Result of FASTA (omim) for pF1KB8726
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8726, 358 aa
  1>>>pF1KB8726 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.5442+/-0.000666; mu= -3.7667+/- 0.039
 mean_var=667.3320+/-158.026, 0's: 0 Z-trim(113.9): 1712  B-trim: 378 in 1/57
 Lambda= 0.049648
 statistics sampled from 21185 (23493) to 21185 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.275), width:  16
 Scan time:  8.100

The best scores are:                                      opt bits E(85289)
NP_443732 (OMIM: 610710) testis-specific serine/th ( 358) 2393 187.3 4.5e-47
NP_114417 (OMIM: 610709) testis-specific serine/th ( 367) 1597 130.3 6.6e-30
NP_443073 (OMIM: 607660) testis-specific serine/th ( 268)  893 79.7 8.6e-15
NP_114426 (OMIM: 610712) testis-specific serine/th ( 273)  818 74.3 3.6e-13
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734)  670 64.4 8.9e-10
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783)  670 64.5 9.2e-10
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765)  632 61.8   6e-09
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765)  632 61.8   6e-09
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765)  632 61.8   6e-09
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643)  630 61.5 6.1e-09
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708)  630 61.6 6.4e-09
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713)  630 61.6 6.4e-09
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722)  630 61.6 6.4e-09
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728)  630 61.6 6.5e-09
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729)  630 61.6 6.5e-09
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660)  629 61.4 6.5e-09
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737)  630 61.6 6.5e-09
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738)  630 61.6 6.5e-09
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739)  630 61.6 6.5e-09
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744)  630 61.6 6.5e-09
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753)  630 61.6 6.6e-09
NP_056006 (OMIM: 608973) serine/threonine-protein  ( 926)  629 61.7 7.6e-09
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709)  624 61.1 8.6e-09
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213)  629 61.9 8.7e-09
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719)  624 61.1 8.7e-09
NP_004945 (OMIM: 600526) serine/threonine-protein  ( 724)  624 61.1 8.7e-09
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729)  624 61.1 8.7e-09
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738)  624 61.2 8.8e-09
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739)  624 61.2 8.8e-09
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744)  624 61.2 8.8e-09
NP_059672 (OMIM: 600526) serine/threonine-protein  ( 745)  624 61.2 8.8e-09
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745)  624 61.2 8.8e-09
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261)  629 61.9 8.8e-09
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261)  629 61.9 8.8e-09
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753)  624 61.2 8.9e-09
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763)  624 61.2 8.9e-09
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309)  629 61.9   9e-09
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780)  624 61.2   9e-09
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781)  624 61.2   9e-09
NP_079440 (OMIM: 614776) serine/threonine-protein  (1321)  629 62.0   9e-09
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321)  629 62.0   9e-09
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784)  624 61.2   9e-09
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788)  624 61.2 9.1e-09
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788)  624 61.2 9.1e-09
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793)  624 61.2 9.1e-09
NP_061120 (OMIM: 606511) serine/threonine-protein  ( 795)  624 61.2 9.1e-09
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796)  624 61.2 9.1e-09
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798)  624 61.2 9.1e-09
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799)  624 61.2 9.1e-09
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808)  624 61.2 9.2e-09


>>NP_443732 (OMIM: 610710) testis-specific serine/threon  (358 aa)
 initn: 2393 init1: 2393 opt: 2393  Z-score: 966.1  bits: 187.3 E(85289): 4.5e-47
Smith-Waterman score: 2393; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)

               10        20        30        40        50        60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
              250       260       270       280       290       300

              310       320       330       340       350        
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
              310       320       330       340       350        

>>NP_114417 (OMIM: 610709) testis-specific serine/threon  (367 aa)
 initn: 1602 init1: 1566 opt: 1597  Z-score: 657.9  bits: 130.3 E(85289): 6.6e-30
Smith-Waterman score: 1597; 71.8% identity (89.4% similar) in 330 aa overlap (1-330:1-327)

               10        20        30        40        50        60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
       ::::.::...::..:::::.:::::::::::::::::::.:::::::.:.::.:.:::::
NP_114 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
       ..::: .:: :::::::::::: :..::.:::.:::::::.:: .:::::: ::: :.::
NP_114 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
       : :.:::::::.:::::::.:::::::::::::::.::::::::..::. :::::::: :
NP_114 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
       ::::::::.::::::::::::::::::::::::::::::.:.:::::::::::.:::::.
NP_114 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
       :: :::::::.::::::..:::::::::: :.:: : ... :.....:::..  .:    
NP_114 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP-KARGSPSVAINKEGESSRGTEPLWT
              250       260       270        280       290         

              310       320       330       340       350          
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST  
        . :   :..   ::  . . .  . ::..                              
NP_114 PEPG--SDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGP
     300         310       320       330       340       350       

>>NP_443073 (OMIM: 607660) testis-specific serine/threon  (268 aa)
 initn: 843 init1: 458 opt: 893  Z-score: 386.5  bits: 79.7 E(85289): 8.6e-15
Smith-Waterman score: 893; 47.4% identity (77.9% similar) in 272 aa overlap (1-272:1-265)

               10        20        30        40        50        60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
       :.:   : ..:: .: ..:.:.:.::: :.:.. . .::.:.::.   : .:..::::::
NP_443 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
       ..:. :..: .::..::..:..::.: ..:::.  ::... .   : : :. :. .:::.
NP_443 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
         :..:::   ..:::::::: :: . ::.::.::::.:  :  :. .  ::.:::::.:
NP_443 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK-VLPKSHRE--LSQTFCGSTA
      120       130       140        150        160         170    

              190       200       210       220       230       240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
       ::::::::.::.. :  :.::.::.::.:.:.:.:.::.:: :::  :... :.::   .
NP_443 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS
          180       190       200       210       220        230   

              250       260       270       280       290       300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
       .. .:.::. :.:.::.  :  :.:.  : ::                            
NP_443 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST                         
           240       250       260                                 

              310       320       330       340       350        
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST

>>NP_114426 (OMIM: 610712) testis-specific serine/threon  (273 aa)
 initn: 765 init1: 292 opt: 818  Z-score: 357.4  bits: 74.3 E(85289): 3.6e-13
Smith-Waterman score: 818; 46.4% identity (74.5% similar) in 274 aa overlap (1-273:1-268)

               10        20        30        40        50        60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
       :.   .: . :: .: ..:.:::.::: : :.. : .::.:..::...: :::..:::::
NP_114 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
       ..::  : :  :....:..:. .:..::.:: ..  :::. .. .: .    :: .: :.
NP_114 LSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQI
               70        80        90        100       110         

              130       140        150       160       170         
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFN-IKLSDFGFSKRCLRDSNGRIILSKTFCGSA
       ..::.: ::  .:::::::::.::. :   .::.::::.    :...:   :: :.::::
NP_114 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
     120       130       140       150           160       170     

     180       190       200       210       220       230         
pF1KB8 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSK
       :::.:::: .:::.:: ::.::.::.::.:: : ::.:::::  . : ::.  : .:.. 
NP_114 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
         180       190       200       210       220        230    

     240       250       260       270       280       290         
pF1KB8 NLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKL
       .:. .:: :: ..:: . : :    ..  . ::.                          
NP_114 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG                     
          240       250       260       270                        

     300       310       320       330       340       350        
pF1KB8 DTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST

>>XP_011527776 (OMIM: 605705,616341) PREDICTED: serine/t  (734 aa)
 initn: 621 init1: 267 opt: 670  Z-score: 296.5  bits: 64.4 E(85289): 8.9e-10
Smith-Waterman score: 670; 41.1% identity (68.4% similar) in 285 aa overlap (7-285:22-297)

                              10        20        30        40     
pF1KB8                MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDR
                            ::   : .  .::::..: :: :  .  : .::.::::.
XP_011 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 KKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQ
        .  .. .:..  ::....  .::  ::: :...::.:  .::. :.. .:......  .
XP_011 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
               70         80        90        100       110        

         110       120       130       140       150       160     
pF1KB8 GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDS
       : : :. ::: : :. :::.::::  ::::::: :::::: ...:::.::::..     .
XP_011 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYK
      120       130       140       150       160       170        

         170       180       190       200       210       220     
pF1KB8 NGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML
       .:. .  .:.:::  ::::::...  :.    :::::::.::..::::.:.:  ..  . 
XP_011 SGEPL--STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLR
         180         190       200       210       220       230   

         230       240       250       260       270               
pF1KB8 RIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL--QP--PKPK--A
       .   : :  .:    .. .:..:: :::  : ..:. : .: .: :.  .:  : :   :
XP_011 QRVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPA
           240         250       260       270       280       290 

     280       290       300       310       320       330         
pF1KB8 TSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAE
        :. :.                                                      
XP_011 FSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVEVPQEGLSTDPFRPALLCPQPQTLVQSV
             300       310       320       330       340       350 

>>NP_775490 (OMIM: 605705,616341) serine/threonine-prote  (783 aa)
 initn: 621 init1: 267 opt: 670  Z-score: 296.3  bits: 64.5 E(85289): 9.2e-10
Smith-Waterman score: 670; 41.1% identity (68.4% similar) in 285 aa overlap (7-285:22-297)

                              10        20        30        40     
pF1KB8                MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDR
                            ::   : .  .::::..: :: :  .  : .::.::::.
NP_775 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KB8 KKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQ
        .  .. .:..  ::....  .::  ::: :...::.:  .::. :.. .:......  .
NP_775 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
               70         80        90        100       110        

         110       120       130       140       150       160     
pF1KB8 GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDS
       : : :. ::: : :. :::.::::  ::::::: :::::: ...:::.::::..     .
NP_775 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYK
      120       130       140       150       160       170        

         170       180       190       200       210       220     
pF1KB8 NGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML
       .:. .  .:.:::  ::::::...  :.    :::::::.::..::::.:.:  ..  . 
NP_775 SGEPL--STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLR
         180         190       200       210       220       230   

         230       240       250       260       270               
pF1KB8 RIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL--QP--PKPK--A
       .   : :  .:    .. .:..:: :::  : ..:. : .: .: :.  .:  : :   :
NP_775 QRVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPA
           240         250       260       270       280       290 

     280       290       300       310       320       330         
pF1KB8 TSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAE
        :. :.                                                      
NP_775 FSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNA
             300       310       320       330       340       350 

>>NP_001094064 (OMIM: 612760) SNF-related serine/threoni  (765 aa)
 initn: 557 init1: 178 opt: 632  Z-score: 281.6  bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)

               10                20        30        40        50  
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
               :.::   :.:.     .::.: .: :: :       .::::.::. :  : .
NP_001     MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
                   10        20        30        40        50      

             60        70        80        90       100        110 
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
       .   : .:.  .  :.: .:.. ::...:.  ..:.:.:::  ::....: : . .:.::
NP_001 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
          60        70        80         90       100       110    

             120       130       140        150       160       170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
       .:.:.: :.  :..::: : .:::::: ::... .:.  .::.:::::..    . :. .
NP_001 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
          120       130       140       150       160          170 

              180       190       200       210       220       230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
          : ::: ::.:::.: .  :.  . :::::::::...:::. :.....  . : .  .
NP_001 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
               180       190       200       210       220         

              240       250       260       270         280        
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
        .   :  .... :::::: :::: : ..:  ..:: .: :::   :.:           
NP_001 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
     230         240       250       260       270       280       

      290       300       310       320       330       340        
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
                                                                   
NP_001 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
       290       300       310       320       330       340       

>>NP_060189 (OMIM: 612760) SNF-related serine/threonine-  (765 aa)
 initn: 557 init1: 178 opt: 632  Z-score: 281.6  bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)

               10                20        30        40        50  
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
               :.::   :.:.     .::.: .: :: :       .::::.::. :  : .
NP_060     MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
                   10        20        30        40        50      

             60        70        80        90       100        110 
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
       .   : .:.  .  :.: .:.. ::...:.  ..:.:.:::  ::....: : . .:.::
NP_060 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
          60        70        80         90       100       110    

             120       130       140        150       160       170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
       .:.:.: :.  :..::: : .:::::: ::... .:.  .::.:::::..    . :. .
NP_060 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
          120       130       140       150       160          170 

              180       190       200       210       220       230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
          : ::: ::.:::.: .  :.  . :::::::::...:::. :.....  . : .  .
NP_060 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
               180       190       200       210       220         

              240       250       260       270         280        
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
        .   :  .... :::::: :::: : ..:  ..:: .: :::   :.:           
NP_060 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
     230         240       250       260       270       280       

      290       300       310       320       330       340        
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
                                                                   
NP_060 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
       290       300       310       320       330       340       

>>XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ser  (765 aa)
 initn: 557 init1: 178 opt: 632  Z-score: 281.6  bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)

               10                20        30        40        50  
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
               :.::   :.:.     .::.: .: :: :       .::::.::. :  : .
XP_005     MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
                   10        20        30        40        50      

             60        70        80        90       100        110 
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
       .   : .:.  .  :.: .:.. ::...:.  ..:.:.:::  ::....: : . .:.::
XP_005 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
          60        70        80         90       100       110    

             120       130       140        150       160       170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
       .:.:.: :.  :..::: : .:::::: ::... .:.  .::.:::::..    . :. .
XP_005 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
          120       130       140       150       160          170 

              180       190       200       210       220       230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
          : ::: ::.:::.: .  :.  . :::::::::...:::. :.....  . : .  .
XP_005 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
               180       190       200       210       220         

              240       250       260       270         280        
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
        .   :  .... :::::: :::: : ..:  ..:: .: :::   :.:           
XP_005 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
     230         240       250       260       270       280       

      290       300       310       320       330       340        
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
                                                                   
XP_005 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
       290       300       310       320       330       340       

>>XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtubule  (643 aa)
 initn: 530 init1: 275 opt: 630  Z-score: 281.5  bits: 61.5 E(85289): 6.1e-09
Smith-Waterman score: 630; 40.3% identity (70.5% similar) in 258 aa overlap (18-272:62-307)

                            10        20        30        40       
pF1KB8              MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKK
                                     .:::..:::: :       .::.::::. .
XP_005 TSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ
              40        50        60        70        80        90 

         50        60        70        80        90       100      
pF1KB8 -TPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQG
        .::.. . :  ::. :.  .:: .:.: .:..:: .  .:.::: .  :......  .:
XP_005 LNPTSLQKLF--REVRIMKILNHPNIVKLFEVIET-EKTLYLIMEYASGGEVFDYLVAHG
             100         110       120        130       140        

        110       120       130       140       150       160      
pF1KB8 ALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSN
        ..:  ::. :::. :::.:::.  ::::::: :::::: :.:::..:::::..     .
XP_005 RMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT--VG
      150       160       170       180       190       200        

        170       180       190       200       210       220      
pF1KB8 GRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML-
       :..    :::::  :::::..:.  :.    :.:::::::: .: ::.:.: ......  
XP_005 GKL---DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRE
           210       220       230       240       250       260   

          230       240       250       260       270       280    
pF1KB8 RIQK-EHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSAS
       :. . ..:. :     .. .:..:. :.:  .  .:  ...:..  :.            
XP_005 RVLRGKYRIPF----YMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPF
           270           280       290       300       310         

          290       300       310       320       330       340    
pF1KB8 FKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAK
                                                                   
XP_005 VEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSS
     320       330       340       350       360       370         




358 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:58:29 2016 done: Fri Nov  4 14:58:30 2016
 Total Scan time:  8.100 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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