Result of FASTA (omim) for pF1KB8763
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8763, 211 aa
  1>>>pF1KB8763 211 - 211 aa - 211 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8432+/-0.000273; mu= 9.6786+/- 0.017
 mean_var=147.1309+/-29.938, 0's: 0 Z-trim(122.9): 61  B-trim: 0 in 0/61
 Lambda= 0.105736
 statistics sampled from 41652 (41713) to 41652 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.489), width:  16
 Scan time:  6.650

The best scores are:                                      opt bits E(85289)
NP_003736 (OMIM: 603597) suppressor of cytokine si ( 211) 1445 230.7 1.4e-60
NP_003946 (OMIM: 604176) suppressor of cytokine si ( 225)  284 53.6   3e-07
NP_001257398 (OMIM: 605117) suppressor of cytokine ( 198)  252 48.7   8e-06
NP_001257400 (OMIM: 605117) suppressor of cytokine ( 198)  252 48.7   8e-06
NP_001257396 (OMIM: 605117) suppressor of cytokine ( 198)  252 48.7   8e-06
NP_003868 (OMIM: 605117) suppressor of cytokine si ( 198)  252 48.7   8e-06
NP_001257399 (OMIM: 605117) suppressor of cytokine ( 198)  252 48.7   8e-06
NP_001257397 (OMIM: 605117) suppressor of cytokine ( 198)  252 48.7   8e-06
XP_016875645 (OMIM: 605117) PREDICTED: suppressor  ( 198)  252 48.7   8e-06
XP_011537238 (OMIM: 605117) PREDICTED: suppressor  ( 204)  252 48.7 8.2e-06
XP_011537237 (OMIM: 605117) PREDICTED: suppressor  ( 212)  252 48.7 8.4e-06
XP_011537231 (OMIM: 605117) PREDICTED: suppressor  ( 220)  252 48.7 8.6e-06
XP_016875644 (OMIM: 605117) PREDICTED: suppressor  ( 222)  252 48.7 8.7e-06
XP_016875637 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875639 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875638 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875640 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875643 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875641 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875642 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
XP_016875636 (OMIM: 605117) PREDICTED: suppressor  ( 243)  252 48.7 9.3e-06
NP_659508 (OMIM: 602441,607948,611162,614383) cyto ( 258)  227 45.0 0.00014
XP_011531631 (OMIM: 602441,607948,611162,614383) P ( 264)  227 45.0 0.00014
NP_037456 (OMIM: 602441,607948,611162,614383) cyto ( 275)  227 45.0 0.00014


>>NP_003736 (OMIM: 603597) suppressor of cytokine signal  (211 aa)
 initn: 1445 init1: 1445 opt: 1445  Z-score: 1208.7  bits: 230.7 E(85289): 1.4e-60
Smith-Waterman score: 1445; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)

               10        20        30        40        50        60
pF1KB8 MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 HADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQ
              130       140       150       160       170       180

              190       200       210 
pF1KB8 RIVATVGRENLARIPLNPVLRDYLSSFPFQI
       :::::::::::::::::::::::::::::::
NP_003 RIVATVGRENLARIPLNPVLRDYLSSFPFQI
              190       200       210 

>>NP_003946 (OMIM: 604176) suppressor of cytokine signal  (225 aa)
 initn: 294 init1: 215 opt: 284  Z-score: 251.2  bits: 53.6 E(85289): 3e-07
Smith-Waterman score: 284; 38.9% identity (64.9% similar) in 131 aa overlap (43-165:8-134)

             20        30        40        50          60        70
pF1KB8 VSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFR--TFRSHADYRRITRA
                                     ::.    : :: .:  :: :...:. .. :
NP_003                        MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNA
                                      10        20        30       

               80        90       100       110       120       130
pF1KB8 SALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHF
          :.  ::::. ..   :.  : :::.::::.::: ..  ::.::::  ::  ..:.. 
NP_003 VRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQC
        40        50        60        70        80        90       

              140             150       160       170       180    
pF1KB8 QAGRFHLDGSRES------FDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVA
       ..: : :... .:      :::...:..::.  :    :::                   
NP_003 EGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPP----GAPSFPSPPTEPSSEVPEQPSA
       100       110       120       130           140       150   

          190       200       210                                  
pF1KB8 TVGRENLARIPLNPVLRDYLSSFPFQI                                 
                                                                   
NP_003 QPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGP
           160       170       180       190       200       210   

>>NP_001257398 (OMIM: 605117) suppressor of cytokine sig  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_001 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_001 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_001 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_001 PLPTRLKDYLEEYKFQV
             190        

>>NP_001257400 (OMIM: 605117) suppressor of cytokine sig  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_001 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_001 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_001 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_001 PLPTRLKDYLEEYKFQV
             190        

>>NP_001257396 (OMIM: 605117) suppressor of cytokine sig  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_001 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_001 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_001 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_001 PLPTRLKDYLEEYKFQV
             190        

>>NP_003868 (OMIM: 605117) suppressor of cytokine signal  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_003 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_003 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_003 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_003 PLPTRLKDYLEEYKFQV
             190        

>>NP_001257399 (OMIM: 605117) suppressor of cytokine sig  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_001 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_001 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_001 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_001 PLPTRLKDYLEEYKFQV
             190        

>>NP_001257397 (OMIM: 605117) suppressor of cytokine sig  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
NP_001 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
NP_001 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
NP_001 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
NP_001 PLPTRLKDYLEEYKFQV
             190        

>>XP_016875645 (OMIM: 605117) PREDICTED: suppressor of c  (198 aa)
 initn: 318 init1: 223 opt: 252  Z-score: 225.5  bits: 48.7 E(85289): 8e-06
Smith-Waterman score: 299; 34.7% identity (61.1% similar) in 167 aa overlap (66-211:35-198)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
XP_016 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
XP_016 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
XP_016 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210 
pF1KB8 PLNPVLRDYLSSFPFQI
       ::   :.:::  . ::.
XP_016 PLPTRLKDYLEEYKFQV
             190        

>>XP_011537238 (OMIM: 605117) PREDICTED: suppressor of c  (204 aa)
 initn: 316 init1: 223 opt: 252  Z-score: 225.3  bits: 48.7 E(85289): 8.2e-06
Smith-Waterman score: 295; 34.9% identity (60.8% similar) in 166 aa overlap (66-210:35-197)

          40        50        60        70        80        90     
pF1KB8 PARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRA
                                     :...:   :   :.::: ..:. :.:.:. 
XP_011 CLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKE
           10        20        30        40        50        60    

         100       110       120       130            140          
pF1KB8 EPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDG-----SR-ESFDCLFE
        : ::::.::: . . ....::: ..:::..:...: :.:.::.     :. ..:: . .
XP_011 APEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVH
           70        80        90       100       110       120    

     150                 160            170       180       190    
pF1KB8 LLEHYVA----------APRR-----MLGAPLRQRRVRPLQELCRQRIVATVGRENLARI
       :...::           :::      .:  ::    .  ::.:::  :   .:   .  .
XP_011 LIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTS-APSLQHLCRLTINKCTG--AIWGL
          130       140       150        160       170         180 

          200       210       
pF1KB8 PLNPVLRDYLSSFPFQI      
       ::   :.:::  . ::       
XP_011 PLPTRLKDYLEEYKFQPAVFYPG
             190       200    




211 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 15:22:47 2016 done: Fri Nov  4 15:22:48 2016
 Total Scan time:  6.650 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com