Result of FASTA (omim) for pF1KB8665
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8665, 499 aa
  1>>>pF1KB8665 499 - 499 aa - 499 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3409+/-0.000346; mu= 20.1030+/- 0.022
 mean_var=93.3721+/-18.440, 0's: 0 Z-trim(115.8): 15  B-trim: 156 in 1/59
 Lambda= 0.132729
 statistics sampled from 26422 (26436) to 26422 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.31), width:  16
 Scan time: 10.520

The best scores are:                                      opt bits E(85289)
XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U ( 499) 3156 614.6 2.1e-175
NP_056444 (OMIM: 600138,606419) U4/U6 small nuclea ( 499) 3156 614.6 2.1e-175
NP_057018 (OMIM: 616742) nucleolar protein 58 [Hom ( 529)  427 92.0 4.4e-18
NP_006383 (OMIM: 614153,614154) nucleolar protein  ( 594)  399 86.7   2e-16


>>XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U6 sm  (499 aa)
 initn: 3156 init1: 3156 opt: 3156  Z-score: 3270.1  bits: 614.6 E(85289): 2.1e-175
Smith-Waterman score: 3156; 99.8% identity (100.0% similar) in 499 aa overlap (1-499:1-499)

               10        20        30        40        50        60
pF1KB8 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
              430       440       450       460       470       480

              490         
pF1KB8 SSMAEFLKVKGEKSGLMST
       :::::::::::::::::::
XP_006 SSMAEFLKVKGEKSGLMST
              490         

>>NP_056444 (OMIM: 600138,606419) U4/U6 small nuclear ri  (499 aa)
 initn: 3156 init1: 3156 opt: 3156  Z-score: 3270.1  bits: 614.6 E(85289): 2.1e-175
Smith-Waterman score: 3156; 99.8% identity (100.0% similar) in 499 aa overlap (1-499:1-499)

               10        20        30        40        50        60
pF1KB8 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 LSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
              430       440       450       460       470       480

              490         
pF1KB8 SSMAEFLKVKGEKSGLMST
       :::::::::::::::::::
NP_056 SSMAEFLKVKGEKSGLMST
              490         

>>NP_057018 (OMIM: 616742) nucleolar protein 58 [Homo sa  (529 aa)
 initn: 402 init1: 324 opt: 427  Z-score: 445.6  bits: 92.0 E(85289): 4.4e-18
Smith-Waterman score: 437; 23.6% identity (61.2% similar) in 381 aa overlap (92-471:161-521)

              70        80        90       100       110       120 
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
                                     .::.: .:  ....:::      :. :. .
NP_057 EPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWH
              140       150       160       170       180       190

             130       140       150       160       170       180 
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSE
       :::: ... . : : . ....:.   :   . .:...: . .   :...:  ..: ..::
NP_057 FPELGKIISDNLTYCKCLQKVGDR--KNYASAKLSELLPEEVEAEVKAAAEISMGTEVSE
              200       210         220       230       240        

             190       200       210       220       230       240 
pF1KB8 EELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNL
       :..  . . : ...:..  . ..:::...::  ::::.....:  ..:.... ::.: ::
NP_057 EDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNL
      250       260       270       280       290       300        

             250       260       270       280       290       300 
pF1KB8 SKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTL
       .:  : ....:::..  . ...:    :. : :::...: .  :  . : .:..::: .:
NP_057 AKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVL
      310       320       330       340       350       360        

             310       320       330       340       350       360 
pF1KB8 AARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRK
       : : :.: :.. . .: : . ..: .. .  :   .....     : .. .:   .   :
NP_057 AIRYDAFGEDSSSAMGVENRAKLEARL-RTLEDRGIRKISGTGKAL-AKTEKYEHKSEVK
      370       380       390        400       410        420      

             370       380        390       400       410       420
pF1KB8 MKERLGLTEIRKQANRMSFGEIE-EDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
         .  : . .   ... .. ... ::   :          :. ..... ..:.:  . ..
NP_057 TYDPSGDSTLPTCSKKRKIEQVDKEDEITEK---------KAKKAKIK-VKVEEEEEEKV
        430       440       450                460        470      

              430       440       450       460       470       480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
       ..  . ...:..   : :. :...  .        :  .  :..:.  .::         
NP_057 AEEEETSVKKKKK-RGKKKHIKEEPLSEEE-----PCTSTAIASPEKKKKKKKKRENED 
        480        490       500            510       520          

              490         
pF1KB8 SSMAEFLKVKGEKSGLMST

>>NP_006383 (OMIM: 614153,614154) nucleolar protein 56 [  (594 aa)
 initn: 388 init1: 295 opt: 399  Z-score: 415.9  bits: 86.7 E(85289): 2e-16
Smith-Waterman score: 410; 24.7% identity (63.0% similar) in 308 aa overlap (92-386:167-474)

              70        80        90       100       110       120 
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
                                     .:... .:  ......: .   .:. :. .
NP_006 TDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYH
        140       150       160       170       180       190      

             130       140       150        160       170          
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNN-ENLQQILTNATIMVVSVTAS-TTQGQQL
       :::: ... .   : : .. .::  .  ... :.:...  ...   . . :: ...:...
NP_006 FPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDI
        200       210       220       230       240       250      

     180       190       200       210       220       230         
pF1KB8 SEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLT
       :  .:  .:   . .. :.  .. .. :..:.:: .::.:: .:: ...:.... ::.::
NP_006 SAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLT
        260       270       280       290       300       310      

     240       250       260       270       280       290         
pF1KB8 NLSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKC
       ::.: :: ....:::..  . .... .  :. : :.:: ..       . . .: .: ::
NP_006 NLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKC
        320       330       340       350       360       370      

     300       310       320       330                  340        
pF1KB8 TLAARVDSFHESTEGKVGYELKDEIERKFDKWQ--EPP---------PVKQVKPLPAPLD
       ..:.:.: : :   .  : .:....:.... ..  : :          . :..   : . 
NP_006 SIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEIT
        380       390       400       410       420       430      

      350       360       370       380       390       400        
pF1KB8 GQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVR
        . .:.  .: .: :.::.   . .. :  :  :  :.                      
NP_006 RKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM
        440       450       460       470       480       490      

      410       420       430       440       450       460        
pF1KB8 QTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAA
                                                                   
NP_006 EDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGS
        500       510       520       530       540       550      




499 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:21:21 2016 done: Fri Nov  4 14:21:22 2016
 Total Scan time: 10.520 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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