Result of FASTA (omim) for pF1KB9720
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9720, 404 aa
  1>>>pF1KB9720 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1042+/-0.000301; mu= 15.4306+/- 0.019
 mean_var=109.3161+/-21.957, 0's: 0 Z-trim(120.5): 410  B-trim: 0 in 0/52
 Lambda= 0.122668
 statistics sampled from 35354 (35770) to 35354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.419), width:  16
 Scan time: 10.140

The best scores are:                                      opt bits E(85289)
NP_005225 (OMIM: 132880) nuclear receptor subfamil ( 404) 2748 496.5 4.8e-140
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 1243 230.2 7.4e-60
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 1200 222.6 1.4e-57
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 1164 216.0 8.7e-56
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 1162 215.7 1.1e-55
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 1162 215.7 1.1e-55
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 1162 215.7 1.1e-55
XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508)  667 128.3 4.1e-29
NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508)  667 128.3 4.1e-29
XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529)  667 128.3 4.3e-29
XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531)  667 128.3 4.3e-29
XP_011534852 (OMIM: 602167,608565) PREDICTED: ster ( 552)  667 128.3 4.4e-29
XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552)  667 128.3 4.4e-29
XP_011534849 (OMIM: 602167,608565) PREDICTED: ster ( 573)  667 128.4 4.5e-29
NP_001269379 (OMIM: 601998) steroid hormone recept ( 423)  653 125.8   2e-28
NP_004442 (OMIM: 601998) steroid hormone receptor  ( 423)  653 125.8   2e-28
XP_016872802 (OMIM: 601998) PREDICTED: steroid hor ( 433)  653 125.8   2e-28
NP_001269380 (OMIM: 601998) steroid hormone recept ( 422)  648 124.9 3.7e-28
NP_055064 (OMIM: 268100,604485,611131) photorecept ( 410)  633 122.2 2.3e-27
XP_016856123 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856126 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507578 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856122 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507582 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507581 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507577 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856124 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507579 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856120 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856121 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_016856125 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507576 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507580 (OMIM: 602969) PREDICTED: estrogen-re ( 442)  627 121.2   5e-27
XP_011507573 (OMIM: 602969) PREDICTED: estrogen-re ( 447)  627 121.2 5.1e-27
XP_016856119 (OMIM: 602969) PREDICTED: estrogen-re ( 447)  627 121.2 5.1e-27
XP_016856118 (OMIM: 602969) PREDICTED: estrogen-re ( 447)  627 121.2 5.1e-27
XP_016856117 (OMIM: 602969) PREDICTED: estrogen-re ( 461)  627 121.2 5.2e-27
XP_011507572 (OMIM: 602969) PREDICTED: estrogen-re ( 465)  627 121.2 5.2e-27
XP_011507570 (OMIM: 602969) PREDICTED: estrogen-re ( 470)  627 121.2 5.3e-27
XP_011507569 (OMIM: 602969) PREDICTED: estrogen-re ( 470)  627 121.2 5.3e-27
NP_001230447 (OMIM: 602969) estrogen-related recep ( 470)  627 121.2 5.3e-27
XP_011507571 (OMIM: 602969) PREDICTED: estrogen-re ( 470)  627 121.2 5.3e-27
XP_016856110 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_016856112 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_016856113 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_011507567 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_016856114 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_016856111 (OMIM: 602969) PREDICTED: estrogen-re ( 477)  627 121.2 5.3e-27
XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  624 120.6 7.2e-27
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435)  624 120.6 7.2e-27


>>NP_005225 (OMIM: 132880) nuclear receptor subfamily 2   (404 aa)
 initn: 2748 init1: 2748 opt: 2748  Z-score: 2635.3  bits: 496.5 E(85289): 4.8e-140
Smith-Waterman score: 2748; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)

               10        20        30        40        50        60
pF1KB9 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL
              310       320       330       340       350       360

              370       380       390       400    
pF1KB9 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
       ::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
              370       380       390       400    

>>NP_005645 (OMIM: 132890,615722) COUP transcription fac  (423 aa)
 initn: 1660 init1: 1089 opt: 1243  Z-score: 1195.6  bits: 230.2 E(85289): 7.4e-60
Smith-Waterman score: 1713; 64.3% identity (82.0% similar) in 406 aa overlap (9-404:32-421)

                                     10        20         30       
pF1KB9                       MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
                                     :: ::  .  ..:: : :.. .  . . ::
NP_005 AMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQ--TPGQPG
              10        20        30        40        50           

         40          50             60        70        80         
pF1KB9 A-ASDAEPGDEER--PG-----LQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLS
       : :. .  ::. .  ::      ...:::::::::::::: :::::::::::::.::::.
NP_005 APATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLT
      60        70        80        90       100       110         

      90       100       110       120       130       140         
pF1KB9 YTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGS
       ::::.::.: :::::::::::::::::..::::.:::::::.: . :        .:   
NP_005 YTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQP--------NPGQY
     120       130       140       150       160               170 

     150       160        170       180       190       200        
pF1KB9 ALAAVASGGDLFPGQ-PVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAAR
       ::    ..:: . :.  .:  :. ::::::::..  :.:.     . ..::.:.::::::
NP_005 AL----TNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAAR
                 180       190       200         210       220     

      210       220       230       240       250       260        
pF1KB9 LLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAA
       ::::.:::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.
NP_005 LLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHAS
         230       240       250       260       270       280     

      270       280       290       300       310       320        
pF1KB9 PMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQ
       ::.:.:.:::::..: :::::.::  :.::::::.:::::.::: ::::::: ::.::::
NP_005 PMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQ
         290       300       310       320       330       340     

      330       340       350       360       370       380        
pF1KB9 EKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRD
       ::.: :: ::::.:::.::.:::.::::::.::.: .:.: ::::.::::::::::::::
NP_005 EKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRD
         350       360       370       380       390       400     

      390       400      
pF1KB9 MLLSGSTFNWPYGSGQ  
       ::::::.::::: : :  
NP_005 MLLSGSSFNWPYMSIQCS
         410       420   

>>NP_066285 (OMIM: 107773,615779) COUP transcription fac  (414 aa)
 initn: 1725 init1: 1111 opt: 1200  Z-score: 1154.6  bits: 222.6 E(85289): 1.4e-57
Smith-Waterman score: 1701; 64.2% identity (81.5% similar) in 400 aa overlap (9-404:31-414)

                                     10        20         30       
pF1KB9                       MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
                                     : : :  .  .  : : : ..  ..:.  :
NP_066 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAG-G
               10        20        30        40        50          

        40         50        60        70        80        90      
pF1KB9 AASDAEPG-DEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNR
        .. . :: :...   ...:::::::::::::: :::::::::::::.:::::::::.::
NP_066 QGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANR
      60        70        80        90       100       110         

        100       110       120       130         140       150    
pF1KB9 DCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLP--GAVAASSGSPPGSALAAV
       .: :::::::::::::::::..::::.:::::::.: . :  :  : ..:.:        
NP_066 NCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDP--------
     120       130       140       150       160       170         

          160       170       180       190       200       210    
pF1KB9 ASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTV
            :   . .:  :. ::::::::..  :::.     . ..::.:.::::::.:::.:
NP_066 -----LNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAV
                  180       190         200       210       220    

          220       230       240       250       260       270    
pF1KB9 EWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAER
       ::::. ::::.: ..::::::::.::::::::::: ..:::.:::::::::::.::.:.:
NP_066 EWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR
          230       240       250       260       270       280    

          280       290       300       310       320       330    
pF1KB9 AVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVA
       .:::::..: :::::.::  :.::::::.:::::.::: ::::::: :::::::::.: :
NP_066 VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCA
          290       300       310       320       330       340    

          340       350       360       370       380       390    
pF1KB9 LTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGS
       : ::::.:::.:: :::.::::::.::.: .:.: ::::.::::::::::::::::::::
NP_066 LEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGS
          350       360       370       380       390       400    

          400    
pF1KB9 TFNWPYGSGQ
       .::::: . :
NP_066 SFNWPYMAIQ
          410    

>>XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP tra  (273 aa)
 initn: 1195 init1: 1089 opt: 1164  Z-score: 1122.6  bits: 216.0 E(85289): 8.7e-56
Smith-Waterman score: 1187; 65.5% identity (83.6% similar) in 281 aa overlap (125-404:5-271)

          100       110       120       130       140       150    
pF1KB9 NRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAV
                                     .:::::.: . :        .:   ::   
XP_016                           MFGYSVQRGRMPPTQP--------NPGQYAL---
                                         10                20      

          160        170       180       190       200       210   
pF1KB9 ASGGDLFPGQ-PVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFST
        ..:: . :.  .:  :. ::::::::..  :.:.     . ..::.:.::::::::::.
XP_016 -TNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAARLLFSA
             30        40        50          60        70        80

           220       230       240       250       260       270   
pF1KB9 VEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAE
       :::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.::.:.
XP_016 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD
               90       100       110       120       130       140

           280       290       300       310       320       330   
pF1KB9 RAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQV
       :.:::::..: :::::.::  :.::::::.:::::.::: ::::::: ::.::::::.: 
XP_016 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC
              150       160       170       180       190       200

           340       350       360       370       380       390   
pF1KB9 ALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSG
       :: ::::.:::.::.:::.::::::.::.: .:.: ::::.:::::::::::::::::::
XP_016 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSG
              210       220       230       240       250       260

           400      
pF1KB9 STFNWPYGSGQ  
       :.::::: : :  
XP_016 SSFNWPYMSIQCS
              270   

>>NP_001138629 (OMIM: 107773,615779) COUP transcription   (261 aa)
 initn: 1111 init1: 1111 opt: 1162  Z-score: 1120.9  bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1162; 67.7% identity (85.8% similar) in 260 aa overlap (145-404:4-261)

          120       130       140       150       160       170    
pF1KB9 KCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLL
                                     . :  .  :...:  :   . .:  :. ::
NP_001                            MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLL
                                          10        20        30   

          180       190       200       210       220       230    
pF1KB9 RAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVAL
       ::::::..  :::.     . ..::.:.::::::.:::.:::::. ::::.: ..:::::
NP_001 RAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVAL
            40          50        60        70        80        90 

          240       250       260       270       280       290    
pF1KB9 LRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGR
       :::.::::::::::: ..:::.:::::::::::.::.:.:.:::::..: :::::.::  
NP_001 LRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKA
             100       110       120       130       140       150 

          300       310       320       330       340       350    
pF1KB9 LQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLL
       :.::::::.:::::.::: ::::::: :::::::::.: :: ::::.:::.:: :::.::
NP_001 LHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL
             160       170       180       190       200       210 

          360       370       380       390       400    
pF1KB9 LRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
       ::::.::.: .:.: ::::.::::::::::::::::::::.::::: . :
NP_001 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
             220       230       240       250       260 

>>NP_001138628 (OMIM: 107773,615779) COUP transcription   (261 aa)
 initn: 1111 init1: 1111 opt: 1162  Z-score: 1120.9  bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1162; 67.7% identity (85.8% similar) in 260 aa overlap (145-404:4-261)

          120       130       140       150       160       170    
pF1KB9 KCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLL
                                     . :  .  :...:  :   . .:  :. ::
NP_001                            MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLL
                                          10        20        30   

          180       190       200       210       220       230    
pF1KB9 RAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVAL
       ::::::..  :::.     . ..::.:.::::::.:::.:::::. ::::.: ..:::::
NP_001 RAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVAL
            40          50        60        70        80        90 

          240       250       260       270       280       290    
pF1KB9 LRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGR
       :::.::::::::::: ..:::.:::::::::::.::.:.:.:::::..: :::::.::  
NP_001 LRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKA
             100       110       120       130       140       150 

          300       310       320       330       340       350    
pF1KB9 LQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLL
       :.::::::.:::::.::: ::::::: :::::::::.: :: ::::.:::.:: :::.::
NP_001 LHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLL
             160       170       180       190       200       210 

          360       370       380       390       400    
pF1KB9 LRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
       ::::.::.: .:.: ::::.::::::::::::::::::::.::::: . :
NP_001 LRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
             220       230       240       250       260 

>>NP_001138627 (OMIM: 107773,615779) COUP transcription   (281 aa)
 initn: 1156 init1: 1111 opt: 1162  Z-score: 1120.5  bits: 215.7 E(85289): 1.1e-55
Smith-Waterman score: 1185; 65.6% identity (82.3% similar) in 282 aa overlap (125-404:15-281)

          100       110       120       130         140       150  
pF1KB9 NRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLP--GAVAASSGSPPGSALA
                                     ::::::.: . :  :  : ..:.:      
NP_001                 MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDP------
                               10        20        30              

            160       170       180       190       200       210  
pF1KB9 AVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFS
              :   . .:  :. ::::::::..  :::.     . ..::.:.::::::.:::
NP_001 -------LNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFS
              40        50        60          70        80         

            220       230       240       250       260       270  
pF1KB9 TVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAA
       .:::::. ::::.: ..::::::::.::::::::::: ..:::.:::::::::::.::.:
NP_001 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSA
      90       100       110       120       130       140         

            280       290       300       310       320       330  
pF1KB9 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ
       .:.:::::..: :::::.::  :.::::::.:::::.::: ::::::: :::::::::.:
NP_001 DRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQ
     150       160       170       180       190       200         

            340       350       360       370       380       390  
pF1KB9 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS
        :: ::::.:::.:: :::.::::::.::.: .:.: ::::.::::::::::::::::::
NP_001 CALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS
     210       220       230       240       250       260         

            400    
pF1KB9 GSTFNWPYGSGQ
       ::.::::: . :
NP_001 GSSFNWPYMAIQ
     270       280 

>>XP_016876575 (OMIM: 602167,608565) PREDICTED: steroid   (508 aa)
 initn: 708 init1: 320 opt: 667  Z-score: 643.6  bits: 128.3 E(85289): 4.1e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:42-429)

                                          10        20             
pF1KB9                           MAMVTGGWG-GPGGDTNGVDKA--------GGYP
                                     .::.: . :  .::.:.         :: :
XP_016 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
              20        30        40        50        60        70 

           30        40        50          60        70        80  
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
        : . .: ::  :   :.    :   .   .  :.:::: .:: :::: .::.::.::::
XP_016 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
              80          90       100       110       120         

             90       100       110       120       130        140 
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
       .:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:.  :.  .        
XP_016 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
     130       140       150       160       170       180         

             150       160       170       180       190       200 
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
       .: : :  .:     .      .:...... :: :::    :  .   :   : . .. .
XP_016 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
     190       200            210       220         230       240  

             210       220       230       240       250       260 
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
       .:.:: : :   . ::.: : :  : ..::..::. .: :...:. .  .::      :.
XP_016 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
            250       260       270       280       290         300

             270       280       290       300       310       320 
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
        :  .       : .....  ::. . : .  .:.:.. :.  :::.:: . :.  . : 
XP_016 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
         :..::.  . :: .:  .:   .: : :.::: :: :: . :. ..... ..: ::.:
XP_016 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
              370       380       390       400       410       420

             390       400                                         
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ                                     
       .. :. .::                                                   
XP_016 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
              430       440       450       460       470       480

>>NP_004443 (OMIM: 602167,608565) steroid hormone recept  (508 aa)
 initn: 708 init1: 320 opt: 667  Z-score: 643.6  bits: 128.3 E(85289): 4.1e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:42-429)

                                          10        20             
pF1KB9                           MAMVTGGWG-GPGGDTNGVDKA--------GGYP
                                     .::.: . :  .::.:.         :: :
NP_004 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
              20        30        40        50        60        70 

           30        40        50          60        70        80  
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
        : . .: ::  :   :.    :   .   .  :.:::: .:: :::: .::.::.::::
NP_004 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
              80          90       100       110       120         

             90       100       110       120       130        140 
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
       .:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:.  :.  .        
NP_004 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
     130       140       150       160       170       180         

             150       160       170       180       190       200 
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
       .: : :  .:     .      .:...... :: :::    :  .   :   : . .. .
NP_004 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
     190       200            210       220         230       240  

             210       220       230       240       250       260 
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
       .:.:: : :   . ::.: : :  : ..::..::. .: :...:. .  .::      :.
NP_004 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
            250       260       270       280       290         300

             270       280       290       300       310       320 
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
        :  .       : .....  ::. . : .  .:.:.. :.  :::.:: . :.  . : 
NP_004 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
         :..::.  . :: .:  .:   .: : :.::: :: :: . :. ..... ..: ::.:
NP_004 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
              370       380       390       400       410       420

             390       400                                         
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ                                     
       .. :. .::                                                   
NP_004 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
              430       440       450       460       470       480

>>XP_011534856 (OMIM: 602167,608565) PREDICTED: steroid   (529 aa)
 initn: 708 init1: 320 opt: 667  Z-score: 643.4  bits: 128.3 E(85289): 4.3e-29
Smith-Waterman score: 680; 32.6% identity (59.6% similar) in 399 aa overlap (5-390:63-450)

                                          10        20             
pF1KB9                           MAMVTGGWG-GPGGDTNGVDKA--------GGYP
                                     .::.: . :  .::.:.         :: :
XP_011 CGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTP
             40        50        60        70        80        90  

           30        40        50          60        70        80  
pF1KB9 -RAAEDDSASPPGAASDAEPGDEERPGL--QVDCVVCGDKSSGKHYGVFTCEGCKSFFKR
        : . .: ::  :   :.    :   .   .  :.:::: .:: :::: .::.::.::::
XP_011 CRKSYEDCAS--GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKR
            100         110       120       130       140       150

             90       100       110       120       130        140 
pF1KB9 SIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG-AVAA
       .:. :. :.: .. .:.: ...:..:: ::. ::..::: ::.:.  :.  .        
XP_011 TIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRL
              160       170       180       190       200       210

             150       160       170       180       190       200 
pF1KB9 SSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDN
       .: : :  .:     .      .:...... :: :::    :  .   :   : . .. .
XP_011 DSESSPYLSLQISPPAK-----KPLTKIVSYLLVAEPDKLYA--MPPPGMPEGDIKALTT
              220            230       240         250       260   

             210       220       230       240       250       260 
pF1KB9 VCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLA
       .:.:: : :   . ::.: : :  : ..::..::. .: :...:. .  .::      :.
XP_011 LCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK--LV
           270       280       290       300       310         320 

             270       280       290       300       310       320 
pF1KB9 AAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDP
        :  .       : .....  ::. . : .  .:.:.. :.  :::.:: . :.  . : 
XP_011 YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
             330       340       350       360       370       380 

             330       340       350       360       370       380 
pF1KB9 AHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTP
         :..::.  . :: .:  .:   .: : :.::: :: :: . :. ..... ..: ::.:
XP_011 EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
             390       400       410       420       430       440 

             390       400                                         
pF1KB9 IETLIRDMLLSGSTFNWPYGSGQ                                     
       .. :. .::                                                   
XP_011 MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
             450       460       470       480       490       500 




404 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 18:31:32 2016 done: Fri Nov  4 18:31:34 2016
 Total Scan time: 10.140 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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