Result of FASTA (omim) for
pF1KB8631
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8631, 464 aa
1>>>pF1KB8631 464 - 464 aa - 464 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0628+/-0.000387; mu= 13.9254+/- 0.024
mean_var=78.8284+/-15.655, 0's: 0 Z-trim(113.2): 53 B-trim: 0 in 0/54
Lambda= 0.144455
statistics sampled from 22400 (22453) to 22400 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.263), width: 16
Scan time: 7.980
The best scores are: opt bits E(85289)
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 3091 654.0 2.5e-187
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 3079 651.5 1.4e-186
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 2775 588.1 1.5e-167
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 2775 588.1 1.5e-167
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 2775 588.1 1.5e-167
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 2775 588.1 1.5e-167
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 2775 588.1 1.5e-167
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 1148 249.0 1.8e-65
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 605 135.9 2e-31
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 572 129.0 2.5e-29
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 539 122.3 8.2e-27
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 538 122.1 9.5e-27
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 538 122.1 9.5e-27
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 538 122.1 9.5e-27
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 526 119.6 5.4e-26
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 526 119.6 5.4e-26
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 525 119.4 6.2e-26
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 387 90.4 7.1e-18
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 387 90.6 1.7e-17
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 387 90.6 1.9e-17
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 344 81.5 5.5e-15
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 337 80.0 9.8e-15
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 331 78.8 3e-14
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 331 78.8 3.1e-14
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 331 78.8 3.1e-14
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 325 77.5 6.7e-14
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 319 76.2 1.3e-13
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 320 76.5 1.3e-13
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 319 76.3 1.8e-13
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 319 76.3 1.8e-13
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 319 76.3 1.8e-13
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 319 76.3 1.8e-13
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 308 73.9 6.5e-13
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 295 71.2 4e-12
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 291 70.4 7.5e-12
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 258 63.5 7.5e-10
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 231 57.8 3.3e-08
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 189 49.0 1.3e-05
XP_016879312 (OMIM: 600227) PREDICTED: cyclin-F is ( 446) 173 45.9 0.00028
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 165 44.1 0.00061
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 165 44.1 0.00061
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 165 44.1 0.0007
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 165 44.1 0.0007
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 165 44.1 0.0007
>>NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [Homo (464 aa)
initn: 3091 init1: 3091 opt: 3091 Z-score: 3484.2 bits: 654.0 E(85289): 2.5e-187
Smith-Waterman score: 3091; 99.8% identity (99.8% similar) in 464 aa overlap (1-464:1-464)
10 20 30 40 50 60
pF1KB8 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYE
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 CLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
430 440 450 460
>>NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo sap (465 aa)
initn: 2826 init1: 2826 opt: 3079 Z-score: 3470.7 bits: 651.5 E(85289): 1.4e-186
Smith-Waterman score: 3079; 99.6% identity (99.6% similar) in 465 aa overlap (1-464:1-465)
10 20 30 40 50
pF1KB8 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQ-PVESEAMHCSNPKSGVVLATVA
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_003 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKY
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_003 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
370 380 390 400 410 420
420 430 440 450 460
pF1KB8 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::::::::::::::::
NP_003 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
430 440 450 460
>>XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3129.0 bits: 588.1 E(85289): 1.5e-167
Smith-Waterman score: 2775; 99.8% identity (99.8% similar) in 421 aa overlap (44-464:1-421)
20 30 40 50 60 70
pF1KB8 FIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPL
::::::::::::::::::::::::::::::
XP_011 MHCSNPKSGVVLATVARGPDACQILTRAPL
10 20 30
80 90 100 110 120 130
pF1KB8 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
340 350 360 370 380 390
440 450 460
pF1KB8 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::
XP_011 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
400 410 420
>>NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3129.0 bits: 588.1 E(85289): 1.5e-167
Smith-Waterman score: 2775; 99.8% identity (99.8% similar) in 421 aa overlap (44-464:1-421)
20 30 40 50 60 70
pF1KB8 FIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPL
::::::::::::::::::::::::::::::
NP_001 MHCSNPKSGVVLATVARGPDACQILTRAPL
10 20 30
80 90 100 110 120 130
pF1KB8 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
340 350 360 370 380 390
440 450 460
pF1KB8 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::
NP_001 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
400 410 420
>>XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3129.0 bits: 588.1 E(85289): 1.5e-167
Smith-Waterman score: 2775; 99.8% identity (99.8% similar) in 421 aa overlap (44-464:1-421)
20 30 40 50 60 70
pF1KB8 FIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPL
::::::::::::::::::::::::::::::
XP_011 MHCSNPKSGVVLATVARGPDACQILTRAPL
10 20 30
80 90 100 110 120 130
pF1KB8 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
340 350 360 370 380 390
440 450 460
pF1KB8 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::
XP_011 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
400 410 420
>>XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3129.0 bits: 588.1 E(85289): 1.5e-167
Smith-Waterman score: 2775; 99.8% identity (99.8% similar) in 421 aa overlap (44-464:1-421)
20 30 40 50 60 70
pF1KB8 FIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPL
::::::::::::::::::::::::::::::
XP_011 MHCSNPKSGVVLATVARGPDACQILTRAPL
10 20 30
80 90 100 110 120 130
pF1KB8 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
340 350 360 370 380 390
440 450 460
pF1KB8 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::
XP_011 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
400 410 420
>>NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 2775 init1: 2775 opt: 2775 Z-score: 3129.0 bits: 588.1 E(85289): 1.5e-167
Smith-Waterman score: 2775; 99.8% identity (99.8% similar) in 421 aa overlap (44-464:1-421)
20 30 40 50 60 70
pF1KB8 FIGGWGEEYLSWEGPGLPDFVFQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPL
::::::::::::::::::::::::::::::
NP_001 MHCSNPKSGVVLATVARGPDACQILTRAPL
10 20 30
80 90 100 110 120 130
pF1KB8 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQ
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYI
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLL
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIP
340 350 360 370 380 390
440 450 460
pF1KB8 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
:::::::::::::::::::::::::::::::
NP_001 HRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
400 410 420
>>NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] (432 aa)
initn: 1065 init1: 699 opt: 1148 Z-score: 1296.3 bits: 249.0 E(85289): 1.8e-65
Smith-Waterman score: 1153; 51.6% identity (71.4% similar) in 409 aa overlap (71-463:39-432)
50 60 70 80 90 100
pF1KB8 SEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGI
::. :.: :..:..: . :. : :
NP_001 PATREAGSALLALQQTALQEDQENINPEKAAPV-QQPRTRAALAVLKS-GNPRGLAQQQR
10 20 30 40 50 60
110 120 130 140 150
pF1KB8 TRIRCYSGSENAFPPAGKKALP--DCGVQEPP-----KQ-GFDIYMDELEQGDRDSCSVR
. : : : :: : : :: :: .: :..:: :. . . .
NP_001 PKTRRV---------APLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAES
70 80 90 100 110
160 170 180 190 200
pF1KB8 EGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVI
. . ::. .. : : : . .: . :: .: :.. ..: : :
NP_001 QKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVS----VN
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB8 NVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLY
.: .: :.:. :::: :.. .::. :::::::::..::.:::::::::::::::. :::.
NP_001 EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLH
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB8 LAVNFLVRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLK
::::.. :::: :::::::::::::::::::::.:::::::: ::::::::::::.:.:.
NP_001 LAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLR
240 250 260 270 280 290
330 340 350 360 370 380
pF1KB8 MEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAKYVAELSLLEADPFLKYLPS
::::.::::.:::..::.:::: :: :..: . ..:.:: ...::::..:::.::::::
NP_001 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPS
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB8 LIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKY
.::.::: :: :::. . :::.: :::.: . ::: .::..:: :.. ::.:::::
NP_001 VIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKY
360 370 380 390 400 410
450 460
pF1KB8 KASKYLCVSLMEPPAVLLLQ
: ::: :::..:: .: :
NP_001 KNSKYHGVSLLNPPETLNL
420 430
>>NP_004692 (OMIM: 602755) G2/mitotic-specific cyclin-B2 (398 aa)
initn: 575 init1: 417 opt: 605 Z-score: 685.3 bits: 135.9 E(85289): 2e-31
Smith-Waterman score: 605; 39.3% identity (70.7% similar) in 270 aa overlap (189-455:112-379)
160 170 180 190 200 210
pF1KB8 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
.:: . :::.. . .. ..:...::::
NP_004 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB8 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLVRFLSC
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :... :::.
NP_004 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
150 160 170 180 190 200
280 290 300 310 320 330
pF1KB8 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
NP_004 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB8 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
NP_004 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
270 280 290 300 310
400 410 420 430 440 450
pF1KB8 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
NP_004 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
320 330 340 350 360 370
460
pF1KB8 EPPAVLLLQ
NP_004 PQLNSKAVKDLASPLIGRS
380 390
>>NP_114172 (OMIM: 123836) G2/mitotic-specific cyclin-B1 (433 aa)
initn: 508 init1: 393 opt: 572 Z-score: 647.5 bits: 129.0 E(85289): 2.5e-29
Smith-Waterman score: 572; 36.5% identity (69.2% similar) in 266 aa overlap (201-464:161-424)
180 190 200 210 220 230
pF1KB8 DLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAH
:.: .::...:: :::. : .. . .
NP_114 ETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPK
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB8 YMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLVRFLSCMSVLRGKLQLVGT
:. . ..: .::.::.::::.: ...: ::.:..:... ::.. : . :::::.
NP_114 YLLGR-EVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGV
200 210 220 230 240
300 310 320 330 340 350
pF1KB8 AAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY
.::..::::::.::::. .:...::.::::.:. .:: .:..: : : : .:: .
NP_114 TAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRA
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB8 LRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAF
. : :. ..::::. ::..:. : .... :: :::.::::: ... : :: .
NP_114 SKIGEVDVEQHTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDNGEWTPTLQHY
310 320 330 340 350 360
420 430 440 450 460
pF1KB8 TGYSLSEIVPCLSELHKAYLDIPH--RPQQAIREKYKASKYLCVSLMEPPAVLLLQ
.:. ..: ...: : . . . ......:: .::. .: . :.:
NP_114 LSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAK
370 380 390 400 410 420
NP_114 AVAKV
430
464 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:59:33 2016 done: Fri Nov 4 13:59:34 2016
Total Scan time: 7.980 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]