Result of FASTA (omim) for pF1KB8766
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8766, 225 aa
  1>>>pF1KB8766 225 - 225 aa - 225 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1093+/-0.000415; mu= 15.2515+/- 0.026
 mean_var=67.3764+/-14.577, 0's: 0 Z-trim(111.5): 94  B-trim: 1047 in 1/49
 Lambda= 0.156250
 statistics sampled from 19993 (20103) to 19993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.236), width:  16
 Scan time:  5.960

The best scores are:                                      opt bits E(85289)
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288)  376 93.7 3.4e-19
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289)  376 93.7 3.4e-19
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286)  232 61.2   2e-09
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304)  232 61.3 2.1e-09
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428)  232 61.4 2.8e-09
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428)  232 61.4 2.8e-09
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428)  232 61.4 2.8e-09
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428)  232 61.4 2.8e-09
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428)  232 61.4 2.8e-09
NP_955751 (OMIM: 607947) potassium channel regulat ( 229)  215 57.3 2.4e-08
NP_775876 (OMIM: 607947) potassium channel regulat ( 272)  215 57.4 2.8e-08
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234)  214 57.1 2.9e-08
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283)  214 57.2 3.3e-08
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283)  214 57.2 3.3e-08
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283)  214 57.2 3.3e-08
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283)  214 57.2 3.3e-08
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283)  214 57.2 3.3e-08
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325)  212 56.8 5.1e-08
XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347)  210 56.3 7.3e-08
NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234)  199 53.7   3e-07
NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290)  200 54.0   3e-07
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173)  197 53.2 3.2e-07
XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175)  197 53.2 3.2e-07
NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329)  200 54.1 3.4e-07
NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313)  198 53.6 4.4e-07
NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314)  198 53.6 4.4e-07
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257)  196 53.1 5.1e-07
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257)  196 53.1 5.1e-07
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257)  196 53.1 5.1e-07
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257)  196 53.1 5.1e-07
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265)  196 53.1 5.3e-07
XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226)  193 52.4 7.4e-07
NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263)  193 52.4 8.4e-07
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865)  196 53.4 1.4e-06
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220)  188 51.2 1.6e-06
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225)  188 51.2 1.6e-06
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249)  188 51.3 1.8e-06
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297)  188 51.3   2e-06
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315)  188 51.3 2.1e-06
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321)  188 51.4 2.1e-06
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328)  188 51.4 2.2e-06
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352)  188 51.4 2.3e-06
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352)  188 51.4 2.3e-06
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370)  188 51.4 2.4e-06
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813)  188 51.6 4.5e-06
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815)  188 51.6 4.5e-06
NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316)  175 48.4 1.6e-05
XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391)  175 48.5 1.9e-05
NP_004967 (OMIM: 176258,616187) potassium voltage- ( 511)  151 43.1   0.001
XP_011518382 (OMIM: 176258,616187) PREDICTED: pota ( 535)  151 43.2   0.001


>>NP_001161433 (OMIM: 611725,611726) BTB/POZ domain-cont  (288 aa)
 initn: 503 init1: 249 opt: 376  Z-score: 465.5  bits: 93.7 E(85289): 3.4e-19
Smith-Waterman score: 481; 39.1% identity (63.4% similar) in 238 aa overlap (4-224:52-288)

                                          10        20        30   
pF1KB8                            MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF
                                     :: ::.::   :: :.::: .  . :: ::
NP_001 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF
              30        40        50        60        70        80 

            40        50        60        70         80        90  
pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL
       :.     ::.:::.:::: .:.:  .:..::.:..:  ...  ::.:::.: : ::.. :
NP_001 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL
              90       100       110       120       130       140 

            100       110       120       130         140          
pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D
       :.:  . ::.: :. ::  .: :...:: .:..:: .:.   :: ... ::. . :    
NP_001 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT
             150        160       170       180       190       200

     150       160                 170       180       190         
pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF
        :   .:  :.      : ..:.      :.::::.:: :  ::.:::  :..:::  : 
NP_001 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD
              210       220       230       240       250       260

     200       210          220     
pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW
        .   .   .  :... .  :: : .:: 
NP_001 HQCIGVCDKHLVNHYYCKRPIYEFKITW 
              270       280         

>>NP_694578 (OMIM: 611725,611726) BTB/POZ domain-contain  (289 aa)
 initn: 518 init1: 249 opt: 376  Z-score: 465.5  bits: 93.7 E(85289): 3.4e-19
Smith-Waterman score: 496; 39.3% identity (63.6% similar) in 239 aa overlap (4-225:52-289)

                                          10        20        30   
pF1KB8                            MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF
                                     :: ::.::   :: :.::: .  . :: ::
NP_694 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF
              30        40        50        60        70        80 

            40        50        60        70         80        90  
pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL
       :.     ::.:::.:::: .:.:  .:..::.:..:  ...  ::.:::.: : ::.. :
NP_694 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL
              90       100       110       120       130       140 

            100       110       120       130         140          
pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D
       :.:  . ::.: :. ::  .: :...:: .:..:: .:.   :: ... ::. . :    
NP_694 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT
             150        160       170       180       190       200

     150       160                 170       180       190         
pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF
        :   .:  :.      : ..:.      :.::::.:: :  ::.:::  :..:::  : 
NP_694 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD
              210       220       230       240       250       260

     200       210          220     
pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW
        .   .   .  :... .  :: : .:::
NP_694 HQCIGVCDKHLVNHYYCKRPIYEFKITWW
              270       280         

>>XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (286 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 290.1  bits: 61.2 E(85289): 2e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (304 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 289.7  bits: 61.3 E(85289): 2.1e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (428 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 287.6  bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_006 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_006 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_006 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (428 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 287.6  bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (428 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 287.6  bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_005 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ domain-  (428 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 287.6  bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
XP_005 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>NP_065819 (OMIM: 613423) BTB/POZ domain-containing pro  (428 aa)
 initn: 157 init1: 115 opt: 232  Z-score: 287.6  bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)

                                     10        20        30        
pF1KB8                       MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
                                ::::::::. . :  .:: ..: : : .:::    
NP_065 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
               10        20        30        40        50        60

           40        50        60          70           80         
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
       .    . :..::::::: .  :: ::::::  ::  : .:.::   . :::.....  ::
NP_065 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
               70        80        90        100       110         

      90       100       110       120       130       140         
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
       :::                                                         
NP_065 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
     120       130       140       150       160       170         

>>NP_955751 (OMIM: 607947) potassium channel regulatory   (229 aa)
 initn: 212 init1: 165 opt: 215  Z-score: 270.8  bits: 57.3 E(85289): 2.4e-08
Smith-Waterman score: 215; 41.9% identity (71.0% similar) in 93 aa overlap (4-92:6-98)

                 10        20        30        40        50        
pF1KB8   MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRP
            .: :::::.. :: ..:...::.:.::.:...  .    . :..:.:: .  :  
NP_955 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
               10        20        30        40        50        60

       60          70          80        90       100       110    
pF1KB8 ILDYLRTGQV--PTQHIP--EVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPG
       :::.::: :.  ::.     .. ::: :::.. :: ::                      
NP_955 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KB8 YSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPW
                                                                   
NP_955 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
              130       140       150       160       170       180




225 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 15:24:28 2016 done: Fri Nov  4 15:24:29 2016
 Total Scan time:  5.960 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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