Result of FASTA (omim) for pF1KB8448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8448, 445 aa
  1>>>pF1KB8448 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0493+/-0.000278; mu= 15.1607+/- 0.018
 mean_var=82.6936+/-16.951, 0's: 0 Z-trim(120.1): 69  B-trim: 1907 in 1/53
 Lambda= 0.141039
 statistics sampled from 34791 (34860) to 34791 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.409), width:  16
 Scan time:  9.720

The best scores are:                                      opt bits E(85289)
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 2987 616.9 3.3e-176
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 2987 616.9 3.3e-176
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1454 305.0 2.6e-82
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 1454 305.0 2.6e-82
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1454 305.0 2.6e-82
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 1441 302.3 1.6e-81
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 1441 302.4 1.9e-81
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 1388 291.5 2.8e-78
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 1304 274.5   4e-73
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1087 230.3 7.5e-60
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1087 230.3 7.5e-60
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1087 230.3 7.5e-60
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 1061 225.0   3e-58
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1061 225.0   3e-58
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1061 225.0   3e-58
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1061 225.0   3e-58
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1046 222.0 2.5e-57
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 1024 217.5 5.1e-56
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 1024 217.5 5.8e-56
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501)  951 202.7 1.9e-51
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390)  885 189.2 1.7e-47
NP_001159762 (OMIM: 125853,600937,601820,606176,61 ( 303)  869 185.9 1.3e-46
XP_006718289 (OMIM: 125853,600937,601820,606176,61 ( 303)  869 185.9 1.3e-46
XP_016873169 (OMIM: 125853,600937,601820,606176,61 ( 303)  869 185.9 1.3e-46
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372)  850 182.0 2.2e-45
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372)  850 182.0 2.2e-45
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372)  850 182.0 2.2e-45
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389)  850 182.1 2.3e-45
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391)  850 182.1 2.3e-45
NP_001257351 (OMIM: 605722) inward rectifier potas ( 418)  824 176.8 9.7e-44
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418)  824 176.8 9.7e-44
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418)  824 176.8 9.7e-44
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418)  824 176.8 9.7e-44
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418)  824 176.8 9.7e-44
XP_006721950 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
XP_016880100 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
NP_061128 (OMIM: 605722) inward rectifier potassiu ( 453)  824 176.8   1e-43
XP_016880101 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
XP_006721949 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
XP_005257394 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
XP_016880098 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
NP_733937 (OMIM: 605722) inward rectifier potassiu ( 453)  824 176.8   1e-43
NP_733938 (OMIM: 605722) inward rectifier potassiu ( 453)  824 176.8   1e-43
XP_016880099 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
XP_006721948 (OMIM: 605722) PREDICTED: inward rect ( 453)  824 176.8   1e-43
NP_001278551 (OMIM: 605722) inward rectifier potas ( 453)  824 176.8   1e-43
NP_001278552 (OMIM: 605722) inward rectifier potas ( 453)  824 176.8   1e-43
NP_001247438 (OMIM: 601534) G protein-activated in ( 308)  735 158.6 2.1e-38
NP_002232 (OMIM: 274600,600791,602208,612780) ATP- ( 379)  716 154.8 3.7e-37
NP_001263367 (OMIM: 602106) ATP-sensitive inward r ( 375)  694 150.3 8.1e-36


>>NP_690607 (OMIM: 600504) inward rectifier potassium ch  (445 aa)
 initn: 2987 init1: 2987 opt: 2987  Z-score: 3284.5  bits: 616.9 E(85289): 3.3e-176
Smith-Waterman score: 2987; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)

               10        20        30        40        50        60
pF1KB8 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
              370       380       390       400       410       420

              430       440     
pF1KB8 SHLDLERMQASLPLDNISYRRESAI
       :::::::::::::::::::::::::
NP_690 SHLDLERMQASLPLDNISYRRESAI
              430       440     

>>NP_004972 (OMIM: 600504) inward rectifier potassium ch  (445 aa)
 initn: 2987 init1: 2987 opt: 2987  Z-score: 3284.5  bits: 616.9 E(85289): 3.3e-176
Smith-Waterman score: 2987; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)

               10        20        30        40        50        60
pF1KB8 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFG
              370       380       390       400       410       420

              430       440     
pF1KB8 SHLDLERMQASLPLDNISYRRESAI
       :::::::::::::::::::::::::
NP_004 SHLDLERMQASLPLDNISYRRESAI
              430       440     

>>XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 1893 init1: 1359 opt: 1454  Z-score: 1598.8  bits: 305.0 E(85289): 2.6e-82
Smith-Waterman score: 1846; 65.0% identity (82.5% similar) in 440 aa overlap (7-445:33-433)

                                       10        20        30      
pF1KB8                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                     ::..:. ::. ::::::::::::. :::..
XP_005 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
             10        20        30         40        50        60 

         40        50        60        70        80        90      
pF1KB8 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
XP_005 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
              70        80        90       100       110           

        100       110       120       130       140       150      
pF1KB8 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
XP_005 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
             120             130       140       150       160     

        160       170       180       190       200       210      
pF1KB8 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
XP_005 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
         170       180       190       200       210       220     

        220       230       240       250       260       270      
pF1KB8 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
XP_005 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
         230       240       250       260       270       280     

        280       290       300       310       320       330      
pF1KB8 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
       ..::..:::::::::::::::::::::::::::.:::::::::::.::::..::.:::.:
XP_005 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHF
         290       300       310       320       330       340     

        340       350       360       370       380       390      
pF1KB8 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
       :::::: .:: :::..: :.:. .     :  ..::::::::..:..::. : ..   . 
XP_005 HKTYEVPSTPRCSAKDLVENKFLL-----PSANSFCYENELAFLSRDEED-EADGDQDGR
         350       360            370       380       390          

        400       410       420       430        440     
pF1KB8 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
          ::. .:                : :..:.::.   :..  ::::: :
XP_005 SRDGLSPQA---------------RH-DFDRLQAGGGVLEQRPYRRESEI
     400                      410        420       430   

>>NP_066292 (OMIM: 602323) ATP-sensitive inward rectifie  (433 aa)
 initn: 1893 init1: 1359 opt: 1454  Z-score: 1598.8  bits: 305.0 E(85289): 2.6e-82
Smith-Waterman score: 1846; 65.0% identity (82.5% similar) in 440 aa overlap (7-445:33-433)

                                       10        20        30      
pF1KB8                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                     ::..:. ::. ::::::::::::. :::..
NP_066 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
             10        20        30         40        50        60 

         40        50        60        70        80        90      
pF1KB8 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
NP_066 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
              70        80        90       100       110           

        100       110       120       130       140       150      
pF1KB8 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
NP_066 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
             120             130       140       150       160     

        160       170       180       190       200       210      
pF1KB8 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_066 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
         170       180       190       200       210       220     

        220       230       240       250       260       270      
pF1KB8 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_066 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
         230       240       250       260       270       280     

        280       290       300       310       320       330      
pF1KB8 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
       ..::..:::::::::::::::::::::::::::.:::::::::::.::::..::.:::.:
NP_066 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHF
         290       300       310       320       330       340     

        340       350       360       370       380       390      
pF1KB8 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
       :::::: .:: :::..: :.:. .     :  ..::::::::..:..::. : ..   . 
NP_066 HKTYEVPSTPRCSAKDLVENKFLL-----PSANSFCYENELAFLSRDEED-EADGDQDGR
         350       360            370       380       390          

        400       410       420       430        440     
pF1KB8 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
          ::. .:                : :..:.::.   :..  ::::: :
NP_066 SRDGLSPQA---------------RH-DFDRLQAGGGVLEQRPYRRESEI
     400                      410        420       430   

>>XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 1893 init1: 1359 opt: 1454  Z-score: 1598.8  bits: 305.0 E(85289): 2.6e-82
Smith-Waterman score: 1846; 65.0% identity (82.5% similar) in 440 aa overlap (7-445:33-433)

                                       10        20        30      
pF1KB8                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                     ::..:. ::. ::::::::::::. :::..
XP_011 AASRANPYSIVSSEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIEFANMD
             10        20        30         40        50        60 

         40        50        60        70        80        90      
pF1KB8 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
XP_011 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLE--------
              70        80        90       100       110           

        100       110       120       130       140       150      
pF1KB8 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::::.::. ::.:
XP_011 --PAEGRGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQ
             120             130       140       150       160     

        160       170       180       190       200       210      
pF1KB8 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
XP_011 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
         170       180       190       200       210       220     

        220       230       240       250       260       270      
pF1KB8 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
XP_011 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
         230       240       250       260       270       280     

        280       290       300       310       320       330      
pF1KB8 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
       ..::..:::::::::::::::::::::::::::.:::::::::::.::::..::.:::.:
XP_011 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHF
         290       300       310       320       330       340     

        340       350       360       370       380       390      
pF1KB8 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
       :::::: .:: :::..: :.:. .     :  ..::::::::..:..::. : ..   . 
XP_011 HKTYEVPSTPRCSAKDLVENKFLL-----PSANSFCYENELAFLSRDEED-EADGDQDGR
         350       360            370       380       390          

        400       410       420       430        440     
pF1KB8 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLP-LDNISYRRESAI
          ::. .:                : :..:.::.   :..  ::::: :
XP_011 SRDGLSPQA---------------RH-DFDRLQAGGGVLEQRPYRRESEI
     400                      410        420       430   

>>NP_001181887 (OMIM: 613236,613239) inward rectifier po  (433 aa)
 initn: 1882 init1: 1345 opt: 1441  Z-score: 1584.6  bits: 302.3 E(85289): 1.6e-81
Smith-Waterman score: 1823; 70.8% identity (88.2% similar) in 380 aa overlap (7-386:33-390)

                                       10        20        30      
pF1KB8                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                     ::..:. ::. ::::::::::::. :::..
NP_001 AASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIAFANMD
             10        20        30         40        50        60 

         40        50        60        70        80        90      
pF1KB8 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
NP_001 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLE--------
              70        80        90       100       110           

        100       110       120       130       140       150      
pF1KB8 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::: .::. ::.:
NP_001 --PAEGHGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQ
             120             130       140       150       160     

        160       170       180       190       200       210      
pF1KB8 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
NP_001 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
         170       180       190       200       210       220     

        220       230       240       250       260       270      
pF1KB8 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
NP_001 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
         230       240       250       260       270       280     

        280       290       300       310       320       330      
pF1KB8 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
       ..::..:::::::::::::::::::::::::::.:::::::::::.::::..::.:::.:
NP_001 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHF
         290       300       310       320       330       340     

        340       350       360       370       380       390      
pF1KB8 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
       :::::: .:: :::..: :.:. .     :  ..::::::::..:..::.          
NP_001 HKTYEVPSTPRCSAKDLVENKFLL-----PSANSFCYENELAFLSRDEEDEADGDQDGRS
         350       360            370       380       390       400

        400       410       420       430       440     
pF1KB8 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI
                                                        
NP_001 RDGLSPQARHDFDRLQAGGGVLEQRPYRRGSEI                
              410       420       430                   

>>XP_005276976 (OMIM: 613236,613239) PREDICTED: inward r  (535 aa)
 initn: 1854 init1: 1345 opt: 1441  Z-score: 1583.1  bits: 302.4 E(85289): 1.9e-81
Smith-Waterman score: 1823; 70.8% identity (88.2% similar) in 380 aa overlap (7-386:135-492)

                                       10        20        30      
pF1KB8                         MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLS
                                     ::..:. ::. ::::::::::::. :::..
XP_005 AASRANPYSIVSLEEDGLHLVTMSGANGFGNGKVHT-RRRCRNRFVKKNGQCNIAFANMD
          110       120       130       140        150       160   

         40        50        60        70        80        90      
pF1KB8 NKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAA
       .:::::.::.:::::: ::::::.::: :::.:::.::..:: ::  :::::        
XP_005 EKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLE--------
           170       180       190       200       210             

        100       110       120       130       140       150      
pF1KB8 GGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQ
         :: : : .      ::.:.:.::..:::::.:::::::::.::::::: .::. ::.:
XP_005 --PAEGHGRT------PCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFMVVAQ
           220             230       240       250       260       

        160       170       180       190       200       210      
pF1KB8 SIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVE
       :::::.:::::::.:::::::::::::::::::.::...:::::::::::::::::::::
XP_005 SIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVE
       270       280       290       300       310       320       

        220       230       240       250       260       270      
pF1KB8 AHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGK
       :::::::::: .:.::::.:::: :..::.: ::::::::::: :.::::: :::.:...
XP_005 AHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISR
       330       340       350       360       370       380       

        280       290       300       310       320       330      
pF1KB8 EELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRF
       ..::..:::::::::::::::::::::::::::.:::::::::::.::::..::.:::.:
XP_005 QDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHF
       390       400       410       420       430       440       

        340       350       360       370       380       390      
pF1KB8 HKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAA
       :::::: .:: :::..: :.:. .     :  ..::::::::..:..::.          
XP_005 HKTYEVPSTPRCSAKDLVENKFLL-----PSANSFCYENELAFLSRDEEDEADGDQDGRS
       450       460       470            480       490       500  

        400       410       420       430       440     
pF1KB8 VAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI
                                                        
XP_005 RDGLSPQARHDFDRLQAGGGVLEQRPYRRGSEI                
            510       520       530                     

>>NP_000882 (OMIM: 170390,600681,609622,613980) inward r  (427 aa)
 initn: 1763 init1: 1283 opt: 1388  Z-score: 1526.4  bits: 291.5 E(85289): 2.8e-78
Smith-Waterman score: 1716; 60.9% identity (79.1% similar) in 440 aa overlap (7-445:32-427)

                                       10         20        30     
pF1KB8                         MHGHSRNGQAHVPRRKR-RNRFVKKNGQCNVYFANL
                                     ::...:  :.. :.:::::.:.::: : :.
NP_000 GSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINV
              10        20        30        40        50        60 

          40        50        60        70        80        90     
pF1KB8 SNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPA
       ..:.:::.::::::::: :::.::.::  ::..:::::: .:: ::..::::.::     
NP_000 GEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASK----
              70        80        90       100       110           

         100       110       120       130       140       150     
pF1KB8 AGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVV
             :         : :. .::.: .:::::.::::::::::::::.:::.::. :: 
NP_000 -----EG---------KACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF
                     120       130       140       150       160   

         160       170       180       190       200       210     
pF1KB8 QSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIV
       ::::::.::.:.::..:::::.:::: .::.:::.:::..::::::::::::::::::.:
NP_000 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV
           170       180       190       200       210       220   

         220       230       240       250       260       270     
pF1KB8 EAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMG
       ::::::::.:  .:.::::.:::: :.:::.: :.::::::::: :::::::::::: ..
NP_000 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS
           230       240       250       260       270       280   

         280       290       300       310       320       330     
pF1KB8 KEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSR
       :..... :::::::::::::::::::: ::::::.:::::::.:::.:::: .:::::::
NP_000 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR
           290       300       310       320       330       340   

         340       350       360       370       380       390     
pF1KB8 FHKTYEVAGTPCCSARELQESKITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAA
       ::::::: .:: ::::.: :.:  .  :     ..::::::.:: :.::.. :.      
NP_000 FHKTYEVPNTPLCSARDLAEKKYILSNA-----NSFCYENEVALTSKEEDDSEN------
           350       360       370            380       390        

         400       410       420       430       440     
pF1KB8 AVAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI
             :.  ... ..           .::.  :::.::.    :::: :
NP_000 ------GVPESTSTDTP--------PDIDLHN-QASVPLEPRPLRRESEI
                  400               410        420       

>>NP_037480 (OMIM: 603953) ATP-sensitive inward rectifie  (436 aa)
 initn: 1283 init1: 1209 opt: 1304  Z-score: 1433.8  bits: 274.5 E(85289): 4e-73
Smith-Waterman score: 1599; 59.1% identity (79.7% similar) in 403 aa overlap (3-397:30-414)

                                          10            20         
pF1KB8                            MHGHSRNGQAHVPRR----KRRNRFVKKNGQCN
                                    :  ::: : .: .    .::.:::::.:.::
NP_037 MGLARALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRRRGRFVKKDGHCN
               10        20        30        40        50        60

      30        40        50        60        70        80         
pF1KB8 VYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEA
       : :.::.... ::..:.::::::.:::.: ..:: .::.:::.::: :: :: .::::  
NP_037 VRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--
               70        80        90       100       110          

      90       100       110       120       130       140         
pF1KB8 SPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLA
                       :::  : ::. :: .::.::::..::::.:::: : :::::: :
NP_037 ----------------AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAA
                      120       130       140       150       160  

     150       160       170       180       190       200         
pF1KB8 VIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNL
       : :::.: :.:::.:.:..:..:::::.:::: .::.::..::...:: .::::::::::
NP_037 VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNL
            170       180       190       200       210       220  

     210       220       230       240       250       260         
pF1KB8 RKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDS
       :.::.:::::::::..: .: ::::.:::..:..::.: : ::::::::: ::::::  :
NP_037 RRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSAS
            230       240       250       260       270       280  

     270       280       290       300       310       320         
pF1KB8 PLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHY
       ::: .:. ::   :::.:::::::::::::::: ::::: .:.:::::::::.:.. :.:
NP_037 PLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQY
            290       300       310       320       330       340  

     330       340       350           360       370       380     
pF1KB8 KVDYSRFHKTYEVAGTPCCSARELQE----SKITVLPAPPPPPSAFCYENELALMSQEEE
       .::: .::.:::: ::: :::.::.:    .. ..  . :   .::::::::::   .::
NP_037 EVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEE
            350       360       370       380       390       400  

         390       400       410       420       430       440     
pF1KB8 EMEEEAAAAAAVAAGLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI
       . ..:.  . .:                                                
NP_037 DEDDETEEGNGVETEDGAASPRVLTPTLALTLPP                          
            410       420       430                                

>>XP_011541112 (OMIM: 600734,613485,613677) PREDICTED: G  (419 aa)
 initn: 1248 init1: 1027 opt: 1087  Z-score: 1195.5  bits: 230.3 E(85289): 7.5e-60
Smith-Waterman score: 1305; 49.1% identity (76.0% similar) in 405 aa overlap (15-414:47-419)

                               10        20        30        40    
pF1KB8                 MHGHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMA
                                     .: :.:...:.:.:::. .:.. .. ::..
XP_011 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQ-ETYRYLS
         20        30        40        50        60         70     

           50        60        70        80        90       100    
pF1KB8 DIFTTCVDTRWRYMLMIFSAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGG
       :.::: :: .::. :..:. .. :.:::::...: ::...:::.               :
XP_011 DLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHV-------------G
          80        90       100       110       120               

          110       120       130       140       150       160    
pF1KB8 GAAPVAPKPCIMHVNGFLGAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVID
           .   ::. ...::..:::::.::.:::::::: .::.:: ..: ..::.:.: ...
XP_011 DQEWI---PCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVN
               130       140       150       160       170         

          170       180       190       200       210       220    
pF1KB8 SFMIGTIMAKMARPKKRAQTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLI
       .::.: ...:...:::::.::.::..::::.:: :::::.:::.::.:::::: .::.::
XP_011 AFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLI
     180       190       200       210       220       230         

          230       240       250       260       270       280    
pF1KB8 KPYMTQEGEYLPLDQRDLNVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDF
       :  .:.:::..::.: :.:::.: : ::.:::::.:: :::.. ::.. :.. .:..:.:
XP_011 KSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEF
     240       250       260       270       280       290         

          290       300       310       320       330       340    
pF1KB8 EIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAG
       :.:::::::::::.:: ::::::. .:.:::::: ::.  ::. :.:::. :: :::. .
XP_011 EVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYET-N
     300       310       320       330       340       350         

          350            360       370       380       390         
pF1KB8 TPCCSARELQESK-----ITVLPAPPPPPSAFCYENELALMSQEEEEMEEEAAAAAAVAA
       :: : :.:: : :     .  ::.::   .  : :   : .. : :. ::.         
XP_011 TPSCCAKELAEMKREGRLLQYLPSPPLLGG--CAE---AGLDAEAEQNEEDEPK------
      360       370       380         390          400             

     400       410       420       430       440     
pF1KB8 GLGLEAGSKEEAGIIRMLEFGSHLDLERMQASLPLDNISYRRESAI
       :::   ::.:  : .                               
XP_011 GLG---GSREARGSV                               
       410                                           




445 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:58:45 2016 done: Fri Nov  4 12:58:47 2016
 Total Scan time:  9.720 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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