Result of FASTA (omim) for pF1KB7638
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7638, 381 aa
  1>>>pF1KB7638 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8077+/-0.000294; mu= 6.7785+/- 0.018
 mean_var=197.3161+/-39.108, 0's: 0 Z-trim(123.7): 9  B-trim: 644 in 1/58
 Lambda= 0.091305
 statistics sampled from 43939 (43958) to 43939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.515), width:  16
 Scan time: 10.070

The best scores are:                                      opt bits E(85289)
NP_004998 (OMIM: 180300,601022) NF-kappa-B inhibit ( 381) 2656 361.8 1.5e-99
NP_001138434 (OMIM: 180300,601022) NF-kappa-B inhi ( 358) 2501 341.3   2e-93
NP_001138435 (OMIM: 180300,601022) NF-kappa-B inhi ( 343) 1373 192.7 1.1e-48
NP_001138433 (OMIM: 180300,601022) NF-kappa-B inhi ( 366) 1373 192.8 1.1e-48


>>NP_004998 (OMIM: 180300,601022) NF-kappa-B inhibitor-l  (381 aa)
 initn: 2656 init1: 2656 opt: 2656  Z-score: 1908.1  bits: 361.8 E(85289): 1.5e-99
Smith-Waterman score: 2656; 99.7% identity (99.7% similar) in 381 aa overlap (1-381:1-381)

               10        20        30        40        50        60
pF1KB7 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSCRPPRAEGSSQSWRQQE
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_004 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
              310       320       330       340       350       360

              370       380 
pF1KB7 RVMGAVTALSQALNRHAEALK
       :::::::::::::::::::::
NP_004 RVMGAVTALSQALNRHAEALK
              370       380 

>>NP_001138434 (OMIM: 180300,601022) NF-kappa-B inhibito  (358 aa)
 initn: 2501 init1: 2501 opt: 2501  Z-score: 1798.1  bits: 341.3 E(85289): 2e-93
Smith-Waterman score: 2501; 99.7% identity (99.7% similar) in 358 aa overlap (24-381:1-358)

               10        20        30        40        50        60
pF1KB7 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
                              :::::::::::::::::::::::::::::::::::::
NP_001                        MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
                                      10        20        30       

               70        80        90       100       110       120
pF1KB7 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
        40        50        60        70        80        90       

              130       140       150       160       170       180
pF1KB7 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
       100       110       120       130       140       150       

              190       200       210       220       230       240
pF1KB7 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSCRPPRAEGSSQSWRQQE
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
       160       170       180       190       200       210       

              250       260       270       280       290       300
pF1KB7 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
       220       230       240       250       260       270       

              310       320       330       340       350       360
pF1KB7 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
       280       290       300       310       320       330       

              370       380 
pF1KB7 RVMGAVTALSQALNRHAEALK
       :::::::::::::::::::::
NP_001 RVMGAVTALSQALNRHAEALK
       340       350        

>>NP_001138435 (OMIM: 180300,601022) NF-kappa-B inhibito  (343 aa)
 initn: 1361 init1: 1361 opt: 1373  Z-score: 995.3  bits: 192.7 E(85289): 1.1e-48
Smith-Waterman score: 2353; 95.5% identity (95.5% similar) in 358 aa overlap (24-381:1-343)

               10        20        30        40        50        60
pF1KB7 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
                              :::::::::::::::::::::::::::::::::::::
NP_001                        MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
                                      10        20        30       

               70        80        90       100       110       120
pF1KB7 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
        40        50        60        70        80        90       

              130       140       150       160       170       180
pF1KB7 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_001 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG---------
       100       110       120       130       140                 

              190       200       210       220       230       240
pF1KB7 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSCRPPRAEGSSQSWRQQE
             ::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 ------DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
            150       160       170       180       190       200  

              250       260       270       280       290       300
pF1KB7 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
            210       220       230       240       250       260  

              310       320       330       340       350       360
pF1KB7 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
            270       280       290       300       310       320  

              370       380 
pF1KB7 RVMGAVTALSQALNRHAEALK
       :::::::::::::::::::::
NP_001 RVMGAVTALSQALNRHAEALK
            330       340   

>>NP_001138433 (OMIM: 180300,601022) NF-kappa-B inhibito  (366 aa)
 initn: 1361 init1: 1361 opt: 1373  Z-score: 995.0  bits: 192.8 E(85289): 1.1e-48
Smith-Waterman score: 2508; 95.8% identity (95.8% similar) in 381 aa overlap (1-381:1-366)

               10        20        30        40        50        60
pF1KB7 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
NP_001 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG---------
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KB7 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSCRPPRAEGSSQSWRQQE
             ::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 ------DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
                   180       190       200       210       220     

              250       260       270       280       290       300
pF1KB7 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KB7 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
         290       300       310       320       330       340     

              370       380 
pF1KB7 RVMGAVTALSQALNRHAEALK
       :::::::::::::::::::::
NP_001 RVMGAVTALSQALNRHAEALK
         350       360      




381 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:30:32 2016 done: Fri Nov  4 12:30:34 2016
 Total Scan time: 10.070 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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