Result of FASTA (omim) for pF1KB8221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8221, 248 aa
  1>>>pF1KB8221 248 - 248 aa - 248 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.4143+/-0.000288; mu= 7.0546+/- 0.018
 mean_var=155.1264+/-31.527, 0's: 0 Z-trim(122.2): 16  B-trim: 0 in 0/55
 Lambda= 0.102975
 statistics sampled from 39927 (39943) to 39927 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.468), width:  16
 Scan time:  6.530

The best scores are:                                      opt bits E(85289)
NP_009027 (OMIM: 118960) clathrin light chain A is ( 248) 1675 259.6 3.9e-69
NP_001070145 (OMIM: 118960) clathrin light chain A ( 236) 1221 192.1 7.5e-49
XP_016869746 (OMIM: 118960) PREDICTED: clathrin li ( 170) 1130 178.5 6.8e-45
NP_001824 (OMIM: 118960) clathrin light chain A is ( 218) 1127 178.1 1.1e-44
NP_001171690 (OMIM: 118960) clathrin light chain A ( 168) 1094 173.1 2.8e-43
NP_001171689 (OMIM: 118960) clathrin light chain A ( 230) 1094 173.2 3.5e-43
NP_001298133 (OMIM: 118960) clathrin light chain A ( 196)  833 134.4 1.5e-31
NP_009028 (OMIM: 118970) clathrin light chain B is ( 229)  648 107.0 3.1e-23
NP_001298132 (OMIM: 118960) clathrin light chain A ( 140)  582 97.0 1.9e-20
NP_001825 (OMIM: 118970) clathrin light chain B is ( 211)  581 97.0 2.9e-20
XP_016869747 (OMIM: 118960) PREDICTED: clathrin li ( 152)  549 92.1   6e-19
NP_001171691 (OMIM: 118960) clathrin light chain A ( 166)  532 89.6 3.7e-18
NP_001298134 (OMIM: 118960) clathrin light chain A ( 178)  524 88.4 8.9e-18
XP_016864515 (OMIM: 118970) PREDICTED: clathrin li ( 144)  409 71.3 1.1e-12
NP_001298135 (OMIM: 118960) clathrin light chain A ( 101)  369 65.2 4.9e-11
XP_016864516 (OMIM: 118970) PREDICTED: clathrin li ( 134)  200 40.2  0.0022


>>NP_009027 (OMIM: 118960) clathrin light chain A isofor  (248 aa)
 initn: 1675 init1: 1675 opt: 1675  Z-score: 1362.3  bits: 259.6 E(85289): 3.9e-69
Smith-Waterman score: 1675; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
              190       200       210       220       230       240

               
pF1KB8 LKQAPLVH
       ::::::::
NP_009 LKQAPLVH
               

>>NP_001070145 (OMIM: 118960) clathrin light chain A iso  (236 aa)
 initn: 1573 init1: 1221 opt: 1221  Z-score: 998.1  bits: 192.1 E(85289): 7.5e-49
Smith-Waterman score: 1553; 95.2% identity (95.2% similar) in 248 aa overlap (1-248:1-236)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
                          190       200       210       220        

               
pF1KB8 LKQAPLVH
       ::::::::
NP_001 LKQAPLVH
      230      

>>XP_016869746 (OMIM: 118960) PREDICTED: clathrin light   (170 aa)
 initn: 1130 init1: 1130 opt: 1130  Z-score: 926.9  bits: 178.5 E(85289): 6.8e-45
Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 170 aa overlap (79-248:1-170)

       50        60        70        80        90       100        
pF1KB8 DEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPE
                                     ::::::::::::::::::::::::::::::
XP_016                               MNGEYYQESNGPTDSYAAISQVDRLQSEPE
                                             10        20        30

      110       120       130       140       150       160        
pF1KB8 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
               40        50        60        70        80        90

      170       180       190       200       210       220        
pF1KB8 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
              100       110       120       130       140       150

      230       240        
pF1KB8 KDVSRMRSVLISLKQAPLVH
       ::::::::::::::::::::
XP_016 KDVSRMRSVLISLKQAPLVH
              160       170

>>NP_001824 (OMIM: 118960) clathrin light chain A isofor  (218 aa)
 initn: 1127 init1: 1127 opt: 1127  Z-score: 923.1  bits: 178.1 E(85289): 1.1e-44
Smith-Waterman score: 1397; 87.9% identity (87.9% similar) in 248 aa overlap (1-248:1-218)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
       ::::::::::::::::::::::::::::::::::::::::::                  
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------------------
              130       140       150       160                    

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
                        170       180       190       200       210

               
pF1KB8 LKQAPLVH
       ::::::::
NP_001 LKQAPLVH
               

>>NP_001171690 (OMIM: 118960) clathrin light chain A iso  (168 aa)
 initn: 1094 init1: 1094 opt: 1094  Z-score: 898.1  bits: 173.1 E(85289): 2.8e-43
Smith-Waterman score: 1094; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
       :::::::::::::::::::::::::::::::::::::::::                   
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSRRSLCK            
              130       140       150       160                    

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS

>>NP_001171689 (OMIM: 118960) clathrin light chain A iso  (230 aa)
 initn: 1534 init1: 1094 opt: 1094  Z-score: 896.2  bits: 173.2 E(85289): 3.5e-43
Smith-Waterman score: 1501; 92.3% identity (92.3% similar) in 248 aa overlap (1-248:1-230)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
       :::::::::::::::::::::::::::::::::::::::::                   
NP_001 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNS------------------
              130       140       150       160                    

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
            170       180       190       200       210       220  

               
pF1KB8 LKQAPLVH
       ::::::::
NP_001 LKQAPLVH
            230

>>NP_001298133 (OMIM: 118960) clathrin light chain A iso  (196 aa)
 initn: 826 init1: 826 opt: 833  Z-score: 687.6  bits: 134.4 E(85289): 1.5e-31
Smith-Waterman score: 1218; 79.0% identity (79.0% similar) in 248 aa overlap (1-248:1-196)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMER
       ::::::::::::                                                
NP_001 GPQPHGEPPGGP------------------------------------------------
               70                                                  

              130       140       150       160       170       180
pF1KB8 LEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----DANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYV
                 80        90       100       110       120        

              190       200       210       220       230       240
pF1KB8 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
      130       140       150       160       170       180        

               
pF1KB8 LKQAPLVH
       ::::::::
NP_001 LKQAPLVH
      190      

>>NP_009028 (OMIM: 118970) clathrin light chain B isofor  (229 aa)
 initn: 677 init1: 490 opt: 648  Z-score: 538.2  bits: 107.0 E(85289): 3.1e-23
Smith-Waterman score: 893; 61.2% identity (79.3% similar) in 227 aa overlap (21-246:13-227)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
                           .:.  :.:::::::::::::::::::::::.:.   :.  
NP_009         MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
                       10        20        30        40        50  

               70         80        90       100       110         
pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
       .:   :   : : . .  ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_009 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
             60        70        80        90       100       110  

     120       130       140       150       160       170         
pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
       ::. ::: :.  : ::.::: :.::::  ::.::..:.: :::.::.:::.:: ::.:::
NP_009 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
            120       130       140       150       160       170  

     180       190       200       210       220       230         
pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI
       :            :.:::::..  : .::::::.::.::::::::::: :::::.::::.
NP_009 V------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM
                        180       190       200       210       220

     240        
pF1KB8 SLKQAPLVH
       ::::.::  
NP_009 SLKQTPLSR
                

>>NP_001298132 (OMIM: 118960) clathrin light chain A iso  (140 aa)
 initn: 582 init1: 582 opt: 582  Z-score: 488.1  bits: 97.0 E(85289): 1.9e-20
Smith-Waterman score: 852; 82.4% identity (82.4% similar) in 170 aa overlap (79-248:1-140)

       50        60        70        80        90       100        
pF1KB8 DEAFAILDGGAPGPQPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPE
                                     ::::::::::::::::::::::::::::::
NP_001                               MNGEYYQESNGPTDSYAAISQVDRLQSEPE
                                             10        20        30

      110       120       130       140       150       160        
pF1KB8 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_001 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR------
               40        50        60        70        80          

      170       180       190       200       210       220        
pF1KB8 YKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
                               ::::::::::::::::::::::::::::::::::::
NP_001 ------------------------AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA
                                   90       100       110       120

      230       240        
pF1KB8 KDVSRMRSVLISLKQAPLVH
       ::::::::::::::::::::
NP_001 KDVSRMRSVLISLKQAPLVH
              130       140

>>NP_001825 (OMIM: 118970) clathrin light chain B isofor  (211 aa)
 initn: 625 init1: 422 opt: 581  Z-score: 484.9  bits: 97.0 E(85289): 2.9e-20
Smith-Waterman score: 761; 55.5% identity (71.8% similar) in 227 aa overlap (21-246:13-209)

               10        20        30        40        50        60
pF1KB8 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
                           .:.  :.:::::::::::::::::::::::.:.   :.  
NP_001         MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
                       10        20        30        40        50  

               70         80        90       100       110         
pF1KB8 GPQPHGEPPG-GPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
       .:   :   : : . .  ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
             60        70        80        90       100       110  

     120       130       140       150       160       170         
pF1KB8 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
       ::. ::: :.  : ::.::: :.::::  ::.::..:.: :::                 
NP_001 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR-----------------
            120       130       140       150                      

     180       190       200       210       220       230         
pF1KB8 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI
                    :.:::::..  : .::::::.::.::::::::::: :::::.::::.
NP_001 -------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM
                      160       170       180       190       200  

     240        
pF1KB8 SLKQAPLVH
       ::::.::  
NP_001 SLKQTPLSR
            210 




248 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:41:44 2016 done: Fri Nov  4 10:41:45 2016
 Total Scan time:  6.530 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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