Result of FASTA (omim) for pF1KB8157
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8157, 549 aa
  1>>>pF1KB8157 549 - 549 aa - 549 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5576+/-0.000369; mu= 9.5710+/- 0.023
 mean_var=158.3435+/-30.904, 0's: 0 Z-trim(118.3): 21  B-trim: 1400 in 1/54
 Lambda= 0.101923
 statistics sampled from 31109 (31130) to 31109 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.365), width:  16
 Scan time: 10.890

The best scores are:                                      opt bits E(85289)
NP_055181 (OMIM: 608011) guanine nucleotide-bindin ( 549) 3571 537.2 5.1e-152
NP_996561 (OMIM: 608011) guanine nucleotide-bindin ( 537) 3495 526.0 1.2e-148
NP_996562 (OMIM: 608011) guanine nucleotide-bindin ( 537) 3495 526.0 1.2e-148
NP_061940 (OMIM: 300873) guanine nucleotide-bindin ( 582)  970 154.7 7.2e-37
NP_001171748 (OMIM: 300873) guanine nucleotide-bin ( 582)  970 154.7 7.2e-37
NP_001310553 (OMIM: 609365) nucleolar GTP-binding  ( 548)  356 64.4   1e-09
NP_037417 (OMIM: 609365) nucleolar GTP-binding pro ( 731)  356 64.5 1.3e-09
NP_001310552 (OMIM: 609365) nucleolar GTP-binding  ( 799)  340 62.2 7.1e-09


>>NP_055181 (OMIM: 608011) guanine nucleotide-binding pr  (549 aa)
 initn: 3571 init1: 3571 opt: 3571  Z-score: 2850.2  bits: 537.2 E(85289): 5.1e-152
Smith-Waterman score: 3571; 99.5% identity (100.0% similar) in 549 aa overlap (1-549:1-549)

               10        20        30        40        50        60
pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKQGHKKPRKDPGVPNSAPFKEAL
       ::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_055 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 SLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD
       :::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_055 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD
              490       500       510       520       530       540

                
pF1KB8 AYDFSTDYV
       :::::::::
NP_055 AYDFSTDYV
                

>>NP_996561 (OMIM: 608011) guanine nucleotide-binding pr  (537 aa)
 initn: 3495 init1: 3495 opt: 3495  Z-score: 2790.0  bits: 526.0 E(85289): 1.2e-148
Smith-Waterman score: 3495; 99.4% identity (100.0% similar) in 537 aa overlap (13-549:1-537)

               10        20        30        40        50        60
pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKQGHKKPRKDPGVPNSAPFKEAL
                   ::::::::::::::::::::::::::.:::::::::::::::::::::
NP_996             MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL
                           10        20        30        40        

               70        80        90       100       110       120
pF1KB8 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
       50        60        70        80        90       100        

              130       140       150       160       170       180
pF1KB8 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
      110       120       130       140       150       160        

              190       200       210       220       230       240
pF1KB8 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
      170       180       190       200       210       220        

              250       260       270       280       290       300
pF1KB8 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
      230       240       250       260       270       280        

              310       320       330       340       350       360
pF1KB8 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
      290       300       310       320       330       340        

              370       380       390       400       410       420
pF1KB8 SLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
      350       360       370       380       390       400        

              430       440       450       460       470       480
pF1KB8 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
      410       420       430       440       450       460        

              490       500       510       520       530       540
pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD
       :::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_996 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD
      470       480       490       500       510       520        

                
pF1KB8 AYDFSTDYV
       :::::::::
NP_996 AYDFSTDYV
      530       

>>NP_996562 (OMIM: 608011) guanine nucleotide-binding pr  (537 aa)
 initn: 3495 init1: 3495 opt: 3495  Z-score: 2790.0  bits: 526.0 E(85289): 1.2e-148
Smith-Waterman score: 3495; 99.4% identity (100.0% similar) in 537 aa overlap (13-549:1-537)

               10        20        30        40        50        60
pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKQGHKKPRKDPGVPNSAPFKEAL
                   ::::::::::::::::::::::::::.:::::::::::::::::::::
NP_996             MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL
                           10        20        30        40        

               70        80        90       100       110       120
pF1KB8 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
       50        60        70        80        90       100        

              130       140       150       160       170       180
pF1KB8 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
      110       120       130       140       150       160        

              190       200       210       220       230       240
pF1KB8 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
      170       180       190       200       210       220        

              250       260       270       280       290       300
pF1KB8 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
      230       240       250       260       270       280        

              310       320       330       340       350       360
pF1KB8 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
      290       300       310       320       330       340        

              370       380       390       400       410       420
pF1KB8 SLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
      350       360       370       380       390       400        

              430       440       450       460       470       480
pF1KB8 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
      410       420       430       440       450       460        

              490       500       510       520       530       540
pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD
       :::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_996 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD
      470       480       490       500       510       520        

                
pF1KB8 AYDFSTDYV
       :::::::::
NP_996 AYDFSTDYV
      530       

>>NP_061940 (OMIM: 300873) guanine nucleotide-binding pr  (582 aa)
 initn: 887 init1: 384 opt: 970  Z-score: 782.9  bits: 154.7 E(85289): 7.2e-37
Smith-Waterman score: 970; 37.5% identity (69.8% similar) in 437 aa overlap (16-443:6-441)

               10        20        30           40        50       
pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHR---KLRKEAKKQGHKKPRKDPGVPNSAPFK
                      ::  :  .  . :..      . ::..:.:   : :..:. .  .
NP_061           MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPN
                         10        20        30        40        50

        60        70        80        90        100       110      
pF1KB8 EALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTE
       .   :::::.:. .::....:.  :..: .:.: .:.   :.   . :  .::  : . .
NP_061 DHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELN
               60        70        80        90       100       110

        120       130       140       150       160        170     
pF1KB8 NKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVL
          .   . ..: : .:..::.: :::.:::::::::::::: :.:::.... :.:::::
NP_061 MFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVL
              120       130       140       150       160       170

         180       190       200       210       220        230    
pF1KB8 ILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPF-RSEVC
       .::: :::::: .:.::.::..:::::.:.:::. . :.     : . . .  . .:..:
NP_061 VLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKAC
              180       190       200       210       220       230

          240       250         260       270       280       290  
pF1KB8 FGKEGLWKLLGGFQET--CSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSM
       :: :.: ..::.. .       :::::.:.:::::::.:::::. . :.::.  :.:. :
NP_061 FGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFM
              240       250       260       270       280       290

            300       310       320        330       340       350 
pF1KB8 QVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIE-VVKPMEAASAILSQADARQVVL
       : : ::: : ..:.:... .: ::  .  ::. . .. .. :.  . .::.. . ...  
NP_061 QEVYLDKFIRLLDAPGIVPGP-NSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISN
              300       310        320       330       340         

             360       370       380       390       400       410 
pF1KB8 KYTVPGYRNSLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTP
        : : :.... .:.: .:.: : ..:::. . : ::: . ..:.......:  ::.. : 
NP_061 YYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTL
     350       360       370       380       390       400         

             420       430       440       450       460       470 
pF1KB8 PPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHE
       : ...  :: .:   :..:. :. : .... .                            
NP_061 PTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTK
     410       420       430       440       450       460         

             480       490       500       510       520       530 
pF1KB8 ELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFI
                                                                   
NP_061 IADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRI
     470       480       490       500       510       520         

>>NP_001171748 (OMIM: 300873) guanine nucleotide-binding  (582 aa)
 initn: 887 init1: 384 opt: 970  Z-score: 782.9  bits: 154.7 E(85289): 7.2e-37
Smith-Waterman score: 970; 37.5% identity (69.8% similar) in 437 aa overlap (16-443:6-441)

               10        20        30           40        50       
pF1KB8 MKRPKLKKASKRMTCHKRYKIQKKVREHHR---KLRKEAKKQGHKKPRKDPGVPNSAPFK
                      ::  :  .  . :..      . ::..:.:   : :..:. .  .
NP_001           MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPN
                         10        20        30        40        50

        60        70        80        90        100       110      
pF1KB8 EALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTE
       .   :::::.:. .::....:.  :..: .:.: .:.   :.   . :  .::  : . .
NP_001 DHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELN
               60        70        80        90       100       110

        120       130       140       150       160        170     
pF1KB8 NKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVL
          .   . ..: : .:..::.: :::.:::::::::::::: :.:::.... :.:::::
NP_001 MFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVL
              120       130       140       150       160       170

         180       190       200       210       220        230    
pF1KB8 ILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPF-RSEVC
       .::: :::::: .:.::.::..:::::.:.:::. . :.     : . . .  . .:..:
NP_001 VLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKAC
              180       190       200       210       220       230

          240       250         260       270       280       290  
pF1KB8 FGKEGLWKLLGGFQET--CSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSM
       :: :.: ..::.. .       :::::.:.:::::::.:::::. . :.::.  :.:. :
NP_001 FGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFM
              240       250       260       270       280       290

            300       310       320        330       340       350 
pF1KB8 QVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIE-VVKPMEAASAILSQADARQVVL
       : : ::: : ..:.:... .: ::  .  ::. . .. .. :.  . .::.. . ...  
NP_001 QEVYLDKFIRLLDAPGIVPGP-NSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISN
              300       310        320       330       340         

             360       370       380       390       400       410 
pF1KB8 KYTVPGYRNSLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTP
        : : :.... .:.: .:.: : ..:::. . : ::: . ..:.......:  ::.. : 
NP_001 YYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTL
     350       360       370       380       390       400         

             420       430       440       450       460       470 
pF1KB8 PPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHE
       : ...  :: .:   :..:. :. : .... .                            
NP_001 PTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTK
     410       420       430       440       450       460         

             480       490       500       510       520       530 
pF1KB8 ELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFI
                                                                   
NP_001 IADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRI
     470       480       490       500       510       520         

>>NP_001310553 (OMIM: 609365) nucleolar GTP-binding prot  (548 aa)
 initn: 584 init1: 177 opt: 356  Z-score: 295.3  bits: 64.4 E(85289): 1e-09
Smith-Waterman score: 585; 29.8% identity (60.1% similar) in 426 aa overlap (109-502:3-405)

       80        90       100       110       120       130        
pF1KB8 KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVI
                                     : :: .  ..    : .::...  :: :::
NP_001                             MIESGLINEAQEEIYKKGQSKRIW-GELYKVI
                                           10        20         30 

      140       150       160        170       180       190       
pF1KB8 EASDVVLEVLDARDPLGCRCPQVEEAIVQ-SGQKKLVLILNKSDLVPKENLESWLNYLKK
       ..::::..:::::::.: : :..:  . . .  :.:...::: ::::    . :.  :..
NP_001 DSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQ
              40        50        60        70        80        90 

       200        210       220       230       240       250      
pF1KB8 ELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIR
       . ::..:.:: :.:  :: . . ..             :::           .: .: : 
NP_001 DYPTLAFHASLTNPFGKGAFIQLLRQ------------FGK----------LHTDKKQIS
             100       110                   120                   

        260       270       280       290       300       310      
pF1KB8 VGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNS
       :: ::.:::::::.::.:.....:::.   : :.  : . : ..: .:: :. .    .:
NP_001 VGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDS
     130       140       150       160       170       180         

        320       330        340       350       360       370     
pF1KB8 SSALALRSPASIEVVK-PMEAASAILSQADARQVVLKYTVPGYRNSLEFFTMLAQRRGMH
        . ..:.. ...: .: : .  .:.: .:  . .   : . ...:. .:.  :: : :  
NP_001 ETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKL
     190       200       210       220       230       240         

         380       390       400         410          420       430
pF1KB8 QKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS--WTPP---PYFNESIVVDMKSGFNLE
        ::: :... ..:.. ..:  . . .. .::..   . :   :  .  .: .  ..   :
NP_001 LKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGE
     250       260       270       280       290       300         

              440              450              460                
pF1KB8 ELEKNNAQSIRAI------KGPHL-ANS----ILF---QSSGLTNGI----------IEE
       :. .. ... ..:      .. :  ::.    ::    :. :  : .          .: 
NP_001 EVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEV
     310       320       330       340       350       360         

        470       480       490       500       510       520      
pF1KB8 KDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQS
       .:..::: . .....::.:...:. .:. .:  .::                        
NP_001 SDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLD
     370       380       390       400       410       420         

        530       540                                              
pF1KB8 TRSFILDKIIEEDDAYDFSTDYV                                     
                                                                   
NP_001 KAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQREEEQEHSNK
     430       440       450       460       470       480         

>>NP_037417 (OMIM: 609365) nucleolar GTP-binding protein  (731 aa)
 initn: 584 init1: 177 opt: 356  Z-score: 293.6  bits: 64.5 E(85289): 1.3e-09
Smith-Waterman score: 580; 30.1% identity (60.7% similar) in 412 aa overlap (123-502:200-588)

            100       110       120       130       140       150  
pF1KB8 ETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARD
                                     : .::...  :: :::..::::..::::::
NP_037 STESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIW-GELYKVIDSSDVVVQVLDARD
     170       180       190       200        210       220        

            160        170       180       190       200        210
pF1KB8 PLGCRCPQVEEAIVQ-SGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKP
       :.: : :..:  . . .  :.:...::: ::::    . :.  :... ::..:.:: :.:
NP_037 PMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNP
      230       240       250       260       270       280        

              220       230       240       250       260       270
pF1KB8 KDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSI
         :: . . ..             :::           .: .: : :: ::.:::::::.
NP_037 FGKGAFIQLLRQ------------FGK----------LHTDKKQISVGFIGYPNVGKSSV
      290       300                             310       320      

              280       290       300       310       320       330
pF1KB8 INSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEV
       ::.:.....:::.   : :.  : . : ..: .:: :. .    .: . ..:.. ...: 
NP_037 INTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEK
        330       340       350       360       370       380      

               340       350       360       370       380         
pF1KB8 VK-PMEAASAILSQADARQVVLKYTVPGYRNSLEFFTMLAQRRGMHQKGGIPNVEGAAKL
       .: : .  .:.: .:  . .   : . ...:. .:.  :: : :   ::: :... ..:.
NP_037 IKSPEDHIGAVLERAKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKM
        390       400       410       420       430       440      

     390       400         410          420       430       440    
pF1KB8 LWSEWTGASLAYYCHPPTS--WTPP---PYFNESIVVDMKSGFNLEELEKNNAQSIRAI-
       . ..:  . . .. .::..   . :   :  .  .: .  ..   ::. .. ... ..: 
NP_037 VLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESII
        450       460       470       480       490       500      

                 450              460                 470       480
pF1KB8 -----KGPHL-ANS----ILF---QSSGLTNGI----------IEEKDIHEELPKRKERK
            .. :  ::.    ::    :. :  : .          .: .:..::: . ....
NP_037 KEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEE
        510       520       530       540       550       560      

              490       500       510       520       530       540
pF1KB8 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDD
       .::.:...:. .:. .:  .::                                      
NP_037 EEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISK
        570       580       590       600       610       620      

>>NP_001310552 (OMIM: 609365) nucleolar GTP-binding prot  (799 aa)
 initn: 584 init1: 177 opt: 340  Z-score: 280.3  bits: 62.2 E(85289): 7.1e-09
Smith-Waterman score: 537; 27.9% identity (56.8% similar) in 458 aa overlap (123-502:200-656)

            100       110       120       130       140       150  
pF1KB8 ETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARD
                                     : .::...  :: :::..::::..::::::
NP_001 STESYDQGKDRDLVTEDTGVRNEAQEEIYKKGQSKRIW-GELYKVIDSSDVVVQVLDARD
     170       180       190       200        210       220        

            160        170       180       190       200        210
pF1KB8 PLGCRCPQVEEAIVQ-SGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKP
       :.: : :..:  . . .  :.:...::: ::::    . :.  :... ::..:.:: :.:
NP_001 PMGTRSPHIETYLKKEKPWKHLIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNP
      230       240       250       260       270       280        

              220       230       240                              
pF1KB8 KDKGKITKRVKAKKNAAPFRSEVCFGKEGL------W-----------KLLGGFQ-----
         :: . . ..   .   .  .. .:  ::      :           . :  :.     
NP_001 FGKGAFIQLLRQFGKPWHLTFHALLGFPGLLCILCPWSPCSFYVLWLERALPKFKLQIPG
      290       300       310       320       330       340        

                         250            260       270       280    
pF1KB8 -------------------ETCS-----KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGV
                           .::     : : :: ::.:::::::.::.:.....:::. 
NP_001 QTSAPEGSRGTRLPYQILKASCSLHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAP
      350       360       370       380       390       400        

          290       300       310       320       330        340   
pF1KB8 SMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQ
         : :.  : . : ..: .:: :. .    .: . ..:.. ...: .: : .  .:.: .
NP_001 IAGETKVWQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLER
      410       420       430       440       450       460        

           350       360       370       380       390       400   
pF1KB8 ADARQVVLKYTVPGYRNSLEFFTMLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYC
       :  . .   : . ...:. .:.  :: : :   ::: :... ..:.. ..:  . . .. 
NP_001 AKPEYISKTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFV
      470       480       490       500       510       520        

             410          420       430       440              450 
pF1KB8 HPPTS--WTPP---PYFNESIVVDMKSGFNLEELEKNNAQSIRAI------KGPHL-ANS
       .::..   . :   :  .  .: .  ..   ::. .. ... ..:      .. :  ::.
NP_001 KPPNAEPLVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANT
      530       540       550       560       570       580        

                    460                 470       480       490    
pF1KB8 ----ILF---QSSGLTNGI----------IEEKDIHEELPKRKERKQEEREDDKDSDQET
           ::    :. :  : .          .: .:..::: . .....::.:...:. .:.
NP_001 EMQQILTRVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEES
      590       600       610       620       630       640        

          500       510       520       530       540              
pF1KB8 VDEEVDENSSGMFAAEETGEALSEETTAGQQSTRSFILDKIIEEDDAYDFSTDYV     
        .:  .::                                                    
NP_001 SSEPEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQR
      650       660       670       680       690       700        




549 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:05:10 2016 done: Fri Nov  4 10:05:11 2016
 Total Scan time: 10.890 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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