Result of FASTA (omim) for pF1KB8891
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8891, 211 aa
  1>>>pF1KB8891 211 - 211 aa - 211 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5706+/-0.000273; mu= 13.7894+/- 0.017
 mean_var=84.5843+/-16.798, 0's: 0 Z-trim(120.5): 27  B-trim: 211 in 1/57
 Lambda= 0.139453
 statistics sampled from 35781 (35810) to 35781 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.42), width:  16
 Scan time:  5.950

The best scores are:                                      opt bits E(85289)
NP_000505 (OMIM: 171300,209880,600837,613711) glia ( 211) 1441 298.7 4.7e-81
NP_001177397 (OMIM: 171300,209880,600837,613711) g ( 228) 1441 298.7   5e-81
XP_016864826 (OMIM: 171300,209880,600837,613711) P ( 185) 1097 229.4 2.9e-60
NP_954701 (OMIM: 171300,209880,600837,613711) glia ( 185) 1097 229.4 2.9e-60
NP_001177398 (OMIM: 171300,209880,600837,613711) g ( 202) 1097 229.4 3.1e-60
XP_011512332 (OMIM: 171300,209880,600837,613711) P ( 159) 1089 227.8 7.8e-60
NP_001265027 (OMIM: 171300,209880,600837,613711) g ( 159) 1089 227.8 7.8e-60
XP_011526343 (OMIM: 602018) PREDICTED: neurturin i ( 197)  336 76.3 3.7e-14
NP_004549 (OMIM: 602018) neurturin preproprotein [ ( 197)  336 76.3 3.7e-14
NP_476432 (OMIM: 603886) artemin isoform 1 preprop ( 220)  240 57.1 2.6e-08
NP_476431 (OMIM: 603886) artemin isoform 3 [Homo s ( 228)  240 57.1 2.7e-08
NP_001129687 (OMIM: 603886) artemin isoform 3 [Hom ( 228)  240 57.1 2.7e-08
NP_004149 (OMIM: 602921) persephin preproprotein [ ( 156)  230 54.9 8.2e-08


>>NP_000505 (OMIM: 171300,209880,600837,613711) glial ce  (211 aa)
 initn: 1441 init1: 1441 opt: 1441  Z-score: 1576.2  bits: 298.7 E(85289): 4.7e-81
Smith-Waterman score: 1441; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)

               10        20        30        40        50        60
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
              130       140       150       160       170       180

              190       200       210 
pF1KB8 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
       :::::::::::::::::::::::::::::::
NP_000 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
              190       200       210 

>>NP_001177397 (OMIM: 171300,209880,600837,613711) glial  (228 aa)
 initn: 1441 init1: 1441 opt: 1441  Z-score: 1575.7  bits: 298.7 E(85289): 5e-81
Smith-Waterman score: 1441; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:18-228)

                                10        20        30        40   
pF1KB8                  MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
                        :::::::::::::::::::::::::::::::::::::::::::
NP_001 MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB8 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB8 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
              130       140       150       160       170       180

           170       180       190       200       210 
pF1KB8 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
              190       200       210       220        

>>XP_016864826 (OMIM: 171300,209880,600837,613711) PREDI  (185 aa)
 initn: 1097 init1: 1097 opt: 1097  Z-score: 1202.9  bits: 229.4 E(85289): 2.9e-60
Smith-Waterman score: 1197; 87.2% identity (87.7% similar) in 211 aa overlap (1-211:1-185)

               10        20        30        40        50        60
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
       ::::::::::::::::::::::::                          .:::::::::
XP_016 MKLWDVVAVCLVLLHTASAFPLPA--------------------------ANMPEDYPDQ
               10        20                                  30    

               70        80        90       100       110       120
pF1KB8 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB8 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
          100       110       120       130       140       150    

              190       200       210 
pF1KB8 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
       :::::::::::::::::::::::::::::::
XP_016 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
          160       170       180     

>>NP_954701 (OMIM: 171300,209880,600837,613711) glial ce  (185 aa)
 initn: 1097 init1: 1097 opt: 1097  Z-score: 1202.9  bits: 229.4 E(85289): 2.9e-60
Smith-Waterman score: 1197; 87.2% identity (87.7% similar) in 211 aa overlap (1-211:1-185)

               10        20        30        40        50        60
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
       ::::::::::::::::::::::::                          .:::::::::
NP_954 MKLWDVVAVCLVLLHTASAFPLPA--------------------------ANMPEDYPDQ
               10        20                                  30    

               70        80        90       100       110       120
pF1KB8 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB8 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
          100       110       120       130       140       150    

              190       200       210 
pF1KB8 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
       :::::::::::::::::::::::::::::::
NP_954 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
          160       170       180     

>>NP_001177398 (OMIM: 171300,209880,600837,613711) glial  (202 aa)
 initn: 1097 init1: 1097 opt: 1097  Z-score: 1202.4  bits: 229.4 E(85289): 3.1e-60
Smith-Waterman score: 1197; 87.2% identity (87.7% similar) in 211 aa overlap (1-211:18-202)

                                10        20        30        40   
pF1KB8                  MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
                        ::::::::::::::::::::::::                   
NP_001 MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPA-------------------
               10        20        30        40                    

            50        60        70        80        90       100   
pF1KB8 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
              .::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------ANMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
                     50        60        70        80        90    

           110       120       130       140       150       160   
pF1KB8 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
          100       110       120       130       140       150    

           170       180       190       200       210 
pF1KB8 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
          160       170       180       190       200  

>>XP_011512332 (OMIM: 171300,209880,600837,613711) PREDI  (159 aa)
 initn: 1089 init1: 1089 opt: 1089  Z-score: 1195.2  bits: 227.8 E(85289): 7.8e-60
Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 159 aa overlap (53-211:1-159)

             30        40        50        60        70        80  
pF1KB8 PAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
                                             10        20        30

             90       100       110       120       130       140  
pF1KB8 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
               40        50        60        70        80        90

            150       160       170       180       190       200  
pF1KB8 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
              100       110       120       130       140       150

            210 
pF1KB8 HSAKRCGCI
       :::::::::
XP_011 HSAKRCGCI
                

>>NP_001265027 (OMIM: 171300,209880,600837,613711) glial  (159 aa)
 initn: 1089 init1: 1089 opt: 1089  Z-score: 1195.2  bits: 227.8 E(85289): 7.8e-60
Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 159 aa overlap (53-211:1-159)

             30        40        50        60        70        80  
pF1KB8 PAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
                                             10        20        30

             90       100       110       120       130       140  
pF1KB8 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
               40        50        60        70        80        90

            150       160       170       180       190       200  
pF1KB8 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
              100       110       120       130       140       150

            210 
pF1KB8 HSAKRCGCI
       :::::::::
NP_001 HSAKRCGCI
                

>>XP_011526343 (OMIM: 602018) PREDICTED: neurturin isofo  (197 aa)
 initn: 322 init1: 156 opt: 336  Z-score: 375.1  bits: 76.3 E(85289): 3.7e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (98-211:87-197)

        70        80        90       100       110       120       
pF1KB8 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
                                     :.:.  :...: : :     : :  ... :
XP_011 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
         60        70        80        90       100           110  

       130       140       150       160       170        180      
pF1KB8 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
       ..::::: . : ..::::.:.:.::  .::  :. : . :::  ..: .: :::: :..:
XP_011 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
            120       130       140       150       160       170  

        190       200       210 
pF1KB8 DLSFLDDNLVYHILRKHSAKRCGCI
       ..:::: .  :: ... ::..:.:.
XP_011 EVSFLDAHSRYHTVHELSARECACV
            180       190       

>>NP_004549 (OMIM: 602018) neurturin preproprotein [Homo  (197 aa)
 initn: 322 init1: 156 opt: 336  Z-score: 375.1  bits: 76.3 E(85289): 3.7e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (98-211:87-197)

        70        80        90       100       110       120       
pF1KB8 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
                                     :.:.  :...: : :     : :  ... :
NP_004 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
         60        70        80        90       100           110  

       130       140       150       160       170        180      
pF1KB8 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
       ..::::: . : ..::::.:.:.::  .::  :. : . :::  ..: .: :::: :..:
NP_004 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
            120       130       140       150       160       170  

        190       200       210 
pF1KB8 DLSFLDDNLVYHILRKHSAKRCGCI
       ..:::: .  :: ... ::..:.:.
NP_004 EVSFLDAHSRYHTVHELSARECACV
            180       190       

>>NP_476432 (OMIM: 603886) artemin isoform 1 preproprote  (220 aa)
 initn: 252 init1: 129 opt: 240  Z-score: 270.1  bits: 57.1 E(85289): 2.6e-08
Smith-Waterman score: 246; 30.2% identity (53.0% similar) in 215 aa overlap (3-211:23-219)

                                   10        20        30        40
pF1KB8                     MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGR
                             :: ..:. :.:: ...   : .. : : ::       :
NP_476 MELGLGGLSTLSHCPWPRQQPALWPTLAA-LALLSSVAEASLGSAPRSP-AP-------R
               10        20         30        40         50        

               50         60         70        80        90        
pF1KB8 RRAPFALSSDS-NMPEDYPDQF-DDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAA
       .  : .:.: . ..:     .. .          .:    :    ..:::   .: : :.
NP_476 EGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPAPPPPAPPSALPRG--GRAARAG
              60        70        80        90       100           

      100       110       120       130       140       150        
pF1KB8 NPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDK
       .:      : :.. .  ::: : .  . :  ::::... : . ::.:::::  :.. .: 
NP_476 GP------GSRARAAGARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDL
     110             120       130       140       150       160   

      160       170           180       190       200       210  
pF1KB8 ILKNLSRNRRLV----SDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI 
        : .:     :     :  :.: ::::  ..  .::.: : ... . . ::  :::. 
NP_476 SLASLLGAGALRPPPGSRPVSQPCCRPTRYEA-VSFMDVNSTWRTVDRLSATACGCLG
           170       180       190        200       210       220




211 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:22:27 2016 done: Fri Nov  4 16:22:27 2016
 Total Scan time:  5.950 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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