Result of FASTA (omim) for pF1KB9770
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9770, 462 aa
  1>>>pF1KB9770 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2421+/-0.000412; mu= -0.0399+/- 0.026
 mean_var=215.8311+/-44.547, 0's: 0 Z-trim(118.6): 403  B-trim: 1730 in 1/55
 Lambda= 0.087301
 statistics sampled from 31238 (31648) to 31238 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.371), width:  16
 Scan time:  8.980

The best scores are:                                      opt bits E(85289)
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 3123 406.2 9.8e-113
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 2946 383.9 4.8e-106
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 2464 323.1 7.9e-88
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 2162 285.1 2.7e-76
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 2137 282.0 2.7e-75
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 2119 279.8 1.3e-74
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 2076 274.3 4.5e-73
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 1998 264.5 4.3e-70
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 1983 262.5 1.3e-69
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 1983 262.5 1.3e-69
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 1933 256.2   1e-67
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 1933 256.3 1.2e-67
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 1001 138.9 2.6e-32
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423)  972 135.2 3.3e-31
XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte  ( 408)  916 128.2 4.2e-29
NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408)  916 128.2 4.2e-29
XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte  ( 408)  916 128.2 4.2e-29
XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte  ( 408)  916 128.2 4.2e-29
XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte  ( 408)  916 128.2 4.2e-29
NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445)  916 128.2 4.5e-29
NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439)  907 127.1 9.8e-29
NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442)  907 127.1 9.9e-29
NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449)  907 127.1   1e-28
NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452)  907 127.1   1e-28
NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464)  907 127.1   1e-28
NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467)  907 127.1   1e-28
NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474)  907 127.1   1e-28
XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513)  907 127.1 1.1e-28
NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392)  902 126.4 1.4e-28
NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395)  902 126.4 1.4e-28
NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417)  902 126.4 1.5e-28
XP_016856128 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
NP_001230440 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
XP_016856129 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
XP_016856138 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
XP_016856134 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
NP_001127757 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
NP_001230442 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
XP_016856133 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
NP_001230443 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
XP_016856135 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
NP_001230439 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22
NP_001230441 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
NP_001230448 (OMIM: 602969) estrogen-related recep ( 435)  743 106.4 1.6e-22
NP_996318 (OMIM: 602969) estrogen-related receptor ( 435)  743 106.4 1.6e-22
XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  743 106.4 1.6e-22


>>NP_002948 (OMIM: 180245) retinoic acid receptor RXR-al  (462 aa)
 initn: 3123 init1: 3123 opt: 3123  Z-score: 2144.9  bits: 406.2 E(85289): 9.8e-113
Smith-Waterman score: 3123; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)

               10        20        30        40        50        60
pF1KB9 MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
              370       380       390       400       410       420

              430       440       450       460  
pF1KB9 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
       ::::::::::::::::::::::::::::::::::::::::::
NP_002 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
              430       440       450       460  

>>NP_001278849 (OMIM: 180245) retinoic acid receptor RXR  (435 aa)
 initn: 2946 init1: 2946 opt: 2946  Z-score: 2024.8  bits: 383.9 E(85289): 4.8e-106
Smith-Waterman score: 2946; 100.0% identity (100.0% similar) in 435 aa overlap (28-462:1-435)

               10        20        30        40        50        60
pF1KB9 MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
                                  :::::::::::::::::::::::::::::::::
NP_001                            MAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
                                          10        20        30   

               70        80        90       100       110       120
pF1KB9 MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
            40        50        60        70        80        90   

              130       140       150       160       170       180
pF1KB9 AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
           100       110       120       130       140       150   

              190       200       210       220       230       240
pF1KB9 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
           160       170       180       190       200       210   

              250       260       270       280       290       300
pF1KB9 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
           220       230       240       250       260       270   

              310       320       330       340       350       360
pF1KB9 LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
           280       290       300       310       320       330   

              370       380       390       400       410       420
pF1KB9 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
           340       350       360       370       380       390   

              430       440       450       460  
pF1KB9 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
           400       410       420       430     

>>NP_001278850 (OMIM: 180245) retinoic acid receptor RXR  (365 aa)
 initn: 2464 init1: 2464 opt: 2464  Z-score: 1697.8  bits: 323.1 E(85289): 7.9e-88
Smith-Waterman score: 2464; 100.0% identity (100.0% similar) in 365 aa overlap (98-462:1-365)

        70        80        90       100       110       120       
pF1KB9 ISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNM
                                     ::::::::::::::::::::::::::::::
NP_001                               MNPVSSSEDIKPPLGLNGVLKVPAHPSGNM
                                             10        20        30

       130       140       150       160       170       180       
pF1KB9 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRC
               40        50        60        70        80        90

       190       200       210       220       230       240       
pF1KB9 QYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTE
              100       110       120       130       140       150

       250       260       270       280       290       300       
pF1KB9 TYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNE
              160       170       180       190       200       210

       310       320       330       340       350       360       
pF1KB9 LLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTEL
              220       230       240       250       260       270

       370       380       390       400       410       420       
pF1KB9 GCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRS
              280       290       300       310       320       330

       430       440       450       460  
pF1KB9 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
       :::::::::::::::::::::::::::::::::::
NP_001 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
              340       350       360     

>>NP_008848 (OMIM: 180247) retinoic acid receptor RXR-ga  (463 aa)
 initn: 2139 init1: 1217 opt: 2162  Z-score: 1490.8  bits: 285.1 E(85289): 2.7e-76
Smith-Waterman score: 2162; 73.8% identity (87.1% similar) in 451 aa overlap (21-462:18-463)

               10        20         30        40         50        
pF1KB9 MDTKHFLPLDFSTQVNSSLTSPTGRGSMA-APSLHPSLGPGIGS-PGQLHSPIS---TLS
                           ::   :: . .::   : :  . : :.   .:.:   :::
NP_008    MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLS
                  10        20        30        40        50       

             60        70        80         90       100       110 
pF1KB9 ---SPINGMGPPFSVISSPMGPHSMSVPTTPTLGF-STGSPQLSSPMNPVSSSEDIKPPL
          .:.:..: :. ::.: ::: : .. . : ... .  : ::.  .: :::::::::  
NP_008 AVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNV-VNSVSSSEDIKPLP
        60        70        80        90       100        110      

             120       130       140       150       160       170 
pF1KB9 GLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTC
       :: :. ..  .:: . .:..:::::::::::::::::::::::::::::::.:::: :::
NP_008 GLPGIGNM-NYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTC
        120        130       140       150       160       170     

             180       190       200       210       220       230 
pF1KB9 RDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMP
       :::::::::::::::::::::::::.::::::::::::::...: :.:.: ..:..::::
NP_008 RDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMP
         180       190       200       210       220       230     

             240       250       260       270       280       290 
pF1KB9 VERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSE
       ::::::::::::::::.: . ::    .: ::::::::.::::::::::::::::::::.
NP_008 VERILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSD
         240       250          260       270       280       290  

             300       310       320       330       340       350 
pF1KB9 LPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLT
       : :.::::::::::::::::::::::..:.:::::::::::::.::::::::.:::::::
NP_008 LTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLT
            300       310       320       330       340       350  

             360       370       380       390       400       410 
pF1KB9 ELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQ
       ::::::.::::::.::::::::::::::.::::::.:::.:::::::.:::: :.:::::
NP_008 ELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQ
            360       370       380       390       400       410  

             420       430       440       450       460  
pF1KB9 PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
       :::::::::::::::::::::::::::::::::::::::::::::.: :.:
NP_008 PGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQIT
            420       430       440       450       460   

>>NP_068811 (OMIM: 180246) retinoic acid receptor RXR-be  (533 aa)
 initn: 2092 init1: 1281 opt: 2137  Z-score: 1472.9  bits: 282.0 E(85289): 2.7e-75
Smith-Waterman score: 2137; 72.0% identity (84.6% similar) in 461 aa overlap (12-461:80-532)

                                  10        20            30       
pF1KB9                    MDTKHFLPLDFSTQVNSSLTSPTGRG----SMAAPSLHPSL
                                     : . .::  .:  .:    :  .: : :: 
NP_068 AAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPST
      50        60        70        80        90       100         

        40        50        60        70        80        90       
pF1KB9 GPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSP
       .:..:. :    :   .  :   .: :: :::: ::  ..  :. : ..  ..:::..: 
NP_068 APSLGGSGA--PPPPPMPPP--PLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINST
     110         120         130       140       150       160     

        100          110        120       130       140       150  
pF1KB9 MN-PVSSS---EDIKPP-LGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSC
       .. : ..:   ::.::: ::. : :. :  :.:  :.  :..::::::::::::::::::
NP_068 VSLPGGGSGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KRLCAICGDRSSGKHYGVYSC
         170       180        190       200         210       220  

            160       170       180       190       200       210  
pF1KB9 EGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG
       ::::::::::.::::::.::::::: .:::::::::::::::::: ::::::::::::::
NP_068 EGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRG
            230       240       250       260       270       280  

            220       230       240       250         260       270
pF1KB9 KDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA--NMGLNPSSPNDPVTNICQ
       ::.. .. :....: :.:::.:::::::::: :..  ::.  . : . ::::::::::::
NP_068 KDKD-GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQ
             290       300       310       320       330       340 

              280       290       300       310       320       330
pF1KB9 AADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGL
       :::::::::::::::::::: ::::::::::::::::::::::::::: :.:::::::::
NP_068 AADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGL
             350       360       370       380       390       400 

              340       350       360       370       380       390
pF1KB9 HVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVE
       ::::::::::::::::::::::::::::::.::::::::::::.:::::.::::::.:::
NP_068 HVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVE
             410       420       430       440       450       460 

              400       410       420       430       440       450
pF1KB9 ALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF
       .::::::::::.:::.::::: ::::::::::::::::::::::::::::::::::::::
NP_068 VLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF
             470       480       490       500       510       520 

              460  
pF1KB9 LMEMLEAPHQMT
       ::::::::::. 
NP_068 LMEMLEAPHQLA
             530   

>>NP_001257330 (OMIM: 180246) retinoic acid receptor RXR  (537 aa)
 initn: 2099 init1: 707 opt: 2119  Z-score: 1460.6  bits: 279.8 E(85289): 1.3e-74
Smith-Waterman score: 2119; 71.4% identity (83.9% similar) in 465 aa overlap (12-461:80-536)

                                  10        20            30       
pF1KB9                    MDTKHFLPLDFSTQVNSSLTSPTGRG----SMAAPSLHPSL
                                     : . .::  .:  .:    :  .: : :: 
NP_001 AAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPST
      50        60        70        80        90       100         

        40        50        60        70        80        90       
pF1KB9 GPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSP
       .:..:. :    :   .  :   .: :: :::: ::  ..  :. : ..  ..:::..: 
NP_001 APSLGGSGA--PPPPPMPPP--PLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINST
     110         120         130       140       150       160     

        100          110        120       130       140       150  
pF1KB9 MN-PVSSS---EDIKPP-LGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSC
       .. : ..:   ::.::: ::. : :. :  :.:  :.  :..::::::::::::::::::
NP_001 VSLPGGGSGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KRLCAICGDRSSGKHYGVYSC
         170       180        190       200         210       220  

            160       170       180       190       200       210  
pF1KB9 EGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG
       ::::::::::.::::::.::::::: .:::::::::::::::::: ::::::::::::::
NP_001 EGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRG
            230       240       250       260       270       280  

            220       230       240       250         260       270
pF1KB9 KDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA--NMGLNPSSPNDPVTNICQ
       ::.. .. :....: :.:::.:::::::::: :..  ::.  . : . ::::::::::::
NP_001 KDKD-GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQ
             290       300       310       320       330       340 

              280       290       300       310       320       330
pF1KB9 AADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGL
       :::::::::::::::::::: ::::::::::::::::::::::::::: :.:::::::::
NP_001 AADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGL
             350       360       370       380       390       400 

              340           350       360       370       380      
pF1KB9 HVHRNSAHSAGVGAIFDR----VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP
       ::::::::::::::::::    ::::::::::::.::::::::::::.:::::.::::::
NP_001 HVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNP
             410       420       430       440       450       460 

        390       400       410       420       430       440      
pF1KB9 AEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
       .:::.::::::::::.:::.::::: ::::::::::::::::::::::::::::::::::
NP_001 SEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
             470       480       490       500       510       520 

        450       460  
pF1KB9 IDTFLMEMLEAPHQMT
       ::::::::::::::. 
NP_001 IDTFLMEMLEAPHQLA
             530       

>>XP_016866665 (OMIM: 180246) PREDICTED: retinoic acid r  (414 aa)
 initn: 2104 init1: 707 opt: 2076  Z-score: 1432.9  bits: 274.3 E(85289): 4.5e-73
Smith-Waterman score: 2076; 76.4% identity (88.0% similar) in 416 aa overlap (57-461:2-413)

         30        40        50        60        70        80      
pF1KB9 SMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLG
                                     :   .: :: :::: ::  ..  :. : ..
XP_016                              MPPPPLGSPFPVISSSMGSPGLPPPAPPGFS
                                            10        20        30 

         90        100          110        120       130       140 
pF1KB9 FSTGSPQLSSPMN-PVSSS---EDIKPP-LGLNGVLKVPAHPSGNMASFTKHICAICGDR
         ..:::..: .. : ..:   ::.::: ::. : :. :  :.:  :.  :..:::::::
XP_016 GPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KRLCAICGDR
              40        50        60         70          80        

             150       160       170       180       190       200 
pF1KB9 SSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMK
       :::::::::::::::::::::.::::::.::::::: .:::::::::::::::::: :::
XP_016 SSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMK
       90       100       110       120       130       140        

             210       220       230       240       250           
pF1KB9 REAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA--NMGLNPS
       :::::::::::::.. .. :....: :.:::.:::::::::: :..  ::.  . : . :
XP_016 REAVQEERQRGKDKD-GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGS
      150       160        170       180       190       200       

     260       270       280       290       300       310         
pF1KB9 SPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIA
       ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: 
XP_016 SPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSID
       210       220       230       240       250       260       

     320       330       340           350       360       370     
pF1KB9 VKDGILLATGLHVHRNSAHSAGVGAIFDR----VLTELVSKMRDMQMDKTELGCLRAIVL
       :.:::::::::::::::::::::::::::    ::::::::::::.::::::::::::.:
XP_016 VRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIIL
       270       280       290       300       310       320       

         380       390       400       410       420       430     
pF1KB9 FNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEH
       ::::.::::::.:::.::::::::::.:::.::::: :::::::::::::::::::::::
XP_016 FNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEH
       330       340       350       360       370       380       

         440       450       460  
pF1KB9 LFFFKLIGDTPIDTFLMEMLEAPHQMT
       :::::::::::::::::::::::::. 
XP_016 LFFFKLIGDTPIDTFLMEMLEAPHQLA
       390       400       410    

>>XP_005249335 (OMIM: 180246) PREDICTED: retinoic acid r  (441 aa)
 initn: 1989 init1: 707 opt: 1998  Z-score: 1379.4  bits: 264.5 E(85289): 4.3e-70
Smith-Waterman score: 1998; 77.1% identity (87.7% similar) in 398 aa overlap (74-461:47-440)

            50        60        70        80        90          100
pF1KB9 PGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTG---SPQLSSPMNP
                                     :.: :       :..:.   .  .: : . 
XP_005 VGSRPGGGGDGPGWIPQRRRRRRWQAENNKPRSRSQGRLDGTGWATAGGINSTVSLPGGG
         20        30        40        50        60        70      

              110        120       130       140       150         
pF1KB9 VSSSEDIKPP-LGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFF
        .  ::.::: ::. : :. :  :.:  :.  :..:::::::::::::::::::::::::
XP_005 SGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KRLCAICGDRSSGKHYGVYSCEGCKGFF
         80        90        100         110       120       130   

     160       170       180       190       200       210         
pF1KB9 KRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENE
       :::.::::::.::::::: .:::::::::::::::::: ::::::::::::::::.. ..
XP_005 KRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD-GD
           140       150       160       170       180       190   

     220       230       240       250         260       270       
pF1KB9 VESTSSANEDMPVERILEAELAVEPKTETYVEA--NMGLNPSSPNDPVTNICQAADKQLF
        :....: :.:::.:::::::::: :..  ::.  . : . :::::::::::::::::::
XP_005 GEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLF
            200       210       220       230       240       250  

       280       290       300       310       320       330       
pF1KB9 TLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSA
       ::::::::::::: ::::::::::::::::::::::::::: :.::::::::::::::::
XP_005 TLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSA
            260       270       280       290       300       310  

       340           350       360       370       380       390   
pF1KB9 HSAGVGAIFDR----VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALR
       :::::::::::    ::::::::::::.::::::::::::.:::::.::::::.:::.::
XP_005 HSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLR
            320       330       340       350       360       370  

           400       410       420       430       440       450   
pF1KB9 EKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLME
       ::::::::.:::.::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 EKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLME
            380       390       400       410       420       430  

           460  
pF1KB9 MLEAPHQMT
       :::::::. 
XP_005 MLEAPHQLA
            440 

>>NP_001243500 (OMIM: 180247) retinoic acid receptor RXR  (340 aa)
 initn: 1985 init1: 1217 opt: 1983  Z-score: 1370.9  bits: 262.5 E(85289): 1.3e-69
Smith-Waterman score: 1983; 85.0% identity (95.6% similar) in 341 aa overlap (122-462:3-340)

             100       110       120       130       140       150 
pF1KB9 PQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYS
                                     .:: . .:..::::::::::::::::::::
NP_001                             MNYPSTSPGSLVKHICAICGDRSSGKHYGVYS
                                           10        20        30  

             160       170       180       190       200       210 
pF1KB9 CEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQR
       :::::::::::.:::: ::::::::::::::::::::::::::::.::::::::::::::
NP_001 CEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQR
             40        50        60        70        80        90  

             220       230       240       250       260       270 
pF1KB9 GKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQA
       ...: :.:.: ..:..::::::::::::::::::::.: . ::    .: ::::::::.:
NP_001 SRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHA
            100       110       120       130          140         

             280       290       300       310       320       330 
pF1KB9 ADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLH
       :::::::::::::::::::.: :.::::::::::::::::::::::..:.::::::::::
NP_001 ADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLH
     150       160       170       180       190       200         

             340       350       360       370       380       390 
pF1KB9 VHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA
       :::.::::::::.:::::::::::::.::::::.::::::::::::::.::::::.:::.
NP_001 VHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVET
     210       220       230       240       250       260         

             400       410       420       430       440       450 
pF1KB9 LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL
       :::::::.:::: :.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL
     270       280       290       300       310       320         

             460  
pF1KB9 MEMLEAPHQMT
       :::::.: :.:
NP_001 MEMLETPLQIT
     330       340

>>NP_001243499 (OMIM: 180247) retinoic acid receptor RXR  (340 aa)
 initn: 1985 init1: 1217 opt: 1983  Z-score: 1370.9  bits: 262.5 E(85289): 1.3e-69
Smith-Waterman score: 1983; 85.0% identity (95.6% similar) in 341 aa overlap (122-462:3-340)

             100       110       120       130       140       150 
pF1KB9 PQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYS
                                     .:: . .:..::::::::::::::::::::
NP_001                             MNYPSTSPGSLVKHICAICGDRSSGKHYGVYS
                                           10        20        30  

             160       170       180       190       200       210 
pF1KB9 CEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQR
       :::::::::::.:::: ::::::::::::::::::::::::::::.::::::::::::::
NP_001 CEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQR
             40        50        60        70        80        90  

             220       230       240       250       260       270 
pF1KB9 GKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQA
       ...: :.:.: ..:..::::::::::::::::::::.: . ::    .: ::::::::.:
NP_001 SRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNM---ENSTNDPVTNICHA
            100       110       120       130          140         

             280       290       300       310       320       330 
pF1KB9 ADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLH
       :::::::::::::::::::.: :.::::::::::::::::::::::..:.::::::::::
NP_001 ADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLH
     150       160       170       180       190       200         

             340       350       360       370       380       390 
pF1KB9 VHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA
       :::.::::::::.:::::::::::::.::::::.::::::::::::::.::::::.:::.
NP_001 VHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVET
     210       220       230       240       250       260         

             400       410       420       430       440       450 
pF1KB9 LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL
       :::::::.:::: :.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL
     270       280       290       300       310       320         

             460  
pF1KB9 MEMLEAPHQMT
       :::::.: :.:
NP_001 MEMLETPLQIT
     330       340




462 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:47:55 2016 done: Fri Nov  4 18:47:56 2016
 Total Scan time:  8.980 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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