Result of FASTA (omim) for pF1KB8714
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8714, 443 aa
  1>>>pF1KB8714 443 - 443 aa - 443 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.6359+/-0.000515; mu= -22.7105+/- 0.032
 mean_var=756.2225+/-155.085, 0's: 0 Z-trim(124.7): 411  B-trim: 771 in 1/60
 Lambda= 0.046639
 statistics sampled from 46494 (46955) to 46494 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.551), width:  16
 Scan time: 11.060

The best scores are:                                      opt bits E(85289)
NP_597712 (OMIM: 608926) EMI domain-containing pro ( 443) 3265 234.5 4.3e-61
NP_001254824 (OMIM: 608926) EMI domain-containing  ( 441) 3241 232.9 1.3e-60
XP_005261385 (OMIM: 608926) PREDICTED: EMI domain- ( 445) 3120 224.7 3.7e-58
XP_005261386 (OMIM: 608926) PREDICTED: EMI domain- ( 417) 2153 159.6 1.4e-38
XP_011528171 (OMIM: 608926) PREDICTED: EMI domain- ( 460) 1883 141.5 4.3e-33
XP_011528177 (OMIM: 608926) PREDICTED: EMI domain- ( 307) 1738 131.6 2.9e-30
XP_011528176 (OMIM: 608926) PREDICTED: EMI domain- ( 397) 1738 131.7 3.4e-30
XP_016884078 (OMIM: 608926) PREDICTED: EMI domain- ( 397) 1738 131.7 3.4e-30
XP_011528173 (OMIM: 608926) PREDICTED: EMI domain- ( 434) 1738 131.7 3.6e-30
XP_011528170 (OMIM: 608926) PREDICTED: EMI domain- ( 462) 1738 131.8 3.8e-30
XP_011528178 (OMIM: 608926) PREDICTED: EMI domain- ( 283) 1720 130.3 6.2e-30
XP_011528175 (OMIM: 608926) PREDICTED: EMI domain- ( 420) 1597 122.2 2.5e-27
XP_011528174 (OMIM: 608926) PREDICTED: EMI domain- ( 423) 1469 113.6   1e-24
XP_011528172 (OMIM: 608926) PREDICTED: EMI domain- ( 438) 1436 111.4 4.8e-24
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715)  670 60.5   4e-08
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838)  670 60.5 4.2e-08
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838)  670 60.5 4.2e-08
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466)  637 58.2 1.7e-07
XP_016855830 (OMIM: 120326) PREDICTED: collagen al (1028)  613 56.4   4e-07
XP_016855829 (OMIM: 120326) PREDICTED: collagen al (1077)  613 56.5 4.1e-07
XP_011539030 (OMIM: 120326) PREDICTED: collagen al (1089)  613 56.5 4.1e-07
XP_011539029 (OMIM: 120326) PREDICTED: collagen al (1302)  613 56.5 4.7e-07
XP_011539028 (OMIM: 120326) PREDICTED: collagen al (1402)  613 56.6 4.9e-07
XP_011539026 (OMIM: 120326) PREDICTED: collagen al (1563)  613 56.6 5.3e-07
XP_011539025 (OMIM: 120326) PREDICTED: collagen al (1573)  613 56.6 5.3e-07
XP_005270538 (OMIM: 120326) PREDICTED: collagen al (1588)  613 56.6 5.4e-07
XP_011539024 (OMIM: 120326) PREDICTED: collagen al (1589)  613 56.6 5.4e-07
XP_016855828 (OMIM: 120326) PREDICTED: collagen al (1592)  613 56.6 5.4e-07
XP_016855827 (OMIM: 120326) PREDICTED: collagen al (1593)  613 56.6 5.4e-07
NP_001847 (OMIM: 120326) collagen alpha-1(XVI) cha (1604)  613 56.6 5.4e-07
XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289)  604 55.9 7.1e-07
XP_016870728 (OMIM: 608461,615155) PREDICTED: coll (1214)  603 55.8 7.1e-07
XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330)  604 55.9 7.2e-07
XP_011517446 (OMIM: 608461,615155) PREDICTED: coll (1352)  603 55.9 7.7e-07
XP_011517445 (OMIM: 608461,615155) PREDICTED: coll (1353)  603 55.9 7.7e-07
XP_011517444 (OMIM: 608461,615155) PREDICTED: coll (1401)  603 55.9 7.9e-07
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305)  600 55.7 8.6e-07
XP_011539019 (OMIM: 120260,600204,603932,614284) P ( 508)  586 54.3 8.7e-07
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418)  600 55.7 9.1e-07
XP_016871181 (OMIM: 120350,616720) PREDICTED: coll ( 651)  588 54.5 9.4e-07
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535)  600 55.7 9.6e-07
XP_016855822 (OMIM: 120260,600204,603932,614284) P ( 595)  586 54.4 9.7e-07
XP_011539018 (OMIM: 120260,600204,603932,614284) P ( 599)  586 54.4 9.7e-07
XP_011539017 (OMIM: 120260,600204,603932,614284) P ( 599)  586 54.4 9.7e-07
XP_016855821 (OMIM: 120260,600204,603932,614284) P ( 693)  586 54.4 1.1e-06
NP_542992 (OMIM: 120350,616720) collagen alpha-1(X ( 668)  585 54.4 1.1e-06
XP_016858786 (OMIM: 120131,203780) PREDICTED: coll (1651)  598 55.6 1.1e-06
XP_016871173 (OMIM: 120350,616720) PREDICTED: coll ( 680)  585 54.4 1.1e-06
XP_011508859 (OMIM: 120131,203780) PREDICTED: coll (1663)  598 55.6 1.1e-06
XP_016871182 (OMIM: 120350,616720) PREDICTED: coll ( 649)  584 54.3 1.1e-06


>>NP_597712 (OMIM: 608926) EMI domain-containing protein  (443 aa)
 initn: 3265 init1: 3265 opt: 3265  Z-score: 1217.8  bits: 234.5 E(85289): 4.3e-61
Smith-Waterman score: 3265; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 PGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLL
              370       380       390       400       410       420

              430       440   
pF1KB8 RGKRGGHATNYRIVAPRSRDERG
       :::::::::::::::::::::::
NP_597 RGKRGGHATNYRIVAPRSRDERG
              430       440   

>>NP_001254824 (OMIM: 608926) EMI domain-containing prot  (441 aa)
 initn: 2466 init1: 2466 opt: 3241  Z-score: 1209.1  bits: 232.9 E(85289): 1.3e-60
Smith-Waterman score: 3241; 99.5% identity (99.5% similar) in 443 aa overlap (1-443:1-441)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::  ::::::::::::
NP_001 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEE--ASSASLEPMWSG
               70        80        90       100         110        

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
      120       130       140       150       160       170        

              190       200       210       220       230       240
pF1KB8 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB8 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB8 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KB8 PGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLL
      360       370       380       390       400       410        

              430       440   
pF1KB8 RGKRGGHATNYRIVAPRSRDERG
       :::::::::::::::::::::::
NP_001 RGKRGGHATNYRIVAPRSRDERG
      420       430       440 

>>XP_005261385 (OMIM: 608926) PREDICTED: EMI domain-cont  (445 aa)
 initn: 2827 init1: 2827 opt: 3120  Z-score: 1165.0  bits: 224.7 E(85289): 3.7e-58
Smith-Waterman score: 3120; 95.3% identity (97.5% similar) in 446 aa overlap (1-443:1-445)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
              310       320       330       340       350       360

              370          380       390       400       410       
pF1KB8 PGPKGDPGEKSHWGEGLH---QLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTP
       :::::::::::::. .:.   : .  :..::.:: .::..:   ::::::::::::::::
XP_005 PGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAII-WPEPELGSGAGPAGTGTP
              370       380       390       400        410         

       420       430       440   
pF1KB8 SLLRGKRGGHATNYRIVAPRSRDERG
       ::::::::::::::::::::::::::
XP_005 SLLRGKRGGHATNYRIVAPRSRDERG
     420       430       440     

>>XP_005261386 (OMIM: 608926) PREDICTED: EMI domain-cont  (417 aa)
 initn: 2634 init1: 1859 opt: 2153  Z-score: 813.7  bits: 159.6 E(85289): 1.4e-38
Smith-Waterman score: 2875; 89.0% identity (91.3% similar) in 446 aa overlap (1-443:1-417)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_005 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEE--------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
                     ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 --------------GCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
                      110       120       130       140       150  

              190       200       210       220       230       240
pF1KB8 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAV
            160       170       180       190       200       210  

              250       260       270       280       290       300
pF1KB8 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGP
            220       230       240       250       260       270  

              310       320       330       340       350       360
pF1KB8 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGE
            280       290       300       310       320       330  

              370          380       390       400       410       
pF1KB8 PGPKGDPGEKSHWGEGLH---QLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTP
       :::::::::::::. .:.   : .  :..::.:: .::..:   ::::::::::::::::
XP_005 PGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAII-WPEPELGSGAGPAGTGTP
            340       350       360       370        380       390 

       420       430       440   
pF1KB8 SLLRGKRGGHATNYRIVAPRSRDERG
       ::::::::::::::::::::::::::
XP_005 SLLRGKRGGHATNYRIVAPRSRDERG
             400       410       

>>XP_011528171 (OMIM: 608926) PREDICTED: EMI domain-cont  (460 aa)
 initn: 1897 init1: 1865 opt: 1883  Z-score: 715.0  bits: 141.5 E(85289): 4.3e-33
Smith-Waterman score: 3221; 96.3% identity (96.3% similar) in 460 aa overlap (1-443:1-460)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
              130       140       150       160       170       180

              190                        200       210       220   
pF1KB8 GPPPAQGSPGDGGLQ-----------------DQVGAWGLPGPTGPKGDAGSRGPMGMRG
       :::::::::::::::                 ::::::::::::::::::::::::::::
XP_011 GPPPAQGSPGDGGLQGLPGAIESVRVPLLPRNDQVGAWGLPGPTGPKGDAGSRGPMGMRG
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB8 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB8 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KB8 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEP
              370       380       390       400       410       420

           410       420       430       440   
pF1KB8 ELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
       ::::::::::::::::::::::::::::::::::::::::
XP_011 ELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
              430       440       450       460

>>XP_011528177 (OMIM: 608926) PREDICTED: EMI domain-cont  (307 aa)
 initn: 1960 init1: 1427 opt: 1738  Z-score: 664.4  bits: 131.6 E(85289): 2.9e-30
Smith-Waterman score: 1974; 87.7% identity (90.9% similar) in 308 aa overlap (156-443:1-307)

         130       140       150       160       170       180     
pF1KB8 MALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLWGPPPA
                                     ::::::::::::::::::::::::::::::
XP_011                               MTMLTVIEQPVPPTPATPEDPAPLWGPPPA
                                             10        20        30

         190                        200       210       220        
pF1KB8 QGSPGDGGLQ-----------------DQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQ
       ::::::::::                 :::::::::::::::::::::::::::::::::
XP_011 QGSPGDGGLQGLPGAIESVRVPLLPRNDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQ
               40        50        60        70        80        90

      230       240       250       260       270       280        
pF1KB8 GPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNN
              100       110       120       130       140       150

      290       300       310       320       330       340        
pF1KB8 HWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGE
              160       170       180       190       200       210

      350       360       370          380       390       400     
pF1KB8 PGPQGSAGQRGEPGPKGDPGEKSHWGEGLH---QLREALKILAERVLILETMIGLYEPEL
       :::::::::::::::::::::::::. .:.   : .  :..::.:: .::..:   ::::
XP_011 PGPQGSAGQRGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAII-WPEPEL
              220       230       240       250       260          

         410       420       430       440   
pF1KB8 GSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
       ::::::::::::::::::::::::::::::::::::::
XP_011 GSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
     270       280       290       300       

>>XP_011528176 (OMIM: 608926) PREDICTED: EMI domain-cont  (397 aa)
 initn: 2575 init1: 1427 opt: 1738  Z-score: 663.1  bits: 131.7 E(85289): 3.4e-30
Smith-Waterman score: 2589; 90.5% identity (93.0% similar) in 398 aa overlap (66-443:1-397)

          40        50        60        70        80        90     
pF1KB8 WCSYVVTRTISCHVQNGTYLQRVLQNCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRC
                                     ::::::::::::::::::::::::::::::
XP_011                               MSCPGSSYRTVVRPTYKVMYKIVTAREWRC
                                             10        20        30

         100       110       120       130       140       150     
pF1KB8 CPGHSGVSCEEVAASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPGHSGVSCEEVAASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAK
               40        50        60        70        80        90

         160       170       180       190                         
pF1KB8 MTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQ-----------------DQV
       ::::::::::::::::::::::::::::::::::::::::                 :::
XP_011 MTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQGLPGAIESVRVPLLPRNDQV
              100       110       120       130       140       150

      200       210       220       230       240       250        
pF1KB8 GAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPP
              160       170       180       190       200       210

      260       270       280       290       300       310        
pF1KB8 GPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGS
              220       230       240       250       260       270

      320       330       340       350       360       370        
pF1KB8 PGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::. .:.
XP_011 PGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWAPSLQ
              280       290       300       310       320       330

         380       390       400       410       420       430     
pF1KB8 ---QLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVA
          : .  :..::.:: .::..:   ::::::::::::::::::::::::::::::::::
XP_011 SFLQQQAQLELLARRVTLLEAII-WPEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVA
              340       350        360       370       380         

         440   
pF1KB8 PRSRDERG
       ::::::::
XP_011 PRSRDERG
     390       

>>XP_016884078 (OMIM: 608926) PREDICTED: EMI domain-cont  (397 aa)
 initn: 2575 init1: 1427 opt: 1738  Z-score: 663.1  bits: 131.7 E(85289): 3.4e-30
Smith-Waterman score: 2589; 90.5% identity (93.0% similar) in 398 aa overlap (66-443:1-397)

          40        50        60        70        80        90     
pF1KB8 WCSYVVTRTISCHVQNGTYLQRVLQNCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRC
                                     ::::::::::::::::::::::::::::::
XP_016                               MSCPGSSYRTVVRPTYKVMYKIVTAREWRC
                                             10        20        30

         100       110       120       130       140       150     
pF1KB8 CPGHSGVSCEEVAASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGHSGVSCEEVAASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAK
               40        50        60        70        80        90

         160       170       180       190                         
pF1KB8 MTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQ-----------------DQV
       ::::::::::::::::::::::::::::::::::::::::                 :::
XP_016 MTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQGLPGAIESVRVPLLPRNDQV
              100       110       120       130       140       150

      200       210       220       230       240       250        
pF1KB8 GAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPP
              160       170       180       190       200       210

      260       270       280       290       300       310        
pF1KB8 GPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGS
              220       230       240       250       260       270

      320       330       340       350       360       370        
pF1KB8 PGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::. .:.
XP_016 PGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWAPSLQ
              280       290       300       310       320       330

         380       390       400       410       420       430     
pF1KB8 ---QLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVA
          : .  :..::.:: .::..:   ::::::::::::::::::::::::::::::::::
XP_016 SFLQQQAQLELLARRVTLLEAII-WPEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVA
              340       350        360       370       380         

         440   
pF1KB8 PRSRDERG
       ::::::::
XP_016 PRSRDERG
     390       

>>XP_011528173 (OMIM: 608926) PREDICTED: EMI domain-cont  (434 aa)
 initn: 2869 init1: 1427 opt: 1738  Z-score: 662.6  bits: 131.7 E(85289): 3.6e-30
Smith-Waterman score: 2831; 85.7% identity (87.9% similar) in 463 aa overlap (1-443:1-434)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_011 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEE--------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
                     ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --------------GCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
                      110       120       130       140       150  

              190                        200       210       220   
pF1KB8 GPPPAQGSPGDGGLQ-----------------DQVGAWGLPGPTGPKGDAGSRGPMGMRG
       :::::::::::::::                 ::::::::::::::::::::::::::::
XP_011 GPPPAQGSPGDGGLQGLPGAIESVRVPLLPRNDQVGAWGLPGPTGPKGDAGSRGPMGMRG
            160       170       180       190       200       210  

           230       240       250       260       270       280   
pF1KB8 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
            220       230       240       250       260       270  

           290       300       310       320       330       340   
pF1KB8 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
            280       290       300       310       320       330  

           350       360       370          380       390       400
pF1KB8 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLH---QLREALKILAERVLILETMIGL
       ::::::::::::::::::::::::::::::. .:.   : .  :..::.:: .::..:  
XP_011 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAII-W
            340       350       360       370       380       390  

              410       420       430       440   
pF1KB8 YEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
        ::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
             400       410       420       430    

>>XP_011528170 (OMIM: 608926) PREDICTED: EMI domain-cont  (462 aa)
 initn: 3062 init1: 1427 opt: 1738  Z-score: 662.3  bits: 131.8 E(85289): 3.8e-30
Smith-Waterman score: 3076; 91.8% identity (94.0% similar) in 463 aa overlap (1-443:1-462)

               10        20        30        40        50        60
pF1KB8 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEVAASSASLEPMWSG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLW
              130       140       150       160       170       180

              190                        200       210       220   
pF1KB8 GPPPAQGSPGDGGLQ-----------------DQVGAWGLPGPTGPKGDAGSRGPMGMRG
       :::::::::::::::                 ::::::::::::::::::::::::::::
XP_011 GPPPAQGSPGDGGLQGLPGAIESVRVPLLPRNDQVGAWGLPGPTGPKGDAGSRGPMGMRG
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB8 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTF
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB8 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGER
              310       320       330       340       350       360

           350       360       370          380       390       400
pF1KB8 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLH---QLREALKILAERVLILETMIGL
       ::::::::::::::::::::::::::::::. .:.   : .  :..::.:: .::..:  
XP_011 GLRGEPGPQGSAGQRGEPGPKGDPGEKSHWAPSLQSFLQQQAQLELLARRVTLLEAII-W
              370       380       390       400       410          

              410       420       430       440   
pF1KB8 YEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
        ::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
     420       430       440       450       460  




443 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:50:03 2016 done: Fri Nov  4 14:50:05 2016
 Total Scan time: 11.060 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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