Result of FASTA (omim) for pF1KB8397
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8397, 462 aa
  1>>>pF1KB8397 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.6051+/-0.00064; mu= -3.5607+/- 0.037
 mean_var=675.2041+/-159.916, 0's: 0 Z-trim(114.0): 1929  B-trim: 0 in 0/55
 Lambda= 0.049358
 statistics sampled from 21170 (23636) to 21170 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.277), width:  16
 Scan time:  7.910

The best scores are:                                      opt bits E(85289)
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 3131 239.4 1.6e-62
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 3131 239.4 1.6e-62
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 3049 233.6 9.1e-61
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 3049 233.6 9.1e-61
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 3049 233.6 9.1e-61
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 2855 219.7 1.3e-56
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 2621 203.0 1.3e-51
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 2574 199.8 1.4e-50
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 2474 192.6 1.9e-48
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_016876567 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876566 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876565 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876564 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2145 169.1   2e-41
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2145 169.1   2e-41
XP_011524924 (OMIM: 125853,164731,240900) PREDICTE ( 400) 2111 166.7 1.1e-40
XP_011542315 (OMIM: 611223,615937) PREDICTED: RAC- ( 295) 1820 145.7 1.6e-34
XP_006711789 (OMIM: 611223,615937) PREDICTED: RAC- ( 247) 1561 127.1 5.2e-29
XP_011542316 (OMIM: 611223,615937) PREDICTED: RAC- ( 249) 1237 104.1 4.6e-22
NP_005618 (OMIM: 602958) serine/threonine-protein  ( 431) 1161 99.1 2.6e-20
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 1161 99.1 2.6e-20
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 1161 99.1 2.6e-20
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 1161 99.2 2.8e-20
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 1161 99.2 2.8e-20
NP_057360 (OMIM: 607589) serine/threonine-protein  ( 427) 1140 97.6 7.2e-20
NP_733794 (OMIM: 607589) serine/threonine-protein  ( 367) 1134 97.0   9e-20
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 1134 97.0   9e-20
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 1117 95.9 2.3e-19
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 1117 96.0 2.3e-19
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 1117 96.0 2.4e-19
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_011531280 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_016859977 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_016859976 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_011531277 (OMIM: 176975) PREDICTED: protein kin ( 641) 1117 96.2 2.7e-19
XP_016859975 (OMIM: 176975) PREDICTED: protein kin ( 641) 1117 96.2 2.7e-19


>>NP_859029 (OMIM: 611223,615937) RAC-gamma serine/threo  (465 aa)
 initn: 3131 init1: 3131 opt: 3131  Z-score: 1243.6  bits: 239.4 E(85289): 1.6e-62
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450       460     
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN   
       ::::::::::::::::::::::::::::::::::::::::::   
NP_859 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGNWKK
              430       440       450       460     

>>NP_001193658 (OMIM: 611223,615937) RAC-gamma serine/th  (465 aa)
 initn: 3131 init1: 3131 opt: 3131  Z-score: 1243.6  bits: 239.4 E(85289): 1.6e-62
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450       460     
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN   
       ::::::::::::::::::::::::::::::::::::::::::   
NP_001 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGNWKK
              430       440       450       460     

>>XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC-gamm  (479 aa)
 initn: 3043 init1: 3043 opt: 3049  Z-score: 1211.9  bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450         460                 
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN               
       ::::::::::::::::::::::::::::::: ...  ::                    
XP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
              430       440       450       460       470         

>>NP_005456 (OMIM: 611223,615937) RAC-gamma serine/threo  (479 aa)
 initn: 3043 init1: 3043 opt: 3049  Z-score: 1211.9  bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450         460                 
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN               
       ::::::::::::::::::::::::::::::: ...  ::                    
NP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
              430       440       450       460       470         

>>XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC-gamm  (479 aa)
 initn: 3043 init1: 3043 opt: 3049  Z-score: 1211.9  bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450         460                 
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN               
       ::::::::::::::::::::::::::::::: ...  ::                    
XP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
              430       440       450       460       470         

>>XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC-gamm  (435 aa)
 initn: 2854 init1: 2854 opt: 2855  Z-score: 1137.6  bits: 219.7 E(85289): 1.3e-56
Smith-Waterman score: 2855; 97.0% identity (97.7% similar) in 439 aa overlap (1-439:1-435)

               10        20        30        40        50        60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
              370       380       390       400       410       420

              430       440       450       460  
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
        :. .: :      ::. :                       
XP_011 LFRERVISLP----FDNAF                       
              430                                

>>XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC-gamm  (418 aa)
 initn: 2615 init1: 2615 opt: 2621  Z-score: 1047.7  bits: 203.0 E(85289): 1.3e-51
Smith-Waterman score: 2621; 98.5% identity (99.2% similar) in 398 aa overlap (62-457:1-398)

              40        50        60        70        80        90 
pF1KB8 DGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDT
                                     ::::::::::::::::::::::::::::::
XP_016                               MKTERPKPNTFIIRCLQWTTVIERTFHVDT
                                             10        20        30

             100       110       120       130       140       150 
pF1KB8 PEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYL
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KB8 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSL
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KB8 KYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRD
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KB8 LKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWG
              220       230       240       250       260       270

             340       350       360       370       380       390 
pF1KB8 LGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGG
              280       290       300       310       320       330

             400       410       420       430       440       450 
pF1KB8 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK
              340       350       360       370       380       390

               460                 
pF1KB8 CQQS--DCGMLGN               
        ...  ::                    
XP_016 YDEDGMDCMDNERRPHFPQFSYSASGRE
              400       410        

>>XP_005267458 (OMIM: 114480,114500,164730,167000,176920  (480 aa)
 initn: 2126 init1: 1127 opt: 2574  Z-score: 1029.1  bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)

               10        20        30        40         50         
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
       ::::.::::::..:::::::.:::::::::.::.::::::.:::::    ::::::::.:
XP_005 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
       ::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:. 
XP_005 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
               70        80        90       100       110       120

     120       130       140        150       160       170        
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
          :  :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
XP_005 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
       ::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
XP_005 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
              190       200       210       220       230       240

      240       250       260        270       280       290       
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
       :::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
XP_005 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
        :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
       ::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
XP_005 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
              370       380       390       400       410       420

       420       430       440       450       460                 
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN               
       : ::::::::::::::::::::::: ::::::.. .. .:                    
XP_005 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
              430       440       450       460       470       480

>>NP_005154 (OMIM: 114480,114500,164730,167000,176920,18  (480 aa)
 initn: 2126 init1: 1127 opt: 2574  Z-score: 1029.1  bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)

               10        20        30        40         50         
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
       ::::.::::::..:::::::.:::::::::.::.::::::.:::::    ::::::::.:
NP_005 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
       ::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:. 
NP_005 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
               70        80        90       100       110       120

     120       130       140        150       160       170        
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
          :  :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
NP_005 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
       ::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
NP_005 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
              190       200       210       220       230       240

      240       250       260        270       280       290       
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
       :::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
NP_005 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
        :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
       ::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
NP_005 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
              370       380       390       400       410       420

       420       430       440       450       460                 
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN               
       : ::::::::::::::::::::::: ::::::.. .. .:                    
NP_005 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
              430       440       450       460       470       480

>>NP_001014431 (OMIM: 114480,114500,164730,167000,176920  (480 aa)
 initn: 2126 init1: 1127 opt: 2574  Z-score: 1029.1  bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)

               10        20        30        40         50         
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
       ::::.::::::..:::::::.:::::::::.::.::::::.:::::    ::::::::.:
NP_001 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
       ::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:. 
NP_001 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
               70        80        90       100       110       120

     120       130       140        150       160       170        
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
          :  :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
NP_001 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
       ::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
NP_001 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
              190       200       210       220       230       240

      240       250       260        270       280       290       
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
       :::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
NP_001 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
        :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
       ::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
NP_001 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
              370       380       390       400       410       420

       420       430       440       450       460                 
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN               
       : ::::::::::::::::::::::: ::::::.. .. .:                    
NP_001 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
              430       440       450       460       470       480




462 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:33:51 2016 done: Fri Nov  4 12:33:52 2016
 Total Scan time:  7.910 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com