Result of FASTA (ccds) for
pF1KB8962
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8962, 342 aa
1>>>pF1KB8962 342 - 342 aa - 342 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4652+/-0.000887; mu= 3.1077+/- 0.053
mean_var=196.0181+/-40.249, 0's: 0 Z-trim(112.8): 140 B-trim: 8 in 1/51
Lambda= 0.091606
statistics sampled from 13328 (13475) to 13328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.414), width: 16
Scan time: 2.550
The best scores are: opt bits E(32554)
CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 ( 342) 2323 319.0 3.5e-87
CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 ( 340) 958 138.6 7.1e-33
CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 ( 410) 605 92.0 9.1e-19
CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 ( 260) 449 71.3 1e-12
CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 ( 272) 438 69.8 2.9e-12
CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 ( 250) 427 68.3 7.5e-12
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 404 65.4 8e-11
>>CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 (342 aa)
initn: 2323 init1: 2323 opt: 2323 Z-score: 1678.6 bits: 319.0 E(32554): 3.5e-87
Smith-Waterman score: 2323; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342)
10 20 30 40 50 60
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 SPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 KSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 SPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE
250 260 270 280 290 300
310 320 330 340
pF1KB8 ISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
::::::::::::::::::::::::::::::::::::::::::
CCDS88 ISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
310 320 330 340
>>CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 (340 aa)
initn: 947 init1: 589 opt: 958 Z-score: 703.7 bits: 138.6 E(32554): 7.1e-33
Smith-Waterman score: 958; 50.5% identity (75.1% similar) in 321 aa overlap (25-342:28-340)
10 20 30 40 50
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGS-DFNCGVMRGCGLAPSLSKR
:: ::.::: : :.. :. ::: :::.::
CCDS22 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 DEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSA
: . ....:..: :. :.::: ::. . :.:::: . . .::. ..:::. :::::
CCDS22 -EVNHQNMGMNVHP-YIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSD
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 EKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSALDKTPHCSGANDFEAPFE
.. . :. :.. .:::: :. :::::.:.: : .: : :: . . :. :.
CCDS22 KRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTY-ATGKTQEYN--NSPEGSST
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 QRASLNPRAEHLESPQLGG-KVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKER
.::::. .:::.. .... . . . :.... .: . : : : ..
CCDS22 VMLQLNPRGA--AKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEE-RSCL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 AKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
:... :::.....:.:::::... :.::::::::::::::::::::::::::::::::::
CCDS22 AEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
240 250 260 270 280 290
300 310 320 330 340
pF1KB8 RERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
:::::::::..:::::::::::::::::::::.:::::::::.:..:.
CCDS22 RERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
300 310 320 330 340
>>CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 (410 aa)
initn: 673 init1: 522 opt: 605 Z-score: 450.4 bits: 92.0 E(32554): 9.1e-19
Smith-Waterman score: 752; 42.1% identity (62.8% similar) in 368 aa overlap (17-342:49-410)
10 20 30 40
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRG
:. ::: : .:.:. ..:. : ...
CCDS54 SCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYG-LQS
20 30 40 50 60 70
50 60 70 80 90
pF1KB8 CGLAPSLS-KRDEGSSPS-------LALNTYPSYLSQLDSWGDPKAAYRLEQPVGRP---
::: :.:. ::.:..::. :. ... : .: : : . :.: : : :
CCDS54 CGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPP
80 90 100 110 120 130
100 110 120 130
pF1KB8 ----------------LSSCSYPPSVKEENVCCMY-SAEKRAKSGPEAALYSH----PLP
.:::. ..:::. :.: ::.: : . :: . : :
CCDS54 QQQPPPPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPP
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB8 ESC-LGEHE-VPVPSYYRASPSY-SALDKTPHCSGANDFEA-PFEQRASLNPRAEHLESP
..: :: ::::.:.: : .: .: .::... : :: :. :. :
CCDS54 DGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFP--AQPPGRGFDLPPA
200 210 220 230 240 250
200 210 220 230 240
pF1KB8 QLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKG------SPSESEKERAKAADSSPDT
.:... . .. .. : :. . : .: .: : : .:. ..:: .
CCDS54 LASGSADAARKERALDSPPPPT--LACGSGGGSQGDEEAHASSSAAEELSPAPSESSKAS
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB8 SDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKT
.... . :.::.. ::::::::::::::::::::::::::::::::::::::::::..
CCDS54 PEKDSLGNSKGENAA-NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRS
320 330 340 350 360 370
310 320 330 340
pF1KB8 INLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
..::::::::::::::::::::::::::::::.::::.
CCDS54 VHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
380 390 400 410
>>CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 (260 aa)
initn: 439 init1: 418 opt: 449 Z-score: 341.7 bits: 71.3 E(32554): 1e-12
Smith-Waterman score: 470; 35.9% identity (60.2% similar) in 259 aa overlap (95-334:6-258)
70 80 90 100 110 120
pF1KB8 ALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGP
:.:. ....: . : . . :
CCDS88 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHP
10 20 30
130 140 150 160 170 180
pF1KB8 EAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRA
:: : .:. : . : :. .:. . . .: : .. :. . :. .
CCDS88 AAARPSGLVPD-C---SDFPSCSFA-PKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADT
40 50 60 70 80 90
190 200 210 220 230
pF1KB8 EHLES--PQLGGKVSFPETPKSDSQTP-SPNEIKTEQSLAGPK----------GSPSESE
..... :.: :::: : . . .:. ... :: :::.:
CCDS88 RYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGEL-
100 110 120 130 140
240 250 260 270 280
pF1KB8 KERAKAADSSPD------TSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEK
..:: . ::. .. .: : .. : ..::. :.: :::::::::.:::::::
CCDS88 RDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEK
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB8 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
::::::::::.:: :.....:::.:::::::::::::.::::.:. .:
CCDS88 EFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
210 220 230 240 250 260
>>CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 (272 aa)
initn: 446 init1: 392 opt: 438 Z-score: 333.6 bits: 69.8 E(32554): 2.9e-12
Smith-Waterman score: 438; 40.9% identity (63.1% similar) in 203 aa overlap (134-329:69-267)
110 120 130 140 150 160
pF1KB8 SVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPH
: : . ::. :.. . ..:
CCDS54 PRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 CSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSF---PETPKSDSQTPSPNEIKTEQSL
..: : . .:. :.: : : .. . :: : : . :. ::
CCDS54 AAAAPDGRY---MRSWLEPTPGALSFAGLPSSRPYGIKPE-PLSARRGDCPTLDTHTLSL
100 110 120 130 140 150
230 240 250 260 270
pF1KB8 AGPK-GSPSESEKERAKAADSSPDTSDNEA---KEEIKAENTTGNWLTAKSGRKKRCPYT
. ::: ..... . . : ....::. : : .: ..::: :.: ::::::::
CCDS54 TDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYT
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 KHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELT
:::::::::::::::::::.:: :... .:::.:::::::::::::.::.:..
CCDS54 KHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
220 230 240 250 260 270
340
pF1KB8 SNFNFT
>>CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 (250 aa)
initn: 429 init1: 404 opt: 427 Z-score: 326.3 bits: 68.3 E(32554): 7.5e-12
Smith-Waterman score: 451; 42.2% identity (64.9% similar) in 211 aa overlap (140-329:43-246)
110 120 130 140 150 160
pF1KB8 VCCMYSAEKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSA--LDKTPHCSG
:: : : :. .: ..: .:: ::
CCDS11 DSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASG
20 30 40 50 60 70
170 180 190 200 210 220
pF1KB8 A-NDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNE--IKTEQSLAGP
. . :. : .. : :: : .. . .:.... .:. .. .:.: :..:
CCDS11 SLPSVYHPYIQPQGVPP----AESRYL--RTWLEPAPRGEA-APGQGQAAVKAEPLLGAP
80 90 100 110 120
230 240 250 260
pF1KB8 -----KGSPSES-EKERAKAA---DSSPDTSDN------EAKEEIKAENTTGNWLTAKSG
.:.: : : .. : .. : .:: : ::. : ..::: :.:.
CCDS11 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB8 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR
:::::::::.:::::::::::::::::.:: :... .::..:::::::::::::.::::.
CCDS11 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK
190 200 210 220 230 240
330 340
pF1KB8 ENRIRELTSNFNFT
:
CCDS11 EQGKE
250
>>CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 (352 aa)
initn: 437 init1: 384 opt: 404 Z-score: 307.8 bits: 65.4 E(32554): 8e-11
Smith-Waterman score: 422; 38.5% identity (61.5% similar) in 213 aa overlap (122-329:150-346)
100 110 120 130 140
pF1KB8 VGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVP-----
::: . . ::. . .:.:
CCDS22 MEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPET----RAAPAPATAAS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 SYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDS
. .: : :. .: .:: : . .. . : : .. . :: : .
CCDS22 TTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGG-----TGPGAGI
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QTPSPNEIKTEQSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAK
. . . ..: : . . :. : ::. : :.:. .... .: ..::. :.
CCDS22 GAATGTGGSSEPSACSDHPIPGCSLKEEEKQ-HSQPQ------QQQLDPNNPAANWIHAR
240 250 260 270 280
270 280 290 300 310 320
pF1KB8 SGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKM
: :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::
CCDS22 STRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKM
290 300 310 320 330 340
330 340
pF1KB8 NRENRIRELTSNFNFT
..:
CCDS22 SKEKCPKGD
350
342 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:42:37 2016 done: Fri Nov 4 16:42:38 2016
Total Scan time: 2.550 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]