Result of FASTA (omim) for pF1KB8333
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8333, 313 aa
  1>>>pF1KB8333 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0430+/-0.000402; mu= 17.3676+/- 0.025
 mean_var=69.5191+/-13.740, 0's: 0 Z-trim(112.9): 110  B-trim: 1234 in 1/49
 Lambda= 0.153823
 statistics sampled from 21856 (21971) to 21856 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.258), width:  16
 Scan time:  4.570

The best scores are:                                      opt bits E(85289)
NP_001129522 (OMIM: 610410) dehydrogenase/reductas ( 313) 2085 471.8 7.9e-133
NP_612461 (OMIM: 610410) dehydrogenase/reductase S ( 313) 2085 471.8 7.9e-133
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303)  229 59.9 7.6e-09
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261)  228 59.6 7.8e-09
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260)  223 58.5 1.7e-08
NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reduct ( 326)  216 57.0 5.9e-08
XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  216 57.0 5.9e-08
XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  216 57.0 5.9e-08
XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326)  216 57.0 5.9e-08
NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase ( 335)  216 57.0   6e-08
NP_057110 (OMIM: 607849,616108) retinol dehydrogen ( 318)  209 55.5 1.7e-07
NP_689656 (OMIM: 608830,612712) retinol dehydrogen ( 316)  204 54.4 3.7e-07
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278)  199 53.2 7.1e-07
NP_001193670 (OMIM: 600713,614662) corticosteroid  ( 292)  197 52.8   1e-06
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292)  197 52.8   1e-06
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292)  197 52.8   1e-06
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302)  197 52.8   1e-06
XP_005257715 (OMIM: 616159) PREDICTED: dehydrogena ( 229)  195 52.3 1.1e-06
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine  ( 332)  189 51.0 3.8e-06
XP_005259027 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 140)  184 49.7 4.2e-06
XP_005259026 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 212)  184 49.8 5.8e-06
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  185 50.1 6.2e-06
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280)  185 50.1 6.2e-06
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280)  185 50.1 6.2e-06
NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid de ( 270)  184 49.9   7e-06
NP_000851 (OMIM: 119900,259100,601688) 15-hydroxyp ( 266)  183 49.6 8.1e-06
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300)  182 49.5   1e-05
NP_000405 (OMIM: 233400,261515,601860) peroxisomal ( 736)  185 50.4 1.3e-05
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298)  180 49.0 1.4e-05
NP_653284 (OMIM: 616157) dehydrogenase/reductase S ( 377)  180 49.1 1.7e-05
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309)  178 48.6   2e-05
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318)  178 48.6   2e-05
NP_001243234 (OMIM: 119900,259100,601688) 15-hydro ( 143)  169 46.3 4.3e-05
XP_011530209 (OMIM: 119900,259100,601688) PREDICTE ( 176)  169 46.4 5.1e-05
NP_001139288 (OMIM: 119900,259100,601688) 15-hydro ( 178)  169 46.4 5.1e-05
NP_001317148 (OMIM: 109684) estradiol 17-beta-dehy ( 329)  169 46.6 8.2e-05
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232)  167 46.0 8.5e-05
XP_011523031 (OMIM: 109684) PREDICTED: estradiol 1 ( 384)  169 46.7 9.3e-05
NP_003115 (OMIM: 182125,612716) sepiapterin reduct ( 261)  166 45.9 0.00011
NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-C ( 292)  163 45.2 0.00019
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328)  163 45.3 0.00021
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300)  162 45.0 0.00022
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383)  163 45.3 0.00023
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312)  161 44.8 0.00027
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339)  161 44.8 0.00029
NP_001239579 (OMIM: 607849,616108) retinol dehydro ( 248)  159 44.3 0.00031
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404)  161 44.9 0.00033
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289)  159 44.3 0.00035
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310)  159 44.4 0.00036
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325)  159 44.4 0.00038


>>NP_001129522 (OMIM: 610410) dehydrogenase/reductase SD  (313 aa)
 initn: 2085 init1: 2085 opt: 2085  Z-score: 2505.6  bits: 471.8 E(85289): 7.9e-133
Smith-Waterman score: 2085; 99.7% identity (100.0% similar) in 313 aa overlap (1-313:1-313)

               10        20        30        40        50        60
pF1KB8 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR
              250       260       270       280       290       300

              310   
pF1KB8 VPRWIIALYTSKF
       ::.::::::::::
NP_001 VPKWIIALYTSKF
              310   

>>NP_612461 (OMIM: 610410) dehydrogenase/reductase SDR f  (313 aa)
 initn: 2085 init1: 2085 opt: 2085  Z-score: 2505.6  bits: 471.8 E(85289): 7.9e-133
Smith-Waterman score: 2085; 99.7% identity (100.0% similar) in 313 aa overlap (1-313:1-313)

               10        20        30        40        50        60
pF1KB8 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR
              250       260       270       280       290       300

              310   
pF1KB8 VPRWIIALYTSKF
       ::.::::::::::
NP_612 VPKWIIALYTSKF
              310   

>>NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl-CoA  (303 aa)
 initn: 125 init1: 125 opt: 229  Z-score: 279.8  bits: 59.9 E(85289): 7.6e-09
Smith-Waterman score: 229; 27.8% identity (59.9% similar) in 212 aa overlap (3-204:12-212)

                          10        20        30        40         
pF1KB8          MAAP--MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQ
                  ::  ..::: .:::.. :::..:. .: . :..: :..:.:. :. .:.
NP_060 MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD
               10        20        30        40        50        60

      50             60        70        80        90       100    
pF1KB8 EAQ-----SLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTR
       : :     .  .. .:. :.  .: :: .: ...  .  :... ::::.  : : .  ..
NP_060 ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKST-LDTFGKINFLVNNG--GGQFLSPAE
               70        80        90        100         110       

          110       120        130       140       150       160   
pF1KB8 NKAFWETPASMWDDINNVGLRG-HYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPY
       . .     .. :  . ...: :  :.:..  .  :   : : :: :  : .  . . :  
NP_060 HIS-----SKGWHAVLETNLTGTFYMCKAVYSSWMKEHG-GSIVNIIVPTKAGFPLAVHS
       120            130       140       150        160       170 

           170       180         190       200       210       220 
pF1KB8 GVGKAACDKLAADCAHELRRHGV--SCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKS
       :...:.  .:. . : :    :.  .::.  ::.. ..   :.                 
NP_060 GAARAGVYNLTKSLALEWACSGIRINCVA--PGVIYSQTAVENYGSWGQSFFEGSFQKIP
             180       190       200         210       220         

             230       240       250       260       270       280 
pF1KB8 AFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSV
                                                                   
NP_060 AKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSV
     230       240       250       260       270       280         

>>NP_055049 (OMIM: 601417) estradiol 17-beta-dehydrogena  (261 aa)
 initn: 181 init1:  91 opt: 228  Z-score: 279.5  bits: 59.6 E(85289): 7.8e-09
Smith-Waterman score: 228; 29.7% identity (57.5% similar) in 212 aa overlap (5-203:9-209)

                   10        20        30        40        50      
pF1KB8     MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEA-QSLG
               . . . .::::. ::::.....:   ::::       :  :..:::. . ::
NP_055 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAAC----DLDRAAAQETVRLLG
               10        20        30        40            50      

              60              70        80        90       100     
pF1KB8 G----QCVP------VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRN
       :    .  :         : :.   .: :.:::.   .   .:.:. :  :.     :..
NP_055 GPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCA--GI-----TQD
         60        70        80        90       100                

         110       120       130       140        150        160   
pF1KB8 KAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAG-QGLIVVISSP-GSLQYMFNVPY
       . . .   . :: .  :.:.: .. .  .:. .:  : .: :. :::  :..  . .. :
NP_055 EFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNY
     110       120       130       140       150       160         

           170       180       190       200       210       220   
pF1KB8 GVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAF
       ...::.   :.   :.:: :::. : :. ::.. : . ..                    
NP_055 AASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGD
     170       180       190       200       210       220         

           230       240       250       260       270       280   
pF1KB8 SSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLS
                                                                   
NP_055 PEDVADVVAFLASEDSGYITGTSVEVTGGLFM                            
     230       240       250       260                             

>>NP_077284 (OMIM: 616159) dehydrogenase/reductase SDR f  (260 aa)
 initn:  82 init1:  64 opt: 223  Z-score: 273.6  bits: 58.5 E(85289): 1.7e-08
Smith-Waterman score: 223; 29.2% identity (57.9% similar) in 209 aa overlap (8-204:12-210)

                   10        20        30        40        50      
pF1KB8     MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-
                  .. .::::: ::: ..:  : . :  :   .: . ... .: : .: : 
NP_077 MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGY
               10        20        30        40        50        60

           60        70        80        90       100       110    
pF1KB8 -GQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPAS
        :  .:  :: :.: .. :.:  . : :.. .:. .::  ::.     .:  ..    .:
NP_077 PGTLIPYRCDLSNEEDILSMFSAI-RSQHSGVDICINN--AGL-----ARPDTLLSGSTS
               70        80         90         100            110  

          120       130         140       150        160           
pF1KB8 MWDDINNVGLRGHYFCS--VYGARLMVPAGQGLIVVISSPGSLQYM-FNVP--YGVGKAA
        : :. ::.. .  .:.  .: .     . .: :. :.: .. . . ..:   :.. : :
NP_077 GWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYA
            120       130       140       150       160       170  

     170       180           190       200        210       220    
pF1KB8 CDKLAADCAHELRR---H-GVSCVSLWPGIVQTEL-LKEHMAKEEVLQDPVLKQFKSAFS
          :.    .:::.   :  ..:.:  ::.:.:.. .: :                    
NP_077 VTALTEGLRQELREAQTHIRATCIS--PGVVETQFAFKLHDKDPEKAAATYEQMKCLKPE
            180       190         200       210       220       230

          230       240       250       260       270       280    
pF1KB8 SAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSH
                                                                   
NP_077 DVAEAVIYVLSTPAHIQIGDIQMRPTEQVT                              
              240       250       260                              

>>NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reductase,  (326 aa)
 initn: 101 init1:  61 opt: 216  Z-score: 263.8  bits: 57.0 E(85289): 5.9e-08
Smith-Waterman score: 216; 24.0% identity (58.7% similar) in 196 aa overlap (7-199:50-237)

                                       10        20        30      
pF1KB8                         MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYI
                                     :.:  .::.. :.:.:..  : . ::   :
NP_001 TKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVI
      20        30        40        50        60        70         

         40        50        60         70        80        90     
pF1KB8 TGRHLDTLRVVAQEAQSLGGQCVPVV-CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYA
       ..:..:.:...:.. .:  :. : .. ::  . . :..   .. .   :. ....::: :
NP_001 ASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVA-GHPNIVINNA-A
      80        90       100       110       120        130        

         100       110       120       130       140         150   
pF1KB8 GVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQG--LIVVISSPG
       :     :  . .   .: . :  :... : :  : ..  .. .. : .:  .. . .  .
NP_001 G-----NFISPTERLSPNA-WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYA
            140       150        160       170       180       190 

           160       170       180       190       200       210   
pF1KB8 SLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQD
            : :: . .::. . .. . : :  ..:.    . :: ..:.              
NP_001 ETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK
             200       210       220       230       240       250 

           220       230       240       250       260       270   
pF1KB8 PVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQ
                                                                   
NP_001 EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKE
             260       270       280       290       300       310 

>>XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 101 init1:  61 opt: 216  Z-score: 263.8  bits: 57.0 E(85289): 5.9e-08
Smith-Waterman score: 216; 24.0% identity (58.7% similar) in 196 aa overlap (7-199:50-237)

                                       10        20        30      
pF1KB8                         MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYI
                                     :.:  .::.. :.:.:..  : . ::   :
XP_016 TKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVI
      20        30        40        50        60        70         

         40        50        60         70        80        90     
pF1KB8 TGRHLDTLRVVAQEAQSLGGQCVPVV-CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYA
       ..:..:.:...:.. .:  :. : .. ::  . . :..   .. .   :. ....::: :
XP_016 ASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVA-GHPNIVINNA-A
      80        90       100       110       120        130        

         100       110       120       130       140         150   
pF1KB8 GVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQG--LIVVISSPG
       :     :  . .   .: . :  :... : :  : ..  .. .. : .:  .. . .  .
XP_016 G-----NFISPTERLSPNA-WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYA
            140       150        160       170       180       190 

           160       170       180       190       200       210   
pF1KB8 SLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQD
            : :: . .::. . .. . : :  ..:.    . :: ..:.              
XP_016 ETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK
             200       210       220       230       240       250 

           220       230       240       250       260       270   
pF1KB8 PVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQ
                                                                   
XP_016 EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKE
             260       270       280       290       300       310 

>>XP_011515182 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 101 init1:  61 opt: 216  Z-score: 263.8  bits: 57.0 E(85289): 5.9e-08
Smith-Waterman score: 216; 24.0% identity (58.7% similar) in 196 aa overlap (7-199:50-237)

                                       10        20        30      
pF1KB8                         MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYI
                                     :.:  .::.. :.:.:..  : . ::   :
XP_011 TKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVI
      20        30        40        50        60        70         

         40        50        60         70        80        90     
pF1KB8 TGRHLDTLRVVAQEAQSLGGQCVPVV-CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYA
       ..:..:.:...:.. .:  :. : .. ::  . . :..   .. .   :. ....::: :
XP_011 ASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVA-GHPNIVINNA-A
      80        90       100       110       120        130        

         100       110       120       130       140         150   
pF1KB8 GVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQG--LIVVISSPG
       :     :  . .   .: . :  :... : :  : ..  .. .. : .:  .. . .  .
XP_011 G-----NFISPTERLSPNA-WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYA
            140       150        160       170       180       190 

           160       170       180       190       200       210   
pF1KB8 SLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQD
            : :: . .::. . .. . : :  ..:.    . :: ..:.              
XP_011 ETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK
             200       210       220       230       240       250 

           220       230       240       250       260       270   
pF1KB8 PVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQ
                                                                   
XP_011 EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKE
             260       270       280       290       300       310 

>>XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl-CoA  (326 aa)
 initn: 101 init1:  61 opt: 216  Z-score: 263.8  bits: 57.0 E(85289): 5.9e-08
Smith-Waterman score: 216; 24.0% identity (58.7% similar) in 196 aa overlap (7-199:50-237)

                                       10        20        30      
pF1KB8                         MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYI
                                     :.:  .::.. :.:.:..  : . ::   :
XP_016 TKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVI
      20        30        40        50        60        70         

         40        50        60         70        80        90     
pF1KB8 TGRHLDTLRVVAQEAQSLGGQCVPVV-CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYA
       ..:..:.:...:.. .:  :. : .. ::  . . :..   .. .   :. ....::: :
XP_016 ASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVA-GHPNIVINNA-A
      80        90       100       110       120        130        

         100       110       120       130       140         150   
pF1KB8 GVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQG--LIVVISSPG
       :     :  . .   .: . :  :... : :  : ..  .. .. : .:  .. . .  .
XP_016 G-----NFISPTERLSPNA-WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYA
            140       150        160       170       180       190 

           160       170       180       190       200       210   
pF1KB8 SLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQD
            : :: . .::. . .. . : :  ..:.    . :: ..:.              
XP_016 ETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK
             200       210       220       230       240       250 

           220       230       240       250       260       270   
pF1KB8 PVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQ
                                                                   
XP_016 EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKE
             260       270       280       290       300       310 

>>NP_001350 (OMIM: 222745) 2,4-dienoyl-CoA reductase, mi  (335 aa)
 initn: 101 init1:  61 opt: 216  Z-score: 263.6  bits: 57.0 E(85289): 6e-08
Smith-Waterman score: 216; 24.0% identity (58.7% similar) in 196 aa overlap (7-199:59-246)

                                       10        20        30      
pF1KB8                         MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYI
                                     :.:  .::.. :.:.:..  : . ::   :
NP_001 TKILYQNTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVI
       30        40        50        60        70        80        

         40        50        60         70        80        90     
pF1KB8 TGRHLDTLRVVAQEAQSLGGQCVPVV-CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYA
       ..:..:.:...:.. .:  :. : .. ::  . . :..   .. .   :. ....::: :
NP_001 ASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVA-GHPNIVINNA-A
       90       100       110       120       130        140       

         100       110       120       130       140         150   
pF1KB8 GVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQG--LIVVISSPG
       :     :  . .   .: . :  :... : :  : ..  .. .. : .:  .. . .  .
NP_001 G-----NFISPTERLSPNA-WKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYA
             150       160        170       180       190       200

           160       170       180       190       200       210   
pF1KB8 SLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQD
            : :: . .::. . .. . : :  ..:.    . :: ..:.              
NP_001 ETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEK
              210       220       230       240       250       260

           220       230       240       250       260       270   
pF1KB8 PVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQ
                                                                   
NP_001 EMIGRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKE
              270       280       290       300       310       320




313 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:51:03 2016 done: Fri Nov  4 11:51:04 2016
 Total Scan time:  4.570 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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