Result of FASTA (omim) for pF1KB8451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8451, 364 aa
  1>>>pF1KB8451 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.9947+/-0.000499; mu= -5.7868+/- 0.030
 mean_var=573.7319+/-127.776, 0's: 0 Z-trim(119.4): 1396  B-trim: 33 in 1/56
 Lambda= 0.053545
 statistics sampled from 31242 (33387) to 31242 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.391), width:  16
 Scan time:  9.260

The best scores are:                                      opt bits E(85289)
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 2425 202.4 1.3e-51
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1857 158.5 2.1e-38
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1821 155.8 1.4e-37
XP_011529008 (OMIM: 602898) PREDICTED: mitogen-act ( 256) 1720 147.7 2.7e-35
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 1651 142.7 1.4e-33
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 1592 138.1 3.1e-32
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 1509 131.5 2.3e-30
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 1509 131.5 2.4e-30
XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1509 131.6 2.5e-30
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 1485 129.8 9.5e-30
XP_016865789 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1473 128.8 1.7e-29
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 1458 127.6 3.5e-29
XP_016865793 (OMIM: 600289) PREDICTED: mitogen-act ( 258) 1405 123.4 5.7e-28
NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 1406 123.6 5.9e-28
XP_016865792 (OMIM: 600289) PREDICTED: mitogen-act ( 270) 1305 115.7 1.2e-25
XP_016865791 (OMIM: 600289) PREDICTED: mitogen-act ( 273) 1305 115.7 1.2e-25
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 1065 97.4 5.7e-20
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7   1e-19
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7   1e-19
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7   1e-19
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 1051 96.3 1.2e-19
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 1051 96.3 1.2e-19
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357)  998 92.2   2e-18
NP_001290181 (OMIM: 602399) mitogen-activated prot ( 357)  955 88.9   2e-17
NP_001310254 (OMIM: 601158) mitogen-activated prot ( 384)  954 88.8 2.2e-17
NP_620634 (OMIM: 601158) mitogen-activated protein ( 384)  954 88.8 2.2e-17
NP_001310250 (OMIM: 601158) mitogen-activated prot ( 384)  954 88.8 2.2e-17
NP_001310251 (OMIM: 601158) mitogen-activated prot ( 427)  954 88.9 2.3e-17
NP_001310259 (OMIM: 601158) mitogen-activated prot ( 427)  954 88.9 2.3e-17
NP_001310252 (OMIM: 601158) mitogen-activated prot ( 427)  954 88.9 2.3e-17
NP_001265476 (OMIM: 601158) mitogen-activated prot ( 427)  954 88.9 2.3e-17
NP_001310253 (OMIM: 601158) mitogen-activated prot ( 384)  945 88.1 3.5e-17
NP_001310256 (OMIM: 601158) mitogen-activated prot ( 384)  945 88.1 3.5e-17
NP_001310231 (OMIM: 601158) mitogen-activated prot ( 384)  945 88.1 3.5e-17
NP_001310255 (OMIM: 601158) mitogen-activated prot ( 384)  945 88.1 3.5e-17
NP_620637 (OMIM: 601158) mitogen-activated protein ( 427)  945 88.2 3.7e-17
NP_001310257 (OMIM: 601158) mitogen-activated prot ( 427)  945 88.2 3.7e-17
NP_001310260 (OMIM: 601158) mitogen-activated prot ( 427)  945 88.2 3.7e-17
NP_001310258 (OMIM: 601158) mitogen-activated prot ( 427)  945 88.2 3.7e-17
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863929 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  935 87.4   6e-17
XP_006714332 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  935 87.4 6.3e-17
XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  935 87.4 6.3e-17
XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  935 87.4 6.3e-17
XP_016863921 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  935 87.4 6.3e-17


>>NP_002742 (OMIM: 602898) mitogen-activated protein kin  (364 aa)
 initn: 2425 init1: 2425 opt: 2425  Z-score: 1047.5  bits: 202.4 E(85289): 1.3e-51
Smith-Waterman score: 2425; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
              310       320       330       340       350       360

           
pF1KB8 EIEQ
       ::::
NP_002 EIEQ
           

>>NP_620581 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1857 init1: 1857 opt: 1857  Z-score: 810.4  bits: 158.5 E(85289): 2.1e-38
Smith-Waterman score: 1857; 75.5% identity (91.7% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::  :  :::::::::.::::.: :.: :::::::::::.:.:..   .:::::::::::
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       :.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
        :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::. :.: ::::: ::.:::::  ::. .....: ::::::.::: .:::::::.:..::
NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
       .:::::::.:::::.::: :.:::.: :...  ..::: :::.::.:: ::         
NP_620 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
              310       320       330       340       350       360

           
pF1KB8 EIEQ

>>NP_001306 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1821 init1: 1821 opt: 1821  Z-score: 795.4  bits: 155.8 E(85289): 1.4e-37
Smith-Waterman score: 1821; 73.2% identity (91.5% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::  :  :::::::::.::::.: :.: :::::::::::.:.:..   .:::::::::::
NP_001 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       :.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_001 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
        :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_001 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::: :..::::.:.:.::..::...:
NP_001 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::   .. .. :..::.:::::  ::. .....: ::::::.::: .:::::::.:..::
NP_001 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
       .:::::::.:::::.::: :.:::.: :...  ..::: :::.::.:: ::         
NP_001 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
              310       320       330       340       350       360

           
pF1KB8 EIEQ

>>XP_011529008 (OMIM: 602898) PREDICTED: mitogen-activat  (256 aa)
 initn: 1720 init1: 1720 opt: 1720  Z-score: 754.7  bits: 147.7 E(85289): 2.7e-35
Smith-Waterman score: 1720; 100.0% identity (100.0% similar) in 256 aa overlap (109-364:1-256)

       80        90       100       110       120       130        
pF1KB8 KHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGL
                                     ::::::::::::::::::::::::::::::
XP_011                               MGADLNNIVKCQALSDEHVQFLVYQLLRGL
                                             10        20        30

      140       150       160       170       180       190        
pF1KB8 KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWM
               40        50        60        70        80        90

      200       210       220       230       240       250        
pF1KB8 HYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY
              100       110       120       130       140       150

      260       270       280       290       300       310        
pF1KB8 IQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEP
              160       170       180       190       200       210

      320       330       340       350       360    
pF1KB8 EAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
              220       230       240       250      

>>XP_011512612 (OMIM: 600289) PREDICTED: mitogen-activat  (401 aa)
 initn: 1631 init1: 1631 opt: 1651  Z-score: 724.0  bits: 142.7 E(85289): 1.4e-33
Smith-Waterman score: 1652; 71.8% identity (88.7% similar) in 337 aa overlap (24-351:56-392)

                      10        20         30        40            
pF1KB8        MSGPRAGFYRQELNKTVWEVPQRLQGLRP-VGSGAYGSVCS--------AYDA
                                     ::   : . .:  ..:::        :.:.
XP_011 PAPLLSVASSGRNFPRGRALLPLRALPVLHLQHPSPCTHAGMRSTVCSTQVRCESAAFDT
          30        40        50        60        70        80     

           50        60        70        80        90       100    
pF1KB8 RLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYL
       .   .::::::::::::.:::.:::::::::::.::::::::::::::: :.:.:..:::
XP_011 KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYL
          90       100       110       120       130       140     

          110       120       130       140       150       160    
pF1KB8 VTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCEL
       :: ::::::::::::: :.:.:::::.::.:::::::::: ::::::::::.::::::::
XP_011 VTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCEL
         150       160       170       180       190       200     

          170       180       190       200       210       220    
pF1KB8 RILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFP
       .::::::::..:.:::::::::::::::::::::::::::::::::::::::: :..:::
XP_011 KILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP
         210       220       230       240       250       260     

          230       240       250       260       270       280    
pF1KB8 GSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDL
       :.:.::::: :...::::. :.: ::::: ::.:::::  ::. .....: ::::::.::
XP_011 GTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDL
         270       280       290       300       310       320     

          290       300       310       320       330       340    
pF1KB8 LGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQE
       : .:::::::.:..::.:::::::.:::::.::: :.:::.: :...  ..::: :::.:
XP_011 LEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDE
         330       340       350       360       370       380     

          350       360    
pF1KB8 VLSFKPPEPPKPPGSLEIEQ
       :.:: ::             
XP_011 VISFVPPPLDQEEMES    
         390       400     

>>NP_002960 (OMIM: 602399) mitogen-activated protein kin  (367 aa)
 initn: 1586 init1: 1586 opt: 1592  Z-score: 699.7  bits: 138.1 E(85289): 3.1e-32
Smith-Waterman score: 1592; 63.6% identity (88.4% similar) in 354 aa overlap (1-351:1-354)

                  10        20        30        40        50       
pF1KB8 MSGP---RAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSR
       ::.:   :.::::::..::.:::    . :.::::::::.:::: :.:   :::.::: :
NP_002 MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYR
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB8 PFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIV
       :::: . :.:.:::::::::..:::::::::::::  ...::.. :::  .::.::....
NP_002 PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB8 KCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADE
       : . :.....::::::.:.::.:::.::::::::::.:.::::::::.::::::::::: 
NP_002 KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB8 EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIME
       ::::::.::::::::..::::.:.::::::::::::::.. ::.:: :::..::::.::.
NP_002 EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB8 VVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRV
       :.:::  : . ...:..:..:...:: . .::..::. .:.:::..:: .:::::..:::
NP_002 VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB8 SAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPP
       .:.::::: :: . :: ::::... ::.: .  .:::.:::..::.::::::::      
NP_002 TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
              310       320       330       340       350       360

       360    
pF1KB8 GSLEIEQ
              
NP_002 VSKETPL
              

>>NP_620582 (OMIM: 600289) mitogen-activated protein kin  (297 aa)
 initn: 1509 init1: 1509 opt: 1509  Z-score: 666.0  bits: 131.5 E(85289): 2.3e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::  :  :::::::::.::::.: :.: :::::::::::.:.:..   .:::::::::::
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       :.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
        :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::. :.: ::::: ::.:::::  ::. .....: :::::                    
NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI   
              250       260       270       280       290          

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL

>>XP_016865790 (OMIM: 600289) PREDICTED: mitogen-activat  (301 aa)
 initn: 1509 init1: 1509 opt: 1509  Z-score: 665.9  bits: 131.5 E(85289): 2.4e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::  :  :::::::::.::::.: :.: :::::::::::.:.:..   .:::::::::::
XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       :.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
        :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::. :.: ::::: ::.:::::  ::. .....: :::::                    
XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
                                                                   
XP_016 K                                                           
                                                                   

>>XP_016865788 (OMIM: 600289) PREDICTED: mitogen-activat  (328 aa)
 initn: 1509 init1: 1509 opt: 1509  Z-score: 665.5  bits: 131.6 E(85289): 2.5e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)

               10        20        30        40        50        60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
       ::  :  :::::::::.::::.: :.: :::::::::::.:.:..   .:::::::::::
XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
       :.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
        :.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
       ::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
       ::. :.: ::::: ::.:::::  ::. .....: :::::                    
XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
                                                                   
XP_016 KCQHSRDCPRHEGELGLHISCTQTEMQR                                
              310       320                                        

>>NP_002745 (OMIM: 602899) mitogen-activated protein kin  (365 aa)
 initn: 1362 init1: 908 opt: 1485  Z-score: 655.1  bits: 129.8 E(85289): 9.5e-30
Smith-Waterman score: 1485; 60.5% identity (86.2% similar) in 347 aa overlap (5-350:6-351)

                10        20        30        40        50         
pF1KB8  MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPF
            . :::.:..:::.::.:.   .   :::::::::::: : :  .:::.:::::::
NP_002 MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 QSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKC
       :: : :.:.:::: ::::..::::::::::::::.:...: . :::  .: .::..:.  
NP_002 QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM
       . .:.:..:.::::.:.:::::::::..::::::.:.::::::::.::::::::.:: ::
NP_002 E-FSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM
               130       140       150       160       170         

     180       190       200       210       220       230         
pF1KB8 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVV
       ::::.::::::::..:.:::::::::::::::::::.: ::.:: :.::.::: .:..:.
NP_002 TGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVT
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KB8 GTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSA
       :.:. : . :.... :..::::::  :.::....:  :.: : ::: .:: :: :.:..:
NP_002 GVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTA
     240       250       260       270       280       290         

     300       310       320        330       340       350        
pF1KB8 AEALAHAYFSQYHDPEDEPEAE-PYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPG
       :.::.: .:  ..:::.: ::. :.:.:.: .. :..:::.  :.:...:.:        
NP_002 AQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRR
     300       310       320       330       340       350         

      360    
pF1KB8 SLEIEQ
             
NP_002 RSGMKL
     360     




364 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 13:01:04 2016 done: Fri Nov  4 13:01:06 2016
 Total Scan time:  9.260 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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