Result of FASTA (omim) for pF1KB8369
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8369, 198 aa
  1>>>pF1KB8369 198 - 198 aa - 198 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9283+/-0.000265; mu= 8.2077+/- 0.017
 mean_var=133.9706+/-26.723, 0's: 0 Z-trim(123.2): 11  B-trim: 0 in 0/56
 Lambda= 0.110808
 statistics sampled from 42670 (42682) to 42670 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.5), width:  16
 Scan time:  6.090

The best scores are:                                      opt bits E(85289)
NP_004055 (OMIM: 600778,610755) cyclin-dependent k ( 198) 1367 228.5 5.7e-60
NP_000067 (OMIM: 130650,600856,614732) cyclin-depe ( 316)  258 51.3 1.9e-06
XP_016872577 (OMIM: 130650,600856,614732) PREDICTE ( 316)  258 51.3 1.9e-06
NP_001116102 (OMIM: 130650,600856,614732) cyclin-d ( 305)  251 50.2   4e-06
NP_001116103 (OMIM: 130650,600856,614732) cyclin-d ( 305)  251 50.2   4e-06
XP_005252789 (OMIM: 130650,600856,614732) PREDICTE ( 175)  247 49.4 4.1e-06
NP_001278478 (OMIM: 116899) cyclin-dependent kinas ( 198)  239 48.1 1.1e-05
NP_001207707 (OMIM: 116899) cyclin-dependent kinas ( 164)  236 47.6 1.3e-05
NP_001207706 (OMIM: 116899) cyclin-dependent kinas ( 164)  236 47.6 1.3e-05
NP_000380 (OMIM: 116899) cyclin-dependent kinase i ( 164)  236 47.6 1.3e-05
NP_510867 (OMIM: 116899) cyclin-dependent kinase i ( 164)  236 47.6 1.3e-05


>>NP_004055 (OMIM: 600778,610755) cyclin-dependent kinas  (198 aa)
 initn: 1367 init1: 1367 opt: 1367  Z-score: 1197.7  bits: 228.5 E(85289): 5.7e-60
Smith-Waterman score: 1367; 99.5% identity (99.5% similar) in 198 aa overlap (1-198:1-198)

               10        20        30        40        50        60
pF1KB8 MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPAAPLIG
       :::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_004 NFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 APANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 APANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPN
              130       140       150       160       170       180

              190        
pF1KB8 AGSVEQTPKKPGLRRRQT
       ::::::::::::::::::
NP_004 AGSVEQTPKKPGLRRRQT
              190        

>>NP_000067 (OMIM: 130650,600856,614732) cyclin-dependen  (316 aa)
 initn: 298 init1: 198 opt: 258  Z-score: 236.8  bits: 51.3 E(85289): 1.9e-06
Smith-Waterman score: 277; 37.2% identity (58.6% similar) in 145 aa overlap (1-123:1-143)

               10        20           30        40        50       
pF1KB8 MSNVRVSNGSPSLERMDARQAEHP---KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQ
       ::.. . . : ..::. :: .  :   . ::::.::::::::::.:.:. .  ...  .:
NP_000 MSDASLRSTS-TMERLVAR-GTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQ
               10          20        30        40        50        

        60        70          80        90                  100    
pF1KB8 RKWNFDFQNHKPLEG--KYEWQEVEKGSLPEFYYRP-----------PRPPKGACKV---
        .:..:::.  ::.:  . .: ::.. :.: :: .            :::   :  :   
NP_000 NRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPP
       60        70        80        90       100       110        

               110        120       130       140       150        
pF1KB8 --PAQESQDGSGSRPAA-PLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATD
         :: :: ::    :   : . .::                                   
NP_000 LEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVL
      120       130       140       150       160       170        

>>XP_016872577 (OMIM: 130650,600856,614732) PREDICTED: c  (316 aa)
 initn: 298 init1: 198 opt: 258  Z-score: 236.8  bits: 51.3 E(85289): 1.9e-06
Smith-Waterman score: 277; 37.2% identity (58.6% similar) in 145 aa overlap (1-123:1-143)

               10        20           30        40        50       
pF1KB8 MSNVRVSNGSPSLERMDARQAEHP---KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQ
       ::.. . . : ..::. :: .  :   . ::::.::::::::::.:.:. .  ...  .:
XP_016 MSDASLRSTS-TMERLVAR-GTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQ
               10          20        30        40        50        

        60        70          80        90                  100    
pF1KB8 RKWNFDFQNHKPLEG--KYEWQEVEKGSLPEFYYRP-----------PRPPKGACKV---
        .:..:::.  ::.:  . .: ::.. :.: :: .            :::   :  :   
XP_016 NRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPP
       60        70        80        90       100       110        

               110        120       130       140       150        
pF1KB8 --PAQESQDGSGSRPAA-PLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATD
         :: :: ::    :   : . .::                                   
XP_016 LEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVL
      120       130       140       150       160       170        

>>NP_001116102 (OMIM: 130650,600856,614732) cyclin-depen  (305 aa)
 initn: 298 init1: 198 opt: 251  Z-score: 230.9  bits: 50.2 E(85289): 4e-06
Smith-Waterman score: 270; 38.3% identity (57.9% similar) in 133 aa overlap (13-123:1-132)

               10        20           30        40        50       
pF1KB8 MSNVRVSNGSPSLERMDARQAEHP---KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQ
                   .::. :: .  :   . ::::.::::::::::.:.:. .  ...  .:
NP_001             MERLVAR-GTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQ
                            10        20        30        40       

        60        70          80        90                  100    
pF1KB8 RKWNFDFQNHKPLEG--KYEWQEVEKGSLPEFYYRP-----------PRPPKGACKV---
        .:..:::.  ::.:  . .: ::.. :.: :: .            :::   :  :   
NP_001 NRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPP
        50        60        70        80        90       100       

               110        120       130       140       150        
pF1KB8 --PAQESQDGSGSRPAA-PLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATD
         :: :: ::    :   : . .::                                   
NP_001 LEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVL
       110       120       130       140       150       160       

>>NP_001116103 (OMIM: 130650,600856,614732) cyclin-depen  (305 aa)
 initn: 298 init1: 198 opt: 251  Z-score: 230.9  bits: 50.2 E(85289): 4e-06
Smith-Waterman score: 270; 38.3% identity (57.9% similar) in 133 aa overlap (13-123:1-132)

               10        20           30        40        50       
pF1KB8 MSNVRVSNGSPSLERMDARQAEHP---KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQ
                   .::. :: .  :   . ::::.::::::::::.:.:. .  ...  .:
NP_001             MERLVAR-GTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQ
                            10        20        30        40       

        60        70          80        90                  100    
pF1KB8 RKWNFDFQNHKPLEG--KYEWQEVEKGSLPEFYYRP-----------PRPPKGACKV---
        .:..:::.  ::.:  . .: ::.. :.: :: .            :::   :  :   
NP_001 NRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPP
        50        60        70        80        90       100       

               110        120       130       140       150        
pF1KB8 --PAQESQDGSGSRPAA-PLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATD
         :: :: ::    :   : . .::                                   
NP_001 LEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVL
       110       120       130       140       150       160       

>>XP_005252789 (OMIM: 130650,600856,614732) PREDICTED: c  (175 aa)
 initn: 212 init1: 198 opt: 247  Z-score: 230.8  bits: 49.4 E(85289): 4.1e-06
Smith-Waterman score: 247; 44.4% identity (72.8% similar) in 81 aa overlap (13-88:1-80)

               10        20           30        40        50       
pF1KB8 MSNVRVSNGSPSLERMDARQAEHP---KPSACRNLFGPVDHEELTRDLEKHCRDMEEASQ
                   .::. :: .  :   . ::::.::::::::::.:.:. .  ...  .:
XP_005             MERLVAR-GTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQ
                            10        20        30        40       

        60        70          80        90       100       110     
pF1KB8 RKWNFDFQNHKPLEG--KYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPA
        .:..:::.  ::.:  . .: ::.. :.: ::                           
XP_005 NRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQISSPSARDQRLRSRRAMSPRRV
        50        60        70        80        90       100       

         120       130       140       150       160       170     
pF1KB8 APLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVS
                                                                   
XP_005 PLQAPPLAWARWSRPRARGCGEPKPKEPRGNLPGQRTLEGRWASAGTVHVAATGGGCRRA
       110       120       130       140       150       160       

>>NP_001278478 (OMIM: 116899) cyclin-dependent kinase in  (198 aa)
 initn: 226 init1: 202 opt: 239  Z-score: 223.1  bits: 48.1 E(85289): 1.1e-05
Smith-Waterman score: 239; 32.6% identity (58.1% similar) in 172 aa overlap (8-166:32-189)

                                      10        20         30      
pF1KB8                        MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPV
                                     .:. :    :.::  .:  : ::: :::::
NP_001 WGVFRRQTTHSSNPPLPGQQSCCNHRDFFCSGAMSEPAGDVRQ--NPCGSKACRRLFGPV
              10        20        30        40          50         

         40           50        60        70        80        90   
pF1KB8 DHEELTRD---LEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPR
       : :.:.::   :   :  ..:: .: ::::: .. :::: . :..:.  .::..:  :  
NP_001 DSEQLSRDCDALMAGC--IQEARER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTG
      60        70          80         90       100       110      

           100       110       120       130                140    
pF1KB8 PPKGACKVPAQESQDGSGSRPAAPLIGAPANSEDTHLVD--------PKT-DPSDSQTGL
       : .:       ... :.: ::..      ...:. : ::        :.. . .... : 
NP_001 PRRG-------RDELGGGRRPGTSPALLQGTAEEDH-VDLSLSCTLVPRSGEQAEGSPGG
                120       130       140        150       160       

          150       160       170       180       190        
pF1KB8 AEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
         .  : ..: ..  .  ..::                                
NP_001 PGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP                       
       170       180       190                               

>>NP_001207707 (OMIM: 116899) cyclin-dependent kinase in  (164 aa)
 initn: 226 init1: 202 opt: 236  Z-score: 221.7  bits: 47.6 E(85289): 1.3e-05
Smith-Waterman score: 236; 33.1% identity (58.9% similar) in 163 aa overlap (17-166:7-155)

               10        20         30        40           50      
pF1KB8 MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPVDHEELTRD---LEKHCRDMEEAS
                       :.::  .:  : ::: :::::: :.:.::   :   :  ..:: 
NP_001           MSEPAGDVRQ--NPCGSKACRRLFGPVDSEQLSRDCDALMAGC--IQEAR
                         10          20        30        40        

         60        70        80        90       100       110      
pF1KB8 QRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPAA
       .: ::::: .. :::: . :..:.  .::..:  :  : .:       ... :.: ::..
NP_001 ER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTGPRRG-------RDELGGGRRPGT
          50        60        70         80               90       

        120       130                140       150       160       
pF1KB8 PLIGAPANSEDTHLVD--------PKT-DPSDSQTGLAEQCAGIRKRPATDDSSTQNKRA
             ...:. : ::        :.. . .... :   .  : ..: ..  .  ..:: 
NP_001 SPALLQGTAEEDH-VDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRR
       100       110        120       130       140       150      

       170       180       190        
pF1KB8 NRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
                                      
NP_001 LIFSKRKP                       
        160                           

>>NP_001207706 (OMIM: 116899) cyclin-dependent kinase in  (164 aa)
 initn: 226 init1: 202 opt: 236  Z-score: 221.7  bits: 47.6 E(85289): 1.3e-05
Smith-Waterman score: 236; 33.1% identity (58.9% similar) in 163 aa overlap (17-166:7-155)

               10        20         30        40           50      
pF1KB8 MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPVDHEELTRD---LEKHCRDMEEAS
                       :.::  .:  : ::: :::::: :.:.::   :   :  ..:: 
NP_001           MSEPAGDVRQ--NPCGSKACRRLFGPVDSEQLSRDCDALMAGC--IQEAR
                         10          20        30        40        

         60        70        80        90       100       110      
pF1KB8 QRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPAA
       .: ::::: .. :::: . :..:.  .::..:  :  : .:       ... :.: ::..
NP_001 ER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTGPRRG-------RDELGGGRRPGT
          50        60        70         80               90       

        120       130                140       150       160       
pF1KB8 PLIGAPANSEDTHLVD--------PKT-DPSDSQTGLAEQCAGIRKRPATDDSSTQNKRA
             ...:. : ::        :.. . .... :   .  : ..: ..  .  ..:: 
NP_001 SPALLQGTAEEDH-VDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRR
       100       110        120       130       140       150      

       170       180       190        
pF1KB8 NRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
                                      
NP_001 LIFSKRKP                       
        160                           

>>NP_000380 (OMIM: 116899) cyclin-dependent kinase inhib  (164 aa)
 initn: 226 init1: 202 opt: 236  Z-score: 221.7  bits: 47.6 E(85289): 1.3e-05
Smith-Waterman score: 236; 33.1% identity (58.9% similar) in 163 aa overlap (17-166:7-155)

               10        20         30        40           50      
pF1KB8 MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPVDHEELTRD---LEKHCRDMEEAS
                       :.::  .:  : ::: :::::: :.:.::   :   :  ..:: 
NP_000           MSEPAGDVRQ--NPCGSKACRRLFGPVDSEQLSRDCDALMAGC--IQEAR
                         10          20        30        40        

         60        70        80        90       100       110      
pF1KB8 QRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDGSGSRPAA
       .: ::::: .. :::: . :..:.  .::..:  :  : .:       ... :.: ::..
NP_000 ER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTGPRRG-------RDELGGGRRPGT
          50        60        70         80               90       

        120       130                140       150       160       
pF1KB8 PLIGAPANSEDTHLVD--------PKT-DPSDSQTGLAEQCAGIRKRPATDDSSTQNKRA
             ...:. : ::        :.. . .... :   .  : ..: ..  .  ..:: 
NP_000 SPALLQGTAEEDH-VDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRR
       100       110        120       130       140       150      

       170       180       190        
pF1KB8 NRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
                                      
NP_000 LIFSKRKP                       
        160                           




198 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 12:19:04 2016 done: Fri Nov  4 12:19:05 2016
 Total Scan time:  6.090 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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