Result of FASTA (omim) for pF1KB8917
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8917, 260 aa
  1>>>pF1KB8917 260 - 260 aa - 260 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2148+/-0.000347; mu= 8.0237+/- 0.022
 mean_var=186.1210+/-38.059, 0's: 0 Z-trim(120.8): 201  B-trim: 362 in 2/54
 Lambda= 0.094011
 statistics sampled from 36246 (36527) to 36246 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.428), width:  16
 Scan time:  5.820

The best scores are:                                      opt bits E(85289)
NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 1815 257.7 1.5e-68
NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250)  714 108.4 1.3e-23
NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272)  693 105.6 9.9e-23
NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352)  531 83.7 4.9e-16
NP_061824 (OMIM: 142957) homeobox protein Hox-A10  ( 410)  464 74.7 2.9e-13
NP_059105 (OMIM: 605560) homeobox protein Hox-C10  ( 342)  449 72.6 1.1e-12
NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340)  431 70.2 5.7e-12
NP_067015 (OMIM: 142986) homeobox protein Hox-D11  ( 338)  339 57.7 3.3e-08
NP_055027 (OMIM: 605559) homeobox protein Hox-C11  ( 304)  335 57.1 4.4e-08
NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313)  324 55.6 1.3e-07
NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242)  322 55.2 1.3e-07
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289)  313 54.1 3.4e-07
NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233)  309 53.4 4.3e-07
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290)  310 53.7 4.5e-07
NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217)  307 53.1 4.9e-07
NP_005915 (OMIM: 600535) homeobox protein MOX-2 [H ( 304)  306 53.1 6.8e-07
XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242)  304 52.8   7e-07
NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222)  302 52.5   8e-07
XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243)  301 52.4 9.3e-07
NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243)  301 52.4 9.3e-07
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270)  301 52.4   1e-06
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320)  299 52.2 1.4e-06
NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230)  294 51.4 1.7e-06
NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313)  290 51.0 3.1e-06
NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106)  282 49.4 3.2e-06
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255)  288 50.6 3.3e-06
NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376)  286 50.5 5.1e-06
NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269)  283 50.0 5.4e-06
NP_776272 (OMIM: 142975) homeobox protein Hox-C12  ( 282)  282 49.9 6.1e-06
NP_000513 (OMIM: 140000,142959,176305) homeobox pr ( 388)  283 50.1 6.9e-06
NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224)  277 49.1 8.4e-06
XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224)  277 49.1 8.4e-06
XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224)  277 49.1 8.4e-06
XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288)  277 49.2   1e-05
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  278 49.5 1.2e-05
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  278 49.5 1.2e-05
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443)  278 49.5 1.2e-05
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  278 49.5 1.2e-05
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  278 49.5 1.2e-05
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443)  278 49.5 1.2e-05
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443)  278 49.5 1.2e-05
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356)  274 48.9 1.5e-05
XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321)  273 48.7 1.6e-05
NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153)  267 47.5 1.7e-05
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264)  270 48.2 1.8e-05
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264)  270 48.2 1.8e-05
NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328)  271 48.4 1.9e-05
XP_011533180 (OMIM: 600297) PREDICTED: homeobox pr ( 204)  266 47.5 2.2e-05
NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235)  267 47.7 2.2e-05
NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251)  266 47.6 2.6e-05


>>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo  (260 aa)
 initn: 1815 init1: 1815 opt: 1815  Z-score: 1351.7  bits: 257.7 E(85289): 1.5e-68
Smith-Waterman score: 1815; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260)

               10        20        30        40        50        60
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWF
              190       200       210       220       230       240

              250       260
pF1KB8 QNRRMKMKKMNKEKTDKEQS
       ::::::::::::::::::::
NP_008 QNRRMKMKKMNKEKTDKEQS
              250       260

>>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo  (250 aa)
 initn: 769 init1: 485 opt: 714  Z-score: 544.9  bits: 108.4 E(85289): 1.3e-23
Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-254:1-247)

               10        20        30        40        50        60
pF1KB8 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
       :: .: .:.:::::.:::..::   ..:: .: . :..:  : .    .:::::: ::  
NP_076 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP
               10        20         30         40         50       

               70            80         90       100       110     
pF1KB8 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH
       ::..::::.  ..:     :::::  ::    :..::.::::::   . . :    :  .
NP_076 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ
        60        70        80        90       100           110   

         120       130         140        150       160       170  
pF1KB8 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE
        :.: .   :     .:::   .. :.: .  : :.    . :     .     ::. ::
NP_076 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE
           120            130       140       150       160        

            180       190       200       210       220       230  
pF1KB8 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT
       .    : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::.
NP_076 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS
      170          180       190       200       210       220     

            240       250       260
pF1KB8 ERQVKIWFQNRRMKMKKMNKEKTDKEQS
       :::::::::::::::::::::.      
NP_076 ERQVKIWFQNRRMKMKKMNKEQGKE   
         230       240       250   

>>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo  (272 aa)
 initn: 800 init1: 537 opt: 693  Z-score: 529.1  bits: 105.6 E(85289): 9.9e-23
Smith-Waterman score: 824; 51.3% identity (70.4% similar) in 277 aa overlap (1-258:1-272)

               10         20          30        40        50       
pF1KB8 MSATGPISNYYVDS-LISHDNEDLLA-SRF-PATGAHPAAARPSGLVPDCSDFPSCSFAP
       :..:: ..:::::: :.. :  : :. .:. :.: ..:   : .. . .  ::  :::  
NP_689 MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPP--RQAATLAEHPDFSPCSFQS
               10        20        30          40        50        

        60        70                  80            90       100   
pF1KB8 KPAVFSTSWAPVPSQSS-----VVYH-----PY-GPQPHLGA---DTRYMRTWLEPLSGA
       : .::..:: :: . ..     .:::     ::  ::  ..:   : ::::.::::  ::
NP_689 KATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGA
       60        70        80        90       100       110        

           110       120       130         140       150       160 
pF1KB8 VSFPSFPAGGRHYALKPDAYPGRRADCGPGEGR--SYPDYMYGSPGELRDRAPQTLPSPE
       .:: ..:.. : :..::.   .::.::   . .  :  ::  :::   :.. :.     :
NP_689 LSFAGLPSS-RPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSE
      120        130       140       150       160       170       

             170       180       190       200       210       220 
pF1KB8 ADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDR
        .:   :    .:  .::.::.:::.::::::::::::::.:::::::::::::::::::
NP_689 NNAENESGG--DKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDR
       180         190       200       210       220       230     

             230       240       250       260
pF1KB8 RYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
       ::::::.:::::::::::::::::::::.::...  :  
NP_689 RYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE  
         240       250       260       270    

>>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo  (352 aa)
 initn: 827 init1: 515 opt: 531  Z-score: 408.9  bits: 83.7 E(85289): 4.9e-16
Smith-Waterman score: 703; 47.8% identity (59.5% similar) in 289 aa overlap (49-257:62-350)

       20        30        40        50        60        70        
pF1KB8 DNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQS-----
                                     .: ::::::. ::::.::. ::::      
NP_055 EVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAA
              40        50        60        70        80        90 

             80        90           100                            
pF1KB8 -SVVYHPYGPQPHLGADT----RYMRTWLEPLSG-------------------AVSFPSF
        : .:::: : : :.:..    ::.:.:.::: :                       :: 
NP_055 MSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSG
             100       110       120       130       140       150 

     110       120                            130          140     
pF1KB8 PAGGRHYALKPD--AYPG-------------------RRADCG---PGEGRSYPDYMYGS
       ::.::::..::.  : :.                   .:..:.    ..: : :..  .:
NP_055 PANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNS
             160       170       180       190       200       210 

                       150       160            170                
pF1KB8 --------------PGELRDRAPQTLPSPEADA-----LAGSKHKEE--------KADLD
                     ::     :  :  : : .:     . : . :::        . .::
NP_055 FLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLD
             220       230       240       250       260       270 

      180       190       200       210       220       230        
pF1KB8 PSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKI
       :.::.::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_055 PNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKI
             280       290       300       310       320       330 

      240       250       260
pF1KB8 WFQNRRMKMKKMNKEKTDKEQS
       ::::::::::::.:::  :   
NP_055 WFQNRRMKMKKMSKEKCPKGD 
             340       350   

>>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom  (410 aa)
 initn: 470 init1: 392 opt: 464  Z-score: 359.0  bits: 74.7 E(85289): 2.9e-13
Smith-Waterman score: 472; 40.3% identity (58.8% similar) in 243 aa overlap (25-258:175-402)

                     10        20        30          40        50  
pF1KB8       MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPA--AARPSGLVPDCSDFPS
                                     :.. : ..:  :  :  : :  ::   . .
NP_061 PQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGT
          150       160       170       180       190       200    

             60        70        80        90       100       110  
pF1KB8 CSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAG
        : .: :. :  : :   ...       :   .:::     .    :  :    :.. .:
NP_061 SSGVPVPGYFRLSQAYGTAKG--YGSGGGGAQQLGAGPFPAQP---PGRGFDLPPALASG
          210       220         230       240          250         

            120          130       140       150           160     
pF1KB8 GRHYALKP---DAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAP----QTLPSPEADAL
       .   : :    :. :     :: : : .  .  ..: .  .. .:    ..  ::: :.:
NP_061 SADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSL
     260       270       280       290       300       310         

         170       180       190       200       210       220     
pF1KB8 AGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEV
       ..::   :.:        :::. :.: :::::::::.:::::::::::::::::.:: :.
NP_061 GNSKG--ENA--------ANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEI
     320                 330       340       350       360         

         230       240       250       260      
pF1KB8 ARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS      
       .: ..::.:::::::::::::.::::.:.  .:        
NP_061 SRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
     370       380       390       400       410

>>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom  (342 aa)
 initn: 439 init1: 418 opt: 449  Z-score: 349.0  bits: 72.6 E(85289): 1.1e-12
Smith-Waterman score: 470; 35.9% identity (60.2% similar) in 259 aa overlap (6-258:95-334)

                                        10        20        30     
pF1KB8                          MSATGPISNYYVDSLISHDNEDLLASRFPATGAHP
                                     :.:.      ....:   . :    . . :
NP_059 ALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGP
           70        80        90       100       110       120    

          40            50         60        70        80        90
pF1KB8 AAARPSGLVPD-C---SDFPSCSFA-PKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADT
        ::  :  .:. :    . :  :.   .:.  . . .:  : ..    :.  .  :.  .
NP_059 EAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRA
          130       140       150       160       170       180    

              100       110       120       130       140          
pF1KB8 RYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGEL-
       .....    :.: ::::  : .  .   .:.    ...  ::           :::.:  
NP_059 EHLES--PQLGGKVSFPETPKSDSQTP-SPNEIKTEQSLAGPK----------GSPSESE
            190       200        210       220                 230 

     150       160       170       180       190       200         
pF1KB8 RDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEK
       ..::  .  ::.      .. .: : ..   : ..::. :.: :::::::::.:::::::
NP_059 KERAKAADSSPD------TSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEK
             240             250       260       270       280     

     210       220       230       240       250       260      
pF1KB8 EFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS      
       ::::::::::.:: :.....:::.:::::::::::::.::::.:.  .:        
NP_059 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
         290       300       310       320       330       340  

>>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D  (340 aa)
 initn: 485 init1: 411 opt: 431  Z-score: 335.8  bits: 70.2 E(85289): 5.7e-12
Smith-Waterman score: 435; 39.4% identity (66.2% similar) in 216 aa overlap (43-258:134-332)

             20        30        40        50        60        70  
pF1KB8 DSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQ
                                     :::.     .   .: :. :  : . . ..
NP_002 TTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVEN-PEVPVPGYFRLSQTYATGK
           110       120       130       140        150       160  

             80        90       100       110       120       130  
pF1KB8 SSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGP
       .    . :. .:. :..: ...  :.:  ::.. :.. :.  ..  : .   . .     
NP_002 T----QEYNNSPE-GSSTVMLQ--LNP-RGAAK-PQLSAAQLQMEKKMNEPVSGQEPTKV
                170          180         190       200       210   

            140       150       160       170       180       190  
pF1KB8 GEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARST
       .. .: :.   : : :    :  .. :::.      ..:: : ..  ..:..::. :.: 
NP_002 SQVES-PEAKGGLPEERSCLAEVSVSSPEV------QEKESKEEIKSDTPTSNWLTAKSG
            220       230       240             250       260      

            200       210       220       230       240       250  
pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNK
       :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::..
NP_002 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR
        270       280       290       300       310       320      

            260      
pF1KB8 EKTDKEQS      
       :.  .:        
NP_002 ENRIRELTANLTFS
        330       340

>>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom  (338 aa)
 initn: 362 init1: 312 opt: 339  Z-score: 268.4  bits: 57.7 E(85289): 3.3e-08
Smith-Waterman score: 357; 34.5% identity (57.4% similar) in 235 aa overlap (30-254:116-328)

                10        20        30        40        50         
pF1KB8  MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSF-APK
                                     :..:   ::    :.:  .  :.  : ::.
NP_067 GGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPE
          90       100       110       120       130       140     

       60        70        80        90           100           110
pF1KB8 PAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYM----RTWLEPLSGAVSF----PSFP
       :    .  :: :        :.::    :: . ..    :. . : .:  .:    :. :
NP_067 P----VCAAPGP--------PHGPA---GAASNFYSAVGRNGILP-QGFDQFYEAAPGPP
             150                  160       170        180         

              120       130       140       150       160       170
pF1KB8 AGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKH
        .: .    : : :  ..    :. :.      :::      .: . :.  :.. .:. .
NP_067 FAGPQPP-PPPAPPQPEGAADKGDPRTGAGGGGGSP--CTKATPGSEPKGAAEGSGGDGE
     190        200       210       220         230       240      

               180       190       200       210       220         
pF1KB8 KEE-KADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVL
           .:  . :. .   .  . .:::::::::::  :::.::.::.:.....: ...:.:
NP_067 GPPGEAGAEKSSSA---VAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRML
        250       260          270       280       290       300   

     230       240       250       260    
pF1KB8 NLTERQVKIWFQNRRMKMKKMNKEKTDKEQS    
       :::.::::::::::::: ::.:...          
NP_067 NLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
           310       320       330        

>>NP_055027 (OMIM: 605559) homeobox protein Hox-C11 [Hom  (304 aa)
 initn: 345 init1: 304 opt: 335  Z-score: 266.1  bits: 57.1 E(85289): 4.4e-08
Smith-Waterman score: 337; 31.4% identity (55.8% similar) in 226 aa overlap (40-254:79-294)

      10        20        30        40        50        60         
pF1KB8 YYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAP-
                                     :::     ... ::  :    .      : 
NP_055 SFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPS
       50        60        70        80        90       100        

             70        80           90       100       110         
pF1KB8 ------VPSQSSVVYHPYGPQPHL---GADTRYMRTWLEPLSGAVSFPSFPAGGRHYALK
             . ...:   : .   ::    :  .   .. . : .    : .   ::      
NP_055 TVTEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGD----
      110       120       130       140       150       160        

     120       130        140       150       160       170        
pF1KB8 PDAYPGRRADC-GPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLD
       : : :     : : ::... :.   .:    : .:     . : ..  .:. . ...  .
NP_055 PPAEP----PCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKE
              170       180       190       200       210       220

      180       190       200       210       220       230        
pF1KB8 PSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKI
       :.. .:   .:  ::::::::.:.:  :::.::.::.:.....: ...:.::::.:::::
NP_055 PAKGAAP--NAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKI
                230       240       250       260       270        

      240       250       260    
pF1KB8 WFQNRRMKMKKMNKEKTDKEQS    
       :::::::: ::.....          
NP_055 WFQNRRMKEKKLSRDRLQYFSGNPLL
      280       290       300    

>>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A  (313 aa)
 initn: 355 init1: 310 opt: 324  Z-score: 257.8  bits: 55.6 E(85289): 1.3e-07
Smith-Waterman score: 350; 34.8% identity (54.0% similar) in 250 aa overlap (29-254:69-303)

                 10        20        30             40         50  
pF1KB8   MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAA-----RPSGLVP-DCSDFPS
                                     :::  :: .          ::  :: . ::
NP_005 SSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPS
       40        50        60        70        80        90        

             60            70        80          90       100      
pF1KB8 CSFAPKPAVFSTSWA----PVPSQSSVVYHPYGPQPHLGA--DTRYMRTWLEPLSGAVS-
        . .:  .. ..:      :.:. ::  :   : .  :    :  .  ..  : . : : 
NP_005 AAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSD
      100       110       120       130       140       150        

                110       120           130       140       150    
pF1KB8 FPS-------FPAGGRHYALKPDAYPGRRA----DCGPGEGRSYPDYMYGSPGELRDRAP
       .:.        ::.    :    :  :  :    : : : :    .   ..  . : : :
NP_005 YPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCR--ETAAAAEEKERRRRP
      160       170       180       190       200         210      

          160       170       180       190       200       210    
pF1KB8 QTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFN
       ..  :::..    : : :.::  . .         . ::::::::::::  :::.::.:.
NP_005 ESSSSPESS----SGHTEDKAGGSSG---------QRTRKKRCPYTKYQIRELEREFFFS
        220           230                240       250       260   

          220       230       240       250       260    
pF1KB8 MYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS    
       .:.....: ...:.::::.::::::::::::: ::.:...          
NP_005 VYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
           270       280       290       300       310   




260 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:29:15 2016 done: Fri Nov  4 16:29:16 2016
 Total Scan time:  5.820 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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