 ------------------AQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQAQ
                         .:::::::::::::::::::::::::::::::::::  ::::
CCDS77 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ
        110       120       130       140       150       160      

     120       130       140        150       160       170        
pF1KF0 QSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
       ::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS77 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
        170       180       190       200       210       220      

      180       190       200       210       220       230        
pF1KF0 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
        230       240       250       260       270       280      

      240       250       260       270       280       290        
pF1KF0 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
        290       300       310       320       330       340      

      300       310       320       330       340       350        
pF1KF0 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
        350       360       370       380       390       400      

      360       370       380       390       400       410        
pF1KF0 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
        410       420       430       440       450       460      

      420       430       440       450       460       470        
pF1KF0 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
        470       480       490       500       510       520      

      480       490       500       510       520       530        
pF1KF0 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
        530       540       550       560       570       580      

      540       550       560       570       580       590        
pF1KF0 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
        590       600       610       620       630       640      

      600       610       620       630       640       650        
pF1KF0 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
        650       660       670       680       690       700      

      660       670    
pF1KF0 LNTWAQSVHQACLSAA
       ::::::::::::::::
CCDS77 LNTWAQSVHQACLSAA
        710       720  

>>CCDS13781.1 MED15 gene_id:51586|Hs108|chr22             (748 aa)
 initn: 3858 init1: 3858 opt: 4081  Z-score: 1529.7  bits: 293.6 E(32554): 6.9e-79
Smith-Waterman score: 4151; 89.4% identity (89.5% similar) in 706 aa overlap (43-674:43-748)

             20        30        40        50        60        70  
pF1KF0 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
                                     ::::::::::::::::::::::::::::::
CCDS13 TAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNK
             20        30        40        50        60        70  

                                                                   
pF1KF0 KSQASVS-----------------------------------------------------
       :::::::                                                     
CCDS13 KSQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPG
             80        90       100       110       120       130  

                        80        90       100       110           
pF1KF0 ------------------AQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ--FQAQ
                         .:::::::::::::::::::::::::::::::::::  ::::
CCDS13 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQ
            140       150       160       170       180       190  

     120       130       140        150       160       170        
pF1KF0 QSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
       ::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS13 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ
            200       210       220       230       240       250  

      180       190       200       210       220       230        
pF1KF0 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ
            260       270       280       290       300       310  

      240       250       260       270       280       290        
pF1KF0 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT
            320       330       340       350       360       370  

      300       310       320       330       340       350        
pF1KF0 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG
            380       390       400       410       420       430  

      360       370       380       390       400       410        
pF1KF0 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY
            440       450       460       470       480       490  

      420       430       440       450       460       470        
pF1KF0 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIAL
            500       510       520       530       540       550  

      480       490       500       510       520       530        
pF1KF0 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGP
            560       570       580       590       600       610  

      540       550       560       570       580       590        
pF1KF0 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PITAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDD
            620       630       640       650       660       670  

      600       610       620       630       640       650        
pF1KF0 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KDLPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTAL
            680       690       700       710       720       730  

      660       670    
pF1KF0 LNTWAQSVHQACLSAA
       ::::::::::::::::
CCDS13 LNTWAQSVHQACLSAA
            740        

>>CCDS33602.1 MED15 gene_id:51586|Hs108|chr22             (788 aa)
 initn: 2710 init1: 2710 opt: 2922  Z-score: 1101.9  bits: 214.5 E(32554): 4.7e-55
Smith-Waterman score: 3991; 92.5% identity (93.0% similar) in 644 aa overlap (74-674:145-788)

            50        60        70        80        90       100   
pF1KF0 HVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSAQLQLQQVALQQQQQQQQFQQQQQ
                                     : :. ..:::::::::::::::::::::::
CCDS33 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQ
          120       130       140       150       160       170    

           110         120       130       140        150       160
pF1KF0 AALQQQQQQQQQ--FQAQQSAMQQQFQAVVQQQQQLQQQQQQQ-HLIKLHHQNQQQIQQQ
       ::::::::::::  ::::::::::::::::::::::::::::: ::::::::::::::::
CCDS33 AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ
          180       190       200       210       220       230    

              170       180       190       200       210       220
pF1KF0 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH
          240       250       260       270       280       290    

              230       240       250       260       270       280
pF1KF0 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV
          300       310       320       330       340       350    

              290       300       310                              
pF1KF0 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ------------------------------
       ::::::::::::::::::::::::::::::                              
CCDS33 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS
          360       370       380       390       400       410    

                        320       330       340       350       360
pF1KF0 ----------VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 IPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA
          420       430       440       450       460       470    

              370       380       390       400       410       420
pF1KF0 PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLD
          480       490       500       510       520       530    

              430       440       450       460       470       480
pF1KF0 KLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEK
          540       550       560       570       580       590    

              490       500       510       520       530       540
pF1KF0 LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPI
          600       610       620       630       640       650    

              550       560       570       580       590       600
pF1KF0 TAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TAPVVCTRKRRLEDDERQSIPSVLQGEVARLDPKFLVNLDPSHCSNNGTVHLICKLDDKD
          660       670       680       690       700       710    

              610       620       630       640       650       660
pF1KF0 LPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LPSVPPLELSVPADYPAQSPLWIDRQWQYDANPFLQSVHRCMTSRLLQLPDKHSVTALLN
          720       730       740       750       760       770    

              670    
pF1KF0 TWAQSVHQACLSAA
       ::::::::::::::
CCDS33 TWAQSVHQACLSAA
          780        




674 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:11:36 2016 done: Fri Nov  4 20:11:37 2016
 Total Scan time:  4.970 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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