Result of FASTA (omim) for pF1KB9580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9580, 181 aa
  1>>>pF1KB9580 181 - 181 aa - 181 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0613+/-0.000304; mu= 10.3648+/- 0.019
 mean_var=93.5608+/-18.968, 0's: 0 Z-trim(119.7): 62  B-trim: 393 in 2/55
 Lambda= 0.132595
 statistics sampled from 33978 (34045) to 33978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.399), width:  16
 Scan time:  5.360

The best scores are:                                      opt bits E(85289)
NP_065697 (OMIM: 609154) achaete-scute homolog 3 [ ( 181) 1247 247.7 7.7e-66
NP_982260 (OMIM: 609155) achaete-scute homolog 4 [ ( 173)  308 68.1 8.7e-12
NP_004307 (OMIM: 100790,209880) achaete-scute homo ( 236)  222 51.7   1e-06
NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193)  213 49.9 2.8e-06
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328)  178 43.4 0.00045
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172)  161 39.9  0.0025
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172)  161 39.9  0.0025
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206)  161 40.0  0.0029
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280)  161 40.1  0.0037
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217)  159 39.6   0.004
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302)  161 40.1   0.004
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199)  158 39.4  0.0042
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331)  161 40.1  0.0043
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331)  161 40.1  0.0043
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331)  161 40.1  0.0043
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331)  161 40.1  0.0043
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331)  161 40.1  0.0043
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  161 40.1  0.0043
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108)  154 38.5  0.0044
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351)  161 40.1  0.0045
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160)  156 39.0  0.0046
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160)  156 39.0  0.0046
NP_001004311 (OMIM: 608697,612310) factor in the g ( 219)  153 38.5  0.0089
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202)  152 38.3  0.0095
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202)  152 38.3  0.0095


>>NP_065697 (OMIM: 609154) achaete-scute homolog 3 [Homo  (181 aa)
 initn: 1247 init1: 1247 opt: 1247  Z-score: 1303.1  bits: 247.7 E(85289): 7.7e-66
Smith-Waterman score: 1247; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)

               10        20        30        40        50        60
pF1KB9 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 DSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
              130       140       150       160       170       180

        
pF1KB9 V
       :
NP_065 V
        

>>NP_982260 (OMIM: 609155) achaete-scute homolog 4 [Homo  (173 aa)
 initn: 320 init1: 300 opt: 308  Z-score: 332.6  bits: 68.1 E(85289): 8.7e-12
Smith-Waterman score: 308; 47.3% identity (61.2% similar) in 129 aa overlap (22-149:10-129)

               10        20        30        40        50        60
pF1KB9 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
                            :: :  :.   :. .  . :  :  .:    : ::    
NP_982             MMETRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVAL-RL----
                           10        20        30        40        

               70         80        90       100       110         
pF1KB9 DSLILGNYSEPCPFSFP-MPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHH
       :.         :  ..  .: :     . .. ::: :::::::::::.:::::::.:: :
NP_982 DAACWEWARSGCARGWQYLPVP----LDSAFEPAFLRKRNERERQRVRCVNEGYARLRDH
            50        60            70        80        90         

     120       130       140       150       160       170         
pF1KB9 LPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFR
       ::.:  .::::::::::::: ::..:: ::                              
NP_982 LPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKAS
     100       110       120       130       140       150         

>>NP_004307 (OMIM: 100790,209880) achaete-scute homolog   (236 aa)
 initn: 214 init1: 214 opt: 222  Z-score: 241.7  bits: 51.7 E(85289): 1e-06
Smith-Waterman score: 222; 43.3% identity (63.9% similar) in 97 aa overlap (82-175:104-200)

              60        70        80        90          100        
pF1KB9 ELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYG---PAFTRKRNERERQRVKC
                                     :. :  ::     :: . .::::::.::: 
NP_004 PSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKL
            80        90       100       110       120       130   

      110       120       130       140       150       160        
pF1KB9 VNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIA
       :: :.: ::.:.:.   .:..:::::::.:..::  ::.::    : .    . : :   
NP_004 VNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTI
           140       150       160       170       180       190   

      170       180                               
pF1KB9 TTSHHADPMFRIV                              
       . ..  :                                    
NP_004 SPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
           200       210       220       230      

>>NP_005161 (OMIM: 601886) achaete-scute homolog 2 [Homo  (193 aa)
 initn: 212 init1: 198 opt: 213  Z-score: 233.7  bits: 49.9 E(85289): 2.8e-06
Smith-Waterman score: 213; 42.6% identity (61.4% similar) in 101 aa overlap (53-149:6-106)

             30        40        50        60        70        80  
pF1KB9 LPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPN
                                     :::   :.  . .:  ..  : :  .   .
NP_005                          MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCS
                                        10        20        30     

                 90       100       110       120       130        
pF1KB9 YR----GCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAA
        :      : . : : . .::::::.::: :: :.  ::.:.:.    :.::::::::.:
NP_005 RRRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSA
          40        50        60        70        80        90     

      140       150       160       170       180                  
pF1KB9 IKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV                 
       ..::  :: ::                                                 
NP_005 VEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGS
         100       110       120       130       140       150     

>>NP_835455 (OMIM: 607194,609069,615935) pancreas transc  (328 aa)
 initn: 195 init1: 174 opt: 178  Z-score: 194.2  bits: 43.4 E(85289): 0.00045
Smith-Waterman score: 178; 51.9% identity (74.1% similar) in 54 aa overlap (99-152:169-222)

       70        80        90       100       110       120        
pF1KB9 SEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKR
                                     : :::.:.. .:...  :: :.:    :::
NP_835 RGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKR
      140       150       160       170       180       190        

      130       140       150       160       170       180        
pF1KB9 LSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV       
       ::::.::: :: :::.:. :.  :                                    
NP_835 LSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICH
      200       210       220       230       240       250        

>>NP_001277335 (OMIM: 187040,613065) T-cell acute lympho  (172 aa)
 initn: 169 init1: 155 opt: 161  Z-score: 180.6  bits: 39.9 E(85289): 0.0025
Smith-Waterman score: 161; 41.0% identity (61.4% similar) in 83 aa overlap (77-155:12-90)

         50        60        70        80        90           100  
pF1KB9 SPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGP--AFTRK--RNERE
                                     : ::      : . ::    .:.   : ::
NP_001                    MFTTNNRVKRRPSPYE----MEITDGPHTKVVRRIFTNSRE
                                  10            20        30       

            110       120       130       140       150       160  
pF1KB9 RQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGK
       : : . :: ..:.::. .: .  .:.::: : :: :.::::.: .::  .. :       
NP_001 RWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKT
        40        50        60        70        80        90       

            170       180                                          
pF1KB9 VSSMIATTSHHADPMFRIV                                         
                                                                   
NP_001 GKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARS
       100       110       120       130       140       150       

>>XP_016857682 (OMIM: 187040,613065) PREDICTED: T-cell a  (172 aa)
 initn: 169 init1: 155 opt: 161  Z-score: 180.6  bits: 39.9 E(85289): 0.0025
Smith-Waterman score: 161; 41.0% identity (61.4% similar) in 83 aa overlap (77-155:12-90)

         50        60        70        80        90           100  
pF1KB9 SPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGP--AFTRK--RNERE
                                     : ::      : . ::    .:.   : ::
XP_016                    MFTTNNRVKRRPSPYE----MEITDGPHTKVVRRIFTNSRE
                                  10            20        30       

            110       120       130       140       150       160  
pF1KB9 RQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGK
       : : . :: ..:.::. .: .  .:.::: : :: :.::::.: .::  .. :       
XP_016 RWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKT
        40        50        60        70        80        90       

            170       180                                          
pF1KB9 VSSMIATTSHHADPMFRIV                                         
                                                                   
XP_016 GKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARS
       100       110       120       130       140       150       

>>XP_005259969 (OMIM: 151440) PREDICTED: protein lyl-1 i  (206 aa)
 initn: 177 init1: 145 opt: 161  Z-score: 179.5  bits: 40.0 E(85289): 0.0029
Smith-Waterman score: 169; 31.8% identity (55.0% similar) in 129 aa overlap (33-160:24-143)

             10        20        30        40         50        60 
pF1KB9 DNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPY-SEELPRLPFPSD
                                     : ...: ::.  ..: : .   :   :::.
XP_005        MPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSS
                      10        20        30        40        50   

              70        80        90       100       110       120 
pF1KB9 SLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLP
        :        : ...   .   .  .     .::   : ::: : . :: ..:.::. ::
XP_005 RL--KRRPSHCELDLAEGHQPQKVARR----VFT---NSRERWRQQNVNGAFAELRKLLP
              60        70            80           90       100    

             130       140       150       160       170       180 
pF1KB9 EEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV
        .  ...::: :.:: :.:::..:  ::  . :    .:                     
XP_005 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRG
          110       120       130       140       150       160    

XP_005 SGRRAEAAARSQPAPPADPDGSPGGAARPIKMEQTALSPEVR
          170       180       190       200      

>>NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapiens]   (280 aa)
 initn: 206 init1: 145 opt: 161  Z-score: 177.6  bits: 40.1 E(85289): 0.0037
Smith-Waterman score: 184; 32.0% identity (53.9% similar) in 178 aa overlap (4-160:47-217)

                                             10              20    
pF1KB9                            MMDNRGNSS---LPDKLPIF------PDSARLP
                                     .::.::   ::  .:..      : .. .:
NP_005 KAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMP
         20        30        40        50        60        70      

           30         40        50        60         70         80 
pF1KB9 LTRSFYLEP-MVTFHVHPEAPVSSPYSEELPRLPFPS-DSLILGNYSEPCPFS-FPMPYP
        :.   :.: .. . .   ::   : .  :   : :  .:. .:  .   ::: ::    
NP_005 TTELGTLRPPLLQLSTLGTAP---P-TLALHYHPHPFLNSVYIGPAG---PFSIFPSSRL
         80        90           100       110          120         

                    90          100       110       120       130  
pF1KB9 NYRG--CEYS----YGPAFTRKR---NERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKV
       . :   :: .    . :  . .:   : ::: : . :: ..:.::. :: .  ...::: 
NP_005 KRRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKN
     130       140       150       160       170       180         

            140       150       160       170       180            
pF1KB9 ETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV           
       :.:: :.:::..:  ::  . :    .:                                
NP_005 EVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARS
     190       200       210       220       230       240         

>>NP_068808 (OMIM: 602407) heart- and neural crest deriv  (217 aa)
 initn: 140 init1: 140 opt: 159  Z-score: 177.1  bits: 39.6 E(85289): 0.004
Smith-Waterman score: 169; 29.5% identity (56.6% similar) in 122 aa overlap (40-152:37-158)

      10        20        30        40        50        60         
pF1KB9 LPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYS
                                     : : :    .    :..  :. :. :.   
NP_068 FPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSP
         10        20        30        40        50        60      

      70        80        90                100       110       120
pF1KB9 EPCPFSFPMPYPNYRGCEYSYGPAF------TRKR---NERERQRVKCVNEGYAQLRHHL
       :    .  . . .: :   . ::        ...:   :..::.:.. .: ..:.::. .
NP_068 EYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECI
         70        80        90       100       110       120      

              130       140       150       160       170       180
pF1KB9 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
       :.   . .:::..::: : .:: ::..::  :                            
NP_068 PNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELN
        130       140       150       160       170       180      

                                      
pF1KB9 V                              
                                      
NP_068 EILKSTVSSNDKKTKGRTGWPQHVWALELKQ
        190       200       210       




181 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:28:38 2016 done: Fri Nov  4 17:28:38 2016
 Total Scan time:  5.360 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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