Result of FASTA (omim) for pF1KF0068
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KF0068, 1191 aa
  1>>>pF1KF0068 1191 - 1191 aa - 1191 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0452+/-0.000361; mu= 10.3901+/- 0.023
 mean_var=175.4140+/-35.812, 0's: 0 Z-trim(119.4): 176  B-trim: 286 in 1/58
 Lambda= 0.096837
 statistics sampled from 33103 (33305) to 33103 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.39), width:  16
 Scan time: 17.660

The best scores are:                                      opt bits E(85289)
XP_011521290 (OMIM: 609526) PREDICTED: puratrophin (1191) 8084 1142.6       0
XP_011521287 (OMIM: 609526) PREDICTED: puratrophin (1191) 8084 1142.6       0
XP_011521288 (OMIM: 609526) PREDICTED: puratrophin (1191) 8084 1142.6       0
NP_001123201 (OMIM: 609526) puratrophin-1 isoform  (1191) 8084 1142.6       0
NP_001123199 (OMIM: 609526) puratrophin-1 isoform  (1191) 8084 1142.6       0
NP_001123200 (OMIM: 609526) puratrophin-1 isoform  (1191) 8084 1142.6       0
XP_011521289 (OMIM: 609526) PREDICTED: puratrophin (1191) 8084 1142.6       0
NP_001123203 (OMIM: 609526) puratrophin-1 isoform  (1110) 6740 954.8       0
XP_016876923 (OMIM: 610018) PREDICTED: rho guanine (1331) 1180 178.1 3.3e-43
NP_060541 (OMIM: 610018) rho guanine nucleotide ex (1519) 1180 178.1 3.6e-43
XP_011535239 (OMIM: 610018) PREDICTED: rho guanine (1523) 1180 178.1 3.7e-43
XP_005267901 (OMIM: 610018) PREDICTED: rho guanine (1471) 1133 171.6 3.4e-41
NP_001265458 (OMIM: 610018) rho guanine nucleotide ( 805)  969 148.5 1.7e-34
XP_016876924 (OMIM: 610018) PREDICTED: rho guanine ( 809)  969 148.5 1.7e-34
XP_016876925 (OMIM: 610018) PREDICTED: rho guanine ( 809)  969 148.5 1.7e-34
XP_016876926 (OMIM: 610018) PREDICTED: rho guanine ( 757)  922 141.9 1.5e-32
NP_001265459 (OMIM: 610018) rho guanine nucleotide ( 757)  922 141.9 1.5e-32
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612)  654 104.8 7.4e-21
XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880)  654 104.9 7.9e-21
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038)  654 104.9 8.3e-21
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048)  654 104.9 8.3e-21
XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058)  654 104.9 8.3e-21
XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076)  654 104.9 8.3e-21
XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093)  654 104.9 8.4e-21
NP_009049 (OMIM: 601893,617061) triple functional  (3097)  654 104.9 8.4e-21
NP_001309930 (OMIM: 604605,608901) kalirin isoform ( 667)  632 101.3 2.1e-20
NP_001309929 (OMIM: 604605,608901) kalirin isoform ( 668)  632 101.3 2.1e-20
NP_001309928 (OMIM: 604605,608901) kalirin isoform ( 668)  632 101.3 2.1e-20
NP_001309927 (OMIM: 604605,608901) kalirin isoform ( 669)  632 101.3 2.1e-20
NP_001309926 (OMIM: 604605,608901) kalirin isoform ( 699)  630 101.1 2.7e-20
NP_001309925 (OMIM: 604605,608901) kalirin isoform ( 700)  630 101.1 2.7e-20
NP_001309924 (OMIM: 604605,608901) kalirin isoform ( 701)  630 101.1 2.7e-20
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288)  630 101.3 4.3e-20
NP_008995 (OMIM: 604605,608901) kalirin isoform 3  (1289)  630 101.3 4.3e-20
NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613)  608 98.3 4.3e-19
NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641)  608 98.3 4.4e-19
XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643)  608 98.3 4.4e-19
NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650)  608 98.3 4.4e-19
XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652)  608 98.3 4.4e-19
NP_001309918 (OMIM: 604605,608901) kalirin isoform (1654)  608 98.3 4.4e-19
XP_016862922 (OMIM: 604605,608901) PREDICTED: kali (1656)  608 98.3 4.4e-19
NP_003938 (OMIM: 604605,608901) kalirin isoform 2  (1663)  608 98.3 4.4e-19
XP_006713878 (OMIM: 604605,608901) PREDICTED: kali (1665)  608 98.3 4.5e-19
XP_016862921 (OMIM: 604605,608901) PREDICTED: kali (2366)  601 97.4 1.2e-18
XP_011511587 (OMIM: 604605,608901) PREDICTED: kali (2367)  601 97.4 1.2e-18
NP_001309917 (OMIM: 604605,608901) kalirin isoform (2396)  601 97.4 1.2e-18
XP_016862920 (OMIM: 604605,608901) PREDICTED: kali (2398)  601 97.4 1.2e-18
XP_011511585 (OMIM: 604605,608901) PREDICTED: kali (2401)  601 97.4 1.2e-18
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955)  601 97.5 1.4e-18
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956)  601 97.5 1.4e-18


>>XP_011521290 (OMIM: 609526) PREDICTED: puratrophin-1 i  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>XP_011521287 (OMIM: 609526) PREDICTED: puratrophin-1 i  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>XP_011521288 (OMIM: 609526) PREDICTED: puratrophin-1 i  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>NP_001123201 (OMIM: 609526) puratrophin-1 isoform 1 [H  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>NP_001123199 (OMIM: 609526) puratrophin-1 isoform 1 [H  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>NP_001123200 (OMIM: 609526) puratrophin-1 isoform 1 [H  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>XP_011521289 (OMIM: 609526) PREDICTED: puratrophin-1 i  (1191 aa)
 initn: 8084 init1: 8084 opt: 8084  Z-score: 6110.2  bits: 1142.6 E(85289):    0
Smith-Waterman score: 8084; 100.0% identity (100.0% similar) in 1191 aa overlap (1-1191:1-1191)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
             1150      1160      1170      1180      1190 

>>NP_001123203 (OMIM: 609526) puratrophin-1 isoform 2 [H  (1110 aa)
 initn: 6716 init1: 6716 opt: 6740  Z-score: 5095.8  bits: 954.8 E(85289):    0
Smith-Waterman score: 7355; 93.2% identity (93.2% similar) in 1191 aa overlap (1-1191:1-1110)

               10        20        30        40        50        60
pF1KF0 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERPLENGDESPDSQGHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPAGATQDEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KF0 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
NP_001 LQGSPLSRKFQLPPAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQG--
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KF0 DTPGVGLVGDPGPSRAMPSGLSPGALDSDPVGLGDPLSEISKLLEAAPSGSGLPKPADCL
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KF0 LAQDLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
                          :::::::::::::::::::::::::::::::::::::::::
NP_001 -------------------TRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLLYLRSIPR
                         120       130       140       150         

              250       260       270       280       290       300
pF1KF0 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVQALGLTVLVDARICAPSSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEVPSGLQLEQ
     160       170       180       190       200       210         

              310       320       330       340       350       360
pF1KF0 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPSQSLLTHIPTAGLPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAACALLQGAIESVKA
     220       230       240       250       260       270         

              370       380       390       400       410       420
pF1KF0 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEVPEVTLSPDYRTA
     280       290       300       310       320       330         

              430       440       450       460       470       480
pF1KF0 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVWLQQVGWPALEEA
     340       350       360       370       380       390         

              490       500       510       520       530       540
pF1KF0 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPSLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDPPGARFLALRAQLTE
     400       410       420       430       440       450         

              550       560       570       580       590       600
pF1KF0 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPGVVLQQLQLHWTRHPD
     460       470       480       490       500       510         

              610       620       630       640       650       660
pF1KF0 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKLEASLKLPPVGSTASLCV
     520       530       540       550       560       570         

              670       680       690       700       710       720
pF1KF0 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQVPAAPAHPPLRKAYSFDRNLGQSLSEPACHCHHAATIAACRRPEAGGGALPQASPTVP
     580       590       600       610       620       630         

              730       740       750       760       770       780
pF1KF0 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGSSDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFG
     640       650       660       670       680       690         

              790       800       810       820       830       840
pF1KF0 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKLRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGH
     700       710       720       730       740       750         

              850       860       870       880       890       900
pF1KF0 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGPTQELSALREAQSLVHF
     760       770       780       790       800       810         

              910       920       930       940       950       960
pF1KF0 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRH
     820       830       840       850       860       870         

              970       980       990      1000      1010      1020
pF1KF0 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPTGVDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTA
     880       890       900       910       920       930         

             1030      1040      1050      1060      1070      1080
pF1KF0 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRAS
     940       950       960       970       980       990         

             1090      1100      1110      1120      1130      1140
pF1KF0 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVAPFDHDSLYLGASNSLPGDPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
    1000      1010      1020      1030      1040      1050         

             1150      1160      1170      1180      1190 
pF1KF0 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV
    1060      1070      1080      1090      1100      1110

>>XP_016876923 (OMIM: 610018) PREDICTED: rho guanine nuc  (1331 aa)
 initn: 1054 init1: 627 opt: 1180  Z-score: 896.7  bits: 178.1 E(85289): 3.3e-43
Smith-Waterman score: 1461; 31.8% identity (56.6% similar) in 1218 aa overlap (46-1187:177-1326)

          20        30        40        50         60         70   
pF1KF0 GHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPA-GATQDEELQG-SPLSRKFQLP
                                     :: ::  . :  . ..  : . :::  .  
XP_016 EAVGEASGSCPLRPGELRGGGGGGQGAEGPPGTPRRTGKGNRRKKRAAGRGALSRGGDSA
        150       160       170       180       190       200      

            80        90       100       110         120       130 
pF1KF0 PAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQG--ESDTPGVGLVGDP
       : .   :: . ..   . .:.. :.::  .   : . ..   ..:  ::.   .  .:. 
XP_016 PLSP--GDKEDAS--HQEALGNLPSPSEHKLPECHLVKEEYEGSGKPESEPKELKTAGEK
        210           220       230       240       250       260  

             140        150                  160        170        
pF1KF0 GPSRAMPSGLSP-GALDSDPVGLG-----------DPLSEI-SKLLEAAPSGSGLPKPAD
        :. .   : .  :: . .  : :            :::.  .  ::..  :.:   : .
XP_016 EPQLSEACGPTEEGAGERELEGPGLLCMAGHTGPEGPLSDTPTPPLETVQEGKGDNIPEE
            270       280       290       300       310       320  

      180            190       200       210       220       230   
pF1KF0 CLLAQ-----DLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLL
        : ..     :. :.:.:::.  : :  : .:::.: .    :   .   : . :   : 
XP_016 ALAVSVSDHPDVAWDLMASGFLILTGGVDQSGRALLTITPPCPPE-EPPPSRDTLNTTLH
            330       340       350       360        370       380 

           240       250        260       270       280       290  
pF1KF0 YLRSIPRPEVQALGLTVLVDARICAP-SSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEV
       ::.:. ::..:.:::.::.: :   :   .:. .:::::...   . : ::.   .  ..
XP_016 YLHSLLRPDLQTLGLSVLLDLRQAPPLPPALIPALSQLQDSGDPPLVQRLLI--LIHDDL
             390       400       410       420       430           

               300       310        320       330       340        
pF1KF0 PS---GLQLEQLPSQSLLTHIPTAG-LPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAAC
       :.   :.:  .. :.. : ..     :   :::      . :.......  : . ::.. 
XP_016 PTELCGFQGAEVLSENDLKRVAKPEELQWELGGHRDPSPSHWVEIHQEVVRLCRLCQGVL
     440       450       460       470       480       490         

      350       360       370       380       390       400        
pF1KF0 ALLQGAIESVKAVPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEV
       . .. ::: .... .: :   ::  . .    .:.:: .: :. :: .::  :  :..  
XP_016 GSVRQAIEELEGAAEPEEEEAVG--MPKP---LQKVLADPRLTALQRDGGAILMRLRS--
     500       510       520            530       540       550    

      410       420       430       440       450       460        
pF1KF0 PEVTLSPDYRTAMDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVW
            .:. .   .    ::..::  .:::.  :: ..:  :  : :.     :.:.  :
XP_016 -----TPSSKLEGQGPATLYQEVDEAIHQLVRLSNLHVQQQEQRQCLRR----LQQVLQW
                 560       570       580       590           600   

      470       480         490       500       510       520      
pF1KF0 LQQVGWPALEEAGEP--SLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDP
       :.  :   :   . :  .:. : ...  :. .   .::.. :... :       : : . 
XP_016 LSGPGEEQLASFAMPGDTLSALQETELRFRAFSAEVQERLAQAREAL-------ALEENA
           610       620       630       640       650             

        530       540       550       560       570       580      
pF1KF0 PGARFLALRAQLTEFSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPG-
        . . : .      : . : :  . :  : :: ..:..:  :..::   .:.:    :: 
XP_016 TSQKVLDI------FEQRLEQVESGLHRALRLQRFFQQAHEWVDEG---FARLAGAGPGR
        660             670       680       690          700       

          590       600       610       620       630       640    
pF1KF0 -VVLQQLQLHWTRHPDLPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKL-
        .::  : :.  : :.   . :..: :::  ::: :  .:     ::::.    ..:.. 
XP_016 EAVLAALALR--RAPEPSAGTFQEMRALALDLGSPAALREWGRCQARCQELERRIQQHVG
       710         720       730       740       750       760     

                             650         660          670       680
pF1KF0 -EASLKL-----------------P--PVGSTASLCVSQVPA---APAHPPLRKAYSFDR
        ::: .                  :  :  : .:: . . :.   ::.:  :       .
XP_016 EEASPRGYRRRRADGASSGGAQWGPRSPSPSLSSLLLPSSPGPRPAPSHCSLAPCGEDYE
         770       780       790       800       810       820     

              690       700                       710       720    
pF1KF0 NLGQSLSEPACHCHHAATIA-------------ACRRPEA---GGGALPQASPTVPPPGS
       . :  :.  :      :..              .:   :    : .  :..   :  :  
XP_016 EEGPELAPEAEGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRARGPDGPWGVGTPRM
         830       840       850       860       870       880     

          730       740       750       760       770       780    
pF1KF0 SDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFGNLEK
          ::..  : ...:..: :..:: .:   .    :::    .:. :::  :  ..  :.
XP_016 ERKRSISAQQRLVSELIACEQDYVATLSEPVPPPGPEL----TPE-LRGTWAAALSARER
         890       900       910       920            930       940

          790       800       810       820       830       840    
pF1KF0 LRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGHTFFK
       ::.::   :::::..:. :: :..  ::::  ::..:: : :.. . .  ... .  . :
XP_016 LRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALS-PLSK
              950       960       970       980       990          

          850       860       870       880         890       900  
pF1KF0 DKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGP--TQELSALREAQSLVHFQL
        ...: : .:  :  : .:.... .:. ::.:: :  .::  ..:  ::  : .:.. : 
XP_016 GSMEA-GPYLPRA--LQQPLEQLTRYGRLLEELLRE-AGPELSSECRALGAAVQLLREQE
    1000       1010        1020      1030       1040      1050     

            910       920       930       940       950       960  
pF1KF0 RHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRHGP
        .: ::::..:..::...:::::::...: :.:  ::.: .:..::::.:::::: . ::
XP_016 ARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEHLLLFSKLK-GP
        1060      1070      1080      1090      1100      1110     

             970       980       990      1000      1010      1020 
pF1KF0 TG-VDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTAD
        :  . :.::..:: ::.::::  :.:.: ::.:::::.::....:::.:  ::  ::..
XP_016 EGGSEMFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLKWTSS
         1120      1130      1140      1150      1160      1170    

            1030      1040      1050      1060      1070      1080 
pF1KF0 ISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRASI
       :..::::::.::::.:. .:::::.::: : ::    .:...::.. .:  : .:.:::.
XP_016 IAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDI----KALGERTLSALLTGRAARTRASV
         1180      1190      1200          1210      1220      1230

            1090      1100       1110       1120      1130         
pF1KF0 AVAPFDHDSLYLGASNSLPG-DPASCSVLGSLNLHLYR-DPALLGLRCPLYPSFPEEAAL
       ::. :.:      :. :::: .:..::. . .. . .  :   ..:  :   : ::    
XP_016 AVSSFEH------AGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASP---SAPETLDS
                   1240      1250      1260      1270         1280 

    1140      1150      1160      1170      1180      1190  
pF1KF0 EAEAELGGQPSLTAEDSEISSQCPSASGSSGSDSSCVSGQALGRGLEDLPCV 
        ...  : . : . .  . .:. :. . : :  .  .: :. .:.: :     
XP_016 SGDVSPGPRNSPSLQPPHPGSSTPTLA-SRGILG--LSRQSHARALSDPTTPL
            1290      1300       1310        1320      1330 

>>NP_060541 (OMIM: 610018) rho guanine nucleotide exchan  (1519 aa)
 initn: 1054 init1: 627 opt: 1180  Z-score: 895.9  bits: 178.1 E(85289): 3.6e-43
Smith-Waterman score: 1452; 32.5% identity (57.0% similar) in 1138 aa overlap (46-1108:369-1444)

          20        30        40        50         60         70   
pF1KF0 GHATDWRFAVCSFRDAWEEEEPASQMHVKDPGPPRPPA-GATQDEELQG-SPLSRKFQLP
                                     :: ::  . :  . ..  : . :::  .  
NP_060 EAVGEASGSCPLRPGELRGGGGGGQGAEGPPGTPRRTGKGNRRKKRAAGRGALSRGGDSA
      340       350       360       370       380       390        

            80        90       100       110         120       130 
pF1KF0 PAADESGDAQRGTVESSSVLSEGPGPSGVESLLCPMSSHLSLAQG--ESDTPGVGLVGDP
       : .   :: . .. . .  :.. :.::  .   : . ..   ..:  ::.   .  .:. 
NP_060 PLS--PGDKEDASHQEA--LGNLPSPSEHKLPECHLVKEEYEGSGKPESEPKELKTAGEK
      400         410         420       430       440       450    

             140        150                  160        170        
pF1KF0 GPSRAMPSGLSP-GALDSDPVGLG-----------DPLSEI-SKLLEAAPSGSGLPKPAD
        :. .   : .  :: . .  : :            :::.  .  ::..  :.:   : .
NP_060 EPQLSEACGPTEEGAGERELEGPGLLCMAGHTGPEGPLSDTPTPPLETVQEGKGDNIPEE
          460       470       480       490       500       510    

      180            190       200       210       220       230   
pF1KF0 CLLAQ-----DLCWELLASGMATLPGTRDVQGRAVLLLCAHSPAWLQSECSSQELIRLLL
        : ..     :. :.:.:::.  : :  : .:::.: .    :   .   : . :   : 
NP_060 ALAVSVSDHPDVAWDLMASGFLILTGGVDQSGRALLTITPPCPPE-EPPPSRDTLNTTLH
          520       530       540       550        560       570   

           240       250        260       270       280       290  
pF1KF0 YLRSIPRPEVQALGLTVLVDARICAP-SSSLFSGLSQLQEAAPGAVYQVLLVGSTLLKEV
       ::.:. ::..:.:::.::.: :   :   .:. .:::::...   . : ::.   .  ..
NP_060 YLHSLLRPDLQTLGLSVLLDLRQAPPLPPALIPALSQLQDSGDPPLVQRLLI--LIHDDL
           580       590       600       610       620         630 

               300       310        320       330       340        
pF1KF0 PS---GLQLEQLPSQSLLTHIPTAG-LPTSLGGGLPYCHQAWLDFRRRLEALLQNCQAAC
       :.   :.:  .. :.. : ..     :   :::      . :.......  : . ::.. 
NP_060 PTELCGFQGAEVLSENDLKRVAKPEELQWELGGHRDPSPSHWVEIHQEVVRLCRLCQGVL
             640       650       660       670       680       690 

      350       360       370       380       390       400        
pF1KF0 ALLQGAIESVKAVPQPMEPGEVGQLLQQTEVLMQQVLDSPWLAWLQCQGGRELTWLKQEV
       . .. ::: .... .: :   ::  . .    .:.:: .: :. :: .::  :  :..  
NP_060 GSVRQAIEELEGAAEPEEEEAVG--MPKP---LQKVLADPRLTALQRDGGAILMRLRS--
             700       710            720       730       740      

      410       420       430       440       450       460        
pF1KF0 PEVTLSPDYRTAMDKADELYDRVDGLLHQLTLQSNQRIQALELVQTLEARESGLHQIEVW
            .:. .   .    ::..::  .:::.  :: ..:  :  : :.     :.:.  :
NP_060 -----TPSSKLEGQGPATLYQEVDEAIHQLVRLSNLHVQQQEQRQCLRR----LQQVLQW
               750       760       770       780           790     

      470       480         490       500       510       520      
pF1KF0 LQQVGWPALEEAGEP--SLDMLLQAQGSFQELYQVAQEQVRQGEKFLQPLTGWEAAELDP
       :.  :   :   . :  .:. : ...  :. .   .::.. :... :       : : . 
NP_060 LSGPGEEQLASFAMPGDTLSALQETELRFRAFSAEVQERLAQAREAL-------ALEENA
         800       810       820       830       840               

        530       540       550       560       570       580      
pF1KF0 PGARFLALRAQLTEFSRALAQRCQRLADAERLFQLFREALTWAEEGQRVLAELEQERPG-
        . . : .      : . : :  . :  : :: ..:..:  :..::   .:.:    :: 
NP_060 TSQKVLDI------FEQRLEQVESGLHRALRLQRFFQQAHEWVDEG---FARLAGAGPGR
      850             860       870       880          890         

          590       600       610       620       630       640    
pF1KF0 -VVLQQLQLHWTRHPDLPPAHFRKMWALATGLGSEAIRQECRWAWARCQDTWLALDQKL-
        .::  : :.  : :.   . :..: :::  ::: :  .:     ::::.    ..:.. 
NP_060 EAVLAALALR--RAPEPSAGTFQEMRALALDLGSPAALREWGRCQARCQELERRIQQHVG
     900         910       920       930       940       950       

                             650         660          670       680
pF1KF0 -EASLKL-----------------P--PVGSTASLCVSQVPA---APAHPPLRKAYSFDR
        ::: .                  :  :  : .:: . . :.   ::.:  :       .
NP_060 EEASPRGYRRRRADGASSGGAQWGPRSPSPSLSSLLLPSSPGPRPAPSHCSLAPCGEDYE
       960       970       980       990      1000      1010       

              690       700                       710       720    
pF1KF0 NLGQSLSEPACHCHHAATIA-------------ACRRPEA---GGGALPQASPTVPPPGS
       . :  :.  :      :..              .:   :    : .  :..   :  :  
NP_060 EEGPELAPEAEGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRARGPDGPWGVGTPRM
      1020      1030      1040      1050      1060      1070       

          730       740       750       760       770       780    
pF1KF0 SDPRSLNRLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAHLFGNLEK
          ::..  : ...:..: :..:: .:   .    :::    .:. :::  :  ..  :.
NP_060 ERKRSISAQQRLVSELIACEQDYVATLSEPVPPPGPEL----TPE-LRGTWAAALSARER
      1080      1090      1100      1110           1120      1130  

          790       800       810       820       830       840    
pF1KF0 LRDFHCHFFLRELEACTRHPPRVAYAFLRHRVQFGMYALYSKNKPRSDALMSSYGHTFFK
       ::.::   :::::..:. :: :..  ::::  ::..:: : :.. . .  ... .  . :
NP_060 LRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALS-PLSK
           1140      1150      1160      1170      1180       1190 

          850       860       870       880         890       900  
pF1KF0 DKQQALGDHLDLASYLLKPIQRMGKYALLLQELARACGGP--TQELSALREAQSLVHFQL
        ...: : .:  :  : .:.... .:. ::.:: :  .::  ..:  ::  : .:.. : 
NP_060 GSMEA-GPYLPRA--LQQPLEQLTRYGRLLEELLRE-AGPELSSECRALGAAVQLLREQE
             1200        1210      1220       1230      1240       

            910       920       930       940       950       960  
pF1KF0 RHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFVVRTGRHKSVRRIFLFEELLLFSKPRHGP
        .: ::::..:..::...:::::::...: :.:  ::.: .:..::::.:::::: . ::
NP_060 ARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEHLLLFSKLK-GP
      1250      1260      1270      1280      1290      1300       

             970       980       990      1000      1010      1020 
pF1KF0 TG-VDTFAYKRSFKMADLGLTECCGNSNLRFEIWFRRRKARDTFVLQASSLAIKQAWTAD
        :  . :.::..:: ::.::::  :.:.: ::.:::::.::....:::.:  ::  ::..
NP_060 EGGSEMFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQATSPEIKLKWTSS
       1310      1320      1330      1340      1350      1360      

            1030      1040      1050      1060      1070      1080 
pF1KF0 ISHLLWRQAVHNKEVRMAEMVSMGVGNKAFRDIAPSEEAINDRTVNYVLKCREVRSRASI
       :..::::::.::::.:. .:::::.::: : ::    .:...::.. .:  : .:.:::.
NP_060 IAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDI----KALGERTLSALLTGRAARTRASV
       1370      1380      1390          1400      1410      1420  

            1090      1100       1110      1120      1130      1140
pF1KF0 AVAPFDHDSLYLGASNSLPG-DPASCSVLGSLNLHLYRDPALLGLRCPLYPSFPEEAALE
       ::. :.:      :. :::: .:..::.                                
NP_060 AVSSFEH------AGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPG
                 1430      1440      1450      1460      1470      




1191 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:06:23 2016 done: Fri Nov  4 20:06:25 2016
 Total Scan time: 17.660 Total Display time:  0.570

Function used was FASTA [36.3.4 Apr, 2011]
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